2018 25th National and 3rd International Iranian Conference on Biomedical Engineering (ICBME)最新文献_第7页

A novel frame rate up-conversion method to decrease blocking and blurring factors using none rigid image registration on medical videos 一种新的帧率上转换方法，利用非刚性图像配准减少医学视频的阻塞和模糊因素

2018 25th National and 3rd International Iranian Conference on Biomedical Engineering (ICBME) Pub Date : 2018-11-01 DOI: 10.1109/ICBME.2018.8703560

Sobhan Haghparast, E. Fatemizadeh

引用次数: 0

Discovering Informative Regions in Iris Images to Predict Diabetes 发现虹膜图像中的信息区域以预测糖尿病

2018 25th National and 3rd International Iranian Conference on Biomedical Engineering (ICBME) Pub Date : 2018-11-01 DOI: 10.1109/ICBME.2018.8703564

Parsa Moradi, Naghme Nazer, A. K. Ahmadi, H. Mohammadzade, Hasan Khojasteh Jafari

引用次数: 1

Design, Fabrication and Verification of Continuous Passive Motion Equipment for the Index Finger 食指连续被动运动装置的设计、制造与验证

2018 25th National and 3rd International Iranian Conference on Biomedical Engineering (ICBME) Pub Date : 2018-11-01 DOI: 10.1109/ICBME.2018.8703586

Z. Arjmandi, Dr. Firooz Bakhtiari Nejad, Dr. Mohammad Ali Ahmadi Pajouh

引用次数: 0

Development of an Efficient Centrifugal Microfluidic Platform for Automated Chemical Cell Lysis 高效离心微流控自动化化学细胞裂解平台的研制

2018 25th National and 3rd International Iranian Conference on Biomedical Engineering (ICBME) Pub Date : 2018-11-01 DOI: 10.1109/ICBME.2018.8703533

Arash Khorrami Jahromi, M. Saadatmand, Hamed Shieh, M. Eghbal, L. P. Yeganeh

{"title":"Development of an Efficient Centrifugal Microfluidic Platform for Automated Chemical Cell Lysis","authors":"Arash Khorrami Jahromi, M. Saadatmand, Hamed Shieh, M. Eghbal, L. P. Yeganeh","doi":"10.1109/ICBME.2018.8703533","DOIUrl":"https://doi.org/10.1109/ICBME.2018.8703533","url":null,"abstract":"Applications of microfluidic technologies in medical diagnostics continue to increase, particularly in the field of nucleic acid diagnostics. Although much attention has been focused on the development of nucleic acid amplification and detection platforms, cell lysis procedure, as one of the most fundamental steps of sample preparation have not been taken into consideration sufficiently. In this paper, the design and characterization of a novel centrifugal microfluidic platform for chemical cell lysis is presented. The developed configuration employs passive pneumatic reciprocating mixer and siphon valve for rigorous mixing of lysis buffer and cell samples alongside precise control over fluid flow. Experiments were conducted with white blood cells, separated from human whole blood, to demonstrate the performance. Compared to commercial manual protocol for cell lysing, the experimental results indicated that the proposed method is greatly effective in realizing a chemical cell lysis system on lab-on-a-disc (LoaD) with high throughput in terms of purity and yield of DNA. The developed system provides efficient, simple, and fully automated chemical cell lysis which can be easily integrated into sample-to-answer systems with applications in point-of-care settings","PeriodicalId":338286,"journal":{"name":"2018 25th National and 3rd International Iranian Conference on Biomedical Engineering (ICBME)","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126376808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Modeling and Simulation of EMG Signal and H-Reflex in Healthy Human Subject 健康人体肌电信号和h反射的建模与仿真

2018 25th National and 3rd International Iranian Conference on Biomedical Engineering (ICBME) Pub Date : 2018-11-01 DOI: 10.1109/ICBME.2018.8703535

Seyyedeh Ensiyeh Hashemi, Mohammad Ali Ahmadi-Pajouh, Elham Shamsi

{"title":"Modeling and Simulation of EMG Signal and H-Reflex in Healthy Human Subject","authors":"Seyyedeh Ensiyeh Hashemi, Mohammad Ali Ahmadi-Pajouh, Elham Shamsi","doi":"10.1109/ICBME.2018.8703535","DOIUrl":"https://doi.org/10.1109/ICBME.2018.8703535","url":null,"abstract":"Electromyography (EMG) is a signal representing the activity of skeletal muscles. Besides, H-reflex and M-wave are two responses to the electrical stimulation of the nerve, and they appear in EMG. In this paper, the purpose was to model the recorded EMG from the FCR muscle in response to both the electrical stimulation and the brain commands during motor imagery. This model could capture the qualitative behavior of the H-reflex and how physiological variables change its waveform. Two mathematical models of the EMG signal (i.e., baseline EMG and H-reflex) were developed. These models were designed to simulate the EMG signal with respect to the intensity of contraction and electrical stimulation. Also, the effect of the brain descending pathways was considered with a parameter. We used the Hodgkin-Huxley (HH) and Morris-Lecar (ML) equations for the action potentials (APs) of motor neurons and muscle fibers, respectively. After processing the sensory signals in the spinal cord, the response pulses are transmitted from the spinal cord to the muscle. When the AP is generated, the spike train passes to the muscle fiber. Each muscle contains several motor units (MUs), each of which consists of a motor neuron and its innervated muscle fibers. Moreover, summation of the total activity of the muscle fibers within each MU forms its activity. Likewise, total muscle activity (i.e., EMG) is the summation of the activity of all MUs. The H-reflex and M-wave models were developed by applying electrical stimulation in the EMG model. Moreover, mean square error (MSE) for the model was 0.00027%, and Spearman`s correlation coefficient was 0.722 (p-value < 0.05).","PeriodicalId":338286,"journal":{"name":"2018 25th National and 3rd International Iranian Conference on Biomedical Engineering (ICBME)","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125003694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis of Hyaluronic acid-Tyramine Microgels for Sustained Protein Release 蛋白缓释透明质酸酪胺微凝胶的合成

2018 25th National and 3rd International Iranian Conference on Biomedical Engineering (ICBME) Pub Date : 2018-07-02 DOI: 10.1109/ICBME.2018.8703588

Elaheh Jooybar, M. Abdekhodaie, P. Dijkstra

{"title":"Synthesis of Hyaluronic acid-Tyramine Microgels for Sustained Protein Release","authors":"Elaheh Jooybar, M. Abdekhodaie, P. Dijkstra","doi":"10.1109/ICBME.2018.8703588","DOIUrl":"https://doi.org/10.1109/ICBME.2018.8703588","url":null,"abstract":"Microgels are hydrophilic polymer matrix with high water content suitable for encapsulation and delivery of biomolecules. In this study, hyaluronic acid (HA) microgels were synthesized using a water in oil emulsion method. First, hyaluronic acid was modified with tyramine, and then the microemulsion was produced by homogenizing the polymer solution in isooctane as an oil phase. HA microdroplets were crosslinked via enzymatic method by addition of horseradish peroxidase (enzyme) and hydrogen peroxide, and stable microgels were produced in a mild crosslinking reaction. According to the results, larger microgels were achieved by increasing the initial polymer concentration. Two sample proteins, Bovine serum albumin (BSA) and lysozyme, were incorporated in the polymer network to investigate the encapsulation efficiency of the microgels. The results demonstrated that the proposed method has a high efficiency for protein encapsulation (> 70%). The release profiles showed that lysozyme, as a cationic protein, was released in a sustained manner over a period of two weeks. However, BSA, as a negatively charged protein, showed a faster release rate. The simple method of microgel fabrication, besides the sustained release of the encapsulated proteins, makes the HA microgels a promising vehicle for delivery of cationic proteins.","PeriodicalId":338286,"journal":{"name":"2018 25th National and 3rd International Iranian Conference on Biomedical Engineering (ICBME)","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130825555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1