Journal of SAFOMS最新文献

Comparison of Antibiotics and Prebiotics in Treatment of Pelvic Inflammatory Disease 抗生素与益生元治疗盆腔炎的比较

Journal of SAFOMS Pub Date : 2020-08-10 DOI: 10.5005/JP-JOURNALS-10032-1204

Preeti Kale, K. Jangale, Amruta Kakade

{"title":"Comparison of Antibiotics and Prebiotics in Treatment of Pelvic Inflammatory Disease","authors":"Preeti Kale, K. Jangale, Amruta Kakade","doi":"10.5005/JP-JOURNALS-10032-1204","DOIUrl":"https://doi.org/10.5005/JP-JOURNALS-10032-1204","url":null,"abstract":"\u0000\u0000\u0000Pelvic inflammatory disease (PID) refers to an infectious and inflammatory disorder of the female upper genital tract. It is common among young sexually active individuals and is a major health problem both in developed and developing countries. It is usually a polymicrobial infection; however, Chlamydia trachomatis is the commonest causative agent transmitted sexually. Pelvic inflammatory disease is diagnosed by history and clinical examination. The treatment is initially empiric. Only antibiotics are good in treatment for PID and “antibiotics with prebiotics” are a new promising treatment mode for the same. This comparative study aimed to measure efficiency and compliance of only antibiotics vs antibiotics with prebiotics in the treatment of mild, uncomplicated acute PID.\u0000\u0000\u0000\u0000Multispecialty Hospital Pune. Duration: 6 months.\u0000\u0000\u0000\u0000A descriptive cross-sectional study was conducted in randomly selected 28 consecutive outpatients with mild uncomplicated acute PID. Comparative outcome of antibiotics and antibiotics with prebiotics in correlation with the reduction of amount, consistency, and malodor of vaginal discharge along with the reduction in fornical tenderness, compliance, and frequency of adverse drug reactions was done.\u0000\u0000\u0000\u0000Among 28 cases, 14 (50%) were treated with oral antibiotics and 14 (50%) with oral antibiotics with prebiotics. Comparative analysis on the reduction of amount, consistency, malodor of vaginal discharge, and reduction of fornical tenderness was significant, showing antibiotics with prebiotics more effective than antibiotics. Besides, compliance was better and there were fewer adverse drug reactions with antibiotics with prebiotics.\u0000\u0000\u0000\u0000Antibiotics with prebiotics have better efficiency and compliance over only antibiotics in the treatment of mild, uncomplicated, acute PID.\u0000\u0000Kale PA, Jangale KG, Kakade A. Comparison of Antibiotics and Prebiotics in Treatment of Pelvic Inflammatory Disease. J South Asian Feder Menopause Soc 2020;8(1):24–26.\u0000","PeriodicalId":338227,"journal":{"name":"Journal of SAFOMS","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123040322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}