HIV & AIDS Review最新文献_第4页

Factors associated with anxiety in children and adolescents with HIV infection 感染艾滋病毒的儿童和青少年焦虑相关因素

HIV & AIDS Review Pub Date : 1900-01-01 DOI: 10.5114/hivar.2022.115828

I. W. Satriawibawa, K. Wati, I. G. Windiani, I. G. A. Adnyana, Putu Diah Vedaswari, I. Sutawan, K. Witarini, Ni Luh Sukma Pratiwi Murti

引用次数: 0

Challenges in receiving HIV prevention services by female sex workers: a qualitative study 女性性工作者在接受艾滋病毒预防服务方面的挑战:一项定性研究

HIV & AIDS Review Pub Date : 1900-01-01 DOI: 10.5114/hivar.2023.124893

Mehrdad Eftekhar-Ardebili, Yosra Raziani, Colleen Bernstein, Parisa Khodakhah, F. Noodeh, H. Ranjbar

引用次数: 0

Drug-selective pressure effect on HIV integrase mutations in antiretroviral naïve and experienced patients 药物选择压力对抗逆转录病毒病毒整合酶突变naïve和经验患者的影响

HIV & AIDS Review Pub Date : 1900-01-01 DOI: 10.5114/hivar.2023.127727

Parya Basimi, M. Farrokhi, Maryam Ghanbari, S. D. Dehghan Manshadi, M. Naghib, K. Baesi

{"title":"Drug-selective pressure effect on HIV integrase mutations in antiretroviral naïve and experienced patients","authors":"Parya Basimi, M. Farrokhi, Maryam Ghanbari, S. D. Dehghan Manshadi, M. Naghib, K. Baesi","doi":"10.5114/hivar.2023.127727","DOIUrl":"https://doi.org/10.5114/hivar.2023.127727","url":null,"abstract":"Introduction: Resistance to antiretroviral drugs is a serious problem often related to selective drug-induced pressure and sub-optimal drug dosing. This study aimed to investigate drug resistance-associated mutations in human immunodeficiency virus type 1 (HIV-1) integrase gene caused by the drug pressure of reverse transcriptase inhibitors (RTIs) and protease inhibitors (PIs). Material and methods: For this purpose, RNA of 50 HIV-infected patients (25 drug-naïve patients and 25 patients under antiretroviral therapy [INI naive]) was extracted and one step RT-nested PCR was carried out on HIV integrase (IN). Then, gene sequences were analyzed to determine sub-types and antiretroviral resistance-associated mutations (RAMs). Results: Phylogenetic analysis revealed that recombinant sub-type CRF35-AD was the most prevalent in all patients (87.2%), followed by A1 sub-type (12.8%). Among the 25 ART-experienced patients, two mutations (N155I, G163R) associated with resistance to integrase inhibitors (INI) were found. Among the 25 naïve patients, several polymorphisms were observed, which was also lower in this group than in the ART group. Conclusions: The results of this study indicated that the integrase mutations can be caused by the effect of selective pressure induced by antiviral agents, such as RTIs and PIs. Therefore, examination of the integrase drug resistance mutations is recommended before starting treatment in Iran.","PeriodicalId":338023,"journal":{"name":"HIV & AIDS Review","volume":"72 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114802912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence of post-traumatic stress disorder in HIV-positive women and its’ related factors in an Iranian setting 伊朗艾滋病病毒阳性妇女创伤后应激障碍患病率及其相关因素

HIV & AIDS Review Pub Date : 1900-01-01 DOI: 10.5114/hivar.2022.117237

F. Najafi, M. Vizheh, Zahra Behboodi Moghadam, E. Rezaei, S. Saeieh, H. Koochak

{"title":"Prevalence of post-traumatic stress disorder in HIV-positive women and its’ related factors in an Iranian setting","authors":"F. Najafi, M. Vizheh, Zahra Behboodi Moghadam, E. Rezaei, S. Saeieh, H. Koochak","doi":"10.5114/hivar.2022.117237","DOIUrl":"https://doi.org/10.5114/hivar.2022.117237","url":null,"abstract":"Introduction: Human immunodeficiency virus (HIV) infection is one of the most important human issues regarding health, social, and economic aspects. Possibility of being infected by the virus in women is as twice large compared to their male counterparts. Diagnosis of HIV disease could be a traumatic event leading to the onset and development of post-traumatic stress disorder (PTSD), which itself has many negative consequences. Hence, the aim of this study was to examine the prevalence and factors associated with PTSD in HIV patients to improve their care. Material and methods: This study was a cross-sectional study carried out in AIDS Research Center, Clinic and Gynecology Ward, Imam Khomeini Hospital, during 2018-2019. Participants were selected using convenience sampling. Data were collected using two questionnaires, including Mississippi scale and demographic questionnaire. Data were analyzed using SPSS version 16. Results: In this research, the mean score of PTSD in HIV-positive women was 100.45 (± 21.86), with 44.5% (134 individuals) suffering from PTSD. Also, death of a family member, infertility history, housing status, history of violence, type and number of delivery, children’s affection, education level, and history of imprisonment had the most significant association in HIV-positive women at 95% confidence level. Conclusions: The results of this study highlighted the need to prioritize psychological (death of a family member and history of violence), economic and social (housing status), and medical needs (infertility history, childbirth, and status of children’s HIV infection) of HIV-positive women who are experiencing various factors causing PTSD.","PeriodicalId":338023,"journal":{"name":"HIV & AIDS Review","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126393226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Linkage to care to reduce the gap in HIV treatment of people living with HIV/AIDS in Peru: 2016-2019 experience 联系护理，以缩小秘鲁艾滋病毒/艾滋病感染者在艾滋病毒治疗方面的差距:2016-2019年的经验

HIV & AIDS Review Pub Date : 1900-01-01 DOI: 10.5114/hivar.2023.125556

Roberto Carrasco Navarro, Mónica Guevara, Maribel Caballero, Nadya Bravo, Juan Miñano, L. Mestanza, M. Muñoz, J. Sebastián, Jenny Carranza

引用次数: 0

ENGAGE-A3 model: communication risk to involve Myanmar workers in AIDS prevention ENGAGE-A3模式:沟通风险，让缅甸工作人员参与艾滋病预防

HIV & AIDS Review Pub Date : 1900-01-01 DOI: 10.5114/hivar.2022.115679

Smith Boonchutima, Suchitra Sukonthasab, Parichart Sthapitanonda

引用次数: 0

Evaluation of the self-care needs in knowledge, belief and behavior in male students regarding protection against HIV 男大学生艾滋病防护知识、信念、行为自我保健需求评价

HIV & AIDS Review Pub Date : 1900-01-01 DOI: 10.5114/hivar.2022.120212

Mohamad Naraghi, B. Ataei, A. Mirzazadeh, Zahra Boroumandfar

引用次数: 0

Late presentation: a stumbling block to HIV viral suppression in a low income country 后期报告:低收入国家抑制艾滋病毒的绊脚石

HIV & AIDS Review Pub Date : 1900-01-01 DOI: 10.5114/hivar.2022.115837

E. Bilaro, Shamsherali Noormohamed

{"title":"Late presentation: a stumbling block to HIV viral suppression in a low income country","authors":"E. Bilaro, Shamsherali Noormohamed","doi":"10.5114/hivar.2022.115837","DOIUrl":"https://doi.org/10.5114/hivar.2022.115837","url":null,"abstract":"Introduction: Tenofovir-based regimens have been recently introduced as first-line antiretroviral treatment (ART) to human immunodeficiency virus (HIV) patients in Tanzania. Limited information on HIV viral suppression and its’ associated factors exists in Tanzania since the adoption of this inter-vention at a public health level. The aim of the present study was to determine HIV viral suppression rate and assess its’ associated factors among patients attending Temeke Regional Referral Hospital care and treatment clinic after twelve months of using antiretroviral therapy. Material and methods: Hospital-based cross-sectional study was performed to assess factors associated with HIV viral suppression. Viral load suppression was defined as HIV-RNA below 50 copies/ml, and late presentation was defined in a person who presented to care and treatment facility with WHO HIV clinical stage III or IV and/or baseline CD4+ T lymphocyte count of less than 350 cells/µl. Results: Among the 188 participants who were interviewed, a total of 149 (79.3%) achieved viral suppression after one year of using ART. Late presentation to health facility (OR = 3.4; 95% CI: 1.6-7.4; p < 0.01) was independently associated with inability to achieve viral suppression at 12 months. Conclusions: HIV testing services should be strengthened in order to achieve the UNAIDS 90-90-90 target through early detection of HIV disease.","PeriodicalId":338023,"journal":{"name":"HIV & AIDS Review","volume":"242 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132271718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Concomitant cancers in AIDS patients: a case report from Iran 艾滋病患者并发癌症:伊朗一例报告

HIV & AIDS Review Pub Date : 1900-01-01 DOI: 10.5114/hivar.2023.126558

P. Tabarsi, M. Nasirian, M. Marjani, A. Moniri

引用次数: 0

HIV & AIDS Review Pub Date : 1900-01-01 DOI: 10.5114/hivar.2023.124548

A. Wardhani, S. Haryanto, Teuku Fahmi, Muhammad Saud

引用次数: 0

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