Revista Romana de Pediatrie最新文献_第8页

Antimicrobial resistance: A new threat in the COVID-19 era? 抗菌素耐药性:COVID-19时代的新威胁?

Revista Romana de Pediatrie Pub Date : 2021-12-31 DOI: 10.37897/rjp.2021.4.7

L. Dracea

{"title":"Antimicrobial resistance: A new threat in the COVID-19 era?","authors":"L. Dracea","doi":"10.37897/rjp.2021.4.7","DOIUrl":"https://doi.org/10.37897/rjp.2021.4.7","url":null,"abstract":"During the COVID-19 pandemic antibiotic use considerably increased being partially justified by the fear of bacterial infection. Antibacterial resistance (ABR), due to increased and unjustified antibiotic use, is a major threat to the economy and global health. In pediatric practice, antibiotics are the most common prescribed substances, both in the community and hospital setting. Unjustified use, inappropriate doses and prescription duration promote antibacterial resistance and increase mortality. The majority of current health problems in children are viral infections, even the rates of infection are higher as in adults, fact that determines more frequent diagnostic uncertainties. More so, respiratory infections in children have a greater potential of excessive and incorrect use of antibiotics, that justifies protocol based evaluations, risk assessment and targeted treatment. The diversity and magnitude of clinical presentation of SARS-CoV-2 infection, along with early and long-term complications and sequelae, also noticed in pediatric practice, created the premises of increased use of antibiotics, aggravating the ABR. This is a challenge for the clinician during a period when development of new antibiotics is not a priority of the pharma industry anymore. Research of mechanisms that contribute to ABR, innovative therapies, expansion of genetics and implementation of antibiotic stewardship, together with stimulating pharma industry for developing of new substances, may have the potential of decreasing antibacterial resistance in an era of medical and economic uncertainties generated by the COVID-19 pandemic.","PeriodicalId":33512,"journal":{"name":"Revista Romana de Pediatrie","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41886265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Maternal diabetes and neonatal outcome 母亲糖尿病与新生儿结局

Revista Romana de Pediatrie Pub Date : 2021-12-31 DOI: 10.37897/rjp.2021.4.8

V. Varlas, M. Ciocârlan, R. Bohîlțea, Vlad Dima

引用次数: 0

Minimal invasive management of complete renoureteral duplication with upper pole megaureter in children 采用上极计治疗儿童完全性肾重复的微创治疗

Revista Romana de Pediatrie Pub Date : 2021-12-31 DOI: 10.37897/rjp.2021.4.12

D. Dobrițoiu, S. Tudorache, A. Stoica, D. Nedelcu, L. Ion, R. Bohîlțea

引用次数: 0

Ultrasonographic detection of gastroschisis in the first trimester: Actualities in pregnancy management and outcome 妊娠早期腹裂的超声检测：妊娠管理和结局的现状

Revista Romana de Pediatrie Pub Date : 2021-12-31 DOI: 10.37897/rjp.2021.4.5

Dragoş Tudorache, R. Bohîlțea, Paul Costin Pariza, Vlad Dima, C. Grigoriu, B. Mihai, C. Berceanu, R. Vlădăreanu

{"title":"Ultrasonographic detection of gastroschisis in the first trimester: Actualities in pregnancy management and outcome","authors":"Dragoş Tudorache, R. Bohîlțea, Paul Costin Pariza, Vlad Dima, C. Grigoriu, B. Mihai, C. Berceanu, R. Vlădăreanu","doi":"10.37897/rjp.2021.4.5","DOIUrl":"https://doi.org/10.37897/rjp.2021.4.5","url":null,"abstract":"Gastroschisis is a congenital anterior abdominal wall defect that occurs in 4 to 5 in 10,000 births, consisting in the evisceration of bowel in the amniotic cavity without a membranous covering. Gastroschisis cases can be detected during the first trimester using ultrasonography or at the beginning of the second trimester with a detection rate of 100%. Although an isolated condition in most of the cases, further complications such as malrotation, atresia, stenosis, perforation or volvulus can be associated. Periodic monitoring is required to assess the progress of the pregnancy with measurements of the level of amniotic fluid, fetal biometry and bowel diameters at every ultrasound examination. Gastroschisis is most frequently associated with oligohydramnios, intrauterine fetal growth restriction, increased bowel wall thickness and bowel dilatation. The outcome of the disease is favorable with a survival rate of around 90% for born infants. The long time on ventilator and multiple intestinal surgeries that delay the moment of oral feeding with a long-term use of total parental nutrition and short bowel syndrome are the most important comorbidities. Delivery is recommended at 38 weeks of gestation, preserving caesarean delivery for complicated gastroschisis. Although a complex pathology, gastroschisis is associated with normal intellectual development and few to none long-term complications.","PeriodicalId":33512,"journal":{"name":"Revista Romana de Pediatrie","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44500372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The international approach of pediatric thyroid nodules and thyroid differentiated carcinoma. The starting point for the Romanian pediatric guideline 儿童甲状腺结节和甲状腺分化癌的国际治疗方法。罗马尼亚儿科指南的起点

Revista Romana de Pediatrie Pub Date : 2021-12-31 DOI: 10.37897/rjp.2021.4.6

A. Ștefan, C. Blag, G. Popa, M. Dragomir, R. Cosnarovici, D. Piciu

{"title":"The international approach of pediatric thyroid nodules and thyroid differentiated carcinoma. The starting point for the Romanian pediatric guideline","authors":"A. Ștefan, C. Blag, G. Popa, M. Dragomir, R. Cosnarovici, D. Piciu","doi":"10.37897/rjp.2021.4.6","DOIUrl":"https://doi.org/10.37897/rjp.2021.4.6","url":null,"abstract":"Background. The incidence of pediatric differentiated thyroid carcinoma (DTC) is increasing even though that this is a rare disease. It is known that there are important differences between adults and children especially in clinical presentation and genetic alterations. The only guideline for the diagnostic and therapeutic approach for the children with thyroid nodules and differentiated thyroid carcinoma is the American Thyroid Association (ATA) guideline published in 2015, but there could be improvements that we need to highlight in order to reduce the apparition of comorbidities and to improve the quality of life. There is also no national guideline in Romania for the treatment of this pathology in children. Materials and methods. This study is a review of the literature published in the last 5 years concerning the diagnostic and treatment of the pediatric thyroid cancer. Results. The management of the children with the suspicion of thyroid nodule should be done in specialized centers in a specialized, multidisciplinary team, with high volume surgeons. The diagnostic approach should include genetic testing. The surgical management could be less radical in certain cases. The pre-surgical evaluation and intraoperative laryngeal nerve monitoring should reduce the apparition of comorbidities. Conclusion. A European and also a national guideline for the management of pediatric thyroid nodules and thyroid carcinoma is mandatory to reduce the apparition of comorbidities and to improve the quality of life of the patients.","PeriodicalId":33512,"journal":{"name":"Revista Romana de Pediatrie","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43992737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Retinoids and teratogenicity 类视网膜物质与致畸性

Revista Romana de Pediatrie Pub Date : 2021-12-31 DOI: 10.37897/rjp.2021.4.3

L. Pop, N. Bacalbaşa, I. Bălescu, Vlad Dima, R. Bohîlțea

引用次数: 0

Preauricular lymphadenopathy in a pediatric patient: A diagnostic pitfall 小儿耳前淋巴结病:一个诊断陷阱

Revista Romana de Pediatrie Pub Date : 2021-12-31 DOI: 10.37897/rjp.2021.4.11

D. Pleșca, Teodora Jescu, A. Zamfirescu, C. Soreanu, C. Ardeleanu, C. Comsa, I. Țincu

引用次数: 0

Risk factors and protective factors in pregnant adolescents 怀孕青少年的危险因素和保护因素

Revista Romana de Pediatrie Pub Date : 2021-12-31 DOI: 10.37897/rjp.2021.4.9

Andreea Giorgiana Mantescu, D. Iordăchescu, E. Vladislav, C. Gică, A. Panaitescu, G. Peltecu, N. Gică

引用次数: 0

Diagnostic challenges in Goldenhar syndrome – a case report Goldenhar综合征的诊断挑战- 1例报告

Revista Romana de Pediatrie Pub Date : 2021-12-31 DOI: 10.37897/rjp.2021.4.13

Paul Costin Pariza, Vlad Dima, C. Grigoriu, C. Berceanu, T. Georgescu, B. Mihai, C. Gheorghe, R. Bohîlțea

引用次数: 0

Epidemiology of acute pediatric poisonings complicated by cardiogenic shock – a 6-year study in a clinical toxicology unit 急性小儿中毒并发心源性休克的流行病学——临床毒理学单位的一项为期6年的研究

Revista Romana de Pediatrie Pub Date : 2021-12-31 DOI: 10.37897/rjp.2021.4.10

Cristina-Daniela Enache, Madalina Petran, Simona Stanca, V. Niţescu, C. Ulmeanu, R. Bohîlțea, C. I. Vivisenco

引用次数: 0