Blue Biotechnology最新文献

{"title":"Marennine-Like Pigments: Blue Diatom or Green Oyster Cult?","authors":"R. Gastineau, F. Prasetiya, Charlotte Falaise, Bruno Cognie, Priscilla Decottignies, M. Morançais, V. Méléder, N. Davidovich, F. Turcotte, R. Tremblay, Pamela Pasetto, J. Dittmer, J. Bardeau, Jean-Bernard Pouvreau, J. Mouget","doi":"10.1002/9783527801718.CH16","DOIUrl":"https://doi.org/10.1002/9783527801718.CH16","url":null,"abstract":"","PeriodicalId":333390,"journal":{"name":"Blue Biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126535901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cultivation and Conversion of Tropical Red Seaweed into Food and Feed Ingredients, Agricultural Biostimulants, Renewable Chemicals, and Biofuel","authors":"S. Suryanarayan, I. Neish, S. Nori, Nelson Vadassery","doi":"10.1002/9783527801718.CH8","DOIUrl":"https://doi.org/10.1002/9783527801718.CH8","url":null,"abstract":"","PeriodicalId":333390,"journal":{"name":"Blue Biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132812952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Marine Polysaccharides and Their Importance for Human Health","authors":"P. Laurienzo","doi":"10.1002/9783527801718.CH15","DOIUrl":"https://doi.org/10.1002/9783527801718.CH15","url":null,"abstract":"","PeriodicalId":333390,"journal":{"name":"Blue Biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134440205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of Marine Compounds to Treat Ischemic Diseases","authors":"C. Boisson‐Vidal","doi":"10.1002/9783527801718.CH9","DOIUrl":"https://doi.org/10.1002/9783527801718.CH9","url":null,"abstract":"Te marine reservoir, with its massive biodiversity, likely harbors numerous human drug candidates. Polysaccharides of various marine origins have shown to be good alternatives to mammalian polysaccharides. One well-known example is heparin, a sulfated polysaccharide used in the prevention of thrombosis and pulmonary embolism. Te oldest use of marine polysaccharides concerns those produced by algae. Tese products form the basis for an economically important and expanding global industry. Tis chapter provides a historical background to the discovery of the therapeutic potential of these marine compounds, together with their medical and biotechnological applications. Peripheral arterial disease (PAD) is a progressive disorder due to atherosclerosis (narrowing of the peripheral arteries, especially in the legs). Arterial flow is reduced or discontinuous, causing oxygen deprivation in the underlying tissues and possible tissue necrosis. Te primary aim of medical therapy is to increase arterial flow in the affected limb in order to relieve pain, heal trophic lesions, and avoid amputation. Anticoagulant, antithrombotic, and antiplatelet agents are used to reduce the risk of thrombus formation. Novel treatments such as therapeutic angiogenesis (promotion of new blood vessel growth) are in the development phase, with promising preclinical data. Fucoidan is a polysulfated L-fucose endowed with biological activities closely related to its chemical composition (especially the distribution of sulfate groups along its polyfucose backbone) and to its molecular weight. Fucoidans are highly soluble in water, nontoxic, and non-immunogenic. Details are provided below on its production and characterization and on the main chemical characteristics that influence their biological activities. Fucoidan exhibits venous and arterial antithrombotic properties in animal models. In animal experiments, fucoidan promoted the formation of new blood vessels, thereby preventing necrosis of ischemic tissue. It also recruits stem cells from bone marrow, further accelerating tissue healing. Te cellular and molecular mechanisms underlying fucoidan’s effects on angiogenesis are then addressed, beginning with a brief overview of blood vessel formation. Recent advances have been \u0000made in understanding how the interactions between these polyfucoses and adult stem cells contribute to new blood vessel formation after ischemic injury, notably via carbohydrates located mainly in the basement membrane and cell surface.","PeriodicalId":333390,"journal":{"name":"Blue Biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121622394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phytoplankton Glycerolipids: Challenging but Promising Prospects from Biomedicine to Green Chemistry and Biofuels","authors":"Josselin Lupette, E. Maréchal","doi":"10.1002/9783527801718.CH6","DOIUrl":"https://doi.org/10.1002/9783527801718.CH6","url":null,"abstract":"","PeriodicalId":333390,"journal":{"name":"Blue Biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120817881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Guanidinium Toxins: Natural Biogenic Origin, Chemistry, Biosynthesis, and Biotechnological Applications","authors":"L. Durán-Riveroll, A. Cembella, J. Correa-Basurto","doi":"10.1002/9783527801718.CH11","DOIUrl":"https://doi.org/10.1002/9783527801718.CH11","url":null,"abstract":"Neurotoxins belonging to the group of saxitoxin (STX) and tetrodotoxin (TTX) analogs are guanidinium alkaloids that share a common high affinity and ion flux blockage capacity for voltage-gated sodium ion channels (Nav. \u0000Members of the STX group, also known as paralytic shellfish toxins (PST), are produced among three genera of marine dinoflagellate and several genera of phylogenetically distant and primarily freshwater filamentous cyanobacteria. The origin of the biosynthetic genes in dinoflagellates remains controversial and may represent single or multiple horizontal gene transfer (HGT) events from progenitor eubacteria and/or cyanobacteria. The TTXs occur primarily among marine puffer fish and a host of terrestrial amphibians. The biosynthetic \u0000pathway has not been completely elucidated and the origin of tetrodotoxicity,including the syndrome puffer fish poisoning (PFP) in human seafood consumers,remains somewhat enigmatic. Although symbiotic bacteria are most often invoked as the source of TTX in macrofauna, endogenous biosynthesis independent of bacteria cannot be excluded. Integration of knowledge on the biogenic origins, linked to heterogeneity of the biogeographical and phylogenetic distribution of these respective toxin groups, provides the basis for rational inferences and reasonable speculation about the functional role in aquatic and terrestrial ecosystems. Recent identification of the biosynthetic genes for STX analogs in both cyanobacteria and dinoflagellates has yielded insights into biosynthetic mechanisms of toxin heterogeneity among strains and the evolutionary origins of their respective elements of the toxin gene clusters. Although it is not fully understood how or why these molecules are \u0000produced in nature, development of improved detection methods will make possible the discovery of new sources and analogs. Once genetic mechanisms for toxin biosynthesis are fully incorporated with modeling of receptor binding interactions and the structural–functional affinities of the ion channels, this will facilitate further biotechnological exploitation of these exquisite bioactive compounds and point the way toward future development of pharmaceuticals and therapeutic applications.","PeriodicalId":333390,"journal":{"name":"Blue Biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129702273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chitin of Poriferan Origin as a Unique Biological Material","authors":"H. Ehrlich","doi":"10.1002/9783527801718.CH26","DOIUrl":"https://doi.org/10.1002/9783527801718.CH26","url":null,"abstract":"","PeriodicalId":333390,"journal":{"name":"Blue Biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122298128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Peptide Antibiotics from Marine Microorganisms","authors":"N. Kasanah","doi":"10.1002/9783527801718.CH13","DOIUrl":"https://doi.org/10.1002/9783527801718.CH13","url":null,"abstract":"","PeriodicalId":333390,"journal":{"name":"Blue Biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134519507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How Fluorescent and Bioluminescent Proteins Have Changed Modern Science","authors":"M. Zimmer","doi":"10.1002/9783527801718.CH24","DOIUrl":"https://doi.org/10.1002/9783527801718.CH24","url":null,"abstract":"","PeriodicalId":333390,"journal":{"name":"Blue Biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130659270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microalgae: A Renewable Resource for Food and Fuels and More","authors":"S. Blackburn, K. Lee-Chang","doi":"10.1002/9783527801718.CH1","DOIUrl":"https://doi.org/10.1002/9783527801718.CH1","url":null,"abstract":"Microalgae are a large and diverse group of microscopic aquatic plants that are responsible for over half of the global primary productivity. They constitute a major food source for organisms at the base of the marine and other aquatic food webs and are important components of many ecosystems. Cultivation of microalgae offers a renewable resource for foods, fuels, aquaculture feeds, and other bioproducts and bioapplications. Bioproducts include a feedstock for biofuels and high-value lipids such as long-chain omega-3 oils, carotenoid pigments, and squalene, as well as other non-lipid materials, including exopolysaccharides. Successful commercial cultivation is dependent on the knowledge of the microalgal strain biology, matching the growth conditions according to the particular geographic sites and culturing and processing methods for the bioproducts of interest. Marine microalgae, as well as those from brackish and hypersaline environments, are grown in seawater at various salinities. Both autotrophic and heterotrophic cultivations are important, offering options in strain biology, chemistry, and production methods. Detailed fatty acid profiles demonstrate characterization of the microalgae into different chemotaxonomic groups, giving useful tools for identifying candidates with favorable bioproduct qualities for further optimization, for example, fast growth, high oil content, and suitable lipid composition. This chapter provides a perspective on the cultivation and qualities of microalgae for their renewable bioproduct and bioapplication potential, which offers great future potential in renewable marine resources. Blue Biotechnology: Production and Use of Marine Molecules, First Edition. Edited by Stéphane La Barre and Stephen S. Bates. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA. Published 2018 by Wiley-VCH Verlag GmbH & Co. KGaA. CO PY RI GH TE D M AT ER IA L 4 1 Microalgae: A Renewable Resource for Food and Fuels and More","PeriodicalId":333390,"journal":{"name":"Blue Biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116596466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}