The Journal of Multidisciplinary Research最新文献

{"title":"Pretreatment of lignocellulosic biomass for bioethanol production","authors":"Sonali Raj","doi":"10.37022/tjmdr.v4i2.582","DOIUrl":"https://doi.org/10.37022/tjmdr.v4i2.582","url":null,"abstract":"This review surveys recent progress in pretreatment methods for enhancing bioethanol production from lignocellulosic biomass. Various pretreatment techniques, including physical, chemical, and biological approaches, are evaluated for their efficacy in breaking down biomass structure and improving enzymatic digestibility. Key parameters influencing pretreatment effectiveness and integration with downstream processes are discussed. The review highlights promising strategies and identifies areas for further research to optimize bioethanol production from lignocellulosic feedstocks.","PeriodicalId":333297,"journal":{"name":"The Journal of Multidisciplinary Research","volume":" 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141128765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"THE Point prevalence of acetylcholinesterase inhibition, neuropathy and safety awareness among flower farm workers in naivasha, nakuru county, kenya.","authors":"S. Mathenge, Patroba Ojola, Hannah Wanjiru Mwangi","doi":"10.37022/tjmdr.v4i1.553","DOIUrl":"https://doi.org/10.37022/tjmdr.v4i1.553","url":null,"abstract":"Acetyl cholinesterase catalyses the hydrolysis of acetylcholine in the nerve synapses, thereby terminating nerve impulse, however, it is inhibited by organophosphates and carbamates. This study aimed to assess the level of acetyl cholinesterase inhibition and the resultant neuropathy in flower farm workers as well as the farmers’ awareness of safety measures and predisposing factors while handling pesticides. A cross-sectional study was conducted involving 217 participants from different flower farms. Structured questionnaire was used to collect data to assess level of safety and predisposing awareness and to assess for neuropathy. Blood samples were collected to determine the cholinesterase levels using spectrophotometry technique at 405 nm. The mean serum cholinesterase level in flower farm workers in Naivasha was 5873.26 U/L. There was a positive correlation (R= 0.07) between the numbers of years worked in the industry and serum cholinesterase levels as shown by Karl Pearson`s coefficient. The point prevalence of cholinesterase inhibition in Naivasha was 14% indicating a significant risk of adverse health effects. The level of safety awareness and predisposing factors among workers on pesticide exposure was 65%, suggesting that while the majority of workers had some level of safety awareness, there is still room for improvement. The point prevalence of neuropathy was 38% of the participants presenting with varying symptoms of adverse effects of pesticide exposure. Musculoskeletal impairment was leading at 19.81%, followed by skin irritation at 13.36%.These findings highlighted the need for better safety measures and awareness campaigns in the flower farm industry to reduce the risk of acetyl cholinesterase inhibition.","PeriodicalId":333297,"journal":{"name":"The Journal of Multidisciplinary Research","volume":"27 23","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140263965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Takotsubo cardiomyopathy (Broken heart syndrome)","authors":"Kalepu Manisha, Shruti Bhardwaj, Sri Alekhya S.V, Dhanyaswaroopa P, Rishitha Nallamelli, Randeep raj V.C","doi":"10.37022/tjmdr.v3i3.538","DOIUrl":"https://doi.org/10.37022/tjmdr.v3i3.538","url":null,"abstract":"Takotsubo cardiomyopathy or takotsubo syndrome (TTS), also known as stress cardiomyopathy, is a type of non-ischemic cardiomyopathy in which there is a sudden temporary weakening of the muscular portion of the heart. This condition is sometimes called “Broken Heart Syndrome”.it predominantly affects postmenopausal women, often triggered by acute emotional stressors, physical stressors, or a combination of both. The exact pathophysiological mechanisms remain incompletely elucidated. Diagnosis relies on clinical history, physical examination, ECG and cardiomyopathy from acute coronary syndrome is crucial for management.","PeriodicalId":333297,"journal":{"name":"The Journal of Multidisciplinary Research","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139235146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Usage and Effect of Social Media Networks on Students’ Academic Achievement in the Case of Assosa University","authors":"Cheru Haile Tesfay, Yimer Amedie, Biniyam Wondie, Abebe Senbeta, Yimenu Atinaf, Ashagerech Mekuria","doi":"10.37022/tjmdr.v3i3.494","DOIUrl":"https://doi.org/10.37022/tjmdr.v3i3.494","url":null,"abstract":"Social media network is a phenomenon of web application which has a new science of media network based on web-based service that gives individuals the opportunity to create either a public or group profile within a bounded system. It is so easy to use and does not need skill and professionalism to use it, cheap cost, and the introduction of smartphones leads to social media networks best to use in our daily lives. We can use Social media networks for different reasons in the community and the world. One of the main reasons is communication purpose between individuals aboard live at low cost is the primary advantage.  In addition to this, it adds a list of others' profiles to those who share a connection made by others within the system. Therefore, this study was carried out to examine the usage and effect of social media on students’ academic performance at Assosa University. This research adopted descriptive and explanatory research design. It also employed the use of a cross-sectional survey method using survey questionnaires that contained 20 items and focus group discussion. The sample of 382 students was selected from Assosa University using the Yemane sampling method. The data collected was analyzed using descriptive and chi-square(X2) inferential statistics via SPSS 21. Using the chi-square(X2) inferential statistics four variables are significant which include: exposure to social media, daily usage of the social media network, age, and health addiction while student relation and sex problems are not significant.","PeriodicalId":333297,"journal":{"name":"The Journal of Multidisciplinary Research","volume":"44 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139278799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Comparative Analyses for NRZ and RZ to the Best Performance in Optisystem Program to Cary Data Over Fiber Optics","authors":"H. J. Hasan","doi":"10.37022/tjmdr.v3i3.481","DOIUrl":"https://doi.org/10.37022/tjmdr.v3i3.481","url":null,"abstract":"Data transmission has become an important issue in today's telecommunications world. In order to get the best results in sending and receiving data via optical cable, there are various ways to improve the performance of such systems. In this paper, the simulation program (optsystem)was used to design a communication system for data transmission over a fiber optic to compare the performances of the Return to the Zero (RZ) as well as Non Return to the  Zero (NRZ) for different distances. The data was sent over distances ranging from 5 km to 50 km, with an increase of 5 km for each measurement. And recording the values of both Q. factor and (BER), as well as recording eye diagram figures for each case in order to compare to get the best performance for each distance used.","PeriodicalId":333297,"journal":{"name":"The Journal of Multidisciplinary Research","volume":"68 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139340839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Design, Formulation, and Evaluation of Risperidone Mucoadhesive Buccal Patches","authors":"Dr. Firoz Shaik, Likitha Kalimidi, Porkodi S, Chandana R, Tilak Arasan U","doi":"10.37022/tjmdr.v3i2.461","DOIUrl":"https://doi.org/10.37022/tjmdr.v3i2.461","url":null,"abstract":"Objectives: To construct and optimize Risperidone (RIS) mucoadhesive buccal films for systemic distribution as an alternate route. To make buccal patches of Risperidone utilizing natural polymers such sodium alginate (SA), Hydroxypropyl methylcellulose (HPMC), Na CMC, and Carbopol 934 (CP 934). Method: Solvent casting created Risperidone buccal patches. The optimization study used a software-based response surface methodology approach with 23 factorial designs to evaluate 8 formulations of Risperidone mucoadhesive buccal patches to determine the significant effect of selected independent variables on the dependent variable. To assess patch appearance, thickness, weight homogeneity, folding durability, medication content, surface pH, swelling index, and FTIR. Invitro dissolution, ex-vivo permeation, residence time, and stability tests. Results: FTIR and DSC showed that Risperidone was entirely entrapped in polymer carrier bonds with no chemical interaction. Drug distribution was uniform in buccal patches at 90.14± 0.07 and 98.75± 0.80. Conclusion: Buccal patch medicine release and penetration depended on polymer type. Hydrophilic polymers boosted buccal patch drug release. F6 was the best of F1–F8. Formulation F6 had 82.03 ±0.82% in-vitro drug release and 75.21 ± 0.42% ex-vivo permeability after 7 hours. Stability tests did not modify appearance, surface pH, content homogeneity, in-vitro residence length, medication release, or ex-vivo penetration.","PeriodicalId":333297,"journal":{"name":"The Journal of Multidisciplinary Research","volume":"139 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128135112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quick View on Bacterial translation analysis web tools","authors":"Venkata Sri Krishna Kona, Deepthi Sri Kanigiri, Mohammed Azharuddin, Lekha Arrolla","doi":"10.37022/tjmdr.v3i2.468","DOIUrl":"https://doi.org/10.37022/tjmdr.v3i2.468","url":null,"abstract":"Bacterial translation was learnt by researcher from the past four decades and significant data was generated. Inquisite to understand performance of the bacteria to produce a particular recombinant protein so as to pre-evaluate and make necessary modifications for optimal production is the key interest for researcher and biopharma manufacturers. Over a decade various databases were built and based on this valuable data webtools were developed which enable researcher to tweak the strategy beforehand. Here in this article we outlined various database and webtools based on protein translation which are currently being used. ","PeriodicalId":333297,"journal":{"name":"The Journal of Multidisciplinary Research","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133050213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A brief analysis of Article 368 and some important cases around it","authors":"Rutushree Sahu","doi":"10.37022/tjmdr.v3i2.463","DOIUrl":"https://doi.org/10.37022/tjmdr.v3i2.463","url":null,"abstract":"This paper discusses the relationship between the judiciary and the legislature in India. It argues that the judiciary has the power of judicial review, which allows it to strike down laws that it deems to be unconstitutional. This power has been used by the judiciary to balance the power of the legislature and to ensure that the rights of citizens are protected. The paper begins by discussing the history of judicial review in India. It then examines the two landmark cases in which the Supreme Court of India has upheld its power of judicial review: Kesavananda Bharati v. State of Kerala and Minerva Mills v. Union of India. The paper then discusses the implications of judicial review for the relationship between the judiciary and the legislature. The paper argues that judicial review is a necessary check on the power of the legislature. It also argues that judicial review can help to protect the rights of citizens. However, the paper also acknowledges that judicial review can be used to interfere with the democratic process. The paper concludes by arguing that the judiciary and the legislature should work together to ensure that the power of judicial review is used in a responsible way and focuses on the point that the legislature should be transparent about its decision-making process and that it should be accountable to the people.","PeriodicalId":333297,"journal":{"name":"The Journal of Multidisciplinary Research","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114939083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Wastewater Management Techniques: A Review","authors":"Dipak Puri, S. Yasmeen, Wanare Ashwini, Bharti Shubhangi","doi":"10.37022/tjmdr.v3i2.443","DOIUrl":"https://doi.org/10.37022/tjmdr.v3i2.443","url":null,"abstract":"The wastewater treatment research is based on industrial processes and agriculturalwastewater treatment methods. Most of the river basins are closed to severe water storages, brought on by the simultaneous effects of agricultural growth, industrialization and urbanization. In these research the aerobic, anaerobic or the combination of methods used. Other than that an adsorption and coagulation have been applied to remove the pollution. The research on chemical industrial wastewater treatment was first studied on organic removal efficiency of a lab scale system using aerobic and anaerobic reactors. The aerobic waste water treatment as a reductive medium is receiving increased interest due to its low operation and maintenance costs and aerobic waste water treatment is easy to obtain. The primary goal of the wastewater treatment process is to eliminate various pollutants such as solids, organic carbon, nutrients, inorganic salts, metals, pathogens and so on effective wastewater treatment and disposal are critical for both environmental and public health reasons. The aim of wastewater treatment is to protect the environment and waste water management. The many research papers on wastewater pollution control studies, but very few research works is carried out for treatment of wastewater. The beneficial aspect of this paper is recycling, reuse of water. The industrial wastewater is divided into four categories: Chemical, Physical, Biological and mathematical approaches. In this main focused on the Biological methods viz. Aerobic and an aerobic.","PeriodicalId":333297,"journal":{"name":"The Journal of Multidisciplinary Research","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129931725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development & determination of UV method for sildenafil & fluxetine in bulk drug & in formulation","authors":"Satya Prasad B, N. J, S. P, B. P, ChaitanyaKrishna R, Lakshmi Vasanthi T, Tirupati Rao Y, H. K","doi":"10.37022/tjmdr.v3i1.440","DOIUrl":"https://doi.org/10.37022/tjmdr.v3i1.440","url":null,"abstract":"A simple, rapid, precise and highly selective spectrophotometric method was developed for simultaneous estimation of Sildenafil citrate and Fluoxetine Hydrochloride in tablet dosage form. This method, involves the measurement of absorbances of Sildenafil citrate and Fluoxetine Hydrochloride at the wavelengths of 282nm (λmax of Sildenafil citrate) and 249 nm (λmax of Fluoxetine Hydrochloride). Methanol was used as solvent. Linearity was observed in the concentration range of 10-18µg/ml for Sildenafil citrate and 3-8ug/ml. Fluoxetine Hydrochloride. The accuracy of the method was confirmed by recovery studies of tablet dosage forms and was found to be 98.1% and 99.2% for Sildenafil citrate and Fluoxetine Hydrochloride respectively. The method showed good reproducibility and recovery with % RSD less than 2. Thus, the proposed method was found to be rapid, specific, precise, accurate and cost-effective quality control tool for the routine analysis of Sildenafil citrate and Fluoxetine Hydrochloride in bulk and combined dosage form. A rapid and simple derivative spectrophotometric method was developed for simultaneous determination of Sildenafil citrate and Fluoxetine Hydrochloride in tablet dosage form. This method involves second order derivative spectroscopy using 282 nm and 249 nm as zero crossing points for Sildenafil citrate and Fluoxetine Hydrochloride respectively in methanol. Linearity was observed in the concentration range of 10-18µg/ml for Sildenafil citrate and 3-8ug/ml for Fluoxetine Hydrochloride. The accuracy of the method was found to be 98.21% and 99.2% for Sildenafil citrate and Fluoxetine Hydrochloride respectively. The method showed good reproducibility and recovery with % RSD less than 2.Thus, the proposed method was found to be rapid, specific, precise, accurate and cost-effective quality control tool for the routine analysis of sildenafil citrate and Fluoxetine Hydrochloride in bulk and combined dosage form.                A selective, precise, isocratic and accurate stability indicating reverse phase high performance liquid chromatographic method was developed for the simultaneous determination of Sildenafil citrate and Fluoxetine Hydrochloride in the tablet dosage form. The method was validated for the linearity, accuracy, precision, robustness, system suitability as per ICH guidelines. Sildenafil citrate and Fluoxetine Hydrochloride were found to be linear in the range of 10-100 and 10-18µg/ml and 3-8ug/ml with the recoveries of 98.6% and 99.2%. The method was also applied for the determination of sildenafil citrate and Fluoxetine Hydrochloride in the presence of their degradation products formed under variety of stress conditions.","PeriodicalId":333297,"journal":{"name":"The Journal of Multidisciplinary Research","volume":"143 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129785364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}