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TumorDiagnostik & Therapie最新文献

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Intravesikales Gemcitabin-Abgabesystem beim muskelinvasiven Blasenkarzinom 治疗肌肉浸润性膀胱癌的膀胱内吉西他滨给药系统
TumorDiagnostik & Therapie Pub Date : 2024-03-01 DOI: 10.1055/a-2253-1472
{"title":"Intravesikales Gemcitabin-Abgabesystem beim muskelinvasiven Blasenkarzinom","authors":"","doi":"10.1055/a-2253-1472","DOIUrl":"https://doi.org/10.1055/a-2253-1472","url":null,"abstract":"","PeriodicalId":333101,"journal":{"name":"TumorDiagnostik & Therapie","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140276120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prostatakrebs: Neu entwickelter Hemmstoff zeigt großes Potenzial 前列腺癌：新开发的抑制剂显示出巨大潜力
TumorDiagnostik & Therapie Pub Date : 2024-03-01 DOI: 10.1055/a-2189-6656
{"title":"Prostatakrebs: Neu entwickelter Hemmstoff zeigt großes Potenzial","authors":"","doi":"10.1055/a-2189-6656","DOIUrl":"https://doi.org/10.1055/a-2189-6656","url":null,"abstract":"","PeriodicalId":333101,"journal":{"name":"TumorDiagnostik & Therapie","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140274670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neue Therapiestrategien beim HER2-positiven metastasierten Mammakarzinom HER2 阳性转移性乳腺癌的新治疗策略
TumorDiagnostik & Therapie Pub Date : 2024-03-01 DOI: 10.1055/a-2253-1323
{"title":"Neue Therapiestrategien beim HER2-positiven metastasierten Mammakarzinom","authors":"","doi":"10.1055/a-2253-1323","DOIUrl":"https://doi.org/10.1055/a-2253-1323","url":null,"abstract":"","PeriodicalId":333101,"journal":{"name":"TumorDiagnostik & Therapie","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140278997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Urothelkarzinom des oberen Harntrakts: Detektion anhand von Urinproben möglich 上尿路尿路上皮癌：利用尿液样本进行检测的可能性
TumorDiagnostik & Therapie Pub Date : 2024-03-01 DOI: 10.1055/a-2253-1453
{"title":"Urothelkarzinom des oberen Harntrakts: Detektion anhand von Urinproben möglich","authors":"","doi":"10.1055/a-2253-1453","DOIUrl":"https://doi.org/10.1055/a-2253-1453","url":null,"abstract":"","PeriodicalId":333101,"journal":{"name":"TumorDiagnostik & Therapie","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140084677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
ABDOMEN BECKEN – Vollständige Nekrosen nach lokoregionaler Therapie hepatozellulärer Karzinome ABDOMEN BECKEN - 肝细胞癌局部治疗后完全坏死
TumorDiagnostik & Therapie Pub Date : 2024-03-01 DOI: 10.1055/a-2253-1598
{"title":"ABDOMEN BECKEN – Vollständige Nekrosen nach lokoregionaler Therapie hepatozellulärer Karzinome","authors":"","doi":"10.1055/a-2253-1598","DOIUrl":"https://doi.org/10.1055/a-2253-1598","url":null,"abstract":"","PeriodicalId":333101,"journal":{"name":"TumorDiagnostik & Therapie","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140087935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adagrasib bei KRAS-G12C-mutierten kolorektalen Karzinomen effektiv Adagrasib 对 KRAS-G12C 突变的结直肠癌有效
TumorDiagnostik & Therapie Pub Date : 2024-03-01 DOI: 10.1055/a-2253-1549
{"title":"Adagrasib bei KRAS-G12C-mutierten kolorektalen Karzinomen effektiv","authors":"","doi":"10.1055/a-2253-1549","DOIUrl":"https://doi.org/10.1055/a-2253-1549","url":null,"abstract":"","PeriodicalId":333101,"journal":{"name":"TumorDiagnostik & Therapie","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140269216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Blasenerhaltende multimodale Therapiekonzepte 保留膀胱的多模式疗法概念
TumorDiagnostik & Therapie Pub Date : 2024-03-01 DOI: 10.1055/a-1980-7937
Oliver J. Ott
{"title":"Blasenerhaltende multimodale Therapiekonzepte","authors":"Oliver J. Ott","doi":"10.1055/a-1980-7937","DOIUrl":"https://doi.org/10.1055/a-1980-7937","url":null,"abstract":"","PeriodicalId":333101,"journal":{"name":"TumorDiagnostik & Therapie","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140276663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
RANK and RANKL Expression in Tumors of Patients with Early Breast Cancer 早期乳腺癌患者肿瘤中的 RANK 和 RANKL 表达
TumorDiagnostik & Therapie Pub Date : 2024-03-01 DOI: 10.1055/a-2257-9565
Annika S Behrens, Lena Wurmthaler, F. Heindl, Paul Gass, Lothar Häberle, B. Volz, C. Hack, Julius Emons, R. Erber, A. Hartmann, Matthias W. Beckmann, M. Ruebner, W. Dougall, Peter A. Fasching, H. Huebner, Michael F. Press
{"title":"RANK and RANKL Expression in Tumors of Patients with Early Breast Cancer","authors":"Annika S Behrens, Lena Wurmthaler, F. Heindl, Paul Gass, Lothar Häberle, B. Volz, C. Hack, Julius Emons, R. Erber, A. Hartmann, Matthias W. Beckmann, M. Ruebner, W. Dougall, Peter A. Fasching, H. Huebner, Michael F. Press","doi":"10.1055/a-2257-9565","DOIUrl":"https://doi.org/10.1055/a-2257-9565","url":null,"abstract":"The receptor activator of nuclear factor-κB (RANK) pathway was associated with the pathogenesis of breast cancer. Several studies attempted to link the RANK/RANKL pathway to prognosis;\u0000 however, with inconsistent outcomes. We aimed to further contribute to the knowledge about RANK/RANKL as prognostic factors in breast cancer. Within this study, protein expression of RANK and\u0000 its ligand, RANKL, in the tumor tissue was analyzed in association with disease-free survival (DFS) and overall survival (OS) in a study cohort of patients with early breast cancer.607 samples of female primary and early breast cancer patients from the Bavarian Breast Cancer Cases and Controls Study were analyzed to correlate the RANK and RANKL expression with DFS\u0000 and OS. Therefore, expression was quantified using immunohistochemical staining of a tissue microarray. H-scores were determined with the cut-off value of 8.5 for RANK and 0 for RANKL\u0000 expression, respectively.RANK and RANKL immunohistochemistry were assessed by H-score. Both biomarkers did not correlate (ρ = −0.04). According to molecular subtypes, triple-negative tumors and HER2-positive\u0000 tumors showed a higher number of RANK-positive tumors (H-score ≥ 8.5), however, no subtype-specific expression of RANKL could be detected. Higher RANKL expression tended to correlate with a\u0000 better prognosis. However, RANK and RANKL expression could not be identified as statistically significant prognostic factors within the study cohort.Tumor-specific RANK and RANKL expressions are not applicable as prognostic factors for DFS and OS, but might be associated with subtype-specific breast cancer progression.","PeriodicalId":333101,"journal":{"name":"TumorDiagnostik & Therapie","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140279326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Thrombotische Mikroangiopathie 血栓性微血管病
TumorDiagnostik & Therapie Pub Date : 2024-03-01 DOI: 10.1055/a-2241-8761
R. Wendt
{"title":"Thrombotische Mikroangiopathie","authors":"R. Wendt","doi":"10.1055/a-2241-8761","DOIUrl":"https://doi.org/10.1055/a-2241-8761","url":null,"abstract":"","PeriodicalId":333101,"journal":{"name":"TumorDiagnostik & Therapie","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140281420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Muzinöses Ovarialkarzinom: Prognose des expansilen und des infiltrativen Subtyps 粘液性卵巢癌：扩张亚型和浸润亚型的预后
TumorDiagnostik & Therapie Pub Date : 2024-03-01 DOI: 10.1055/a-2253-1520
{"title":"Muzinöses Ovarialkarzinom: Prognose des expansilen und des infiltrativen Subtyps","authors":"","doi":"10.1055/a-2253-1520","DOIUrl":"https://doi.org/10.1055/a-2253-1520","url":null,"abstract":"","PeriodicalId":333101,"journal":{"name":"TumorDiagnostik & Therapie","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140272013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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