Journal of Acupuncture Research最新文献_第6页

Astaxanthin Ameliorates Atopic Dermatitis by Inhibiting the Expression of Signal Molecule NF-kB and Inflammatory Genes in Mice 虾青素通过抑制小鼠信号分子NF-kB和炎症基因的表达改善特应性皮炎

Journal of Acupuncture Research Pub Date : 2022-11-30 DOI: 10.13045/jar.2022.00255

Donghwan Kim, Yong-Suk Kim, H. Song

{"title":"Astaxanthin Ameliorates Atopic Dermatitis by Inhibiting the Expression of Signal Molecule NF-kB and Inflammatory Genes in Mice","authors":"Donghwan Kim, Yong-Suk Kim, H. Song","doi":"10.13045/jar.2022.00255","DOIUrl":"https://doi.org/10.13045/jar.2022.00255","url":null,"abstract":"Background: This study was conducted to determine the anti-inflammatory effect of astaxanthin, on atopic dermatitis.Methods: Changes in mouse body weight, lymph node weight, and the degree of improvement in symptoms were measured to determine the inflammatory response. Real-time reverse transcription-polymerase chain reaction tests were performed to determine the degree of expression of inflammation-related cytokines (IL-31 and IL-33 and chemokines such as CCL17 and CCL22), and western blot analysis was performed to evaluate the expression of inflammation-related factors (iNOS, COX-2, and NF-kB signaling molecules p-IkBα, p50, p-65 and pSTAT3).Results: The degree of symptoms significantly improved in the PA+AX group. Lymph node weight in the PA+AX group was lower than the PA group. Inflammatory cytokines (IL-31, IL-33, and inflammatory chemokines such as CCL17 and CCL22) were significantly reduced in the PA+AX group compared with the PA group. The expression of inflammatory genes (iNOS, COX-2, NF-kB and signaling molecules (p-IkBα, p50, p65, and p-STAT 3) was lower in the PA+AX group compared with the PA group.Conclusion: Astaxanthin may modulate the inflammatory response in a mouse model of atopic dermatitis and has an anti-inflammatory effect.","PeriodicalId":33306,"journal":{"name":"Journal of Acupuncture Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49079976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

A Literature Review of Randomized Controlled Trials on Tobacco Cessation Using Auricular Acupuncture and Auricular Acupressure 耳针与耳压戒烟随机对照试验文献综述

Journal of Acupuncture Research Pub Date : 2022-11-30 DOI: 10.13045/jar.2022.00185

Min-Gi Jo, Jun-Yeong Jang, Minkailov Ko, S. Chae, Seungeun Lee, Dongmin Lee, Won-Suk Sung, Jung-hyun Kim, Bonhyuk Goo, Yeoncheol Park, Y. Baek, Sang-Soo Nam, B. Seo

引用次数: 0

The Risk of Applying Moving Cupping Therapy to A Patient with Chronic Lumbar Pain Previously Treated with Gold Thread Therapy 对曾接受金线疗法治疗的慢性腰痛患者应用走罐疗法的风险分析

Journal of Acupuncture Research Pub Date : 2022-11-30 DOI: 10.13045/jar.2022.00192

Yeo-Gab Kim, Yoona Oh, Jihun Kim, Eunseok Kim, G. Yang, Byung-Ryul Lee

引用次数: 1

A Study on the Significance of Acupuncture and Pharmacopuncture Therapy for Cold Accumulation Through a Literature Review on the Historical Development Process in Cold Accumulation Treatment 通过对寒积治疗历史发展过程的文献回顾，探讨针药治疗寒积的意义

Journal of Acupuncture Research Pub Date : 2022-11-30 DOI: 10.13045/jar.2022.00178

Jin-Ho Jeong, Jaseung Ku, Ji-hye Hwang

{"title":"A Study on the Significance of Acupuncture and Pharmacopuncture Therapy for Cold Accumulation Through a Literature Review on the Historical Development Process in Cold Accumulation Treatment","authors":"Jin-Ho Jeong, Jaseung Ku, Ji-hye Hwang","doi":"10.13045/jar.2022.00178","DOIUrl":"https://doi.org/10.13045/jar.2022.00178","url":null,"abstract":"In order to secure clinical evidence for the treatment of cold accumulation (CA), this study reviewed and analyzed 91 records of literature and related records. To perform a classical literature search, the Oriental Medicine Classic databases and the Uibujeonrok electronic data were searched. Books on Immuno-pharmacopuncture (IP) were also reviewed. A common etiology for CA was attributed to the abdomen, while the detailed sites of the abdomen differed. In IP, CA had a more comprehensive list of symptoms of physiological and pathological significance. As for the treatment of CA, typically, herbal medicine was used until the end of the Korean Empire period, and moxibustion treatment on CV4, CV6, CV-12, ST36, EX-B4, and conduction exercise therapy were also reported. Since 1965, acupuncture needle-based invasive treatment such as acupuncture for CA, and IP have been described in IP theory. Consequently, the treatment of CA (as described in the IP theory), was considered to be a more advanced method of treatment compared with the existing classical treatment methods.","PeriodicalId":33306,"journal":{"name":"Journal of Acupuncture Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43384948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

The Evaluation of the Acute Toxicity and Safety of Verbenalin in ICR Mice 维拉那林对ICR小鼠急性毒性及安全性的评价

Journal of Acupuncture Research Pub Date : 2022-11-30 DOI: 10.13045/jar.2022.00248

Hyejeong Shin, Y. Lim, Jisu Ha, Gabsik Yang, T. Yook

{"title":"The Evaluation of the Acute Toxicity and Safety of Verbenalin in ICR Mice","authors":"Hyejeong Shin, Y. Lim, Jisu Ha, Gabsik Yang, T. Yook","doi":"10.13045/jar.2022.00248","DOIUrl":"https://doi.org/10.13045/jar.2022.00248","url":null,"abstract":"Background: Verbenalin is an iridoid glucoside, which is among the active components of some medicinal herbs such as Verbena officinalis Linn, and Cornus officinalis Siebold and Zucc. Previous studies have confirmed the antioxidant activity and neuroprotective potential of verbenalin. To confirm the safety of verbenalin, an approximate lethal dose was determined based on a single oral dose toxicity study.Methods: Institute of Cancer Research mice were randomly assigned to three verbenalin exposure groups (250, 500, and 1,000 mg/kg) and a control group (5% methylcellulose solution). There were (5 male and 5 female mice per group). Mortality, clinical signs, and body weight were monitored for 14 days, and necropsies were conducted.Results: No mortalities were observed in the control group or the verbenalin 250 mg/kg group, whereas mortalities were observed in the 500 mg/kg and 1,000 mg/kg verbenalin groups. During the observation period, stool abnormalities such as mucous stools were observed. Clinical signs such as loss of locomotor activity were observed in the 500 mg/kg and 1,000 mg/kg verbenalin groups. During the study period, significant changes in body weight were observed in the 500 mg/kg and 1,000 mg/kg verbenalin groups; however, no gross abnormalities were observed at necropsy. Overall, no toxicity was found in the 250 mg/kg group.Conclusion: The approximate lethal dose of verbenalin was estimated to be 500 mg/kg. For a more accurate assessment of the safety of verbenalin, other types of studies such as repeated-dose toxicity studies should also be conducted.","PeriodicalId":33306,"journal":{"name":"Journal of Acupuncture Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47953288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acupuncture for Adult Obstructive Sleep Apnea or Obstructive Sleep Apnea-Hypopnea Syndrome: A Review of the China National Knowledge Infrastructure Database 针刺治疗成人阻塞性睡眠呼吸暂停或阻塞性睡眠呼吸暂停低通气综合征:中国国家知识基础数据库综述

Journal of Acupuncture Research Pub Date : 2022-11-30 DOI: 10.13045/jar.2022.00206

Hye-kyung Baek, Young Jun Kim, Y. Lee, H. Jo, Mi-so Park, Dong-guk Shin, Hyun A Shim

{"title":"Acupuncture for Adult Obstructive Sleep Apnea or Obstructive Sleep Apnea-Hypopnea Syndrome: A Review of the China National Knowledge Infrastructure Database","authors":"Hye-kyung Baek, Young Jun Kim, Y. Lee, H. Jo, Mi-so Park, Dong-guk Shin, Hyun A Shim","doi":"10.13045/jar.2022.00206","DOIUrl":"https://doi.org/10.13045/jar.2022.00206","url":null,"abstract":"The purpose of this study was to analyze acupuncture treatment methods and acupoints used to treat obstructive sleep apnea (OSA) or obstructive sleep apnea-hypoapnea syndrome (OSAHS). The data were retrieved from January 2010 to May 2022 from the China National Knowledge Infrastructure database. The search terms included “adult,” “obstructive sleep apnea,” “obstructive sleep apnea hypoapnea syndrome,” “acupuncture,” and “electro-acupuncture.” Clinical trials for acupuncture treatment of OSA or OSAHS were included in this review (4 non-randomized controlled studies, 1 was a case report, and 10 randomized controlled studies). For OSA and OSAHS treatment, the acupoints that were most frequently used included REN23, LU7, ST40, EX9, LI11, and DU20. Compared with the control or Western treatment group, the treatment outcome measures of participants in the acupuncture treatment group significantly improved. In some studies, participants in the acupuncture group did not have side effects and the treatment was cost-effective. The data analyzed in this review suggest that acupuncture is an effective treatment for OSA or OSAHS.","PeriodicalId":33306,"journal":{"name":"Journal of Acupuncture Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46540431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Review of Rat Models of Avascular Necrosis of the Femoral Head Treated with Natural Extracts 天然提取物治疗大鼠股骨头缺血性坏死模型的研究进展

Journal of Acupuncture Research Pub Date : 2022-11-30 DOI: 10.13045/jar.2022.00227

Go-Woon Kim, Hyoung-Yong Park, Yeoncheol Park

{"title":"A Review of Rat Models of Avascular Necrosis of the Femoral Head Treated with Natural Extracts","authors":"Go-Woon Kim, Hyoung-Yong Park, Yeoncheol Park","doi":"10.13045/jar.2022.00227","DOIUrl":"https://doi.org/10.13045/jar.2022.00227","url":null,"abstract":"To determine the effect of Korean medicine treatment of avascular necrosis of the femoral head (ANFH) this study reviewed both single ingredients and bioactive compounds in the treatment of ANFH in a rat model. Literature was retrieved from PubMed and Google Scholar using the keywords “femur head necrosis,” “natural extract,” and “rat.” The data from studies analyzed included: rats’ characteristics, development methods of ANFH, natural extracts administration, observation methods, and outcome indicators. Two independent researchers screened all articles retrieved and 26 studies were chosen. The most used rat species was the Sprague Dawley rat (76.9%). To induce ANFH, steroid injections (46.2%), and oral gavage (53.8%) were typically used. Studies focused mainly on factors affecting bone formation (65.3%), and apoptosis (53.8%). Research on ANFH focused on using traditional natural substances mentioned in classical literature to confirm its effectiveness against anti-inflammation, osteogenesis, and cell death. ANFH has a diverse etiology, therefore research models such as genetic analysis of human-derived samples from ANFH patients may shed more light on the condition. Moreover, research into herbal medicines and pharmacoacupuncture treatment of ANFH should precede.","PeriodicalId":33306,"journal":{"name":"Journal of Acupuncture Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46812918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Quality Assessment of Clinical Practice Guidelines for Ankle Sprains Using the Appraisal of Guidelines for Research and Evaluation II Assessment Tool 使用研究和评估指南II评估工具评估踝关节扭伤临床实践指南的质量

Journal of Acupuncture Research Pub Date : 2022-11-30 DOI: 10.13045/jar.2022.00213

Jun-Yeong Jang, Min-Gi Jo, Minkailov Ko, S. Chae, Seungeun Lee, Dongmin Lee, Jung-hyun Kim, Bonhyuk Goo, B. Seo, Y. Baek, Sang-Soo Nam, Yeoncheol Park

引用次数: 0

Electroacupuncture Treatment for Primary Dysmenorrhea: A Review of Randomized Controlled Trials 电针治疗原发性痛经:随机对照试验综述

Journal of Acupuncture Research Pub Date : 2022-08-31 DOI: 10.13045/jar.2022.00164

M. Jeon, J. Park, M. Lee, H. Kim, J. Ahn, N. Shin, H. Nam, Go-Eun Chae, Hyemi Jo, Hyun Woo Kim, Young Jin Lee, Arha Koh, Woo Young Kim

{"title":"Electroacupuncture Treatment for Primary Dysmenorrhea: A Review of Randomized Controlled Trials","authors":"M. Jeon, J. Park, M. Lee, H. Kim, J. Ahn, N. Shin, H. Nam, Go-Eun Chae, Hyemi Jo, Hyun Woo Kim, Young Jin Lee, Arha Koh, Woo Young Kim","doi":"10.13045/jar.2022.00164","DOIUrl":"https://doi.org/10.13045/jar.2022.00164","url":null,"abstract":"To evaluate the effectiveness of electroacupuncture treatment for primary dysmenorrhea (PD), a literature review of a randomized controlled trials (RCTs) was performed where electroacupuncture was used as a treatment intervention in patients diagnosed with PD. Relevant clinical studies (N = 226) were retrieved from multiple databases according to the study inclusion/exclusion criteria, and interventions and outcomes were analyzed. As a result of the review, there were 6 RCTs which met the criteria. In all 4 studies that measured pain indicators (visual analog scales), electroacupuncture showed significantly positive changes. In addition, positive changes were observed in most indicators (MMDQ, PGF2a, PGE2, 6-keto PGF1, TXB2, clinical efficacy score, uterine arterial blood flow parameters, and blood viscosity). 2 studies showed that electroacupuncture had a stronger therapeutic effect than NSAIDs. No major side effects were reported. Electroacupuncture may be an effective and safe treatment for PD however, further RCTs are required.","PeriodicalId":33306,"journal":{"name":"Journal of Acupuncture Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44747842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effects of Korean Medicine Treatment for Meniscus Tears: A Retrospective Chart Review 韩药治疗半月板撕裂的疗效:回顾性图表回顾

Journal of Acupuncture Research Pub Date : 2022-08-31 DOI: 10.13045/jar.2022.00066

Ji-won Park, Myung-In Jeong, Wu-Jin Jeong, Hae-Won Hong, Ji-eun Koo, Jun-Hyo Bae, Su-jin Kim, Ji-eun Bae

{"title":"The Effects of Korean Medicine Treatment for Meniscus Tears: A Retrospective Chart Review","authors":"Ji-won Park, Myung-In Jeong, Wu-Jin Jeong, Hae-Won Hong, Ji-eun Koo, Jun-Hyo Bae, Su-jin Kim, Ji-eun Bae","doi":"10.13045/jar.2022.00066","DOIUrl":"https://doi.org/10.13045/jar.2022.00066","url":null,"abstract":"Changes in symptoms and dysfunction related to meniscus tears following the use of Korean medicine for ≥ 4 days were studied. The medical charts of 53 cases of diagnosed meniscus tears (magnetic resonance imaging) with an admission Numeric Rating Scale (NRS) score ≥ 4, between 2017 and 2022 were retrospectively reviewed. Treatments included acupuncture, pharmacopuncture, herbal treatment, Chuna therapy, and physiotherapy. The NRS, Western Ontario and McMaster Universities Osteoarthritis Index, and European Quality of Life 5 Dimensions were performed at admission and discharge. There were 42 females and 11 males in this study. Patients were more likely to be in their 60s (38.18%), have an unknown etiology (81.13%), and have complex tears (50.94%). After receiving a combination of alternative Korean medicine during hospitalization, the mean NRS score improved from 6.82 ± 1.19 to 3.66 ± 1.83 (p < 0.001), the Western Ontario and McMaster Universities Osteoarthritis Index score improved from 46.47 ± 20.99 to 37.98 ± 19.23 (p < 0.001), and the mean European Quality of Life Five Dimensions score improved from 0.61 ± 0.18 to 0.68 ± 0.14 (p < 0.001) after treatment. These results suggest that Korean medicine treatment of meniscus tears alleviated pain and improved physical function.","PeriodicalId":33306,"journal":{"name":"Journal of Acupuncture Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48826278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0