Journal of Neurocritical Care最新文献_第6页

Successful treatment with rituximab in a patient with lupus cerebritis and posterior reversible encephalopathy syndrome: a case report 利妥昔单抗治疗狼疮性脑炎合并后部可逆性脑病综合征1例

Journal of Neurocritical Care Pub Date : 2021-12-24 DOI: 10.18700/jnc.210028

Saemi Choi, Young Seo Kim

引用次数: 1

Serial brain magnetic resonance imaging in a patient with invasive streptococcal infection with ventriculitis and choroid plexitis 侵袭性链球菌感染合并脑室炎和脉络膜丛炎患者的连续脑磁共振成像分析

Journal of Neurocritical Care Pub Date : 2021-12-20 DOI: 10.18700/jnc.210026

Jaewoon Chung, Ji Young Lee, Young Seo Kim

{"title":"Serial brain magnetic resonance imaging in a patient with invasive streptococcal infection with ventriculitis and choroid plexitis","authors":"Jaewoon Chung, Ji Young Lee, Young Seo Kim","doi":"10.18700/jnc.210026","DOIUrl":"https://doi.org/10.18700/jnc.210026","url":null,"abstract":"ver, myalgia, and vomiting. His systolic blood pressure was below 60 mmHg, and he was admitted to the intensive care unit with the suspicion of septic shock. After admission, Streptococcus pneumonia was found in his blood, and treatment with vancomycin 2 g/day and ceftriaxone 4 g/day was initiated. Following antibiotic treatment for 4 days, his mentation deteriorated to a stupor. Brain magnetic resonance imaging (MRI) indicated hydrocephalus, ventriculitis, and choroid plexitis (Fig. 1). Cerebrospinal fluid (CSF) examination showed normal opening pressure (180 mmHg), pleocytosis (white blood cell count, 280; neutrophils, 55%), high protein level (1,448 mg/dL), and low glucose levels (CSF, 54 mg/dL; serum, 135 mg/dL). Consequently, a high dose of steroids (dexamethasone, 40 mg/day) was prescribed together with antibiotics. After 14 days of antibiotic treatment, his general condition improved. Brain MRI findings depicting pyogenic ventriculitis typically include ependymal thickening and enhancement with T2 prolongation surrounding the ventricle, hydrocephalus, and debris within the dependent aspect of the ventricles [1,2]. In addition, diffusion restriction and swelling of the choroid plexus are suggestive Serial brain magnetic resonance imaging in a patient with invasive streptococcal infection with ventriculitis and choroid plexitis Jaewoon Chung, MD; Ji Young Lee, MD, PhD; Young Seo Kim, MD, PhD Department of Neurology, Hanyang University College of Medicine, Seoul, Korea Department of Radiology, Hanyang University College of Medicine, Seoul, Korea Received: October 11, 2021 Revised: November 26, 2021 Accepted: November 26, 2021","PeriodicalId":33246,"journal":{"name":"Journal of Neurocritical Care","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41691864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Basic considerations on magnesium in the management of neurocritical patients 镁在神经危重症患者治疗中的基本考虑

Journal of Neurocritical Care Pub Date : 2021-11-15 DOI: 10.18700/jnc.210018

I. Lozada‐Martínez, Teddy Javier Padilla-Durán, Jhon Jairo González-Monterroza, Daniel Alfonso Aguilar-Espinosa, K. Molina-Perea, William Camargo-Martínez, Luz Katica Llamas-Medrano, Mariana Hurtado-Pinillos, Alejandra Guerrero-Mejía, Tariq Janjua, L. Moscote-Salazar

{"title":"Basic considerations on magnesium in the management of neurocritical patients","authors":"I. Lozada‐Martínez, Teddy Javier Padilla-Durán, Jhon Jairo González-Monterroza, Daniel Alfonso Aguilar-Espinosa, K. Molina-Perea, William Camargo-Martínez, Luz Katica Llamas-Medrano, Mariana Hurtado-Pinillos, Alejandra Guerrero-Mejía, Tariq Janjua, L. Moscote-Salazar","doi":"10.18700/jnc.210018","DOIUrl":"https://doi.org/10.18700/jnc.210018","url":null,"abstract":"Magnesium (Mg) is a chemical element that is essential for human life. In the brain, it is physiologically responsible for many processes involved in intracellular homeostasis, blood-brain barrier integrity, protein synthesis, neuronal proliferation, aging, and apoptosis [1]. This element is also a special target of research and Basic considerations on magnesium in the management of neurocritical patients Ivan David Lozada-Martinez, MS; Teddy Javier Padilla-Durán, MD; Jhon Jairo González-Monterroza, MD; Daniel Alfonso Aguilar-Espinosa, MD; Kelly Nathalia Molina-Perea, MD; William Camargo-Martinez, MS; Luz Llamas-Medrano, MS; Mariana Hurtado-Pinillos, MS; Alejandra Guerrero-Mejía, MD; Tariq Janjua, MD; Luis Rafael Moscote-Salazar, MD, PhD(c) Medical and Surgical Research Center, Cartagena, Colombia Colombian Clinical Research Group in Neurocritical Care, School of Medicine, University of Cartagena, Cartagena, Colombia Latin American Council of Neurocritical Care, Cartagena, Colombia School of Medicine, Universidad del Magdalena, Santa Marta, Colombia School of Medicine, Universidad de la Sabana, Chía, Colombia School of Medicine, Fundación Universitaria Juan N Corpas, Bogotá, Colombia Colombian Clinical Research Group in Neurocritical Care, School of Medicine, Fundación Universitaria Autonoma de las Americas, Pereira, Colombia School of Medicine, Universidad de Manizales, Manizales, Colombia Department of Intensive Care, Regions Hospital, St Paul, MN, USA REVIEW ARTICLE","PeriodicalId":33246,"journal":{"name":"Journal of Neurocritical Care","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43721748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Flaccid quadriparesis with raised creatine kinase in Guillain-Barré syndrome: a case report with review of literature 格林-巴-罗综合征伴肌酸激酶升高的弛缓性四肢瘫1例并文献复习

Journal of Neurocritical Care Pub Date : 2021-11-15 DOI: 10.18700/jnc.210011

B. Mahesh, A. Pathak, R. Chaurasia, Anand B Kumar, V. K. Singh

引用次数: 0

Brain injury in extracorporeal cardiopulmonary resuscitation: translational to clinical research 体外心肺复苏中的脑损伤:转化为临床研究

Journal of Neurocritical Care Pub Date : 2021-08-18 DOI: 10.18700/JNC.210016

C. Wilcox, C. Choi, Sung-Min Cho

引用次数: 7

Delayed cerebral infarction due to cerebral venous air emboli after cardiac arrest 心脏骤停后脑静脉空气栓塞致迟发性脑梗死

Journal of Neurocritical Care Pub Date : 2021-06-25 DOI: 10.18700/jnc.210012

Yoon-Kyung Lee, Jin-Heon Jeong

{"title":"Delayed cerebral infarction due to cerebral venous air emboli after cardiac arrest","authors":"Yoon-Kyung Lee, Jin-Heon Jeong","doi":"10.18700/jnc.210012","DOIUrl":"https://doi.org/10.18700/jnc.210012","url":null,"abstract":"ing tooth scaling. After 4 minutes, the return of spontaneous circulation (ROSC) was achieved. She was stuporose, but other neurological examinations were within normal limits. The patient had a history of meningitis, and she had undergone ventriculoperitoneal shunt surgery for hydrocephalus in her 20s. Brain computed tomography performed immediately after ROSC showed cerebral air emboli (Fig. 1A). Brain magnetic resonance imaging (MRI) after 5 hours showed no acute lesions (Fig. 1B). Targeted temperature management was performed. Her consciousness improved to a drowsy state, but left hemiparesis was observed. Brain MRI performed on the 6th day showed gyriform infarction in both frontoparietal cortices that were consistent with air emboli (Fig. 1C-E). Cerebral air embolism can lead to arterial and venous infarctions [1,2]. They can lead to blood flow obstruction and induce an inflammatory reaction with the breakdown of the blood-brain barrier [3]. In this case, the delayed cerebral infarction was detected by follow-up brain imaging. Cerebral venous air emboli can cause delayed cerebral infarction because the collateral circulation in the cerebral venous system allows for compensation. Even if the Delayed cerebral infarction due to cerebral venous air emboli after cardiac arrest Yoon-Kyung Lee, MD; Jin-Heon Jeong, MD Department of Neurology, Stroke Center, Dong-A University Hospital, Busan, Republic of Korea Department of Intensive Care Medicine, Dong-A University Hospital, Busan, Republic of Korea IMAGES IN NEUROCRITICAL CARE","PeriodicalId":33246,"journal":{"name":"Journal of Neurocritical Care","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43424471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Radiculopathy caused by lumbar epidural varix 腰椎硬膜外静脉曲张所致神经根病

Journal of Neurocritical Care Pub Date : 2020-12-29 DOI: 10.18700/jnc.200029

Ji-Na Shin, Nawon Oh, J. Huh, C. Hyun, Joong-Goo Kim, Sa-Yoon Kang, J. Oh

引用次数: 1

Blood pressure management in stroke patients 脑卒中患者的血压管理

Journal of Neurocritical Care Pub Date : 2020-12-29 DOI: 10.18700/jnc.200028

S. M. Kim, H. Woo, Y. Kim, B. Kim

引用次数: 7

The good genotype for clopidogrel metabolism is associated with decreased blood viscosity in clopidogrel-treated ischemic stroke patients 氯吡格雷代谢良好的基因型与氯吡格雷治疗的缺血性脑卒中患者的血液粘度降低有关

Journal of Neurocritical Care Pub Date : 2020-12-29 DOI: 10.18700/jnc.200023

J. Park, S. Han, Hyun-jeung Yu

{"title":"The good genotype for clopidogrel metabolism is associated with decreased blood viscosity in clopidogrel-treated ischemic stroke patients","authors":"J. Park, S. Han, Hyun-jeung Yu","doi":"10.18700/jnc.200023","DOIUrl":"https://doi.org/10.18700/jnc.200023","url":null,"abstract":"Background: Blood viscosity (BV) is a measurement of the intrinsic resistance of blood to flow, and high BV increases thromboembolic risk. Although laboratory documentation of clopidogrel resistance has been shown to predict an increased risk of cardiovascular events in patients with ischemic stroke, there is no evidence that cytochrome P450 2C19 (CYP2C19) polymorphisms in clopidogrel-treated patients influence BV after ischemic stroke. Methods: Patients with ischemic stroke or transient ischemic attack within 7 days of symptom onset from April 2018 to October 2019 were included. Patients were classified into the good genotype group for clopidogrel metabolism (ultrarapid or extensive metabolizer) and poor genotype group (intermediate/unknown or poor metabolizer) based on their CYP2C19 genotype status. A scanning capillary-tube viscometer was used to assess whole BV, and patients were divided into decreased BV and increased BV groups. Results: The final analyses included 174 patients (109 men and 65 women) with a mean age of 66.4±11.2 years. The good genotype was found in 44% of patients with decreased systolic BV (SBV) and 27% of those with increased SBV (P=0.029), suggesting that BV changes were related to the CYP2C19 genotype for clopidogrel metabolism. Binary logistic regression analysis showed that CYP2C19 genotype status (P=0.024) and baseline SBV (P<0.001) were significantly associated with decreased BV. The good genotype for clopidogrel metabolism was associated with decreased BV in patients with ischemic stroke treated with clopidogrel. Conclusion: The present results indicate that the effect of clopidogrel treatment on ischemic stroke prevention could be modulated not only by inhibition of platelet function but also by changes in the hemorheological profile.","PeriodicalId":33246,"journal":{"name":"Journal of Neurocritical Care","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48734089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Central skull base osteomyelitis due to nasopharyngeal Klebsiella infection 鼻咽部克雷伯菌感染所致中枢性颅底骨髓炎

Journal of Neurocritical Care Pub Date : 2020-12-24 DOI: 10.18700/jnc.200017

Kyoungnam Woo, J. Roh, S. Baik, D. Shin, Ki-Seok Park, M. Park, K. Park, Sung-Ho Ahn

{"title":"Central skull base osteomyelitis due to nasopharyngeal Klebsiella infection","authors":"Kyoungnam Woo, J. Roh, S. Baik, D. Shin, Ki-Seok Park, M. Park, K. Park, Sung-Ho Ahn","doi":"10.18700/jnc.200017","DOIUrl":"https://doi.org/10.18700/jnc.200017","url":null,"abstract":"Skull base osteomyelitis (SBO) is a rare but life-threatening disease usually seen as a complication of otitis externa [1]. It initially involves the lateral part of the temporal bone and extends to the petrous apex and clivus [2], accompanied by bone erosion, thrombophlebitis, and hematogenous seeding [3]. Thus, patients with SBO typically present with otalgia, otorrhea, hearing loss, and cranial nerve dysfunction in the immunocompromised, particularly older diabetic patients [4]. Central skull base osteomyelitis due to nasopharyngeal Klebsiella infection Kyoung-Nam Woo, MD; Jieun Roh, MD; Seung-Kug Baik, PhD; Dong-Hyeon Shin, MD; Ki-Seok Park, MD; Min-Gyu Park, PhD; Kyung-Pil Park, PhD; Sung-Ho Ahn, MD Department of Neurology, Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Busan, Republic of Korea Department of Radiology, Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Busan, Republic of Korea CASE REPORT","PeriodicalId":33246,"journal":{"name":"Journal of Neurocritical Care","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47289359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1