Jurnal Profesi Medika最新文献_第9页

The Effect of High-Intensity Interval Training on Blood Lactate Levels and Rate of Perceived Exertion in Sedentary Healthy Adults 高强度间歇训练对久坐健康成年人血乳酸水平和运动感知率的影响

Jurnal Profesi Medika Pub Date : 2022-12-12 DOI: 10.33533/jpm.v16i2.5104

Nur Ahlina Damayanti, N. Nusdwinuringtyas, Tresia Fransiska Uliana Tambunan, A. Kekalih

引用次数: 0

The Relationship Between Mallampati Score And Obesity With the Risk of OSAHS in Down Syndrome Children Mallampati评分与肥胖与唐氏综合征儿童OSAHS风险的关系

Jurnal Profesi Medika Pub Date : 2022-12-10 DOI: 10.33533/jpm.v16i1.3960

U. Gamayani, Agnes Christine Yolanda Sihite, Iin Pusparini, N. Lailiyya

{"title":"The Relationship Between Mallampati Score And Obesity With the Risk of OSAHS in Down Syndrome Children","authors":"U. Gamayani, Agnes Christine Yolanda Sihite, Iin Pusparini, N. Lailiyya","doi":"10.33533/jpm.v16i1.3960","DOIUrl":"https://doi.org/10.33533/jpm.v16i1.3960","url":null,"abstract":"Obstructive Sleep Apnea/Hypopnea Syndrome (OSAHS) has commonly occured in Down syndrome children caused by the abnormalities in upper respiratory tract anatomy and obesity. This study aims to identify the correlation between Mallampati score and obesity and the risk of OSAHS in Down syndrome children. This was an analytical descriptive cross-sectional study. This study was conducted in children with Down syndrome from September until November 2017. All parents filled the Indonesian Pediatric Sleep Questionnaire (PSQ), then all of the children were examined for Mallampati score and BMI. The correlation was analyzed by the Pearson Chi-Square model. Thirty-six subjects were included in this study. The number of male subjects were slightly more (61.1%), the mean age of the subjects was 8.42±4,449 years, with 52.8% (19 subjects) having OSAHS. There were 23 subjects (63.9%) who had Mallampati scores of 3 and 4, with 13 subjects (36.1%) were obese. This study concluded a statistically significant correlation between Mallampati score and obesity and the risk of OSAHS in Down syndrome children (p-value 0.001 and 0.029). Mallampati score and obesity had a significant correlation with the risk of OSAHS in Down syndrome children. ","PeriodicalId":33234,"journal":{"name":"Jurnal Profesi Medika","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49268512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Risk of Back Pain in Faculty of Medicine UPN Veteran Jakarta Students During Online Lectures in the 2020 COVID-19 Pandemic Era 2020年新冠肺炎大流行时代在线讲座期间，UPN医学院雅加达资深学生的背痛风险

Jurnal Profesi Medika Pub Date : 2022-12-09 DOI: 10.33533/jpm.v16i2.4815

Dwi Arwandi Yogi Saputra, Hermawan Saputra, Sutoto Sutoto

引用次数: 0

Comparison in Levels of Interleukin 6, Ferritine and Neutrophil-Lymphocyte Ratio in COVID-19 Patiens Treated in ICU and Non-ICU 重症监护病房与非重症监护病房患者白细胞介素6、铁氨酸水平及中性粒细胞淋巴细胞比值的比较

Jurnal Profesi Medika Pub Date : 2022-12-07 DOI: 10.33533/jpm.v16i2.4891

Nanda Oktavia, Efrida Efrida, Z. Rofinda

{"title":"Comparison in Levels of Interleukin 6, Ferritine and Neutrophil-Lymphocyte Ratio in COVID-19 Patiens Treated in ICU and Non-ICU","authors":"Nanda Oktavia, Efrida Efrida, Z. Rofinda","doi":"10.33533/jpm.v16i2.4891","DOIUrl":"https://doi.org/10.33533/jpm.v16i2.4891","url":null,"abstract":"Inflammation is caused by infectious diseases, including COVID-19. Severe inflammatory responses contribute to weak adaptive immune response, there by resulting in immune response imbalance. Circulating biomarkers can represent inflammation and immune status are potential predictors for the prognosis of COVID-19 patients. Ferritin and interleukin-6 can serve as significant biomarkers in the detection of cytokine storm, systemic inflammation, and the prognosis of COVID-19. Neutrophil-lymphocyte ratio is an independent prognostic biomarker for COVID-19 patients. The aim of this study to determine differences levels of IL-6, ferritin, and NLR in COVID-19 patients treated ICU and non-ICU. This study was comparative cross-sectional design of 62 COVID-19 patients. Research was conducted at the Central Laboratory and Medical Record of Dr. M. Djamil Padang hospital (May-September 2021). Interleukin-6 levels determined the ECLIA methods, ferritin with the ELFA methods, and NLR with calculation methods. Bivariate data were analyzed with Mann-Whitney test. The characteristics of COVID-19 patients treated in ICU: 64.5% male, average age was 53.52(10.71) years, 48.4% death, and non ICU: female 71.0%, average 42.32 (12.22) years, and recovered 100%. The most common comorbid is hypertension. There were significant differences levels of IL-6, ferritin, and NLR in ICU and non-ICU patients with COVID-19 (p<0.001).","PeriodicalId":33234,"journal":{"name":"Jurnal Profesi Medika","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42388502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Methylene Blue: a Potential Novel Treatment in Diabetic Foot Ulcer 亚甲基蓝:一种潜在的治疗糖尿病足溃疡的新方法

Jurnal Profesi Medika Pub Date : 2022-12-06 DOI: 10.33533/jpm.v16i2.4792

Lintang Cahyaning Ratri, A. Nugrahani, G. Prabowo, J. H. Prajitno

引用次数: 0

Critically Ill Patient with Acute Exacerbation of Chronic Obstructive Pulmonary Disease Developing Sepsis and Potassium Disorder: a Case Report in Secondary Hospital Setting 慢性阻塞性肺疾病急性加重并发败血症和钾血症的危重患者:二级医院一例报告

Jurnal Profesi Medika Pub Date : 2022-12-06 DOI: 10.33533/jpm.v16i2.5071

Regia Anadhia Pinastika, Indah Rahmawati, Tiara Nadya Putrianda

{"title":"Critically Ill Patient with Acute Exacerbation of Chronic Obstructive Pulmonary Disease Developing Sepsis and Potassium Disorder: a Case Report in Secondary Hospital Setting","authors":"Regia Anadhia Pinastika, Indah Rahmawati, Tiara Nadya Putrianda","doi":"10.33533/jpm.v16i2.5071","DOIUrl":"https://doi.org/10.33533/jpm.v16i2.5071","url":null,"abstract":"Sepsis and electrolyte disturbances are frequently experienced among acute exacerbation of chronic obstructive pulmonary disease (AECOPD) patients. It is characterized by organ failure brought on by unbalanced host response to infection. A 63-year-old male presented to the hospital with the complaint of breathlessness with the oxygen saturation of 76%. The leukocyte level increased to 19.000 and the Potassium level decreased to 2.88. The combination of antibiotics, Potassium supplement, oxygen support through NRM of 15 liters per minute and symptomatic treatment were administered to the patient. The NRM was then changed to HFNC due to his worsening condition and successfully decreased oxygen demand. The patient’s condition has made a significant improvement after seven days of hospitalization. Patients with AECOPD are at higher risk of developing sepsis and electrolyte disturbances. Sepsis will change the biological system of the body due to different pathophysiology such as electrolyte imbalance and obviously engaged with the pathogenesis of ensuing regular intensifications. It is important for the clinicians to know the effective management for the patient, so that the critical phase can be passed even at the limited facilities. ","PeriodicalId":33234,"journal":{"name":"Jurnal Profesi Medika","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47204250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Capacity to Consent of People with Dementia: a Narrative Review from an Ethical Perspective 痴呆症患者的同意能力:从伦理角度的叙事回顾

Jurnal Profesi Medika Pub Date : 2022-12-06 DOI: 10.33533/jpm.v16i2.4744

Urfa Khairatun Hisan, N. Qomariyah, Kristina Elizabeth

{"title":"Capacity to Consent of People with Dementia: a Narrative Review from an Ethical Perspective","authors":"Urfa Khairatun Hisan, N. Qomariyah, Kristina Elizabeth","doi":"10.33533/jpm.v16i2.4744","DOIUrl":"https://doi.org/10.33533/jpm.v16i2.4744","url":null,"abstract":"People with dementia have impairment to execute daily life activities by presenting as a deterioration of mental processes, such as memory, thinking, reasoning, and judgment. Many participants in dementia research may lack the capacity to provide informed consent. Additional safeguards are needed for dementia research participants’ protection because of their vulnerability. Only after carefully weighing the risks and possible benefits for the participants in the research may it be decided to use vulnerable participants. The intention to prevent harm pushes against the removal of autonomy. This dilemma is the driving force behind this article's narrative review of the capacity to consent problems in dementia research. For this critical narrative review, we conducted a thorough search of Scopus, PubMed, and Wiley Open Library for literature addressing the ethical and legal issues on the capacity to consent of people with dementia. We outline the dilemmas and difficulties that surround them including the related ethical principles, the informed consent process, capacity to consent, and safeguards for the participant in research involving people with dementia.","PeriodicalId":33234,"journal":{"name":"Jurnal Profesi Medika","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69572620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Vascular Risk Factor and Cognitive Impairment in Elderly 老年人血管危险因素与认知功能障碍

Jurnal Profesi Medika Pub Date : 2022-11-25 DOI: 10.33533/jpm.v16i2.4601

Rohmania Setiarini, Made Rika Anastasia Pratiwi, Mirzaulin Leonaviri

引用次数: 0

Toxigenic Diphtheriae Profile in Children in 2017-2018 2017-2018年儿童产毒性白喉概况

Jurnal Profesi Medika Pub Date : 2022-11-15 DOI: 10.33533/jpm.v16i2.4865

S. Maemun, Aninda Dinar Widiantari, Nur Aliza, M. Pane, T. Y. Setianingsih, Yeni Afrina, Farida Murtiani

{"title":"Toxigenic Diphtheriae Profile in Children in 2017-2018","authors":"S. Maemun, Aninda Dinar Widiantari, Nur Aliza, M. Pane, T. Y. Setianingsih, Yeni Afrina, Farida Murtiani","doi":"10.33533/jpm.v16i2.4865","DOIUrl":"https://doi.org/10.33533/jpm.v16i2.4865","url":null,"abstract":"Corynebacterium diphteriae is divided based on its ability to produce toxin. Toxigenic C. diphteriae is the type that has capacity to produce toxin and life threatening. This study was descriptive study in Corynebacterium diphteriae found in children less than 18 years old who were administered to National Infection Center Prof. Dr. Sulianti Saroso. We found 36 viable toxigenic C. diphteriae isolates, which 52.8% intermedius strain, 33.3% gravis strain, 8.3% mitis, and 5.6% non-strain. Most of the host (52,8%) were 60-144 months years old. Majority of the host had completed basic vaccination recommended by Indonesian Paediatrician Association while 75% of them hadn’t gotten the supplementary doses. Fever (48.5%) and odynophagia (54.5%) were experienced by toxigenic intermedius strain infection. Snoring (50%) and thick pseudomembran mostly found in gravis strain host while Bullneck sign found in intermedius strain infection. Complications like airway obstruction, chronic kidney disease, and myocarditis were found in host with toxigenic intermedius strain by 66.7%, 100%, and 75%. Death case were also mostly with this strain. Intermedius strain were mostly found in this study. Complications and mortality were also connected to intermedius strain infection.","PeriodicalId":33234,"journal":{"name":"Jurnal Profesi Medika","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43861170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Isolation and Characterization of Adipose-Derived Mesenchymal Stem Cell Exosomes: an In-Vitro Study 脂肪来源的间充质干细胞外泌体的分离和表征:一项体外研究

Jurnal Profesi Medika Pub Date : 2022-11-15 DOI: 10.33533/jpm.v16i2.4867

J. Fiolin, I. H. Dilogo, R. Antarianto, Ludwig Andre Pontoh

{"title":"Isolation and Characterization of Adipose-Derived Mesenchymal Stem Cell Exosomes: an In-Vitro Study","authors":"J. Fiolin, I. H. Dilogo, R. Antarianto, Ludwig Andre Pontoh","doi":"10.33533/jpm.v16i2.4867","DOIUrl":"https://doi.org/10.33533/jpm.v16i2.4867","url":null,"abstract":"Exosomes from Mesenchymal Stem Cells (MSC) is currently one of the highlighted research due to its more specific action on the target tissue. Exosome is one of the MSC Extracellular Vesicle (EVs) that acts as a mediator in the cellular communication. However, not so many literatures have succeed in elaborating its isolation and characterization process. This study aimed to explain the method used in exosomes isolation from Adipose-Derived MSC (ASC) and elaborate its characteristics. This is an in-vitro study performed in the Stem Cell and Tissue Engineering (SCTE) Indonesia Medical Education and Research Institute (IMERI) laboratory. Ultracentrifugation method was performed to isolate exosome from ASC. The exosome were characterized based on its particle size, morphology, and CD63 and CD81 expression for its purity. We were able to isolate sterile exosome from ASC by performing differential ultracentrifugation. The mean size of exosome was 88.7 nm ± 40 nm SD and showed expression of CD63 and CD81. Exosome was successfully isolated from ASC using ultracentrifugation method and characterization following the MISEV standard should be implemented in order to meet the therapeutic efficacy and safety issues as a regenerative agent.","PeriodicalId":33234,"journal":{"name":"Jurnal Profesi Medika","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43173068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1