{"title":"Management of Rhegmatogenous Retinal Detachment: Tips and Tricks for The Beginners","authors":"L. Gopal","doi":"10.35479/IJRETINA.2019.VOL002.ISS001.69","DOIUrl":"https://doi.org/10.35479/IJRETINA.2019.VOL002.ISS001.69","url":null,"abstract":"Lingam Gopal, National University Health system, Singapore, gopal_lingam@nuhs.edu.sg INTRODUCTION In the portfolio of a vitreo retinal surgical practice, management of retinal detachments occupies the premium position. The following serves as an introduction with a philosophical slant rather than as a detailed listing of the dos and don’ts. It is primarily addressed to the vitreo retinal trainee. Hence, I would like to offer an advance apology to the trained and experienced retinal surgeons who may browse through this article.","PeriodicalId":33128,"journal":{"name":"IJRETINA International Journal of Retina","volume":"486 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86776120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Usher Syndrome in Two Siblings, A Case Report","authors":"Teddy Kristiyan, N. Dewi, Safaruddin Refa","doi":"10.35479/IJRETINA.2019.VOL002.ISS001.66","DOIUrl":"https://doi.org/10.35479/IJRETINA.2019.VOL002.ISS001.66","url":null,"abstract":"Introduction: Usher Syndrome is a rare genetic disorder involving abnormalities in the retina and hearing, where the patients will experience blindness and hearing loss due to mutations of the gene. Blindness caused by Usher Syndrome has not been prevented until now, but the emphasis is more on focusing early diagnosis, especially patients with Retinitis Pigmentosa. \u0000Methods: This Case represent of two siblings with Retinitis Pigmentose (RP) and profound bilateral sensorineural deafness. Diagnosis based on patients decreases of vision since teenagers and worst at night, visual acuity and visual field examination in both patients, Ophthalmoscopic findings, and sensorineural deafness diagnosed by Ear, Nose, and Throat (ENT) department. Electroretinogram (ERG) was not carried out in the two patients because of the limitations of diagnostic facilities. \u0000Result: In both eyes of both siblings, ophthalmoscopic evaluation disclosed numerous bone spiculae at peripheral area. Humphrey perimetry showed a tunnel vision. The hearing test also showed a sensorineural hearing loss (SNHL). \u0000Conclusion: two affected member of the family were found to exhibit an usher syndrome, this pedigree supports the genetic cotransmission of the traits.","PeriodicalId":33128,"journal":{"name":"IJRETINA International Journal of Retina","volume":"611 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77645016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. S. Wardhana, D. H. Sakti, S. Supanji, M. B. Sasongko, T. W. Widayanti, A. N. Agni
{"title":"Surgical Technique of Late Spontaneous IOL-Capsular Bag Complex Dislocation with Low Corneal Endothelial Cell Density: A Case Report","authors":"F. S. Wardhana, D. H. Sakti, S. Supanji, M. B. Sasongko, T. W. Widayanti, A. N. Agni","doi":"10.35479/IJRETINA.2019.VOL002.ISS001.54","DOIUrl":"https://doi.org/10.35479/IJRETINA.2019.VOL002.ISS001.54","url":null,"abstract":"Introduction: IOL-capsular bag complex dislocation is a rare but serious complication of phacoemulsification surgery. Technique to repair this complication should be based on various clinical parameters including quality of corneal endothelial cells and the type of dislocated IOL. \u0000Case Presentation: We present a case of a 67-year-old male with left eye spontaneous one-piece foldable IOL-capsular bag complex dislocation to vitreous cavity 4 years after phacoemulsification surgery. Visual acuity of the left eye was 1/60, pupil was round with 3 mm diameter and IOP was 15 mmHg. Noncontact specular microscopy examination showed that the corneal endothelial cell density was 1100 cells/mm2. It was managed with 23-gauge posterior vitrectomy, IOL evacuation to anterior chamber, releasing the capsular bag and repositioning the IOL into posterior chamber by sutured scleral fixation. \u0000Result: Follow-up at 6thmonth, best corrected visual acuity of the left eye achieved 6/6, IOL at central position and the last corneal endothelial cell density was 1076 cells/mm2. \u0000Conclusions: Late spontaneous IOL-capsular bag complex dislocation with low corneal endothelial cell density can be safely managed with proper surgical technique. Vitrectomy and sutured scleral fixation of the previously dislocated IOL were effective in managing such case. Longer follow-up should be done to assure the stability of IOL position and the quality of corneal endothelial cells.","PeriodicalId":33128,"journal":{"name":"IJRETINA International Journal of Retina","volume":"74 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80655934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Characteristics of Patient with Macular Hole After Pars Plana Vitrectomy (PPV) and Internal Limiting Membran (ILM) Peeling in Cicendo Eye Hospital National Eye Center, Bandung","authors":"Rani Pitta Omas","doi":"10.35479/IJRETINA.2019.VOL002.ISS001.61","DOIUrl":"https://doi.org/10.35479/IJRETINA.2019.VOL002.ISS001.61","url":null,"abstract":"Introduction : Macular hole (MH) can cause severe visual disturbance, but remarkable progress has been achieved in surgical treatment for eyes with this condition. Vitrectomy with internal limiting membrane (ILM) peeling allows a very high success rate for MH closure (approaching 90%). To compare characteristics patients with closed and unclosed macular hole after pars plana vitrectomy (PPV) surgery and internal limiting membran (ILM) peeling. \u0000Method : This was retrospective study which data was obtain from patient’s medical records who underwent PPV and ILM peeling since July 1st to December 31th 2018. \u0000Results : 27 eyes from 25 patients had MH surgery. 20 eyes (74%) had closed MH and 7 (26%) eyes unclosed MH after surgery. HFF value before surgery was 1,34 ± 0,90 and MHI was 1,09 ± 0,81 in closed MH. Meanwhile in unclosed MH, HFF value before surgery 0,53 ± 0,12 and MHI was 0,75 ±0,10. MHI ≥0,5 and HFF value ≥ 0,9 had a good prognostic factor. \u0000Conclusion : Despite of good prognostic factor from OCT measurement and achieve anatomical success, foveal microstructure also important in visual recovery after MH surgery.","PeriodicalId":33128,"journal":{"name":"IJRETINA International Journal of Retina","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90515241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Effect of Citicoline on Electroretinography Abnormalities in Patients with Non-proliferative Diabetic Retinopathy","authors":"Anna Nur Utami, Elvioza Elvioza, M. Sidik","doi":"10.35479/ijretina.2019.vol002.iss001.53","DOIUrl":"https://doi.org/10.35479/ijretina.2019.vol002.iss001.53","url":null,"abstract":"Introduction : to determine the effect of citicoline 1000 mg oral supplementation given for 4 weeks on electroretinography abnormalities in patients with NPDR (non-proliferative diabetic retinopathy). \u0000Methods : prospective, double blind, randomized clinical trial. Thirty-eight patients who matched the inclusion and exclusion criteria were randomized into two groups: the placebo (P-NPDR) and citicoline (C-NPDR). In the end, there were 18 eyes in citicoline group and 16 eyes in placebo group. The primary outcome was P50 and N95 amplitude in PERG within group and intergroup which were taken at the baseline and 4 weeks after treatment. \u0000Results : at the end of treatment, the N95 amplitude in C-NPDR showed improvement, 4.85 (1.9-10.3) µV, before treatment to 5.7 (1.9-17.1) µV, after treatment with P = 0.04. Median P50 amplitude improved in both groups, with C-NPDR: 3.1 µV to 3.8 µV (p = 0.89), and P-NPDR: 3.5 µV, to 4.5 µV (p = 0.10). Delta ∆N95 amplitude is higher in C-NPDR, while delta ∆P50 amplitude is higher in P-NPDR, with P values 0.35 and 0.45. \u0000Conclusion : Oral citicoline may induce a significant improvement in mean N95 amplitude before and after the treatment. P-NPDR showed positive trend in P50 amplitude while in C-NPDR showed positive trend in N95 amplitude, but these values were not statistically significant (P = 0.45; P= 0.35).","PeriodicalId":33128,"journal":{"name":"IJRETINA International Journal of Retina","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91153045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"THE EFFECT OF MANGOSTEEN (GARCINIA MANGOSTANA) PERICARP EXTRACT ON RETINOBLASTOMA CELL CULTURE PROLIFERATION","authors":"Fariz Nufiarwan, Lely Retno Wulandari","doi":"10.35479/ijretina.2019.vol002.iss001.59","DOIUrl":"https://doi.org/10.35479/ijretina.2019.vol002.iss001.59","url":null,"abstract":"Introduction: To determine the effect of mangosteen (Garcinia mangostana) pericarp extracts on retinoblastoma cell culture proliferation. \u0000Methods: This study is a true experimental in vitro design with pre and post-test control group design. Research using retinoblastoma cell culture exposed by mangosteen pericarp extract (Garcinia mangostana) at a dose of 10 µg/ml, 20 µg/ml, and 40 µg/ml. \u0000Result: This study used retinoblastoma cell line cultures were obtained from the American Type Culture Collection (ATCC) 10801 University Boulevard Manassas, VA 20110 USA. The samples were divided into 4 groups: control group and 3 groups treated with doses of 10 µg/ml, 20 µg/ml and 40 µg/ml and then incubated for 48 hours, and then examined using MTT Cell Proliferation Assay. Group 1 (10 µg/ml) obtained a decrease of 151.8%, group 2 (20 µg/ml) of 134.6% and group 3 (40 µg/ml) of 134.36%. \u0000Conclusion: Mangosteen pericarp extract (Garcinia mangostana) can reduce retinoblastoma culture cell proliferation.","PeriodicalId":33128,"journal":{"name":"IJRETINA International Journal of Retina","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82693306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fenti Kusumawardhani Hidayah, N. Dewi, Safaruddin Refa
{"title":"Profile of Patients with Floaters in Saiful Anwar Hospital Malang","authors":"Fenti Kusumawardhani Hidayah, N. Dewi, Safaruddin Refa","doi":"10.35479/IJRETINA.2018.VOL001.ISS002.31","DOIUrl":"https://doi.org/10.35479/IJRETINA.2018.VOL001.ISS002.31","url":null,"abstract":"Introduction: To report the profile of patients with floaters as a subjective complain in Saiful Anwar Hospital from July 2012 until June 2013. \u0000Methods: an observasional descriptive study was conducted, collecting data on gender, age, subjective complain (floaters, flashes and subjective vision reduction), best corrected visual acuity and diagnose from patient’s medical record. \u0000Result: 169 patients (215 eyes) were included in this study. Female patients contributed a higher percentage than male with mean of age was 49 years old. The subjective complain was floaters (67%), floater with blurred vision (22%), floater with flashes (6%) and patients with floaters, flashes, and blurred vision was 5%. Myopia was the most common refraction problem. Diagnose recorded from this study were posterior vitreous detachment (PVD) (34%), no abnormalities (13%), PDR (10%), RRD (9%), peripheral retinal degeneration (14%) retinal break (6%), corpus vitreous degeneration (3%), vitreous haemorhage (3%), posterior uveitis (2%) and others (6%). \u0000Conclusion: The most common cause of floaters is PVD. Even it is usually a save condition but there are some condition with floater as a subjective complain which is threatening vision, so accurate eye examination from anterior to posterior segment were needed.","PeriodicalId":33128,"journal":{"name":"IJRETINA International Journal of Retina","volume":"49 3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90649879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Outcome of Vitrectomy Surgery in Dropped Nucleus at Jakarta Eye Center","authors":"Referano Agustiawan, Elvioza Elvioza, Soedarman Sjamsoe, Waldensius Girsang","doi":"10.35479/ijretina.2018.vol001.iss002.28","DOIUrl":"https://doi.org/10.35479/ijretina.2018.vol001.iss002.28","url":null,"abstract":"Introduction: To report management and outcome of dropped nucleus in Jakarta Eye Center \u0000Methods: Retrospective review of the records of 19 consecutive patients who underwent pars plana vitrectomy for retain lens fragments at Jakarta Eye Center from January 2010 to September 2012. \u0000Result: The mean age of the patient was 57 years (range 48-79). There were 10 males (53%) and 9 females (47%). 10 patients (53%) had vitrectomy within 1 day of phacoemulsification, 6(32%) within 1 week and 3(15%) after more than 1 week. Eight patients (42%) achieved a final visual acuity of 0.5 or better, only 3 patients (15%) had final visual acuity 1-meter finger counting or worse. 74% patient achieved final acuity better than pre-op (14 patients). Early vitrectomy group has 3 patients (30%) with complication, intermediate vitrectomy group has 33% complication and late vitrectomy has 33 % complication. Posterior chamber IOL were implanted in 12 patients (63%), 2 patients had scleral fixation IOL, anterior chamber IOL in 2 patients, and only 3 patients (16%) were left aphakic. \u0000Conclusion: Surgical management in cases of nucleus drop in JEC showed good result with very limited complications. In most cases, vitrectomy was performed immediately after cataract surgery. Early vitrectomy has no significant differences in complications and visual outcome than 1 week vitrectomy and late vitrectomy after cataract surgery. \u0000 ","PeriodicalId":33128,"journal":{"name":"IJRETINA International Journal of Retina","volume":"36 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81364778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mirza Metita, Yorihisa Kitagawa, H. Shimada, H. Nakashizuka
{"title":"Polypoidal Choroidal Vasculopathy","authors":"Mirza Metita, Yorihisa Kitagawa, H. Shimada, H. Nakashizuka","doi":"10.35479/IJRETINA.2018.VOL001.ISS002.46","DOIUrl":"https://doi.org/10.35479/IJRETINA.2018.VOL001.ISS002.46","url":null,"abstract":"Introduction: to report a case of PCV that has been successfully treated with intravitreal injection of t-PA, ranibizumab, and pneumatic displacement. \u0000Method: A 65 years old man presented with blurred vision of his right eye. No systemic abnormalities were found. Initial visual acuity RE was 6/18. Funduscopy examination showed submacular hemorrhage in posterior pole. OCTA, FA and ICG confirmed the diagnosis of PCV. We performed anterior chamber paracentesis and intravitreal injection of 0,05 ml t-PA, 0,05 ml ranibizumab, and 0,3 ml 100% C3F8 at a time in retrobulbar anesthesia. The patient was instructed to maintain face down positioning for 2 days. \u0000Results: We evaluated the visual acuity, central retinal thickness (CRT), and central pigment epithelial detachment (PED) thickness for 2 years. The visual acuity was increasing gradually from 6/18 to 6/6 in the first year. The hemorrhage was displaced completely, the CRT and central PED thickness were decreased. In the second year the patient had recurrence of PCV with serous retinal detachment and treated with intravitreal aflibercept. \u0000Conclusion: Combined treatment of intravitreal t-PA, ranibizumab, and C3F8 can be used as a beneficial therapy for PCV.","PeriodicalId":33128,"journal":{"name":"IJRETINA International Journal of Retina","volume":"91 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75929735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Anti-VEGF Therapy In Central Retinal Vein Occlusions","authors":"Meidina Rahmah, Ramzi Amin, Ak Ansyori","doi":"10.35479/IJRETINA.2018.VOL001.ISS002.42","DOIUrl":"https://doi.org/10.35479/IJRETINA.2018.VOL001.ISS002.42","url":null,"abstract":"Introduction: Central retinal vein occlusion (CRVO) is the second most common retinal vascular disease after diabetic retinopathy and is estimated to affect more than 16 million adults worldwide. Treating the underlying cause of occlusion of the central retinal vein, reducing the risk factors, and early and proper management are the keys toward a better prognosis in patients with CRVO. Repeated frequent treatment of CRVO with macular edema with intravitreal anti-vascular endothelial growth factor (anti-VEGF) is an effective treatment to improve visual outcome. In this case report we assess the 3-month efficacy of anti-VEGF therapy in CRVO. \u0000Method: In this case, a 52-year-old man presented with an acute loss of vision over the last week in his left eye. His baseline visual acuity was 1/60 and his central retinal thickness (CRT) on Optical Coherence Tomography (OCT) was 523 μm. Fundus examination revealed a hemorrhage in all four quadrants, hard exudates, swelling of the optic nerve, and macular edema. Laboratory test confirms hyperlipidemia and we consult this patient to Internal Medicine Department. This patient got 3 monthly injections of 1,25 mg Bevacizumab. \u0000Results: By 3 months, the OCT appeared fairly normal and the visual acuity improved to 6/60 \u0000Conclusion: Anti-VEGF therapy is effective for treating macular edema secondary to CRVO","PeriodicalId":33128,"journal":{"name":"IJRETINA International Journal of Retina","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80770205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}