The Internet Journal of Thoracic and Cardiovascular Surgery最新文献_第10页

Effects of Palm Oil Supplementation on Lipid Peroxidation and Glutathione Peroxidase Activity in Cholesterol – Fed Rats 补充棕榈油对胆固醇喂养大鼠脂质过氧化和谷胱甘肽过氧化物酶活性的影响

The Internet Journal of Thoracic and Cardiovascular Surgery Pub Date : 2008-12-31 DOI: 10.5580/2620

O. Oluba, C. Onyeneke, G. Ojieh, G. Eidangbe, R. Orole

引用次数: 9

Repair of Three Valves in a Single Operation 在一次操作中修理三个阀门

The Internet Journal of Thoracic and Cardiovascular Surgery Pub Date : 2008-12-31 DOI: 10.5580/1d77

C. Özbek, U. Yetkin, N. Postac, Tevfik Güne, A. Durmu, A. Gürbüz

引用次数: 0

Analysis of nsSNP rs1468384 of NPC1L1 and its association with plasma cholesterol levels in general population NPC1L1的nsSNP rs1468384及其与普通人群血浆胆固醇水平的关系分析

The Internet Journal of Thoracic and Cardiovascular Surgery Pub Date : 2008-12-31 DOI: 10.5580/81c

P. Balgir, Divya Khanna, Gurlovleen Kaur

{"title":"Analysis of nsSNP rs1468384 of NPC1L1 and its association with plasma cholesterol levels in general population","authors":"P. Balgir, Divya Khanna, Gurlovleen Kaur","doi":"10.5580/81c","DOIUrl":"https://doi.org/10.5580/81c","url":null,"abstract":"Niemann-Pick C1 �like 1 (NPC1L1) protein, a newly identified sterol influx transporter, located at the apical membrane of the enterocyte, which may actively facilitate the uptake of cholesterol by promoting the passage of sterols across the brush border membrane of the enterocyte. It effects intestinal cholesterol absorption and intracellular transport and as such is an integral part of complex process of cholesterol homeostasis. The study of population data for the distribution of these SNPs of NPC1L1 has lead to the identification of six nsSNPs (non-synonymous single nucleotide polymorphism). The in vitro analysis using the software MuPro and StructureSNP shows that nsSNP M510I (rs1468384), which involves A!iG base pair change leads to decrease in the stability of the protein. A reproducible and a cost-effective PCR-RFLP based assay was developed to screen for the SNP distribution amongst the North Western Indian population as a test case. This SNP has been studied in Caucasian, Asian and African American populations. Till date, no data is available on Indian population. The allele distribution in Indian Population differs significantly from that of other populations. Moreover on investigating the effect of this nsSNP on the plasma lipid levels in the general population we found a profound association of this nsSNP with higher ranges of plasma lipid levels.","PeriodicalId":330833,"journal":{"name":"The Internet Journal of Thoracic and Cardiovascular Surgery","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133016094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Trans-mediastinal migration of Bullet – an unusual presentation 子弹的跨纵隔迁移-一种不寻常的表现

The Internet Journal of Thoracic and Cardiovascular Surgery Pub Date : 2008-12-31 DOI: 10.5580/1911

Nityasha, S. Dalal, R. Dahiya, S. Aggarwal, S. Lohchab

引用次数: 0

Microanatomical Differences between Pangolin (Manis tricuspis) and Rat Ascending Aortae 穿山甲与大鼠升主动脉的显微解剖差异

The Internet Journal of Thoracic and Cardiovascular Surgery Pub Date : 2008-12-31 DOI: 10.5580/257f

L. Medubi, O. R. Jimoh, O. Ghazal, G. Adefolaju

引用次数: 0

evaluation of thoracoscopic management of thoracic trauma 胸腔镜治疗胸外伤的评价

The Internet Journal of Thoracic and Cardiovascular Surgery Pub Date : 2008-12-31 DOI: 10.5580/1077

Suresh Kumar, Ramakant, A. Rai, Sunil Kumar, Surendra Kumar, J. Kumar, R. Garg

引用次数: 0

Revision for postoperative bleeding: timing and decision making 术后出血的翻修:时机和决策

The Internet Journal of Thoracic and Cardiovascular Surgery Pub Date : 2008-12-31 DOI: 10.5580/16c6

U. Yetkin, smail Yürekli, A. Gürbüz

引用次数: 1

Plasma Lipid Profiles in Hypertensive Nigerians 尼日利亚高血压患者血浆脂质谱

The Internet Journal of Thoracic and Cardiovascular Surgery Pub Date : 2008-12-31 DOI: 10.5580/117f

J. Idemudia, E. Ugwuja

{"title":"Plasma Lipid Profiles in Hypertensive Nigerians","authors":"J. Idemudia, E. Ugwuja","doi":"10.5580/117f","DOIUrl":"https://doi.org/10.5580/117f","url":null,"abstract":"Background: The association between hypertension and dyslipidaemia is well established and both may add up to increase patients’ susceptibility to the development of coronary heart disease. Methods: Lipid profiles were studied in one hundred and fifty (150) hypertensive patients aged 30-59 years and thirty (30) ageand socio-economically matched normotensive controls using standard laboratory techniques. Results: Of the 150 hypertensive patients, 54% (n = 69) were females with majority (45.7%) in the age range 50-59 years while majority (53.6%) of hypertensive males were in the age group 40-49 years. Hypertensive patients have significantly higher lipid profile except for HDL-Cholesterol, which did not show any significant difference in the two groups. Among the hypertensive patients, total cholesterol was positively correlated with triglyceride (0.399,p < 0.05), LDL-cholesterol (r = 0.609,p < 0.05) and HDLcholesterol (r = 0.866,p < 0.05) and HDL-C positively correlated with LDL-C (r = 0.218,p < 0.05). In normotensive patients however, LDL-cholesterol was negatively correlated with triglyceride (r = -0.409,p < 0.05) while total cholesterol was positively correlated with LDL-cholesterol (r = 0.876,p < 0.05). Conclusion: Hypertensive Nigerians have significantly elevated plasma total cholesterol, Triglyceride and LDL-C but comparable HDL-C with normotensives. The clinical implications of elevated HDL-C in hypercholesterolemic hypertensive Nigerians are unclear.","PeriodicalId":330833,"journal":{"name":"The Internet Journal of Thoracic and Cardiovascular Surgery","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126671031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 32

Kinking of left internal mammary artery graft exhibiting as false coiling entity 左乳内动脉移植物扭曲，表现为假卷曲实体

The Internet Journal of Thoracic and Cardiovascular Surgery Pub Date : 2008-12-31 DOI: 10.5580/1222

U. Yetkin, C. Özbek, M. Bademci, smail Yürekli, Murat Ye il, A. Gürbüz

{"title":"Kinking of left internal mammary artery graft exhibiting as false coiling entity","authors":"U. Yetkin, C. Özbek, M. Bademci, smail Yürekli, Murat Ye il, A. Gürbüz","doi":"10.5580/1222","DOIUrl":"https://doi.org/10.5580/1222","url":null,"abstract":"Coiling of the artery is a rare morphologic entity.We describe a case of kinking of left internal mammary artery graft exhibiting as false coiling entity INTRODUCTION Coiling (or looping) of the artery is a rare morphologic entity, most frequently described in the internal carotid artery. In other arteries, coiling is rarely reported because it remains asymptomatic and without clinical relevance unless inadvertently injured, as for diagnostic or monitoring purposes(1). The internal mammary artery is the most frequently used bypass conduit for the left anterior descending coronary artery in patients treated with bypass surgery, with excellent long-term patency rates. However, the mammary artery may also be affected by functionally significant stenoses. Most stenoses of the mammary artery are secondary to the surgical procedure at the anastomosis site, but atherosclerotic lesions may also develop(2). CASE PRESENTATION Our case was a 43-year-old male. His past medical history was significant for 3-vessel CABG and concomitant mitral ring annuloplasty at a different health facility 4 years ago. He was suffering from chest pain for 3 months. His coronary angiogram revealed stenoses in saphenous venous graft to the right coronary artery, in the native circumflex and left anterior descending arteries at postanastomotic segments. Percutaneous approach was planned for treatment. But during rehospitalization period, he suffered from fever and investigations identified a subacute bacterial endocarditis including the mitral valve (moderate mitral regurgitation and a vegetative mass of 1.9x0.9 cm on atrial face of mitral anterior leaflet). He was then referred to our clinic for reCABG and mitral valve exploration. His coronary angiogram showed a lesion of left internal mammarian artery graft consistent with coiling at right anterior oblique position (Figures 1&2).","PeriodicalId":330833,"journal":{"name":"The Internet Journal of Thoracic and Cardiovascular Surgery","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129442664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of adenosine A2A receptor low affinity agonist Regadenoson in patients with obstructive pulmonary disease, at risk for adenosine-induced bronchoconstriction mediated via A2B and/or A3 adenosine receptors. 腺苷A2A受体低亲和力激动剂Regadenoson在A2B和/或A3腺苷受体介导的有腺苷诱导支气管收缩风险的阻塞性肺疾病患者中的作用

The Internet Journal of Thoracic and Cardiovascular Surgery Pub Date : 2008-12-31 DOI: 10.5580/ff4

Stefan H. Meyering, H. Lomas

引用次数: 0