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2017 21st National Biomedical Engineering Meeting (BIYOMUT)最新文献

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Three Dimensional Bioprinting of Tissue Engineered Artificial Heart Valves by Stereolithography 组织工程人工心脏瓣膜的立体光刻三维生物打印
2017 21st National Biomedical Engineering Meeting (BIYOMUT) Pub Date : 2017-11-01 DOI: 10.1109/BIYOMUT.2017.8479071
Ali Akpek
{"title":"Three Dimensional Bioprinting of Tissue Engineered Artificial Heart Valves by Stereolithography","authors":"Ali Akpek","doi":"10.1109/BIYOMUT.2017.8479071","DOIUrl":"https://doi.org/10.1109/BIYOMUT.2017.8479071","url":null,"abstract":"Over the past several decades, there has been an everincreasing demand for organ transplants. There are no significant increase observed in organ donations while the need for organ transplantation is keep increasing. Organ donation emerges as the most feasible solution especially in heart valve diseases. There are two types of artificial heart valves are utilized for heart valve replacement operations. These are mechanical heart valves and bioprosthetic heart valves. However, there are severe intrinsic problems exist for both type of artificial heart valves that are hard to be solved. Due to these reasons, growing or fabricating tissue engineered heart valves using biomaterial scaffolds with a person’s own cells with high biocompatability. The purpose of this study is; fabricating 3D artificial heart valves by stereolithography that has potential to be obtained for heart valve replacements. Stereolithography has proven potential for fabricating 3D models with high structural integrity and strong mechanical properties, yet it has not been evaluated as a bioprinter. In this study, this purpose is aimed to be succeeded.","PeriodicalId":330319,"journal":{"name":"2017 21st National Biomedical Engineering Meeting (BIYOMUT)","volume":"60 6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123226164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Testing of the Jansen Cortical Columns Model to Simulate Different Brain Activities in MATLAB Jansen皮质柱模型在MATLAB中模拟不同脑活动的测试
2017 21st National Biomedical Engineering Meeting (BIYOMUT) Pub Date : 2017-11-01 DOI: 10.1109/BIYOMUT.2017.8479065
Ahmet Hıfzı Bacaksız, N. Sengor
{"title":"Testing of the Jansen Cortical Columns Model to Simulate Different Brain Activities in MATLAB","authors":"Ahmet Hıfzı Bacaksız, N. Sengor","doi":"10.1109/BIYOMUT.2017.8479065","DOIUrl":"https://doi.org/10.1109/BIYOMUT.2017.8479065","url":null,"abstract":"In this study, small vertical structures on the cortex, which are considered to be the basic units of sensory and motor information process known as cortical columns, have been investigated. In this context, a mass model, called Jansen's cortical column model, is implemented in the MATLAB programming language. Based on the results obtained, the existence of some brain activities during epilepsy seizure and alpha-wave have been examined.","PeriodicalId":330319,"journal":{"name":"2017 21st National Biomedical Engineering Meeting (BIYOMUT)","volume":"6 12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123420675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editing of Long Noncoding RNA DANCR Gene Locus Using Genetic Engineering Tools 利用基因工程工具编辑长链非编码RNA DANCR基因位点
2017 21st National Biomedical Engineering Meeting (BIYOMUT) Pub Date : 2017-11-01 DOI: 10.1109/BIYOMUT.2017.8478922
Gülin Baran, Burcu Talug, Nazlı Keskin, Zeynep Tokcaer Keskin, B. Erman, Emre Deniz
{"title":"Editing of Long Noncoding RNA DANCR Gene Locus Using Genetic Engineering Tools","authors":"Gülin Baran, Burcu Talug, Nazlı Keskin, Zeynep Tokcaer Keskin, B. Erman, Emre Deniz","doi":"10.1109/BIYOMUT.2017.8478922","DOIUrl":"https://doi.org/10.1109/BIYOMUT.2017.8478922","url":null,"abstract":"Long non-coding RNAs (lncRNAs) are defined as RNA transcripts that are longer than 200 nucleotides. By definition, these RNAs must not have open reading frames that encode proteins. We study the roles of lncRNA in DNA damage response (DDR). For this, we performed transcriptome analysis in human colorectal cancer cell line and mouse embryo fibroblast cells to elucidate differentially expressed lncRNAs in doxorubicin induced DNA damage. We identified DANCR lncRNA that is upregulated in DDR. The possible molecular functions of DANCR in DDR and in cell death remain to be discovered. In order to study functions of DANCR, we planned to create DANCR-/- cell lines using CRISPR/Cas9 genome engineering and editing tool. We aimed to remove DANCR from the genome without interfering the neighboring genes. After the cells are transfected with CRISPR/Cas9 constructs, they will be genotyped for confirming the deletion of the gene and they will be used to investigate the effects of the absence of DANCR in DDR with proliferation and apoptosis assays. This study will help to identify new players in DDR that will eventually shed light onto tumorigenesis and cancer treatment.","PeriodicalId":330319,"journal":{"name":"2017 21st National Biomedical Engineering Meeting (BIYOMUT)","volume":"71 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122968395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Parameter Estimation Approach to T1 and T2 Mapping in Phase-Cycled bSSFP Imaging 相位循环bSSFP成像中T1和T2映射的参数估计方法
2017 21st National Biomedical Engineering Meeting (BIYOMUT) Pub Date : 2017-11-01 DOI: 10.1109/BIYOMUT.2017.8479255
Kubra Keskin, T. Çukur
{"title":"Parameter Estimation Approach to T1 and T2 Mapping in Phase-Cycled bSSFP Imaging","authors":"Kubra Keskin, T. Çukur","doi":"10.1109/BIYOMUT.2017.8479255","DOIUrl":"https://doi.org/10.1109/BIYOMUT.2017.8479255","url":null,"abstract":"Relaxation times T1 and T2 can be estimated simultaneously from a phase cycled balanced steady state free precession (bSSFP) sequence, when the bSSFP signal is considered to have an elliptical signal model. Parameters of the model can be found by solving an ellipse specific linear least squares. Hence, estimation of the model parameters directly relies on the resulting ellipse fits. Therefore in the presence of highly deviated noise, estimations diverge from the true parameter values. In order to tackle this problem, a patch-based approach is presented in this study. With this approach, data points of the neighbor voxels are used to decrease the effect of noise on estimations. This method is compared with original ellipse fitting approach in terms of mean absolute percentage error and structural similarity.","PeriodicalId":330319,"journal":{"name":"2017 21st National Biomedical Engineering Meeting (BIYOMUT)","volume":"59 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128995190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A New Approach for Estimation of Heart Beat Rates from Speech Recordings 基于语音记录估计心率的新方法
2017 21st National Biomedical Engineering Meeting (BIYOMUT) Pub Date : 2017-11-01 DOI: 10.1109/BIYOMUT.2017.8478916
H. Ankishan, U. Baysal
{"title":"A New Approach for Estimation of Heart Beat Rates from Speech Recordings","authors":"H. Ankishan, U. Baysal","doi":"10.1109/BIYOMUT.2017.8478916","DOIUrl":"https://doi.org/10.1109/BIYOMUT.2017.8478916","url":null,"abstract":"Today, people are able to have information about their mental state, behavior, and health status in some issues from the features of the voices. The study involves calculating the heart rates of people using nonlinear equations with the help of the features of sound recordings. The model proposed for the study consists of the four inputs of the difference equation parameters which change with constant and variable sound features. When the experimental studies were examined, it was observed that the heart rate could be predicted with an accuracy of 89.76% by using 10s sound recordings. With the proposed equation, it is observed that the heart beat rate is related to the speech features, can be calculated these features with minimal error rate and also the nonlinear equation is presented in the literature.","PeriodicalId":330319,"journal":{"name":"2017 21st National Biomedical Engineering Meeting (BIYOMUT)","volume":"7 12","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"113941625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Monitoring of Diffuse Reflectance Spectra of Erythrocyte Suspensions during Storage 红细胞悬液贮存过程中漫反射光谱的监测
2017 21st National Biomedical Engineering Meeting (BIYOMUT) Pub Date : 2017-11-01 DOI: 10.1109/BIYOMUT.2017.8479000
Osman Melih Can, Ali Yekta Ulgen, A. Akın
{"title":"Monitoring of Diffuse Reflectance Spectra of Erythrocyte Suspensions during Storage","authors":"Osman Melih Can, Ali Yekta Ulgen, A. Akın","doi":"10.1109/BIYOMUT.2017.8479000","DOIUrl":"https://doi.org/10.1109/BIYOMUT.2017.8479000","url":null,"abstract":"Blood products are known to be deteriorating during storage. Recent efforts to determine the quality of blood products with a non-invasive technique during storage have gained momentum. Previous studies have shown that the degree of hemolysis, quality indicator for erythrocyte suspensions, correlates with the color parameters measured by noninvasive color measurement technique. In this study; we tried to model the diffuse reflectance values of the blood products, measured from the outside of the bag, and the physiological changes inside the blood with the mixed model. Experiments were performed on 24 unfiltered erythrocyte suspensions and 28 leukocyte filtered erythrocyte suspensions for 70 days of storage period. This paper contains the findings and the results obtained from the project realized in the Northern Marmara Region Blood Center with the permission of the General Directorate of Blood Services of the Turkish Red Crescent.","PeriodicalId":330319,"journal":{"name":"2017 21st National Biomedical Engineering Meeting (BIYOMUT)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130025307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development of Bending Artificial McKibben Muscle 弯曲人工麦基本肌的研制
2017 21st National Biomedical Engineering Meeting (BIYOMUT) Pub Date : 2017-11-01 DOI: 10.1109/BIYOMUT.2017.8479066
Beyza Golge, A. Yaman
{"title":"Development of Bending Artificial McKibben Muscle","authors":"Beyza Golge, A. Yaman","doi":"10.1109/BIYOMUT.2017.8479066","DOIUrl":"https://doi.org/10.1109/BIYOMUT.2017.8479066","url":null,"abstract":"McKibben artificial muscle has attracted attention in Robotics studies because of its similar characteristics with human muscles and its high power-weight ratio. McKibben muscles have the advantage in terms of safety due to its soft property especially in the field of rehabilitation robotics where human-robot interaction is more important. Furthermore the external loads on human body can be minimized. In this study, by changing the structure of McKibben muscle, it was provided that McKibben muscle was bended rather than shortened when compressed air was supplied. By using sensors, the relationship between input air pressure, bending angle and generated force was shown.","PeriodicalId":330319,"journal":{"name":"2017 21st National Biomedical Engineering Meeting (BIYOMUT)","volume":"241 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130406340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Newborn Hip Ultrasonography Training Phantom 新生儿髋关节超声训练幻影
2017 21st National Biomedical Engineering Meeting (BIYOMUT) Pub Date : 2017-11-01 DOI: 10.1109/BIYOMUT.2017.8479276
Ebrar Basborekci, Halit Koyuncu, A. Hamamci
{"title":"Newborn Hip Ultrasonography Training Phantom","authors":"Ebrar Basborekci, Halit Koyuncu, A. Hamamci","doi":"10.1109/BIYOMUT.2017.8479276","DOIUrl":"https://doi.org/10.1109/BIYOMUT.2017.8479276","url":null,"abstract":"Ultrasonography is the method that is routinely applied for screening and classification of hip dysplasia in newborns. Phantoms, that can mimic the acoustic characteristics of human tissues, are needed in ultrasound training or in the calibration of devices. In our study, polylactic acid (PLA) for simulating the bone tissue and gelatin for soft tissue were aimed to create a newborn hip ultrasonography phantom for training purposes.","PeriodicalId":330319,"journal":{"name":"2017 21st National Biomedical Engineering Meeting (BIYOMUT)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133173489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characterization of graphene oxide and reduced graphene oxide coating on gold electrodes by impedance spectroscopy 阻抗谱法表征氧化石墨烯及其在金电极上的还原氧化石墨烯涂层
2017 21st National Biomedical Engineering Meeting (BIYOMUT) Pub Date : 2017-11-01 DOI: 10.1109/BIYOMUT.2017.8479037
Fatma Gulden Simsek, B. Garipcan, Y. Ulgen
{"title":"Characterization of graphene oxide and reduced graphene oxide coating on gold electrodes by impedance spectroscopy","authors":"Fatma Gulden Simsek, B. Garipcan, Y. Ulgen","doi":"10.1109/BIYOMUT.2017.8479037","DOIUrl":"https://doi.org/10.1109/BIYOMUT.2017.8479037","url":null,"abstract":"In this study, the impedance spectroscopy is used as a detection tool in order to characterize graphene oxide and reduced graphene oxide coating on the gold surfaces. Gold surfaces are chosen as commercial surface electrodes. The impedance of redox solution through bare gold electrodes, graphene oxide and reduced graphene oxide coated gold electrodes is measured.","PeriodicalId":330319,"journal":{"name":"2017 21st National Biomedical Engineering Meeting (BIYOMUT)","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127655857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Constitutive modeling of bovine tendon 牛肌腱的本构模型
2017 21st National Biomedical Engineering Meeting (BIYOMUT) Pub Date : 2017-11-01 DOI: 10.1109/BIYOMUT.2017.8479147
B. Atakan, Samim Dundar, H. Yildiz
{"title":"Constitutive modeling of bovine tendon","authors":"B. Atakan, Samim Dundar, H. Yildiz","doi":"10.1109/BIYOMUT.2017.8479147","DOIUrl":"https://doi.org/10.1109/BIYOMUT.2017.8479147","url":null,"abstract":"In this study, tendons that holds skeletal and muscular system together are investigated with the help of hyperelastic material models and results of different material models are interpreted with the help of computer aided engineering programs. Axial forces are applied to bovine tendons in order to obtain stress-strain curve while doing constitutive modelling. After that, curve fitting methods are used to get the Mooney-Rivlin and Ogden constants. Constitutive model is formed by finite element model with the help of computer aided engineering programs and results of Mooney-Rivlin and Ogden models are examined.","PeriodicalId":330319,"journal":{"name":"2017 21st National Biomedical Engineering Meeting (BIYOMUT)","volume":"343 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115673165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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