Jurnal Respirasi最新文献_第10页

Ventilasi dan Perfusi, serta Hubungan antara Ventilasi dan Perfusi 通风口和扩散，以及通风口和扩散之间的联系

Jurnal Respirasi Pub Date : 2019-04-02 DOI: 10.20473/JR.V2-I.1.2016.29-34

Afrita Amalia Laitupa, M. Amin

{"title":"Ventilasi dan Perfusi, serta Hubungan antara Ventilasi dan Perfusi","authors":"Afrita Amalia Laitupa, M. Amin","doi":"10.20473/JR.V2-I.1.2016.29-34","DOIUrl":"https://doi.org/10.20473/JR.V2-I.1.2016.29-34","url":null,"abstract":"Lung is a place for gas exchange where ventilation and perfusion occurs. Ventilation is the first step where sequential process of inhalation and exhalation take place. Meanwhile perfusion as the other step facilitates the gas exchange and tissue supply need. Blood flows through the lungs are equals as the amount of cardiac output where the factors that control cardiac output are mainly peripheral factors, also control pulmonary blood flow. In general condition, pulmonary blood vessels act as a passive tube, which can be increased with the increasing pressure and narrowed the pressure drop. Oxygen absorption level from lungs into bloodstream is a critical determinant for functional capacity, and an important factor wheter in normal conditions (including exercise) or even in illness state. Lung diffusion capacity is influenced by several geometric and functional factors. Gravitation influence systematic gradient in ventilation and perfusion distribution. Ventilation and blood flow variations at horizontal level also occur due to intrinsic anatomic variations and vascular geometry, as well as the differences in airway and vascular smooth muscle response which modifies the distribution. The change of integrity intrapleural chamber, hydrostatic pressure and osmotic imbalance, malfunction of surfactants, other intrinsic weakness of the branching system in the form of a progressive airway, and all the things that could potentially damage the structure of the lung can cause ventilation and diffusion dysfunction.","PeriodicalId":328612,"journal":{"name":"Jurnal Respirasi","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128250471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Seorang Laki-Laki dengan Tumor Mediastinum Posterior ( Malignant Peripheral Nerve Sheath Tumor ) 后纵隔瘤(恶性周围神经鞘瘤)

Jurnal Respirasi Pub Date : 2019-04-02 DOI: 10.20473/JR.V2-I.3.2016.82-90

Daniel Maranatha, S. Yuniati

{"title":"Seorang Laki-Laki dengan Tumor Mediastinum Posterior ( Malignant Peripheral Nerve Sheath Tumor )","authors":"Daniel Maranatha, S. Yuniati","doi":"10.20473/JR.V2-I.3.2016.82-90","DOIUrl":"https://doi.org/10.20473/JR.V2-I.3.2016.82-90","url":null,"abstract":"Background: Malignant tumors arising from peripheral nerves or displaying differentiation along the lines of the various elements of the nerve sheath are referred to Malignant peripheral nerve sheath tumors (MPNST) and also called malignant schwannomas or neurofibrosarcomas. The common sites of involvement are head, neck, extremities and thorax. This case was discussed due to its rare incidence, namely less than 5% of soft tissue malignant tumor. The overall five year survival rate is approximately 50% in patients with resectable tumor. Case: We report a case of MPNST arising from mediastinum, the patient was a male, 41-years-old, with chief complaint are chest pain and mass in the back. Contrast enhanced chest CT Scan showed a solid mass (10.02 × 6.97 × 10.53 cm) in the right side of the posterior mediastinum. On microscopic examination with hematoxylin eosin imunostaining, of the mass on mediastinum showed typical features of MPNST, which were positive for S-100 imunostaining. Based on convensional histopathologic and imunostaining, this case was concluded as Malignant peripheral nerve sheath tumors (MPNST). Conclusion: The treatment of chest wall MPNSTs is multimodality, including wide local excision, adjuvant radiotherapy, and chemotherapy. In our case, we performed direct excision due to the infiltrating mass to the surrounding tissue, so the prognosis for this case was good. This case indicates the role of chemotherapy in treatment of advanced MPNST. Studies shows the superiority of the doxorubicin–ifosfamide regimen. As in this case the patient showed complete respons after surgery and adjuvant chemotherapy.","PeriodicalId":328612,"journal":{"name":"Jurnal Respirasi","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132203324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

POTT’S Disease 脊椎结核病

Jurnal Respirasi Pub Date : 2019-04-02 DOI: 10.20473/JR.V2-I.3.2016.99-109

Tutik Kusmiati, Hapsari Paramita Narendrani

{"title":"POTT’S Disease","authors":"Tutik Kusmiati, Hapsari Paramita Narendrani","doi":"10.20473/JR.V2-I.3.2016.99-109","DOIUrl":"https://doi.org/10.20473/JR.V2-I.3.2016.99-109","url":null,"abstract":"Pott's disease, sometimes reffered to tuberculous spondylitis, is an infection of tuberculosis that affects one or more vertebrae, which first described by Percival Pott. Tuberculous spondylitis is the most dangerous form of musculoskeletal tuberculosis because it can cause bone destruction, deformity and paraplegia. The spine is the most commonly affected due to bony dissemination of tuberculosis in bones. The deployment through the arteries, veins via Batson plexus and percontinuitatum by the spread of abscess paravertebral. The spread of tuberculosis infection will cause inflammation in paradiscs, and causes progressive bone destruction and then will make vertebral collapse and deformity arising shaped kyphosis (posterior angulation) called gibbus. Early diagnosis is often difficult, MRI is the best diagnostic tools for pott's disease. Tissue culture or spesimen of M. tuberculosis important to confirm the diagnosis. Medical treatment is preferred, whereas surgical therapy as a complements. Drop out of anti-tuberculous drugs is a major challenge for the treatment of spinal TB with MDR because of long duration of therapy and the cost. The prognosis for spinal TB increases with early diagnosis and rapid intervention.","PeriodicalId":328612,"journal":{"name":"Jurnal Respirasi","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114330170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Seorang Penderita Siliko Tuberkulosis dengan Penyulit Pneumotoraks 患有二氧化氮硅胶的结核病患者

Jurnal Respirasi Pub Date : 2019-04-02 DOI: 10.20473/JR.V2-I.3.2016.76-81

Winariani Koesoemoprodjo, Vinodini Merinda

{"title":"Seorang Penderita Siliko Tuberkulosis dengan Penyulit Pneumotoraks","authors":"Winariani Koesoemoprodjo, Vinodini Merinda","doi":"10.20473/JR.V2-I.3.2016.76-81","DOIUrl":"https://doi.org/10.20473/JR.V2-I.3.2016.76-81","url":null,"abstract":"Background: Silicosis is a lung disease caused by the work because of respirable crystalline silica. Often occurs in workers mining gold, iron, tin, granite, sandstone, slate, foundries, cement, ceramics and glass. The risk of silicosis develop into lung tuberculosis (TB) is higher than patients without silicosis. Another complication of silicosis is secondary spontaneous pneumothorax. Case : A man, 45 years old with a history of work as a bricklayer for 5 years with complaints shortness of breath since three days before admitted to the hospital, chest pain in the right hemithorax, and had chronic cough. Patients is on ATD therapy. From radiographic there is collapse lung, it was shown collapse line on the right hemithorax, and fibroinfiltrat with multiple cavities on both hemithorax. Patients then got chest tube insertion and evaluation for 3 weeks, but the lung has not expanded. From thoracoscopy, there is fibrotic band on the pleural space with conclution right trapped lung. From forcep biopsy on visceral pleura showed a widened alveolar epithelial layer coated with a pile of inflammatory lymphocytes and dust pigments. From broncoscopy, there is chronic lung inflamation. Spectrophotometric analysis from BAL specimens results showed a silica content of 4.25 ppm SiO2 from left BAL an 14.34 ppm SiO2 on the right BAL. Furthurmore, this patient got pleurodesis using betadine agent and continue the ATD. Evaluation the lung is fully expanded. Conclusion : This case illustrates the secondary spontaneous pneumothorax as a complication of silicotuberkulosis. No drug has proven effective for silicosis. Treatment is aimed to the disease complications that occur, in this case is secondary spontaneous pneumothorax and lung TB. Prevention at workplaces that have a risk of silicosis is very important.","PeriodicalId":328612,"journal":{"name":"Jurnal Respirasi","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121003499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Peran Imunitas Mukosa terhadap Infeksi Mycobacterium Tuberculosis 黏膜对结核病感染的影响

Jurnal Respirasi Pub Date : 2019-04-02 DOI: 10.20473/JR.V2-I.2.2016.61-68

Irmi Syafa’ah, Resti Yudhawati

引用次数: 1

Perubahan Fungsi Paru Pada Usia Tua 老年肺功能改变

Jurnal Respirasi Pub Date : 2019-04-02 DOI: 10.20473/JR.V3-I.2.2017.52-57

Helmi Hasan, Rena Arusita Maranatha

{"title":"Perubahan Fungsi Paru Pada Usia Tua","authors":"Helmi Hasan, Rena Arusita Maranatha","doi":"10.20473/JR.V3-I.2.2017.52-57","DOIUrl":"https://doi.org/10.20473/JR.V3-I.2.2017.52-57","url":null,"abstract":"Aging causes many changes in biological processes characterized by progressive and widespread changes associated with increased susceptibility to various diseases. Aging is not a homogeneous process. In contrast, human organs aging at different rates are affected by several factors, including genetic factors, lifestyle, and environmental exposure. Healthy aging remains accompanied by some morphological and functional changes in the respiratory system. During the first two decades of life, the lungs undergo a phase of growth and maturation. Respiratory system achieves maximum function at the age of 20 years for women and 25 years for men. Throughout the rest of life, aging is associated with a progressive decline in pulmonary performance and function. The normal aging of the respiratory system is associated with structural and functional decline in the respiratory system, resulting in increased respiratory work compared to younger subjects and is associated with reduced reserves in cases of acute illness, such as heart failure, infection, or airway obstruction. Pulmonary function decreases slowly throughout life even in healthy people. Disabilities and diseases related to aging are a global problem due to the longevity of life expectancy. An increased proportion of the elderly population is a challenge for doctors because of the clinical complexity of the elderly. A better understanding of change can help diagnose and treat lung disease in the elderly population.","PeriodicalId":328612,"journal":{"name":"Jurnal Respirasi","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122768113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

Problem Penegakkan Diagnostik Pasien dengan Massa di Paru 病人肺部有质量的诊断问题

Jurnal Respirasi Pub Date : 2019-04-02 DOI: 10.20473/JR.V3-I.2.2017.41-46

Laksmi Wulandari, Nikson Eduard Faot

{"title":"Problem Penegakkan Diagnostik Pasien dengan Massa di Paru","authors":"Laksmi Wulandari, Nikson Eduard Faot","doi":"10.20473/JR.V3-I.2.2017.41-46","DOIUrl":"https://doi.org/10.20473/JR.V3-I.2.2017.41-46","url":null,"abstract":"Background: Lung cancer are divided into 2 groups; i.e. Small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC). About 30% of NSCLC is squamus cell carcinoma and the other is adeno carcinoma. Late diagnosis makes such a high mortality rate. Early diagnosis plays a very important role in the management of therapy. Case: Patients complain of chronic cough more than 6 months, decreased appetite and weight loss. Chest X-ray and CT scan show a density of round shape mass, with firm border and smooth regular edge, also lympnodes enlargement (T2N2Mx) stage IIb. Appearance of lung mass is benign according to clinically and radiologically. FNAB-CT Guiding results are difference each time examination. The first result is squamous cell carcinoma but the last result is teratoma. Discussion: Based on the multidisciplinary discussion on Tumor Board Meeting, the diagnosis was decide as Squamous cell Carcinoma. The choice management of stage IIb lung cancer is surgery (Lobectomy). Histopathology finding post surgery is a Squamus Cell Carcinoma. Patients were then given adjuvant chemotherapy for 4 cycles with Platinum Base regimen paxuscarboplatin with the aim of clearing micrometastase that may still be left behind. The complete respons of platinum based chemotherapy following surgery in early stage of squamous cell carcinoma. Conclusion: Difficulties of lung cancer diagnostic are still the problem in the management of lung mass. Difference of diagnostic makes difference treatment choice. Multidiscipline discussion is needed to decide the diagnostic and treatment judgment.","PeriodicalId":328612,"journal":{"name":"Jurnal Respirasi","volume":"1076 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132947372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Organic Dust Toxic Syndrome (ODTS) 有机粉尘中毒综合症(ODTS)

Jurnal Respirasi Pub Date : 2019-04-02 DOI: 10.20473/JR.V2-I.1.2016.24-28

D. Bachtiar, A. Susanto

引用次数: 0

Tumor Mediastinum Anterior ( Yolk Sac Tumor ) pada Seorang Laki-Laki Dewasa Muda: Sebuah Kasus yang Jarang 老年男性的额菌丝肿瘤(约尔克萨克肿瘤):这是一个罕见的病例

Jurnal Respirasi Pub Date : 2019-04-02 DOI: 10.20473/JR.V2-I.2.2016.45-51

Risnawati Risnawati, Laksmi Wulandari

{"title":"Tumor Mediastinum Anterior ( Yolk Sac Tumor ) pada Seorang Laki-Laki Dewasa Muda: Sebuah Kasus yang Jarang","authors":"Risnawati Risnawati, Laksmi Wulandari","doi":"10.20473/JR.V2-I.2.2016.45-51","DOIUrl":"https://doi.org/10.20473/JR.V2-I.2.2016.45-51","url":null,"abstract":"Background: Primary mediastinal yolk sac tumor is an extremely rare and highly malignant tumors occuring in children and young adult. They are more common in men. The most common symptoms on ptesentation were dyspnea, chest pain, cought, fever, night sweat, or weight loss. Primary mediastinal tumor are considered to have poor prognosis. Case: A 18- year-old man who presented with shorthness of breath, chest pain, fever, night sweat, and generalized weakness. He had no significant surgical, familiy or social history. The chest X-Ray and computed tomographic scan of the chest showed a large anterior mediasti nal mass. The serum level of alpha- fetoprotein and β-HCG was elevated. The histological examination revealed the finding of yolk sac tumor. This supported the diagnosis of yolk sac tumor. The patient received a combination chemotherapy consisting of cisplatin, etoposide and bleomycin every 3 weeks for total of 4 cycles. Conclusions: Primary mediastinal yolk sac tumor is a rare tumor. The diagnosis should be made not only by morphological studies but the also the patients age and the elevation of serum alpha-fetoprotein. In spite of modern chemotherapy, the prognosis of mediastinal yolk sac tumor remains poor.","PeriodicalId":328612,"journal":{"name":"Jurnal Respirasi","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126488771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Seorang Penderita dengan Retrosternal Goiter Goiter患者

Jurnal Respirasi Pub Date : 2019-04-02 DOI: 10.20473/JR.V2-I.1.2016.14-23

M. Mawardi, Daniel Maranatha

引用次数: 0