Mhasisielie Zumu, R. S. Arun, Nageswara Rao, S. K. Kumar, Nayan Sri, Vaibhav Tirupati
{"title":"Complications of Forgotten or Neglected Biliary Plastic Stents and Their Outcome","authors":"Mhasisielie Zumu, R. S. Arun, Nageswara Rao, S. K. Kumar, Nayan Sri, Vaibhav Tirupati","doi":"10.4103/ghep.ghep_5_24","DOIUrl":"https://doi.org/10.4103/ghep.ghep_5_24","url":null,"abstract":"\u0000 \u0000 Before cholecystectomy, endoscopic retrograde cholangiopancreatography (ERCP) with common bile duct (CBD) stent placement is the standard therapy for choledocholithiasis. Prolonged stents in situ may present with various complications, some of which may be life-threatening.\u0000 \u0000 \u0000 \u0000 A study in a tertiary center in South India from January 2018 to July 2023. A total of 624 patients underwent ERCP for biliary stent procedures, out of which 29 had biliary plastic stents in situ for more than 6 months. We retrospectively analyzed these 29 cases for complications and their treatment outcomes.\u0000 \u0000 \u0000 \u0000 The mean ± standard deviation age was 57.5 ± 16.6 years, male-to-female ratio was 2.2:1, 55.17% had a cholecystectomy (n = 16), the most common indications for CBD stent placement were choledocholithiasis 75.8% (n = 22); the median duration of stent in situ was 7 months interquartile range (6–9). The reasons for delayed CBD stent removal were: 27.6% due to the COVID-19 pandemic (n = 8), 13.8% surgically unfit (n = 4), 6.9% financial constraints (n = 2), 3.4% of patients were unaware of the stent in situ (n = 1), and 48.3% were unknown (n = 14). The complications associated were that 69% had calculi/sludge (n = 20), 24.14% had cholangitis (n = 7), 7% were asymptomatic (n = 2), and 3% had intestinal perforation (n = 1).\u0000 \u0000 \u0000 \u0000 Early complication identification and treatment lead to successful clinical outcomes. Irrespective of cholecystectomy, a check cholangiogram, and CBD clearance should be done in all cases of biliary stent removal.\u0000","PeriodicalId":328017,"journal":{"name":"Gastroenterology, Hepatology and Endoscopy Practice","volume":"106 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141389106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Abstracts of Case Reports Presented at the Mid-term Meeting of the Tamil Nadu Chapter of Indian Society of Gastroenterology at Puducherry on 23rd September 2023","authors":"","doi":"10.4103/ghep.ghep_34_23","DOIUrl":"https://doi.org/10.4103/ghep.ghep_34_23","url":null,"abstract":"","PeriodicalId":328017,"journal":{"name":"Gastroenterology, Hepatology and Endoscopy Practice","volume":"243 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139152742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An Unusual Cause for Sudden Massive Hematochezia in Intensive Care Unit","authors":"U. S. Manmohan, R. S. Arun, Aditi Damle","doi":"10.4103/ghep.ghep_20_23","DOIUrl":"https://doi.org/10.4103/ghep.ghep_20_23","url":null,"abstract":"Gastrointestinal (GI) mucormycosis is a life-threatening infection caused by fungi of the subphylum Mucoromycotina, order Mucorales. GI mucormycosis is rarely seen in immunocompetent patients. The symptoms of GI mucormycosis are varied and depend on the affected site. Nonspecific abdominal pain and distention associated with nausea and vomiting are the most common symptoms. They rarely presents as hematochezia.","PeriodicalId":328017,"journal":{"name":"Gastroenterology, Hepatology and Endoscopy Practice","volume":"120 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139149181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Balamurali Rangachari, Manimaran Murugesan, Chitra Shanmugam, S. Gopalsamy, K. Chinnadurai
{"title":"Indian Literature Review on Nonalcoholic Fatty Liver Disease","authors":"Balamurali Rangachari, Manimaran Murugesan, Chitra Shanmugam, S. Gopalsamy, K. Chinnadurai","doi":"10.4103/ghep.ghep_23_23","DOIUrl":"https://doi.org/10.4103/ghep.ghep_23_23","url":null,"abstract":"Nonalcoholic fatty liver disease (NAFLD) is currently the most common chronic liver disease worldwide. The global prevalence of NAFLD has increased from 25.3% in 1990–2006 – 38.0% in 2016–2019. Easy access to calorie-dense food and a sedentary lifestyle together with the modern epidemics of diabetes mellitus and obesity have catapulted NAFLD into a substantial public health problem in India as in other parts of the world. NAFLD has emerged as one of the leading causes of hepatocellular carcinoma and liver transplant in India. In this review, we summarized the Indian perspective of NAFLD epidemiology, risk factors, assessment, spectrum, lifestyle interventions, treatment options, and transplant prospects.","PeriodicalId":328017,"journal":{"name":"Gastroenterology, Hepatology and Endoscopy Practice","volume":"43 21","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139151413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Abstracts Presented at the Mid-term Meeting of the Tamil Nadu Chapter of the Indian Society of Gastroenterology at Puducherry on September 23, 2023","authors":"","doi":"10.4103/ghep.ghep_33_23","DOIUrl":"https://doi.org/10.4103/ghep.ghep_33_23","url":null,"abstract":"","PeriodicalId":328017,"journal":{"name":"Gastroenterology, Hepatology and Endoscopy Practice","volume":"63 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139150341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B. Vijayalekshmi, ThomasA Kodiatte, G. Amirtharaj, Pamela Christudoss, U. Zachariah, A. Nellickal, B. Ramakrishna, K. A. Balasubramanian, C. Eapen, Ashish Goel
{"title":"Rhodanine Stain Improves Utility of Leipzig Score to Diagnose Hepatic Wilson’s Disease in Noncholestatic Patients with Fibrosis","authors":"B. Vijayalekshmi, ThomasA Kodiatte, G. Amirtharaj, Pamela Christudoss, U. Zachariah, A. Nellickal, B. Ramakrishna, K. A. Balasubramanian, C. Eapen, Ashish Goel","doi":"10.4103/ghep.ghep_22_23","DOIUrl":"https://doi.org/10.4103/ghep.ghep_22_23","url":null,"abstract":"Cholestasis may increase the difficulty of diagnosing Wilson’s disease (WD). We aimed to compare Leipzig score including hepatic parenchymal copper concentration or rhodanine stain, to diagnose hepatic WD, in noncholestatic patients with fibrosis. We defined cholestasis by biochemical and/or histological criteria. Of noncholestatic patients who had liver fibrosis and liver copper estimation, those with isolated hepatic WD comprised WD study group and those with liver disease other than WD, with either low serum ceruloplasmin, high urinary copper, or Kayser–Fleischer ring, were controls. WD diagnosis by Leipzig score was labeled highly likely, probable, or unlikely. Twenty WD study group patients (12 males; 21 [6–52] years; median [range]) and 18 controls (13 males; 32 [10–69] years, all had high urinary copper) were recruited. Rhodanine stain was positive in 60% WD patients and in 33% of controls. With rhodanine stain, Leipzig score had sensitivity of 100% (95% confidence interval: 83.2%–100%), specificity of 66.7% (41%–86.7%), and positive likelihood ratio of 3 (1.56–5.77) to diagnose probable/highly likely WD. In contrast, on adding hepatic parenchymal copper concentration, Leipzig score had sensitivity of 100% (83.2%–100%), but specificity was 38.9% (17.3%–64.2%). In controls, Leipzig score (including rhodanine stain) of ≤ 2 ruled out WD. On excluding cholestatic patients, rhodanine stain performs better than hepatic parenchymal copper concentration to diagnose hepatic WD using Leipzig score in patients with fibrosis. Widespread availability is an added advantage of rhodanine stain.","PeriodicalId":328017,"journal":{"name":"Gastroenterology, Hepatology and Endoscopy Practice","volume":"59 51","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139150650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Diagnosis and Management of Esophageal Motility Disorders Beyond Achalasia","authors":"Mayank Jain","doi":"10.4103/ghep.ghep_25_23","DOIUrl":"https://doi.org/10.4103/ghep.ghep_25_23","url":null,"abstract":"High-resolution esophageal manometry (HREM) is the gold standard for the diagnosis of esophageal motility disorders. Achalasia cardia has been the most extensively studied esophageal motility disorder. However, nonachalasia esophageal motility disorders are common too. The present review highlights the diagnosis and management strategies for these disorders. HREM needs to be complemented with clinical symptoms and timed barium esophagogram/functional lumen imaging probe to properly diagnose spastic and hypomotility disorders. Use of Indian normative values is essential to identify patients with these motility disorders accurately. Adjunctive tests such as multiple rapid swallows and rapid drink challenge increase the diagnostic accuracy of HREM studies. HREM is mainly useful in reflux patients with refractory symptoms and for preoperative assessment. Its role in postsurgical cases is evolving.","PeriodicalId":328017,"journal":{"name":"Gastroenterology, Hepatology and Endoscopy Practice","volume":"71 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139151749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Sarangapani, Tarun J. George, Nawahirsha Sultan, S. Malathi
{"title":"Rescue Therapy in Gastric Mucosal Bleed using Haemospray™","authors":"A. Sarangapani, Tarun J. George, Nawahirsha Sultan, S. Malathi","doi":"10.4103/ghep.ghep_19_23","DOIUrl":"https://doi.org/10.4103/ghep.ghep_19_23","url":null,"abstract":"Hemostatic agents are used extensively in endoscopic management of gastrointestinal (GI) bleed. Conventional endoscopic techniques such as thermal, mechanical (clipping), and injection treatment fail in up to 5%–10%. These agents are used particularly in anatomically challenging areas, lesions with poor visibility, diffuse bleeding, and friable tissues. We present an endoscopic management of gastric bleed in a 17-year-old male with leukemia (early T-cell precursor acute lymphoblastic leukemia), who underwent haplotransplant. Posttransplant patient developed pneumonia with acute respiratory distress syndrome requiring extracorporeal membrane oxygenation support with multiorgan dysfunction syndrome, graft versus host disease. During his hospital stay, he developed persistent GI bleed from multiple large excavating gastric ulcers. Multiple sessions of conventional hemostatic endoscopic procedures such as hemoclips, glue injection, and sclerosants failed to achieve hemostasis. Mucosal surface bleeds are difficult to manage hence we used Hemospray for achieving good hemostasis.","PeriodicalId":328017,"journal":{"name":"Gastroenterology, Hepatology and Endoscopy Practice","volume":"298 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139152500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Endoscopy in the Diagnosis and Management of Gastrointestinal Neuroendocrine Tumors","authors":"Noble Varghese Mathews, S. Chowdhury, Anoop John","doi":"10.4103/ghep.ghep_21_23","DOIUrl":"https://doi.org/10.4103/ghep.ghep_21_23","url":null,"abstract":"Gastrointestinal neuroendocrine tumors (GI NETs) are considered rare neoplasms that arise from enterochromaffin cells which form a part of the neuroendocrine cell system present throughout the GI tract. Although considered a rare tumor, its prevalence has increased significantly in recent years owing to the increase in the number of endoscopic evaluations, advanced imaging modalities, and greater detection of the entity by pathologists. The role of an endoscopist remains pivotal in diagnosing and managing GI NETs, ranging from tumor detection, sampling, characterization, and staging which forms the basis of oncological evaluation, particularly of those involving the stomach, duodenum, and colorectum. Endoscopic therapy can provide curative resection of tumors and surveillance scopies in a minimally invasive fashion owing to lesser patient morbidity. Our review aims to provide an overview of the role of the gastroenterologist in diagnosing and managing GI NETs.","PeriodicalId":328017,"journal":{"name":"Gastroenterology, Hepatology and Endoscopy Practice","volume":"308 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139152578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mhasisielie Zumu, Ilavarasi Lakshmanan, R. S. Arun, Aditi Damle
{"title":"Primary Gastric Actinomycosis: Case Reports and Literature Review","authors":"Mhasisielie Zumu, Ilavarasi Lakshmanan, R. S. Arun, Aditi Damle","doi":"10.4103/ghep.ghep_35_23","DOIUrl":"https://doi.org/10.4103/ghep.ghep_35_23","url":null,"abstract":"Primary Gastric Actinomycosis is extremely rare. We report two cases of Primary Gastric Actinomycosis. First case, a 90-year-old gentleman with multiple co-morbidities came with post prandial non radiating epigastric pain for 2 weeks. Gastroscopy showed a submucosal gastric SOL. Endoscopic ultrasonography-guided Gastric SOL aspiration grew Actinomyces naeslundii. Second case, a 56 year old gentleman, known diabetic came with abdominal pain for 5 to 6 months and weight loss. Ultrasound abdomen revealed pyloric thickening. Upper gastrointestinal endoscopy showed gastric ulcer. Biopsies were suggestive of Actinomycosis. Cautious used of long term proton pump inhibitor in elderly and immunosuppressed individual. All efforts should be made to acquire the appropriate tissue sample for histopathology examination and culture. All actinomycosis infections need not have Sulphur pigments. Actinomycosis has a good prognosis with appropriate treatment.","PeriodicalId":328017,"journal":{"name":"Gastroenterology, Hepatology and Endoscopy Practice","volume":"47 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139149680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}