Santosh University Journal of Health Sciences最新文献

{"title":"Study of the lipid and lipoprotein activity in various grades of untreated hypertension","authors":"S. Bansal, Ashok Kumar, Tanzeel Wani, Tanuraj Tyagi","doi":"10.4103/2455-1732.331798","DOIUrl":"https://doi.org/10.4103/2455-1732.331798","url":null,"abstract":"Introduction: Hypertension is an important medical and public health problem both in developed and developing countries. Abnormalities in serum lipid levels (dyslipidemia) are recognized as a major risk factor for cardiovascular disease (CVD) and essential hypertension. Lipid profile is earliest marker for coronary heart disease and includes total cholesterol (TC), high-density lipoprotein-cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), triglycerides (TG), and very LDL (VLDL). The role of lipoprotein (a) (Lp[a]) as an independent biomarker of vascular disease risk has been investigated for more than 20 years, but recently the European Atherosclerosis Society has issued a new consensus statement endorsing routine measurement of Lp(a) among patients with moderate-to-high-risk CVD. The aim of the study is to find out lipid profile and lipoprotein activity in various grades of untreated hypertension. Materials and Methods: This was a cross-sectional study conducted at a tertiary care setting in Ghaziabad. The study was conducted from February 2017 to February 2018 and 125 subjects were included after the detailed history, physical examination, and inclusion and exclusion criteria. All patients were evaluated for their lipid profile along with Lp(a) and other routine investigations. Results: There was a statistically significant rising level on TC, TG, LDL, VLDL, and Lp(a) (P ≤ 0.0001) excluding HDL statistically not significant (P = 0.343). This study showed that lipid and lipoprotein cholesterol abnormalities exist and even worsen with severity of hypertension. It is important that investigations in patients with hypertension should include lipid profile and lipoprotein. Conclusion: Serum lipid profile can serve as an important marker for screening hypertensive patients for CVD and their early detection can reduce cardiovascular morbidity and mortality. In this study, TC, LDL-C, TG, VLDC-C, Lp(a), and body mass index were found to be abnormal in hypertensive patients, but HDL-C did not show any significant variation with hypertension.","PeriodicalId":326476,"journal":{"name":"Santosh University Journal of Health Sciences","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114993317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dermatosis neglecta mimicking macular amyloidosis","authors":"P. Yadav, A. Yadav, S. Agarwal","doi":"10.4103/2455-1732.331784","DOIUrl":"https://doi.org/10.4103/2455-1732.331784","url":null,"abstract":"Few cases of dermatosis neglecta have been reported in the medical literature, although the diagnosis is well-known to dermatologists. It is characterized by dirty brown-grey cutaneous patches and plaques that can simply be eradicated by rubbing with alcohol pads. In most of the cases, it is associated with a local pathology due to which the patient is afraid to clean the area or any debilitating systemic illness which makes the patient incapable of proper cleansing. Herein, we present a mentally normal, obese male with reticulate hyperpigmentation involving the mid scapular region mimicking macular amyloidosis without any underlying local pathology which turned out to be dermatosis neglecta.","PeriodicalId":326476,"journal":{"name":"Santosh University Journal of Health Sciences","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131280008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical management of carcinoma of buccal mucosa abutting mandible and involving skin of the face: A case report","authors":"G. Mittal, T. Bhagat, Shalabh Gupta, S. Sharma, Nithin Pillai","doi":"10.4103/2455-1732.331783","DOIUrl":"https://doi.org/10.4103/2455-1732.331783","url":null,"abstract":"Squamous cell carcinoma (SCC) of the oral cavity is the most common site of head-and-neck carcinoma in India. It grows in the vicinity and penetrates through adjacent anatomical structures; surgical resection of the tumor becomes more challenging in the head-and-neck region. As important anatomical structures are closely packed and to resect the tumor with safe margins being an issue, thus raising specific considerations for reconstruction relative to the extent of resection. The present case describes the management of a 64-year-old man with SCC of the left buccal mucosa, invaded into the skin of the cheek. It was managed surgically, with resection and flap reconstruction in the same sitting done in Santosh Medical College and Hospital, Ghaziabad.","PeriodicalId":326476,"journal":{"name":"Santosh University Journal of Health Sciences","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114620171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vitamin D in defense against the terrorism of coronavirus disease 2019: A meta-analysis","authors":"Preeti Sharma, Trpta Bhagat, B. Sharma, P. Kumar","doi":"10.4103/2455-1732.331791","DOIUrl":"https://doi.org/10.4103/2455-1732.331791","url":null,"abstract":"Background: Coronavirus disease 2019 (COVID-19) pandemic was also spread during winter time in December from Wuhan the city of China to worldwide. Various studies conducted throughout the world have indicated the possible relationship between Vitamin D and COVID-19 infection. Aim: This narrative review is designed to support Vitamin D role and its efficacy in managing COVID-19 menace. Materials and Methods: Latest 50 articles for Vitamin D, and COVID-19 relationship and management were scrutinized to summarize this article from data bases of PubMed and Google scholar in English language. Diagrams were created by biorender.com to summarize pictorial relations. Conclusions: Higher mortality is associated with countries of high-level Vitamin D deficiencies. Many studies have found a significant relation between Vitamin D deficiency and COVID-19 complications and related comorbidities. It is highly supported by many literature to recommend daily dose of Vitamin D3 10,000 IU/day for a few weeks to rapidly increase 25-hydroxyvitamin D levels above 40–60 ng/mL, in population at higher risk.","PeriodicalId":326476,"journal":{"name":"Santosh University Journal of Health Sciences","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128325168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nanotechnology in periodontics: A review","authors":"Deepali Singhal, Priyanka Aggarwal, S. Bali, Kirti Pal","doi":"10.4103/2455-1732.331785","DOIUrl":"https://doi.org/10.4103/2455-1732.331785","url":null,"abstract":"Nanotechnology or nanoscience is the research and development of an applied science at the atomic, molecular, or macromolecular levels (i.e., molecular engineering and manufacturing). Periodontitis is one of the most common diseases involving tooth and it's supporting structures. Management of which is important for improving the quality of life of the patient that has it's impact on the overall health of an individual. With upsurge of various treatment methodologies for the treatment of periodontitis, nanotechnology has evolved as a promising mode of treatment. Applications of nanotechnology in medical and dental fields have only approached the horizon with opportunities and possibilities for the future that can only be limited by our imagination. This paper provides an early glimpse of nanotechnology applications in dentistry and also illustrates the potential of different nanomaterials and their impact on clinical practice.","PeriodicalId":326476,"journal":{"name":"Santosh University Journal of Health Sciences","volume":"65 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133302966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of post-COVID 19 symptoms: An observational cohort study from a level 3 COVID hospital","authors":"P. Saxena, Eshutosh Chandra, S. Sahay, C. Mahendran, Pooja Das, Jijo Jose, B. Reddy, S. Sivaji","doi":"10.4103/2455-1732.331794","DOIUrl":"https://doi.org/10.4103/2455-1732.331794","url":null,"abstract":"Introduction: A substantial number of patients continue to have symptoms even after testing negative for COVID 19. Ours is a single-center, observational, cross-sectional study that describes the prevalent symptoms in patients who have recovered from mild-to-moderate COVID 19 disease. Materials and Methods: In a span of 3 months, from November 2020 to January 2021, we collected self-reported data from all post-COVID patients who consulted the post-COVID 19 outpatient department. Data on the pertinent history related to their diagnosis of COVID-19 disease like the date of reverse transcriptase-polymerase chain reaction positive and negative reports and length of stay in hospital were collected. Self-reported data were collected in simple Yes/No format for the presence of common respiratory and general post-COVID-19 symptoms. The final data were analyzed and presented using the using R software version 4.0.2. Results: The mean age of the patients was 42.89 years with majority being from the age group of above 50 years of age. The mean duration of hospital stay was found to be 14 ± 7 days. A higher percentage were admitted for >10 days among all age groups, more predominantly among >60 years of age. Only 5 male patients gave a history of receiving noninvasive ventilation. Significantly a greater number of females complained of fatigue. Other symptoms that were found more commonly in females were headache, loss of hearing, and wheeze. Conclusion: In our study, fatigue is the most common presenting symptoms followed by cough and breathlessness. Further evaluation and regular follow-up required to substantiate this observation.","PeriodicalId":326476,"journal":{"name":"Santosh University Journal of Health Sciences","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124849814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Caudal anesthesia for hemorrhoidectomy in a patient with ankylosing spondylitis: A case report","authors":"Mahima Lakhanpal, Ritesh Kumar, Ishan Yadav, D. Sarkar, Ankita Aggarwal","doi":"10.4103/2455-1732.331788","DOIUrl":"https://doi.org/10.4103/2455-1732.331788","url":null,"abstract":"Ankylosing spondylitis has always been a challenge to anesthesiologists due to its multisystem involvement. Both airway management and regional anesthesia administration is quite difficult as vertebral and ligaments fusion makes spine stiff and neck movements difficult. We report a case of a 42-year-old male posted for hemorrhoidectomy with a stiff spine and negligible neck movement. The successful caudal epidural block was administered after failure to reach subarachnoid space in multiple attempts.","PeriodicalId":326476,"journal":{"name":"Santosh University Journal of Health Sciences","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127229830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Significance of surgical margins assessment in head-and-neck squamous cell carcinoma: A surgeon's perspective","authors":"Sanjeev Tomar, Upma Tomar, A. Mediratta, M. Gupta, Shivani Bhandari","doi":"10.4103/2455-1732.331796","DOIUrl":"https://doi.org/10.4103/2455-1732.331796","url":null,"abstract":"Head-and-neck squamous cell carcinoma (HNSCC) is the most common malignant tumor of the oral cavity. HNSCC can be treated by surgery, radiation therapy, chemotherapy and sometimes combinations of all these modalities, and among all these modalities, surgery is the most accepted line of treatment. The purpose of cancer surgery is achieving complete resection of the tumor, and its success depends on not leaving any residual neoplastic cell. Despite all the recent advances in the diagnosis and treatment of these patients, HNSCC is showing increasingly high recurrence rates. The surgical margins (SMs) or resection margins are the margins or boundaries of resection specimen, which is excised by the surgeon. The goal of this review was to evaluate the significance of SMs in adequate and proper treatment of HNSCC along with minimum recurrence.","PeriodicalId":326476,"journal":{"name":"Santosh University Journal of Health Sciences","volume":"62 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130465713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of working memory as a significant determinant of academic performance","authors":"Mathew Varghese, S. Padma Rani, A. Nair","doi":"10.4103/2455-1732.331793","DOIUrl":"https://doi.org/10.4103/2455-1732.331793","url":null,"abstract":"Context: Working memory plays a crucial role in determining the overall academic performance of a child irrespective of whether the child is learning disabled or not. Aims: The aim of the study is to explore the cognitive profile of the three categories of children: specific learning disability (SLD), Non-learning disabled (NLD), and scholastically poor children. Settings and Design: In the present study, three groups of children in the age range of 8–11 years studying in three to seventh standard, were selected as the sample for the study. Subjects and Methods: The three categories of children selected are SLD children, NLD children, and children who are scholastically poor. The three categories of children were administered with the Wechsler Intelligence Scale for Children-IV (Indian adaptation) test to analyze the cognitive profile. The cognitive pattern of each group is analyzed and compared. Statistical Analysis: Independent sample t-test was used for statistical analysis. Results and Conclusions: The results show that there is a gross and specific deficit in the domain of working memory among the SLD and scholastically poor children, which indicates that working memory plays a determining role in academic performance.","PeriodicalId":326476,"journal":{"name":"Santosh University Journal of Health Sciences","volume":"60 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125795867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Post-COVISHIELD™ vaccination symptoms among health-care workers – A multicentric survey","authors":"Mahima Lakhanpal, Ritesh Kumar, D. Sarkar","doi":"10.4103/2455-1732.331789","DOIUrl":"https://doi.org/10.4103/2455-1732.331789","url":null,"abstract":"","PeriodicalId":326476,"journal":{"name":"Santosh University Journal of Health Sciences","volume":"154 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116541068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}