Davy Bailey, Paula Kelly, Tom Iocono, Joe Sullivan, Pat Jackson, Wendy Swanson, Hollie Jicha, Greg Wilson, Melinda Springer, J. Stevens, Julia Valentino
{"title":"Basic Sciences","authors":"Davy Bailey, Paula Kelly, Tom Iocono, Joe Sullivan, Pat Jackson, Wendy Swanson, Hollie Jicha, Greg Wilson, Melinda Springer, J. Stevens, Julia Valentino","doi":"10.1515/jpme.2009.188","DOIUrl":"https://doi.org/10.1515/jpme.2009.188","url":null,"abstract":"Faculty Council chair status: Prior to the meeting, by electronic ballot, Kelly was elected Faculty Council Chair Pro Tem. Kelly will work with past Chair Springer and Michael Kilgore, who has indicated interest in serving as the next chair, pro tem, to maintain continuity in ongoing faculty council activities. A proposal to permit rotating chairs in the faculty council, as well as other options for chair service, will be presented to the COM faculty for consideration and subsequent vote at the December general faculty meeting.","PeriodicalId":324006,"journal":{"name":"Chronicle of Diabetes Research and Practice","volume":"297 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140283329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Dietary fiber in the management of type 2 diabetes mellitus: A narrative review","authors":"G. Dharmatti, Nidhi Singh, A. Ghag","doi":"10.4103/cdrp.cdrp_21_22","DOIUrl":"https://doi.org/10.4103/cdrp.cdrp_21_22","url":null,"abstract":"Type 2 diabetes mellitus (T2DM) has become a worldwide epidemic, especially in Asian countries as a result of rapid socioeconomic development, overnutrition, and lack of physical activity. Among the strategies for preventing and managing T2DM, the promotion of healthy dietary habits plays an important role. Various studies which were mainly carried out in Western countries showed that higher dietary fiber (DF) intake has a significant association with a lower risk of the development of T2DM. Thus, a narrative review concentrating on the macronutrient DF was performed. PubMed and Google Scholar were used for this purpose. The goal was to examine the most recent medical research on the advantages of DF for health, with a particular emphasis on how DF consumption affects glycemic management.","PeriodicalId":324006,"journal":{"name":"Chronicle of Diabetes Research and Practice","volume":"129 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115464078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Suganthi, Nupur Lalvani, G. Jevalikar, Archana Sarda, A. Unnikrishnan
{"title":"A practical approach to the diagnosis of type 1 diabetes: An Indian perspective","authors":"K. Suganthi, Nupur Lalvani, G. Jevalikar, Archana Sarda, A. Unnikrishnan","doi":"10.4103/cdrp.cdrp_19_22","DOIUrl":"https://doi.org/10.4103/cdrp.cdrp_19_22","url":null,"abstract":"There are more than 1 million people living with type 1 diabetes worldwide. People with classical type 1 diabetes are often, though not always young and require insulin therapy life long without which they are at risk of ketoacidosis. The proper and early diagnosis of type 1 diabetes is critical because of therapeutic implications and the prevention of diabetes-related complications. As the incidence of type 1 diabetes is increasing in India, and given unique socioeconomic challenges in the diagnosis and management of type 1 diabetes in India, it is important to approach the diagnosis from an Indian perspective. In this article, we discuss the practical aspect of clinical presentation and diagnosis of type 1 diabetes.","PeriodicalId":324006,"journal":{"name":"Chronicle of Diabetes Research and Practice","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126335231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Saurabh Kalamkar, Ashish Thorve, V. Gajjar, U. Divate, Sucheta Karandikar-Iyer, P. Goel, Y. Shouche, R. Ashma, S. Ghaskadbi
{"title":"Single nucleotide polymorphism in glutathione synthetase gene in Indian population with type 2 diabetes","authors":"Saurabh Kalamkar, Ashish Thorve, V. Gajjar, U. Divate, Sucheta Karandikar-Iyer, P. Goel, Y. Shouche, R. Ashma, S. Ghaskadbi","doi":"10.4103/cdrp.cdrp_6_23","DOIUrl":"https://doi.org/10.4103/cdrp.cdrp_6_23","url":null,"abstract":"Introduction: Our earlier study has confirmed the presence of significantly low glutathione (GSH) in individuals with type 2 diabetes. Low levels of GSH in addition to other factors can be due to the presence of single nucleotide polymorphism (SNP) in the gene glutathione synthetase (GSS). We have therefore checked the presence of SNPs in GSS, known to be associated with GSH deficiency, in the Indian population. Methods: Blood samples were collected from cases (people with diabetes) and controls (individuals without diabetes) for GSH estimation and DNA isolation. Amplicons obtained against selected exons of GSS after polymerase chain reaction amplification were sequenced and analyzed for the presence of SNPs. Results: A significantly low GSH was found in the case compared to control group (P < 0.001). However, we did not find any reported or novel SNPs associated with GSH deficiency in either of the groups. Conclusion: Data obtained suggest that the lower GSH found in individuals with diabetes of Indian origin is not contributed by SNPs in GSS reported otherwise in different population.","PeriodicalId":324006,"journal":{"name":"Chronicle of Diabetes Research and Practice","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126343755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Unnikrishnan, P. Dhore, G. Nazar, Vinay K. Gupta, M. Chopra, Aastha Chugh, Tina Rawal, Shalini Bassi, A. Bhatt, S. Deshpande, M. Arora
{"title":"Evaluation of the effect of project diabetes with dignity intervention on metabolic parameters among adults with diabetes in a rural Indian community","authors":"A. Unnikrishnan, P. Dhore, G. Nazar, Vinay K. Gupta, M. Chopra, Aastha Chugh, Tina Rawal, Shalini Bassi, A. Bhatt, S. Deshpande, M. Arora","doi":"10.4103/cdrp.cdrp_2_23","DOIUrl":"https://doi.org/10.4103/cdrp.cdrp_2_23","url":null,"abstract":"Introduction: Knowledge about diabetes and access to health care in rural Indian settings are inadequate. This study aims to compare the effects of community health worker–based intervention on the glycemic parameters of type 2 diabetes, in a rural population. Methods: Diabetes with dignity (DWD) was a community-based, quasi-experimental trial conducted with 416 adults (30–70 years) with diabetes. All villages under five sub-centers of two Primary Health Centers formed part of the study. Accredited Social Health Activists (ASHAs) conducted screening of high-risk adults in all villages and implemented a 6-month DWD intervention (counseling of people with diabetes/family; monthly house-to-house visits; community awareness-raising) in the intervention area. The changes in glycated hemoglobin A1c (HbA1C), lipid profile, urine micro-albumin, blood pressure, body mass index, and waist circumference between participants from baseline to the end of follow-up were assessed through laboratory/clinical examination. Results: Out of the 416 participants, 216 (52%) belonged to the intervention group. There was a significant decline of 6.4% in mean HbA1C in the intervention group (from 8.79 at baseline to 8.23 at the end of follow-up) and a 10.4% increase in the control group (8.75%–9.66%) (P = 0.010). There was a significant decline in mean low-density lipoprotein cholesterol values from baseline to the end of follow-up in the intervention group versus an increase in the control group (−2.29% vs. 12.4%; P = 0.005). Conclusion: Engaging ASHAs through intervention was effective in strengthening the health system and resulted in improved glycemic control. Capacity-building of ASHAs for the prevention and management of diabetes in rural community settings is recommended.","PeriodicalId":324006,"journal":{"name":"Chronicle of Diabetes Research and Practice","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123185044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Nondiabetic kidney disease in type 2 diabetes mellitus patients: The current need to look for new noninvasive biomarkers","authors":"Subhasis Neogi, Sujoy Ghosh","doi":"10.4103/cdrp.cdrp_5_23","DOIUrl":"https://doi.org/10.4103/cdrp.cdrp_5_23","url":null,"abstract":"","PeriodicalId":324006,"journal":{"name":"Chronicle of Diabetes Research and Practice","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115395715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shubhangi Tathare, Varsha Kumbhar, R. Panse, S. Kumaran, Shweta Deshmukh, A. Bidaye
{"title":"Examination of feet in people with diabetes: A guide for primary care physicians","authors":"Shubhangi Tathare, Varsha Kumbhar, R. Panse, S. Kumaran, Shweta Deshmukh, A. Bidaye","doi":"10.4103/cdrp.cdrp_11_22","DOIUrl":"https://doi.org/10.4103/cdrp.cdrp_11_22","url":null,"abstract":"Diabetic foot is a common complication of diabetes and leads to considerable morbidity and mortality. Neuropathy, deformity, infection and ischemia play a key role in the pathogenesis of diabetic foot ulcer. A multidisciplinary team approach by a nurse, physician, diabetic foot surgeon and the caregiver as well as close monitoring can prevent foot complications. Proper foot care, foot hygiene, annual foot examination and correct choice of footwear are main factors in preventing foot problems, ulceration and amputations. Physicians play a lead role in early detection and prevention of foot problems. This article will focus on how to perform foot examination in routine clinical practice.","PeriodicalId":324006,"journal":{"name":"Chronicle of Diabetes Research and Practice","volume":"136 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122851079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shweta Deshmukh, V. Purandare, Ashutosh Pakale, Ambika Unnikrishnan
{"title":"Insulin autoimmune syndrome: A report of two cases","authors":"Shweta Deshmukh, V. Purandare, Ashutosh Pakale, Ambika Unnikrishnan","doi":"10.4103/cdrp.cdrp_24_22","DOIUrl":"https://doi.org/10.4103/cdrp.cdrp_24_22","url":null,"abstract":"Insulin autoimmune syndrome (IAS), also known as Hirata's disease, is a rare endocrine disease. It is a form of autoimmune endogenous hyperinsulinemic hypoglycemia, which develops when genetically predisposed individuals get exposed to triggering factors such as viral infection or certain medications containing sulfhydryl groups. It is important to consider IAS in the differential diagnosis of hypoglycemia as its incidence seems to be increasing worldwide. In this article, we summarize a report of two cases of IAS and their clinical manifestations, biochemical characteristics, their step-by-step diagnosis, and also prompt utilization of continuous glucose monitoring system as a monitoring tool for appropriate management. The first patient who presented with hypoglycemic episodes had recently suffered from a viral pneumonia, which probably acted as a superantigen and triggered development of IAS. The second patient also had hypoglycemic episodes, which used to recover after intake of glucose-containing liquids. Alpha-lipoic acid containing multivitamin may have triggered the development of IAS in the second patient. The tests performed showed high serum insulin and C-peptide levels along with insulin autoantibody positivity confirming the diagnosis of Hirata's disease. Immunosuppression therapy was not required as both the patients responded well to diet modification and corticosteroid therapy. It is important to be mindful while prescribing alpha-lipoic acid-containing supplements though it has good antioxidant properties, as it is presumed to be associated with increasing number of IAS cases.","PeriodicalId":324006,"journal":{"name":"Chronicle of Diabetes Research and Practice","volume":"80 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116952668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Case Studies","authors":"","doi":"10.4337/9781839100246.00024","DOIUrl":"https://doi.org/10.4337/9781839100246.00024","url":null,"abstract":"In Nigeria, an activist started a long-term program focusing on sexism and critical thinking skills. Boys meet for weekly discussions about such topics as gender-based oppression, sexual rights, violence, power within the family, intimate relationships, sexual health, human rights, and democracy. To help the boys develop as critical thinkers, the teachers rely heavily on Socratic dialogue and teach logic and verbal skills. Rather than target the out-of-school young people at highest risk, the program recruits participants who are in school and who are particularly bright social leaders.","PeriodicalId":324006,"journal":{"name":"Chronicle of Diabetes Research and Practice","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121930295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Davy Bailey, Paula Kelly, Tom Iocono, Joe Sullivan, Pat Jackson, Wendy Swanson, Hollie Jicha, Greg Wilson, Melinda Springer, J. Stevens, Julia Valentino
{"title":"Basic Sciences","authors":"Davy Bailey, Paula Kelly, Tom Iocono, Joe Sullivan, Pat Jackson, Wendy Swanson, Hollie Jicha, Greg Wilson, Melinda Springer, J. Stevens, Julia Valentino","doi":"10.1063/1.3050545","DOIUrl":"https://doi.org/10.1063/1.3050545","url":null,"abstract":"Faculty Council chair status: Prior to the meeting, by electronic ballot, Kelly was elected Faculty Council Chair Pro Tem. Kelly will work with past Chair Springer and Michael Kilgore, who has indicated interest in serving as the next chair, pro tem, to maintain continuity in ongoing faculty council activities. A proposal to permit rotating chairs in the faculty council, as well as other options for chair service, will be presented to the COM faculty for consideration and subsequent vote at the December general faculty meeting.","PeriodicalId":324006,"journal":{"name":"Chronicle of Diabetes Research and Practice","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132329830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}