E. Bekoe, Cindy Kitcher, Nana Ama Mireku Gyima, Gladys Schwinger, M. Frempong
{"title":"Medicinal Plants Used as Galactagogues","authors":"E. Bekoe, Cindy Kitcher, Nana Ama Mireku Gyima, Gladys Schwinger, M. Frempong","doi":"10.5772/INTECHOPEN.82199","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.82199","url":null,"abstract":"The recommended diet for human infants within the first 6 months of life is breast milk. No other natural or artificial formulation has been able to match up to this gold standard. Mothers who have attempted to pursue exclusive breastfeeding can, however, attest to numerous nutritional and non-nutritional challenges mainly resulting in insufficient milk production (hypogalactia) or the absence of milk production (aga-lactia). There are very few and officially recommended orthodox drugs to increase lactation. The most widely used galactagogues being chlorpromazine, sulpiride, metoclopramide and domperidone are associated with very high incidences of unpleasant side effects including their extra-pyramidal effects in both mother and infant. There is therefore a need to keep searching for more acceptable galactagogues. This section reviews current literature on medicinal plants used within the local Ghanaian com-munity to enhance lactation. Various electronic databases such as PubMed, Science Direct, SciFinder and Google Scholar as well as published books on Ghanaian medicinal plants were searched. A total of 22 plants belonging to 13 families were reviewed with regards to their medicinal values, information on lactation and toxicity.","PeriodicalId":322656,"journal":{"name":"Pharmacognosy - Medicinal Plants","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116313002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Carlos Alberto Méndez-Cuesta, Ana Laura Esquivel Campos, David Salinas Sánchez, Cuauhtémoc Pérez González, Salud Pérez Gutiérrez
{"title":"Cytotoxic and Antitumoral Activities of Compounds Isolated from Cucurbitaceae Plants","authors":"Carlos Alberto Méndez-Cuesta, Ana Laura Esquivel Campos, David Salinas Sánchez, Cuauhtémoc Pérez González, Salud Pérez Gutiérrez","doi":"10.5772/INTECHOPEN.82213","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.82213","url":null,"abstract":"The WHO says that annual cases of cancer will increase from 14 million in 2012 to 22 million in the next two decades. Cancer is the second cause of death in the world; in 2015, it caused 8.8 million deaths. On the other hand, it is necessary to consider that 70% of the total deaths due to this disease occur in developing coun-tries, who have the least resources to acquire the drugs of choice for the treatment of this disease. Although there are treatments and these are effective, there are currently cases of resistance to drugs used to treat this disease, which has led to the search for new sources of drugs or compounds effective against the cancer being active; plants are the possible sources to achieve this. Cucurbitaceae is a family of plants widely distributed on the planet which has been used traditionally for the treatment of this disease and from they have been isolated different cucurbitanes. These compounds possess a wide biological activity, antidiabetic, anti-inflamma-tory, hepatoprotective, or cytotoxic and antitumoral effects. The aim of this review is to present 51 cucurbitacin compounds and 2 with different structures isolated from Cucurbitaceae plants with cytotoxic or antitumoral activity.","PeriodicalId":322656,"journal":{"name":"Pharmacognosy - Medicinal Plants","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116695808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Anticancer Activity of Uncommon Medicinal Plants from the Republic of Suriname: Traditional Claims, Preclinical Findings, and Potential Clinical Applicability against Cancer","authors":"D. Mans, E. Irving","doi":"10.5772/INTECHOPEN.82280","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.82280","url":null,"abstract":"Despite much progress in our understanding of the essence of cancer, remarkable advances in methods for early diagnosis, the expanding array of antineoplastic drugs and treatment modalities, as well as important refinements in their use, this disease is among the leading causes of morbidity and mortality in many parts of the world. In fact, the next decade is anticipated to bring over 20 million new cases per year globally, about half of whom will die from their disease. This indicates a need for better strategies to deal with cancer. One way to go forward is to draw lessons from ancient ethnopharmacological wisdom and to evaluate the plant biodiversity for compounds with potential antineoplastic activity. This approach has already yielded many breakthrough cytotoxic drugs such as vincristine, etoposide, paclitaxel, and irinotecan. The Republic of Suriname (South America), renowned for its pristine and highly biodiverse rain forests as well as its ethnic, cultural, and ethnopharmacological diversity, could also contribute to these developments. This chapter addresses the cancer problem throughout the world and in Suriname, extensively deals with nine plants used for treating cancer in the country, and concludes with their pros-pects in anticancer drug discovery and development programs.","PeriodicalId":322656,"journal":{"name":"Pharmacognosy - Medicinal Plants","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124427552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Wróblewska, D. Oliveira, M. T. Grombone-Guaratini, P. Moreno
{"title":"Medicinal Properties of Bamboos","authors":"K. Wróblewska, D. Oliveira, M. T. Grombone-Guaratini, P. Moreno","doi":"10.5772/INTECHOPEN.82005","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.82005","url":null,"abstract":"Bamboos are described as one of the most important renewable, easily obtained, and valuable of all forest resources. These plants belong to the grasses’ family ( Poaceae ), which covers about a quarter of the world’s plant population, within the subfamily Bambusoideae. The estimated diversity of bamboos in the world is approximately 1400 species, distributed in 116 genera. Bamboo species have been used in Southeast Asia, as a base material to produce paper, furniture, boats, bicycles, textiles, musical instruments, and food, and their leaves have also been used as a wrapping material to prevent food deterioration since ancient times. These species accumulate biologically active components such as polyphenols and other secondary plant metabolites that might explain the use of bamboo leaves in Asian traditional medicine for the treatment of hypertension, arteriosclerosis, cardiovascular disease, and certain forms of cancer. Besides the usual secondary metabolites, bamboo extracts may contain biologically active peptides and polysaccharides that still need to be further studied for their activity and their synergistic with other metabolites. Most of the studies found in the literature are from Asian bamboo species, and the potential of the Southern American species is yet to be explored.","PeriodicalId":322656,"journal":{"name":"Pharmacognosy - Medicinal Plants","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122792485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}