Kazanskij Medicinskij Zurnal最新文献

{"title":"The role of dehydration in the development of acute kidney injury in patients with COVID-19","authors":"Elvira R. Sakaeva, Aleksander М. Shutov, Elena V. Efremova, Mariya М. Rebrovskaya, Ekaterina S. Semenova","doi":"10.17816/kmj551845","DOIUrl":"https://doi.org/10.17816/kmj551845","url":null,"abstract":"Background. Acute kidney injury often complicates the course of COVID-19; in many patients it develops even before hospitalization, and the reasons for its development are not sufficiently clear.
 Aim. To study the role of dehydration in the development of community-onset acute kidney injury in COVID-19.
 Material and methods. 329 patients with COVID-19 were examined (age 58.014.3 years, 172 men, 157 women). Acute kidney injury was diagnosed according to the Russian recommendations of 2020. To determine prerenal acute kidney injury, the ratio of blood urea nitrogen to blood creatinine was calculated, and to diagnose dehydration the calculated osmolarity of blood serum. Data are presented for a normal distribution as the arithmetic mean and standard deviation (MSD), for a non-normal distribution as a median (Me) and interquartile range (IQR). Univariate and multivariate logistic regression analyzes were used. To assess the diagnostic significance of quantitative characteristics in predicting a certain outcome, the ROC curve analysis method was used. Differences were considered statistically significant at p 0.05.
 Results. Acute kidney injury was diagnosed in 70 (21.3%) patients, of which 58 (82.9%) were community-acquired. In 16 (27.6%) patients with community-onset acute kidney injury, it was of a prerenal nature, of which in 13 (81.3%) the calculated serum osmolarity exceeded 295 mOsm/L. Independent factors directly associated with prerenal prehospital acute kidney injury were estimated serum osmolarity (p 0.001), C-reactive protein level (p 0.001) and age (p=0.003) (R2=0.23, F=33,34).
 Conclusion. Acute kidney injury complicates the course of COVID-19, and in most patients, it develops even at the prehospital stage. Estimated serum osmolarity is directly and independently associated with prerenal community-onset acute kidney injury, suggesting the important role of dehydration in its development.","PeriodicalId":32248,"journal":{"name":"Kazanskij Medicinskij Zurnal","volume":"97 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135426906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The state policy of the Russian Empire in the fight against the syphilis epidemic among foreign communities in the northeastern districts of Eastern Siberia in the 19th century","authors":"Gaidar M. Gaidarov, Tatyana I. Alekseevskaya, Tatyana V. Demidova, Oleg Yu. Sofronov","doi":"10.17816/kmj462806","DOIUrl":"https://doi.org/10.17816/kmj462806","url":null,"abstract":"The article considers the chronology of historical events, highlighting the formation of the state policy of the Russian Empire in the fight against the spread of syphilis among foreign communities in the northeastern districts of Eastern Siberia. Archival materials are systematized, according to which the personnel, material and technical, financial support of organizational, treatment and preventive measures to combat the syphilis epidemic is assessed. The study of the materials allows to draw a reasoned conclusion that the government of the Russian Empire pursued a systematic, persistent policy of fighting to eradicate syphilis among foreign communities. In order to study and evaluate the state policy of the Russian Empire to eradicate syphilis among the foreign communities of the northeastern districts of Eastern Siberia in the 19th century, we used the historical method, which is based on the study of archival materials from the State Archives of the Irkutsk Region, indicating the organization of the fight against the epidemic syphilis among foreign communities of the northeastern districts of Eastern Siberia in the 19th century. Concern for the preservation of the population in the north-eastern districts of Eastern Siberia, newly annexed to the Russian Empire, according to the archival materials of the State Archive of the Irkutsk Region, has become an urgent task for both the government as a whole and the Governor-General of Eastern Siberia, the heads of the Yakutsk Region, Primorsky Region and Kamchatka. The state policy of the Russian Empire in the fight against the syphilis epidemic was focused on resolving issues of staffing the northern districts with medical ranks, providing them with social benefits in order to retain them for work in Eastern Siberia, identifying sources of funding and organizing the construction of syphilitic hospitals, resolving issues of ensuring the supply of medicines, pharmacy supplies, hospital supplies, clothing, food for sick people.","PeriodicalId":32248,"journal":{"name":"Kazanskij Medicinskij Zurnal","volume":"71 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135425306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Topical repellents for malaria prevention","authors":"- -","doi":"10.17816/kmj595745","DOIUrl":"https://doi.org/10.17816/kmj595745","url":null,"abstract":"This publication is the Russian translation of the Plain Language Summary (PLS) of the Cochrane Systematic Review: Gabaldn Figueira JC, Wagah MG, Adipo LB, Wanjiku C, Maia MF. Topical repellents for malaria prevention. Cochrane Database of Systematic Reviews. 2023. Issue 8. Art. No.: CD015422. DOI: 10.1002/14651858.CD015422.pub2.","PeriodicalId":32248,"journal":{"name":"Kazanskij Medicinskij Zurnal","volume":"57 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135425486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of interval hypoxic therapy in the hypoxia-hyperoxia mode on the hemostatic system of patients who have suffered a new coronavirus infection COVID-19","authors":"Indira A. Misirova, Omari-Butta A. Tsuntaev, Madina V. Merzhoeva, Makka V. Merzhoeva, Irina Kh. Borukaeva","doi":"10.17816/kmj472087","DOIUrl":"https://doi.org/10.17816/kmj472087","url":null,"abstract":"Background. The positive effect of interval hypoxic therapy in the treatment of many diseases has become the basis for its use in rehabilitation after a new coronavirus infection to normalize disorders of the hemostatic system.
 Aim. To identify the peculiarities of the interval hypoxic therapy effect on the hemostatic system of patients who have suffered a new coronavirus infection.
 Material and methods. The work was carried out from April 2020 to May 2022. 220 men aged 4559 years (average age 48.82.4 years) were examined. The main group included 90 people who had a moderate coronavirus infection a month ago; the control group (n=70) was represented by relatively healthy people; the comparison group (n=60) suffered coronavirus infection and underwent standard rehabilitation without hypoxic therapy. The content of platelets, D-dimer, international normalized ratio, prothrombin time, activated partial thromboplastin time, antithrombin III activity, interleukin-6 level, and C-reactive protein content in the blood serum was determined. To assess statistically significant differences, a parametric method applying paired and unpaired Student's t-test was used. Differences were considered statistically significant at p 0.05.
 Results. In patients of the main group, a violation of the hemostatic system, indicating increased thrombogenicity of the blood against the background of persistent inflammatory activity, was revealed. After interval hypoxic therapy, the platelet count increased to 215.5323.57109/l (p=0.035), activated partial thromboplastin time to 26.741.84 s (p=0.035), international normalized ratio to 0.890.06 (p=0.005), antithrombin III activity in the blood up to 81.814.33% (p=0.007); the level of fibrinogen decreased to 3.861.09 g/l (p=0.035) and the content of D-dimer in the blood to 255.5817.36 ng/ml (p=0.035). There was a decrease in the level of interleukin-6 to 6.030.65 pg/ml (p=0.035) and C-reactive blood protein to 1.030.15 mg/l (p=0.035).
 Conclusion. Interval hypoxic therapy had a normalizing effect on the hemostatic system of patients who suffered a new coronavirus infection, as a result of suppressing the inflammatory process in the body.","PeriodicalId":32248,"journal":{"name":"Kazanskij Medicinskij Zurnal","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135425487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"On predicting outcomes in patients with chronic heart failure with frailty syndrome","authors":"Ivan V. Podobed, Nuruldin M.Kh. Al majmai, Lyudmila V. Titareva, Marina V. Silytina, Alexey S. Ponomarev","doi":"10.17816/kmj569203","DOIUrl":"https://doi.org/10.17816/kmj569203","url":null,"abstract":"Background. The presence of frailty negatively affects the prognosis of patients with chronic heart failure, increasing the frequency of hospitalizations, limiting treatment options, and also increasing the mortality of patients.
 Aim. To develop a model for predicting mortality in patients with decompensated chronic heart failure, including frailty syndrome.
 Material and methods. 107 patients aged 4595 years with decompensated chronic heart failure were studied. Four age groups were formed: the first 29 patients aged 4559 years old (average age 53.94.5 years), the second 31 elderly patients (6074 years old, average 68.35.0 years), the third 40 senile people (7590 years, average age 81.54.1 years), the fourth 7 long-lived patients (90 years, average 921.4 years). A comprehensive geriatric assessment was performed using the program Optimization of care in geriatrics depending on the degree of frailty. A multivariate logistic regression analysis was performed to select mortality predictors.
 Results. The prognostic model included 6 independent variables: age 1.05 [0.96; 1.17] (p=0.28), male gender 0.25 [0.03; 1.65] (p=0.17), frailty of severe or terminal degree 5.56 [1.08; 37.14] (p=0.05), IV functional class according to the classification of New York Heart Association 3.41 [0.60; 27.35] (p=0.19), ejection fraction 50% or more 0.29 [0.03; 2.28] (p=0.26), ejection fraction 4049% 0.40 [0.05; 2.60] (p=0.36). The sensitivity of the model was 62%, specificity 82%, prognostic effectiveness 88%.
 Conclusion. Severe or terminal asthenia is the strongest predictor of mortality, increasing the risk of an unfavorable outcome by 5.56 times.","PeriodicalId":32248,"journal":{"name":"Kazanskij Medicinskij Zurnal","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135425305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"His calling is to heal people (on the 70th anniversary of Professor I.S. Malkov)","authors":"- -","doi":"10.17816/kmj595890","DOIUrl":"https://doi.org/10.17816/kmj595890","url":null,"abstract":"","PeriodicalId":32248,"journal":{"name":"Kazanskij Medicinskij Zurnal","volume":"46 22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135425484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Experience in the treatment of lymphatic malformations in children","authors":"Maria A. Zykova, Ildar N. Nurmeev, Leonid M. Mirolubov, Guzel R. Valeeva, Valery I. Morozov","doi":"10.17816/kmj100427","DOIUrl":"https://doi.org/10.17816/kmj100427","url":null,"abstract":"Background. In the treatment of lymphatic malformations, the problem of radical removal and a high risk of recurrence remains.
 Aim. Improving the efficiency of treatment of children with lymphatic malformations by introducing new surgical methods and optimizing sclerotherapy.
 Material and methods. The results of treatment of 150 patients with lymphangiomas and an experimental study of the effects of sclerosing drugs on the lining of lymphangioma are presented. The study included 67 (44.7%) girls and 83 (55.3%) boys. The patients were divided into three groups. The first group (72 children) consisted of patients with radical removal of lymphangioma. The second group included 70 patients with partial resection of lymphangioma and sclerosis of residual cavities. The third group (8 children) consisted of patients operated on by video endoscopic method. A histological study of micropreparations of lymphangioma after sclerosis with ethanol and sodium tetradecyl sulfate with an exposure of 5 minutes was carried out. Statistical analysis was carried out using the StatTech v. 2.2.0 using methods of parametric and non-parametric analysis. Results were considered statistically significant at p 0.05.
 Results. In the first group of patients, 9 (11.1%) relapses occurred, in the second 12 (12.3%), in the third group 0 relapses. Treatment combined with sclerotherapy did not lead to a significant increase in the recurrence rate (p=0.541). Types of lymphatic malformations and their location did not significantly affect the risk of recurrence (p=0.232 and p=0.552, respectively). Sclerosis of the lymphangioma lining with 70% ethanol and a liquid form of sodium tetradecyl sulfate caused total desquamation of the endothelium. Sclerosing with the foam form of sodium tetradecyl sulfate led to total desquamation of the endothelium during a 3-minute exposure.
 Conclusion. The introduction of minimally invasive methods of treatment and the improvement of sclerosis will make the results of treatment of children with lymphangiomas better.","PeriodicalId":32248,"journal":{"name":"Kazanskij Medicinskij Zurnal","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136361338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[The problem of active control during labor].","authors":"L A Kozlov, Banshchik Fya, K B Voronin, N L Banshchik","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":32248,"journal":{"name":"Kazanskij Medicinskij Zurnal","volume":"56 5","pages":"41-3"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22003172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Short-term and long-term results of the massive use of intrauterine contraception].","authors":"Z N Yakubova, Amirov Rkh, N A Shamova, R S Baryshkina, F A Miftakhova, I F Polyakov, F A Siraeva","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":32248,"journal":{"name":"Kazanskij Medicinskij Zurnal","volume":"56 5","pages":"36-9"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22003171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Sensitivity to antibiotics of the microflora isolated from endometritis after infected abortion].","authors":"V P Sobolev, G S Minasova, I V Vlasova","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":32248,"journal":{"name":"Kazanskij Medicinskij Zurnal","volume":"4 ","pages":"65-6"},"PeriodicalIF":0.0,"publicationDate":"1970-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22003169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}