M. Srivastava, Sunil K. S. Bhadouriya, R. Saxena, A. Singh, Abhinav K. Srivastava, M. Bisht
{"title":"Comparative clinical evaluation of effect of topical verses systemic anti -allergic drug in allergic rhinitis: a prospective study","authors":"M. Srivastava, Sunil K. S. Bhadouriya, R. Saxena, A. Singh, Abhinav K. Srivastava, M. Bisht","doi":"10.18203/ISSN.2454-5929.IJOHNS20175615","DOIUrl":"https://doi.org/10.18203/ISSN.2454-5929.IJOHNS20175615","url":null,"abstract":"Nasal passages form one of the chief sources of contact of the human with his environ-ment. Hence, it is natural that the mucosa of the area is the victim of assault with multi-tudes of potential allergens. Allergic rhinitis is an inflammatory disease with worldwide prevalence of 10-40%. Clinically allergic rhini-tis manifests as itching, sneezing, rhinorrhea, congestion and itchy eyes. Allergic rhinitis is a disease with low mortality but significantly lowers the quality of life and functioning. Both oral and intranasal antihistamines are approved for the first-line treatment of aller-gic rhinitis and both formulations result in a reduction in symptoms and an improvement in quality of life. The following study was de-signed to assess the efficacy and safety of the azelastine nasal spray in comparison to levocetrizine in patients with allergic rhinitis. Out of the 68 patients, 34 cases were treated with topical azelastine (group A), while remain-ing 34 with systemic levocetrizine (group B). The effects of anti-allergic drugs have been studied on the basis of relief of symptoms and change in histopathology. Comparing the post therapy clinical and histopathological results in this study, azelastine nasal spray was found to be more effective and safe in the treatment of al-lergic rhinitis than levocetrizine.","PeriodicalId":322167,"journal":{"name":"Otolaryngology online journal","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116365228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"BACTERIOLOGICAL PROFILE OF CHRONIC SUPPURATIVE OTITIS MEDIA AND ITS CLINICAL SIGNIFICANCE IN RURAL AREA","authors":"M. Srivatsava, S. Tyagi","doi":"10.14260/JEMDS/2015/2221","DOIUrl":"https://doi.org/10.14260/JEMDS/2015/2221","url":null,"abstract":"Background: Middle ear infection is one of the most common condition in ENT practice, particularly in our country. Its significance lies in its chronicity and its dreaded complications like hearing loss and cholesteatoma. Chronic suppurative Otitis media and its complications are among the most common conditions seen by both the otologist and pediatrician. Both gram positive and negative organisms are responsible for infection of the middle ear. Aims: The study was primarily carried out in 200 cases of C.S.O.M. to determine the bacteriological flora and to study the antibiotic sensitivity pattern of the organisms isolated on culture from discharging ears. Results: In our study Pseudomonas aeruginosa was found to be the most common isolated bacteria (40.65% [100/246]), followed by Staphylococcus aureus (14.63% [36/246]), Klebsiella aerogenes (11.78% [29/246]) and Proteus Mirabilis (10.56% [26/246]). Among the anerobic organisms Peptostreptococcus (5.69%) was the most common followed by Propionibacterium (4.06%) and Bacteroids spp. (3.65%). Amikacin was the most effective antibiotic in the present study. It was effective against maximum number of strains 97 (95.48%) followed by Gentamycin 95 (92.36%) and Ciprofloxacin 93 (91.30%). Cefoperazone 88 (86.42%), Cefotaxime 78 (74.54%) and Ofloxacin 64 (62.68%). Conclusion: Efficient and effective treatment of CSOM is based on the knowledge of causative micro-organisms and thus their antimicrobial sensitivity ensures proper clinical recovery and avoidance of the possible dreaded complications. It has been observed that human negligence is one of the main factor responsible for the development of antibiotic resistance. Along with the indiscriminate use of antibiotics by the treating physician the lack of compliance on part of the patient also results in emergence of resistance and thus in treatment failure. It has been frequently encountered that as soon as the symptoms subside and improvement in condition occurs, many patients stop taking antibiotics before completion of therapy and allow partially resistant microbes to flourish and become completely resistant or even multi drug resistant.","PeriodicalId":322167,"journal":{"name":"Otolaryngology online journal","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128655436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"KIMURA’S DISEASE: A RARE CAUSE OF NECK SWELLING","authors":"S. Prasad, V. Gupta, Ashok Kumar, Sulabha M. Naik","doi":"10.17511/ijpr.2014.i02.05","DOIUrl":"https://doi.org/10.17511/ijpr.2014.i02.05","url":null,"abstract":"KIMURA'S DISEASE is a rare condition and manifests as solitary or multiple subcutane-ous nodules in the head and neck region, with eosinophilia and adenopathy. It is a be-nign chronic inflammatory disorder of un-known etiology. Histologically the lesions are characterized by hyperplastic lymphoid tis-sue, an inflammatory infiltrate rich in eosino-phils and a proliferation of postcapillary ven-ules. Hypereosinophilia in the blood and ele-vated levels of circulating IgE are found. The disease progresses slowly and is endemic to Asians. Treatment consists of surgical resec-tion and administration of parenteral steroids in relapse cases. The prognosis is good and no malignant transformation has been ever ob-served.","PeriodicalId":322167,"journal":{"name":"Otolaryngology online journal","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127660699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"MUTATIONAL FALSETTO: A PANORAMIC CONSIDERATION","authors":"Srikamakshi Kothandaraman, B. Thiagarajan","doi":"10.6084/M9.FIGSHARE.923502.V1","DOIUrl":"https://doi.org/10.6084/M9.FIGSHARE.923502.V1","url":null,"abstract":"This article is intended to present everything that is known about puberphonia in a comprehensive yet concise manner. The evolution of the approach and attitude to its treatment from ancient concepts to recent trends is highlighted.","PeriodicalId":322167,"journal":{"name":"Otolaryngology online journal","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114497509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Online Publishing current scenario","authors":"B. Thiagarajan, G. Ramamoorthy","doi":"10.5072/ZENODO.75195","DOIUrl":"https://doi.org/10.5072/ZENODO.75195","url":null,"abstract":"This article attempts to unravel the current scenario in online publishing. Advent of internet has brought with it tremendous changes in the publishing industry. What was hither to an industry dominated by publisher has been thrown open to one and sundry. Online publishing has brought with it a reach which was hitherto never been imagined. In the normal course it would take atleast a year to publish a manuscript. Online publishing has managed to bring this time down to a few weeks / at most a month. This article attempts to discusses the positives and perils of online publishing scenario.","PeriodicalId":322167,"journal":{"name":"Otolaryngology online journal","volume":"56 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116606922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Srikamakshi Koth, A. Thiagarajan, Seethalakshmi Narashiman
{"title":"THE RETURN OF THE STRANGLER? CASE REPORT OF A FATAL CASE OF DIPHTHERIA","authors":"Srikamakshi Koth, A. Thiagarajan, Seethalakshmi Narashiman","doi":"10.5072/ZENODO.75225","DOIUrl":"https://doi.org/10.5072/ZENODO.75225","url":null,"abstract":"This article is a case report of a case of diphtheria which presented as diphtheritic tonsillitis in stridor and finally succumbed to diphtheritic myocarditis. Here we describe the case presentation, the treatment modalities undertaken, and the fatal course of events followed by an elaborate discussion on diphtheria","PeriodicalId":322167,"journal":{"name":"Otolaryngology online journal","volume":"2013 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121590433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"ROLE OF ANATOMICAL OBSTRUCTION IN THE PATHOGENESIS OF CHRONIC SINUSITIS","authors":"B. Thiagarajan, Y. Basith","doi":"10.5455/JORL.51-1330263458","DOIUrl":"https://doi.org/10.5455/JORL.51-1330263458","url":null,"abstract":"Sinusitis is a commonly diagnosed condition in the general population. This article is a study to asses the role of anatomical obstruction in the pathogenesis of chronic sinusitis, based on symptomatology and radiological findings of the patients. The frequency of major anatomical variants like deviated nasal septum, concha bullosa, and paradoxical middle turbinate leading to chronic sinusitis has been analyzed. In majority of cases the obstruction at osteomeatal complex is found to be caused by more than one factor.","PeriodicalId":322167,"journal":{"name":"Otolaryngology online journal","volume":"47 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132267522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Endoscope assisted myringoplasty","authors":"B. Thiagarajan, V. Ulaganathan","doi":"10.5455/51-1327835507.JORL","DOIUrl":"https://doi.org/10.5455/51-1327835507.JORL","url":null,"abstract":"Myringoplasty is commonly done under microscopy. This article discusses the experience of the authors in performing myringoplasty using endoscope. Endoscope is being widely used to perform various surgeries. Endoscopes are very useful while operating in cavities. In this study authors report their results of 50 myringoplasties performed using endoscope. This article reveals that results of myringoplasty performed using endoscope are more or less similar to that of myringoplasty performed using microscope","PeriodicalId":322167,"journal":{"name":"Otolaryngology online journal","volume":"61 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124867561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Karthikeyan Arjunan, B. Thiagarajan, Seethalakshmi Narashiman
{"title":"ROLE OF TISSUE ADHESIVE IN OTORHINOLARYNGOLOGY","authors":"Karthikeyan Arjunan, B. Thiagarajan, Seethalakshmi Narashiman","doi":"10.5455/JORL.51-1335890250","DOIUrl":"https://doi.org/10.5455/JORL.51-1335890250","url":null,"abstract":"This paper summarises the effectiveness of tissue adhesives in otorhinolaryngology. Although the adhesion system cannot and should not replace surgical suture, it provides valuable assistance in tissue synthesis and in local haemostasis, particularly in cases where conventional suture methods are especially difficult to apply. In addition to good adhesion, an elastic consistency, and good tissue compatibility, the adhesive is completely absorbed. The system has been used successfully in myringoplasty, laryngectomy during pharyngeal closure, repair of CSF leak, laryngocele, and ossiculoplasty.","PeriodicalId":322167,"journal":{"name":"Otolaryngology online journal","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117148693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Gore tex medialization thyroplasty- A case series","authors":"K. Thiagarajan","doi":"10.5072/ZENODO.74285","DOIUrl":"https://doi.org/10.5072/ZENODO.74285","url":null,"abstract":"Unilateral vocal fold paralysis classically presents with voice change, aspiration of ingested materials and cough. Medialization thyroplasty has become treatment of choice for un recovering vocal fold palsy. Still the ideal implant has not been defined in the surgical medialization of vocal folds. We present our experience of gore tex as the implant material.","PeriodicalId":322167,"journal":{"name":"Otolaryngology online journal","volume":"56 2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128954468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}