Journal of Orthopaedics and Allied Sciences最新文献_第9页

Current view of bone regeneration using mesenchymal stem cells 间充质干细胞骨再生的现状

Journal of Orthopaedics and Allied Sciences Pub Date : 2016-01-01 DOI: 10.4103/2319-2585.180677

O. Al-Mohrej, Noura K Al-Ayedh, Abdullah Y Al-Awlah, Nader S. Al-Kenani

{"title":"Current view of bone regeneration using mesenchymal stem cells","authors":"O. Al-Mohrej, Noura K Al-Ayedh, Abdullah Y Al-Awlah, Nader S. Al-Kenani","doi":"10.4103/2319-2585.180677","DOIUrl":"https://doi.org/10.4103/2319-2585.180677","url":null,"abstract":"Bone regeneration, reparative and restorative techniques of bone length discrepancies, correction of posttraumatic and congenital defects and deformities can be induced mesenchymal stem cells (MSCs) which is taken from the bone marrow. In this review article, we aimed to have a look at MSCs for bone and tissue regeneration. MEDLINE ® , Embase™, the Science Citation Index, and Google™ Scholar were used to look for relevant articles which published in English since January 2000. Studies on bone regeneration using MSCs in the field of clinical orthopedics were retrieved. The bone graft can create a self-reliant mechanism to induce bone cellular environment that adapts to the whole skeletal nature. There are several factors contributory to deciding which approach to take. These include the type of bone deformities, defects, the biological setting of the patient, the nature of the reparative process desired, and surgical or orthopedic possibility of conducting all these processes. All these factors and several others should be taken into consideration and careful medical consultation. Orthopedics along with osteology made much headway in restoring bone and tissue in uniquely medical approach that is MSCs through the autologous cancellous bone taken from the bone marrow.","PeriodicalId":31882,"journal":{"name":"Journal of Orthopaedics and Allied Sciences","volume":"4 1","pages":"1 - 4"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70435495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Complete avulsion of the adductor longus in a semi-professional football player: Rapid return to play with nonoperative treatment 半职业足球运动员长内收肌完全撕脱:非手术治疗下快速恢复比赛

Journal of Orthopaedics and Allied Sciences Pub Date : 2016-01-01 DOI: 10.4103/2319-2585.180693

Vince W. Lands, D. Avery, Steven Puccio

{"title":"Complete avulsion of the adductor longus in a semi-professional football player: Rapid return to play with nonoperative treatment","authors":"Vince W. Lands, D. Avery, Steven Puccio","doi":"10.4103/2319-2585.180693","DOIUrl":"https://doi.org/10.4103/2319-2585.180693","url":null,"abstract":"The adductor longus has become recognized as one of the more commonly injured muscles in the medial compartment. Acute complete rupture injuries occurring at the proximal aspect of the muscle are less common. Limited data exist regarding management of the injuries in athletes required for return to play and functioning. The current data favors operative management; however, nonoperative treatment may be a viable option. Nonoperative management of avulsion injuries of the proximal adductor longus tendon may prove equal results to surgical repair in return to play and functioning. A semi-professional football player sustained a left groin injury while participating in the play. Due to continued pain, swelling, and suspicion of injury, a magnetic resonance imaging was performed diagnosing a complete tear of proximal adductor longus tendon. Physical examination, strength, and range of motion were recorded until the patient was able to function normally without strength deficit, the range of motion loss, and the return of speed. The player was treated nonoperatively and was eventually allowed to return to play. The time of return to play was 6 weeks. Strength deficit was not appreciated or loss of motion and player was able to return to baseline function. Nonoperative management of complete avulsion injuries of the proximal adductor longus tendon result in faster return to play than operative management even if significant retraction is present.","PeriodicalId":31882,"journal":{"name":"Journal of Orthopaedics and Allied Sciences","volume":"4 1","pages":"45 - 48"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70435581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Carpal tunnel syndrome: Ultrasonographic evaluation of median nerve diameter 腕管综合征:正中神经直径的超声评价

Journal of Orthopaedics and Allied Sciences Pub Date : 2016-01-01 DOI: 10.4103/2319-2585.180690

J. Kamath, Babul Reddy, Umapathy Sivam, A. Venugopal, N. Jayasheelan

{"title":"Carpal tunnel syndrome: Ultrasonographic evaluation of median nerve diameter","authors":"J. Kamath, Babul Reddy, Umapathy Sivam, A. Venugopal, N. Jayasheelan","doi":"10.4103/2319-2585.180690","DOIUrl":"https://doi.org/10.4103/2319-2585.180690","url":null,"abstract":"Background: Carpal tunnel syndrome is the most frequently encountered peripheral compression neuropathy. Diagnosis of carpal tunnel syndrome involves physical examination, nerve conduction studies and electromyography. Ultrasonography (USG) examination of median nerve in carpal tunnel has been proposed as a useful alternative in diagnosing carpal tunnel syndrome. Materials and Methods: Patients were selected from those undergoing diagnostic workup for carpal tunnel syndrome in pre-treatment period. USG was performed using 11 MHz linear array transducer. Cross-sectional area at each level, major and minor axes were measured. Results: In our study, the mean median nerve cross sectional area at proximal part of carpal tunnel by direct method was 12.33 mm 2 in patients and 7.33 mm 2 in controls. By indirect method it was 12.01 mm 2 and 6.633 mm 2 in cases and controls respectively. In this study we found significant difference in flattening ratio between cases and controls. The mean flattening ratio in distal part of tunnel (at the level of hook of hamate) was 2.97 and 2.38 in cases and controls respectively. The sensitivity and specificity for cut-off value ≥2.5 was 76% and 63% respectively. Conclusion: We found that best discriminatory criterion for diagnosis of carpal tunnel syndrome are median nerve cross sectional area in the proximal part of carpal tunnel ≥9 mm 2 (Direct method) and ≥8.5 mm 2 (Indirect method). With our experience, we found it easier to evaluate the median nerve in the carpal tunnel in the disto proximal sequence by identifying the flexor pollicislongus (FPL) first with dynamic evaluation. As the percentage of space occupying lesions causing symptoms in unilateral (atypical) carpal tunnel syndrome is 35%, we highly recommend this pre-operative investigation in all carpal tunnel syndrome patients.","PeriodicalId":31882,"journal":{"name":"Journal of Orthopaedics and Allied Sciences","volume":"4 1","pages":"14 - 17"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70435796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Percutaneous autologous stem cell enriched marrow concentrate injection for treatment of cases of impaired fracture healing with implant in situ: A cost-effective approach in present Indian scenario 经皮自体干细胞富集骨髓浓缩液注射治疗原位植入骨折愈合受损病例:目前印度的一种经济有效的方法

Journal of Orthopaedics and Allied Sciences Pub Date : 2016-01-01 DOI: 10.4103/2319-2585.172721

Sachin Upadhyay, H. Varma, V. Yadav

{"title":"Percutaneous autologous stem cell enriched marrow concentrate injection for treatment of cases of impaired fracture healing with implant in situ: A cost-effective approach in present Indian scenario","authors":"Sachin Upadhyay, H. Varma, V. Yadav","doi":"10.4103/2319-2585.172721","DOIUrl":"https://doi.org/10.4103/2319-2585.172721","url":null,"abstract":"Background: The objective of present study is to investigate the feasibility of proposed methodology in present Indian scenario, to enhance fracture repair in cases of impaired healing with the implant in situ using autologous bone marrow concentrate. During critical analysis, the existing study also aimed to assess the outcome (both objective and subjective) as well as to document complications specific to the proposed therapy if any. Materials and Methods: First the marrow is aspirated from posterior iliac crests. After that Ficoll-Paque technique of density gradient separation for the isolation of mononuclear cell populations enriched with stem cells is employed. Later, the concentrate is injected into critical-sized defects of eight patients with stable fracture delayed/nonunion via fluoroscopic guidance. New bone formation was evaluated by X-rays in two standard planes (anteroposterior (AP)/lateral). Level of statistical significance was set at a P < 0.05. Result: The critical osseous defect reached radiographic observable union by a mean of 12.28 ± 1.38 weeks. A distance of 5 mm or less between the fractures′ ends resulted in healing in seven cases (87.5%). The results of the Likert four-point scale showed that majority were very satisfied with the outcome of the procedure (Cronbach′s alpha coefficient (follow-up): 0.93 (6 week); 1.0 (1 year)). There were no adverse events reported during the procedure. Conclusion: Our preliminary results indicate that the approach proposed is feasible and effective in the management of stable (implant in situ) fracture with impaired healing. In context of its cost-effectiveness, we recommend to follow proposed methodology in present Indian scenario.","PeriodicalId":31882,"journal":{"name":"Journal of Orthopaedics and Allied Sciences","volume":"4 1","pages":"18 - 29"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70434951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Simultaneous bilateral Mason type IIb radial head fractures in a young female: Was an increased carrying angle the cause? 年轻女性双侧Mason型IIb型桡骨头同时骨折:是搬运角度增加的原因吗?

Journal of Orthopaedics and Allied Sciences Pub Date : 2015-07-01 DOI: 10.4103/2319-2585.167980

Pradyumna Raval, C. Fhoghlu, A. Mahapatra

引用次数: 1

Anatomical reconstruction of unstable trochanteric fractures through posterior approach 后入路不稳定转子骨折的解剖重建

Journal of Orthopaedics and Allied Sciences Pub Date : 2015-07-01 DOI: 10.4103/2319-2585.158516

P. Saha, S. Ayan, Utpal Bandyopadhyay, A. Mukhopadhyay, Gautam Bhattyacharyya, K. Mukhopadhyay

{"title":"Anatomical reconstruction of unstable trochanteric fractures through posterior approach","authors":"P. Saha, S. Ayan, Utpal Bandyopadhyay, A. Mukhopadhyay, Gautam Bhattyacharyya, K. Mukhopadhyay","doi":"10.4103/2319-2585.158516","DOIUrl":"https://doi.org/10.4103/2319-2585.158516","url":null,"abstract":"Objective Unstable intertrochanteric fractures continue to be a challenge for orthopedic surgeons due to the functional limitations it results in the postoperative period. Anatomical reconstruction of the posteromedial fragment becomes difficult through conventional lateral approach, leading to excessive fracture collapse and limping. Materials and Methods: prospective, nonrandomized study was done with 40 patients. They were operated in prone position through posterior approach. Cancellous screws or SS-wires were used to fix the greater or lesser trochanteric fragments and dynamic hip screw (DHS) or dynamic condylar screw (DCS) for the main two fragments. Bone grafts were used to pack cavities at the posterior trochanteric regions. Results: Fracture healing occurred earlier compared to conventional lateral approach without excessive fracture collapse in majority of cases (average time to achieve union was 13.8 weeks; range: 10–18 weeks). Good functional recovery was noted with 75% 'Good' or 'Excellent' Harris Hip Scores at 24 weeks. Conclusion: Anatomical reconstruction of unstable trochanteric fractures becomes easier through posterior approach with earlier and better functional recovery.","PeriodicalId":31882,"journal":{"name":"Journal of Orthopaedics and Allied Sciences","volume":"3 1","pages":"55 - 58"},"PeriodicalIF":0.0,"publicationDate":"2015-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70434728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

High signal intervertebral disc in T1-weighted magnetic resonance imaging 高信号椎间盘t1加权磁共振成像

Journal of Orthopaedics and Allied Sciences Pub Date : 2015-07-01 DOI: 10.4103/2319-2585.158519

A. Agrawal, Kishor V. Hegde, Umamaheswara V Reddy, Satish Kumar, Malleswara G. Rao

引用次数: 1

Unusual presentation of osteochondroma (Trevor's disease) 异常表现的骨软骨瘤(特雷弗病)

Journal of Orthopaedics and Allied Sciences Pub Date : 2015-07-01 DOI: 10.4103/2319-2585.167975

Digvijay Agarwal, R. Maheshwari, A. Agrawal

引用次数: 0

Effects of platelet-rich plasma in supraspinatus tendinopathy 富血小板血浆在冈上肌腱病中的作用

Journal of Orthopaedics and Allied Sciences Pub Date : 2015-07-01 DOI: 10.4103/2319-2585.167981

P. Singh, N. Saxena, Sohael M. Khan

引用次数: 2

Primary intraosseus meningioma of the calvarium presenting as solitary osteolytic lesion 颅骨原发性骨内脑膜瘤表现为孤立性溶骨损伤

Journal of Orthopaedics and Allied Sciences Pub Date : 2015-07-01 DOI: 10.4103/2319-2585.167977

Kanika Mehta, V. Mohan, A. Munshi, R. Sehrawat

引用次数: 1