MD-Onco最新文献

{"title":"A case of successful combination treatment of a patient with myeloma and acute diverticulitis. Clinical observation","authors":"A. Rasulov, J. Madyarov, Z. Rasulov, A. E. Kulikov, P. A. Zeynalova, Yu. E. Ryabukhina, O. I. Timofeeva, F. М. Abbasbeyli, N. Kupryshina, V. E. Gruzdev, M. A. Anisimov, V. Sarzhevskiy","doi":"10.17650/2782-3202-2021-1-1-55-60","DOIUrl":"https://doi.org/10.17650/2782-3202-2021-1-1-55-60","url":null,"abstract":"","PeriodicalId":318498,"journal":{"name":"MD-Onco","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114699147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Experience in treatment of glial tumors using the CyberKnife device","authors":"E. V. Safronova, A. A. Fedorova, M. N. Demina","doi":"10.17650/2782-3202-2021-1-1-73-78","DOIUrl":"https://doi.org/10.17650/2782-3202-2021-1-1-73-78","url":null,"abstract":"The study objective is to determine the effectiveness of stereotactic radiotherapy in treatment of glial cerebral tumors.Materials and methods. Results of using stereotactic radiotherapy in treatment of recurrent cerebral gliomas in 30 patients and primary glial tumor in 1 patient who couldn’t receive traditional radiotherapy were analyzed. Treatment was administered both to adults (n = 22) and children (n = 9). Prior to treatment all patients underwent pre-radiotherapy preparation in the form of contrast-enhanced magnetic resonance topometry of the brain, computed tomography with topometry, as well as positron emission tomography/computed tomography with amino acids (n = 21).Results. During treatment 2 patient developed grade II toxic reactions requiring emergency medical help. In 29 patients, treatment did not cause any complications. At the time of article preparation, 7 patients were alive; maximal follow-up period was 55 months, median follow-up duration was 8 months.Conclusion. Stereotactic radiotherapy can be used for disease stabilization. The results show effectiveness and safety of stereotactic radiotherapy as a salvage method of local treatment in patients with recurrent glial tumors of the brain.","PeriodicalId":318498,"journal":{"name":"MD-Onco","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115080025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A case of successful treatment of a female patient with ALK-positive inflammatory myofibroblastic tumor of the greater omentum","authors":"J. Madyarov, A. Polynovskiy, I. S. Tatayev, S. Berdnikov, K. Petrov, Z. Rasulov, A. E. Kulikov, A. Rasulov","doi":"10.17650/2782-3202-2021-1-1-43-49","DOIUrl":"https://doi.org/10.17650/2782-3202-2021-1-1-43-49","url":null,"abstract":"","PeriodicalId":318498,"journal":{"name":"MD-Onco","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125877539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perforation of the colon, diffuse septic fibrinous peritonitis in a patient with diffuse large B-cell lymphoma. Clinical observation","authors":"M. M. Davydov, P. A. Zeynalova, E. Glukhov, Yu. E. Ryabukhina, O. I. Timofeeva, A. A. Filatov, M. Shogenov, A. G. Zhukov, V. E. Gruzdev, M. A. Anisimov","doi":"10.17650/2782-3202-2021-1-1-51-54","DOIUrl":"https://doi.org/10.17650/2782-3202-2021-1-1-51-54","url":null,"abstract":"","PeriodicalId":318498,"journal":{"name":"MD-Onco","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131889646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of ultrasound examination in evaluation of the size and advancement of laryngeal and hypopharyngeal tumors to the neighboring anatomical structures","authors":"G. Allakhverdiyeva, A. Mudunov, P. A. Zeynalova, T. Danzanova, A. Batsev","doi":"10.17650/2782-3202-2021-1-1-22-31","DOIUrl":"https://doi.org/10.17650/2782-3202-2021-1-1-22-31","url":null,"abstract":"The study objective is to establish the capabilities of ultrasound (US) examination in evaluation of the advancement of squamous-cell carcinoma of the larynx and hypopharynx compared to histological examination and other diagnostic methods.Materials and methods. US examination was performed in 86 patients with squamous-cell carcinoma of the larynx and hypopharynx. The study included 14 (16.3 %) patients with stage I disease, 29 (33.7 %) patients with stage II, 19 (22.1 %) patients with stage III and 24 (27.9 %) patients with stage IV. Patients with primary tumors of the larynx and hypopharynx comprised 75.6 % of the study population, patients with recurrent tumors – 24.4 %. During diagnosis advancement of tumors to the anatomical structures in the laryngeal space and beyond was evaluated. In all cases histological verification of the diagnosis was performed. Comparison of the data on advancement of laryngeal and hypopharyngeal tumors from different diagnostic methods with the results of histological examination depending on the T-category (TNM) was performed.Results. For small tumors (Т1), frequency of agreement between advancement of laryngeal and hypopharyngeal tumors measured by US examination and histological examination was 66.7 %, by endoscopic laryngoscopy (ELS) – 80.0 %; for T2 tumors, results of US examination and ELS were identical, frequency of agreement with histological examination data was 87.2 % for both methods; for T3 tumors, US examination data agreed with histological examination data in 83.3 % of cases, ELS data – in 75.0 %; for T4 tumors, frequency of agreement between US examination and histological examination data was only 44.4 %, between ELS and histological examination – 66.7 %. Therefore, US examination was more accurate for evaluation of advancement of T2 and T3 tumors. Results of evaluation of advancement of laryngeal and hypopharyngeal tumors by US examination, computed tomography and magnetic resonance tomography were close, comparable and weren’t statistically different. For T1 and T2 tumors frequency of agreement between the results of histological examination and US examination data was higher than between the results of histological examination and computed tomography data.Conclusions. High accuracy and value of US examination in evaluation of advancement of primary and recurrent tumors of the larynx and hypopharynx were shown.","PeriodicalId":318498,"journal":{"name":"MD-Onco","volume":"146 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114505799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical observation of locally advanced thyroid cancer","authors":"A. M. Мudunov, M. M. Davydov, A. Batsev, F. S. Кamolova","doi":"10.17650/2782-3202-2021-1-1-32-37","DOIUrl":"https://doi.org/10.17650/2782-3202-2021-1-1-32-37","url":null,"abstract":"","PeriodicalId":318498,"journal":{"name":"MD-Onco","volume":"58 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115405504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"BRAF-mutant melanoma of the skin during pregnancy with dichorionic diamniotic twins. Clinical case","authors":"M. Davydov, P. A. Zeynalova, A. Fedenko, D. A. Chekiny, E. K. Ibragimov, A. A. Filimonov, O. Sinitsyna, E. Bogush, M. Chekalova, G. Allakhverdieva, M. V. Shamanova, I. V. Zhguleva, V. Y. Kirsanov, V. Ponomarev, S. Polikarpova, T. Valiev, M. A. Kurtser","doi":"10.17650/2782-3202-2021-1-1-38-42","DOIUrl":"https://doi.org/10.17650/2782-3202-2021-1-1-38-42","url":null,"abstract":"Per the majority of authors, melanoma is the most common tumor diagnosed during pregnancy (31 % of all malignant neoplasms). In approximately 1/3 of women melanoma developed in child-bearing age is diagnosed during pregnancy or in the postpartum period. However, only some retrospective studies analyzed the effect of pregnancy on melanoma development, and conclusive data on development, progression and treatment of BRAF-mutant melanoma is lacking. In this subpopulation of patients, BRAF status supposedly can negatively affect disease outcome irrespective of treatment methods.The article presents a clinical case of recurrence of melanoma with the BRAF V600E mutation during pregnancy. The patient underwent lymph node dissection during pregnancy prolongation, after labor she received antitumor drug therapy with МЕК and ВRAF inhibitors. Melanoma recurrence during pregnancy did not worsen treatment outcomes for the mother and embryo.","PeriodicalId":318498,"journal":{"name":"MD-Onco","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125760289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}