Edelweiss: Cancer Open Access最新文献

Imbuing the Supply Chain with the Customers Mind: Todays Reality, Tomorrows Opportunity 为供应链注入客户的思想:今天的现实，明天的机会

Edelweiss: Cancer Open Access Pub Date : 2019-11-04 DOI: 10.33805/2576-8484.170

Moskowitz Howard, Gere Attila, Danny Moskowitz Yeshaya, Sherman Robert, Deitel Yehoshua, Nagarajan Divya, Papajorgji Petraq

引用次数: 2

Recurrence and Mortality Rates Among Receivers and Decliners of Conventional Adjuvant Breast Cancer Treatments 乳腺癌常规辅助治疗的接受者和放弃者的复发率和死亡率

Edelweiss: Cancer Open Access Pub Date : 2019-10-21 DOI: 10.33805/2689-6737.108

Eunjung Kim, L. Standish, M. Andersen

{"title":"Recurrence and Mortality Rates Among Receivers and Decliners of Conventional Adjuvant Breast Cancer Treatments","authors":"Eunjung Kim, L. Standish, M. Andersen","doi":"10.33805/2689-6737.108","DOIUrl":"https://doi.org/10.33805/2689-6737.108","url":null,"abstract":"Objectives:\u0000This paper compared Recurrence and Morality rates among women with breast cancer who received all recommended treatment (Receivers) and who did not (Decliners).\u0000Methods:\u0000427 women were recruited through integrative oncology clinics and the Cancer Surveillance System (CSS) registry in Western Washington State. Secondary data analysis were conducted using descriptive statistics, t-tests, X2 tests, and R. Self-reported data included household income and comorbidity; medical records included dates of diagnosis, recurrence and last visit with medical oncologist; and CSS registry data included demographic, disease characteristics, and records on recommended treatments and receiving/declining them, and date of death.\u0000Results:\u00009% of Receivers and 2% of Decliners experienced a Disease Free Survival (DFS) limiting event commonly a recurrence, while 3% of Receivers and 2% of Decliners died. After controlling for stage at diagnosis and cohort, no difference was found on the Adjusted Hazard ratio of recurrence or mortality between Receivers and Decliners. Adjusted Hazard ratio of Decliners relative to Receivers was 0.29 (95% CI; 0.04 – 2.22, p = 0.22) for DFS and 0.50 (95% CI: 0.04, 6.49, p = 0.59) for mortality.\u0000Conclusions:\u0000Better clinical predictors among Decliners may be related to no rate difference in recurrence and mortality between Decliners than Receivers.","PeriodicalId":316427,"journal":{"name":"Edelweiss: Cancer Open Access","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128544917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Routine Colonoscopy after Diverticulitis Should not be Performed to Rule Out Colorectal Cancer 憩室炎后不应进行常规结肠镜检查以排除结直肠癌

Edelweiss: Cancer Open Access Pub Date : 2019-10-21 DOI: 10.33805/2689-6737.107

Dijkhorst Pj, Loffeld Rjlf

{"title":"Routine Colonoscopy after Diverticulitis Should not be Performed to Rule Out Colorectal Cancer","authors":"Dijkhorst Pj, Loffeld Rjlf","doi":"10.33805/2689-6737.107","DOIUrl":"https://doi.org/10.33805/2689-6737.107","url":null,"abstract":"Introduction: Diverticulitis is a clinical diagnosis generally confirmed by a radiological examination. Guidelines recommend routine screening for colorectal cancer after the acute phase.\u0000Aim: Patients diagnosed with diverticulitis were studied in order to gain more information on presence of concomitant abnormalities. Material and methods: Inclusion criterion was the radiologic diagnosis of diverticulitis. All consecutive requests for ultrasound and/ or CT-scan of the abdomen in a three year period, with Diverticulitis mentioned in application were included. If diverticulitis was diagnosed, than this specific investigation was included in the present study. Hospital records were searched for the presence of endoscopic investigation. Results: In the three year period 1410 consecutive ultrasound investigation and/or CT-scans of the abdomen were performed. After exclusions 198 patients remained with the radiological confirmed diagnosis of diverticulitis. Of these patients 127 (64%) underwent an additional endoscopy. Seventy one patients (36%) did not undergo a colonoscopy. There was no difference in gender or in age between both groups. Colonoscopy showed additional abnormalities in 22 (17.3%) of the patients. These were hyperplastic polyp(s) in six, adenomatous polyp(s) in nine, polyps without histological confirmation in three and segmental colitis in three. Two male patients were diagnosed with sigmoid cancer. Both had non-subsiding diverticulitis with abscess formation at the location of the tumor. Conclusion: It is safe to omit colonoscopy after an episode of uncomplicated diverticulitis. Only in cases of complications or persistent complaints cancer should be part of the differential diagnosis and a subsequent colonoscopy should be performed.","PeriodicalId":316427,"journal":{"name":"Edelweiss: Cancer Open Access","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121132416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Frozen Section Assessment of Bronchial Margins during Lung Carcinoma Surgeries: Report of the Experience at a Single Institution 肺癌手术中支气管边缘的冰冻切片评估:一个机构的经验报告

Edelweiss: Cancer Open Access Pub Date : 2019-07-24 DOI: 10.33805/2689-6737.106

Siba El Hussein, Roy F. Williams, J. Alexis

{"title":"Frozen Section Assessment of Bronchial Margins during Lung Carcinoma Surgeries: Report of the Experience at a Single Institution","authors":"Siba El Hussein, Roy F. Williams, J. Alexis","doi":"10.33805/2689-6737.106","DOIUrl":"https://doi.org/10.33805/2689-6737.106","url":null,"abstract":"Introduction Many thoracic surgeons consider frozen section analysis of bronchial margins during lobectomies “obligatory” although routine frozen section analysis of the bronchial margin rarely yields positive results and infrequently changes intra-operative management in patients undergoing Non-Small Cell Lung Carcinoma (NSCLC) resection. Materials and methods 234 cases of lobectomies with carcinoma were reviewed at our institution to assess bronchial margin involvement, correlation between frozen section and final bronchial margin status, gross distance between tumor and margin, and tumor type. Results Tumor distance to margin varied in the 234 cases from grossly involved to 10 cm away. 5 cases out of 234 (approximately 2.1%) had a positive bronchial margin in the final report. 3 out of the 5 cases were poorly differentiated squamous cell carcinoma grossly abutting the bronchial margin, two cases were of poorly differentiated adenocarcinoma located grossly 0.5 cm away from the bronchial margin. 4 out of 5 cases were called positive intra-operatively. In none of the 4 out of the 5 positive cases did frozen section exam of the bronchial margins change the intra-operative management of the case. Conclusion Our study supports selective use of intra-operative frozen section of bronchial margins during lobectomies for carcinoma. On the basis of our findings, a distance of approximately 1 cm or less is suggested as a threshold for intra-operative microscopic examination of the bronchial margins. However, routine examination of the bronchial margins, regardless of the location of the tumor upon gross examination, and in the absence of empirical evidence supporting this practice, is only time consuming intra-operatively, wasteful of resources and has no therapeutic or prognostic value.","PeriodicalId":316427,"journal":{"name":"Edelweiss: Cancer Open Access","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122192343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Screening for Prostate Cancer: To Screen or Not To Screen? A Review of The State-of-The Art 前列腺癌筛查:筛查还是不筛查?技术现状综述

Edelweiss: Cancer Open Access Pub Date : 2019-01-30 DOI: 10.33805/2689-6737.105

L. Döbrőssy

引用次数: 0