Revista Medica Clinica Las Condes最新文献_第9页

Asma y embarazo: fisiopatología, diagnóstico y manejo farmacológico 哮喘与妊娠：病理生理学、诊断和药物治疗

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Revista Medica Clinica Las Condes Pub Date : 2024-05-01 DOI: 10.1016/j.rmclc.2024.05.001

Paulina Barría

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Enfoque diagnóstico en el paciente con derrame pleural 胸腔积液患者的诊断方法

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Revista Medica Clinica Las Condes Pub Date : 2024-05-01 DOI: 10.1016/j.rmclc.2024.05.010

Maite Oyonarte W.

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Uso correcto de inhaladores en adultos: del conocimiento a la aplicación 成人正确使用吸入器：从认知到应用

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Revista Medica Clinica Las Condes Pub Date : 2024-05-01 DOI: 10.1016/j.rmclc.2024.07.002

Carlos Horta , Loreto Sáez , Jorge Jorquera

{"title":"Uso correcto de inhaladores en adultos: del conocimiento a la aplicación","authors":"Carlos Horta , Loreto Sáez , Jorge Jorquera","doi":"10.1016/j.rmclc.2024.07.002","DOIUrl":"10.1016/j.rmclc.2024.07.002","url":null,"abstract":"<div><p>The administration of drugs via inhalation has become the primary route for treating obstructive pulmonary diseases. In this context, the efficient deposition of medication particles in the airway plays a fundamental role in the effectiveness of inhaled therapy, offering superior benefits in terms of speed and reduction of systemic effects compared to other routes of administration. It is crucial to ensure that a sufficient amount of medication reaches beyond the oropharyngeal region to guarantee therapeutic effectiveness. Among the available devices for this form of administration, pressurized metered-dose inhalers (pMDIs) and dry powder inhalers (DPIs) are the most commonly used. It is worth mentioning that nebulization devices are not covered in this review.</p><p>Although the diversity of therapeutic options is beneficial, the availability of different devices can create some complexity when instructing patients on their proper use. Consequently, it is vital for patients to precisely follow the recommended inhalation technique. Errors in device handling can lead to improper drug distribution, reducing the effective dose and compromising treatment efficacy. This review provides detailed explanations of the mechanism of action of these devices, as well as practical instructions for patient care personnel. Emphasis is placed on the importance of correct inhalation technique to maximize treatment efficacy and ensure optimal drug use.</p></div>","PeriodicalId":31544,"journal":{"name":"Revista Medica Clinica Las Condes","volume":"35 3","pages":"Pages 190-200"},"PeriodicalIF":0.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0716864024000518/pdfft?md5=e855c06c6391ddb92c081ad2cf65c13a&pid=1-s2.0-S0716864024000518-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142011929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Neumonía grave por Influenza H1N1 ¿qué aprendimos desde el 2009? 重症甲型 H1N1 流感肺炎：自 2009 年以来我们学到了什么？

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Revista Medica Clinica Las Condes Pub Date : 2024-05-01 DOI: 10.1016/j.rmclc.2024.07.005

Felipe Reyes-Cartes , Claudio Pérez-Oliva , Andrés Ramos-Plata

引用次数: 0

Enfermedades reumatológicas y compromiso pulmonar, lo que hay que saber 风湿病与肺部受累，您需要了解的知识

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Revista Medica Clinica Las Condes Pub Date : 2024-05-01 DOI: 10.1016/j.rmclc.2024.05.005

Silvana Saavedra , Felipe Reyes-Cartes

{"title":"Enfermedades reumatológicas y compromiso pulmonar, lo que hay que saber","authors":"Silvana Saavedra , Felipe Reyes-Cartes","doi":"10.1016/j.rmclc.2024.05.005","DOIUrl":"10.1016/j.rmclc.2024.05.005","url":null,"abstract":"<div><p>Connective tissue diseases and vasculitis are a wide group of autoimmune pathologies that can affect multiple organs. One of the most frequently affected systems is the respiratory system, with compromise of the airway, lung parenchyma, pleura and mediastinum. These pathologies constitute an important cause of morbimortality, making it essencial to maintain a high clinical suspicion.</p><p>Furthermore, it is of vital relevance to rule out other causes of affectation like adverse drug reactions and infections due to the immunosuppressed state of patients with rheumatic diseases.</p><p>Both the classification and its management must be done by a multidisciplinary team, based on the clinical history, serology, lung function tests, high-resolution computed tomography, bronchoalveolar lavage and/or biopsy, depending on each case.</p><p>This review article aims to highlight the importance of a multidisciplinary approach in the management of connective tissue diseases and vasculitis; complex pathologies that can affect the respiratory system, constituting an important cause of morbidity and mortality. The classification and management of these conditions should be carried out by a multidisciplinary team, based on clinical status, laboratory tests, pulmonary function tests, imaging studies, and biopsies, according to each case.</p></div>","PeriodicalId":31544,"journal":{"name":"Revista Medica Clinica Las Condes","volume":"35 3","pages":"Pages 262-272"},"PeriodicalIF":0.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0716864024000361/pdfft?md5=da14d1812ed9d524b9f31801ed58e7d4&pid=1-s2.0-S0716864024000361-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142012898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cómo calificar el índice de gravedad en la apnea obstructiva del sueño 如何评定阻塞性睡眠呼吸暂停的严重程度指数

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Revista Medica Clinica Las Condes Pub Date : 2024-05-01 DOI: 10.1016/j.rmclc.2024.05.006

Gonzalo Labarca , Mario Henríquez-Beltrán

引用次数: 0

Terapia farmacológica de primera línea en cesación tabáquica 戒烟的一线药物疗法

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Revista Medica Clinica Las Condes Pub Date : 2024-05-01 DOI: 10.1016/j.rmclc.2024.07.001

María Guacolda Benavides

{"title":"Terapia farmacológica de primera línea en cesación tabáquica","authors":"María Guacolda Benavides","doi":"10.1016/j.rmclc.2024.07.001","DOIUrl":"10.1016/j.rmclc.2024.07.001","url":null,"abstract":"<div><p>The current standard for smoking cessation is combined psychological and pharmacological treatment. Administering a drug to stop smoking in isolation (8-10% abstinence per year) is not the same as using it together with support and behavioral intervention (more than 30% abstinence). The fundamental reason drugs are used in the process of quitting smoking is because it has been proven that their use not only mitigates withdrawal symptoms but also increases long term quit rates (6-12 months). Varenicline, nicotine replacement therapy (NRT), bupropion and cytisine are all more effective than placebo. In very dependent smokers, a combination of drugs is recommended, with those associations containing varenicline being more effective. In special populations (chronic respiratory diseases, cardiovascular diseases or psychiatric pathology), varenicline alone or combined with NRT is recommended as the first option. Finally, it is important to highlight that the fact that a previous unsuccessful attempt to stop smoking with a certain drug is not a contraindication for its subsequent use since success depends on many factors, such as; correct usage of the drug, motivational stage, presence of environmental obstacles and a firm decision to quit smoking, among others.</p></div>","PeriodicalId":31544,"journal":{"name":"Revista Medica Clinica Las Condes","volume":"35 3","pages":"Pages 161-168"},"PeriodicalIF":0.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0716864024000506/pdfft?md5=e0ccbfe3abbba6bbfd90321e4d122aef&pid=1-s2.0-S0716864024000506-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142011926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tuberculosis: estado actual 结核病：现状

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Revista Medica Clinica Las Condes Pub Date : 2024-05-01 DOI: 10.1016/j.rmclc.2024.06.001

Juan Carlos Rodríguez-Duque

引用次数: 0

Actualizaciones clínicas en enfermedades pulmonares intersticiales: estrategias diagnósticas y terapéuticas avanzadas 间质性肺病的临床最新进展：先进的诊断和治疗策略

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Revista Medica Clinica Las Condes Pub Date : 2024-05-01 DOI: 10.1016/j.rmclc.2024.05.004

Felipe Reyes-Cartes

{"title":"Actualizaciones clínicas en enfermedades pulmonares intersticiales: estrategias diagnósticas y terapéuticas avanzadas","authors":"Felipe Reyes-Cartes","doi":"10.1016/j.rmclc.2024.05.004","DOIUrl":"10.1016/j.rmclc.2024.05.004","url":null,"abstract":"<div><p>Interstitial lung diseases (ILDs) are a heterogeneous group of disorders that affect the lung interstitium, characterized by inflammation and/or fibrosis. Historically, they were based on histopathological characteristics of lung biopsies, but with the advancement of high-resolution computed tomography (HRCT), the approach has shifted, allowing for the identification of disease patterns that suggest different etiologies. The classification of ILDs has evolved, and they are currently classified according to etiology, histopathological and/or radiological patterns, and evolutionary course. Idiopathic interstitial pneumonias (IIPs) are a group of ILDs of unknown origin, with idiopathic pulmonary fibrosis (IPF) being the most common within the IIPs. The concept of progressive fibrosing interstitial lung disease (PF-ILD) has been developed, describing a phenotype of ILD with progression despite treatment. Diagnosis is based on a detailed clinical history, physical examination, pulmonary function tests, autoimmune serology, and imaging techniques such as HRCT. Treatment varies according to etiology and may include immunomodulatory or anti-inflammatory therapy, disease-modifying therapy with antifibrotic agents and, in advanced cases, lung transplantation. Medical care should be holistic, including pulmonary rehabilitation, infection prevention, and oxygen therapy. This article aims to provide a clinical update on interstitial lung diseases and comment on advances in diagnostic and therapeutic strategies.</p></div>","PeriodicalId":31544,"journal":{"name":"Revista Medica Clinica Las Condes","volume":"35 3","pages":"Pages 241-254"},"PeriodicalIF":0.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S071686402400035X/pdfft?md5=d576d7b5c16b89c315eb6ae755c40254&pid=1-s2.0-S071686402400035X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142012820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

“El saxofonista” "萨克斯手

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Revista Medica Clinica Las Condes Pub Date : 2024-05-01 DOI: 10.1016/j.rmclc.2024.08.002

引用次数: 0