Majalah Kedokteran Gigi Indonesia最新文献

{"title":"Effect of low-intensity pulsed ultrasound on mast cell degranulation and fibroblast expression on type 2 diabetes mellitus rats wound healing process","authors":"I. Maharani, C. Hasan, Bambang Dwirahardjo, T. Pangestiningsih","doi":"10.22146/majkedgiind.59132","DOIUrl":"https://doi.org/10.22146/majkedgiind.59132","url":null,"abstract":"Impaired wound healing is one of the Diabetes mellitus complications. Low-intensity Pulsed Ultrasound (LIPUS) therapy may accelerate the impaired wound healing. The use of LIPUS therapy in the early inflammatory phase can induce mast cell degranulation, and in the proliferative phase it can increase collagen synthesis by fibroblasts. The purpose of this study was to determine the effects of LIPUS therapy on mast cell degranulation and fibroblastexpression in the healing process of punch biopsy wound in rats with type 2 diabetes mellitus. Twenty-four Sprague dawley (n=24) were designed into type 2 diabetes mellitus by injecting Nicotinamide and Streptozotocin, then divided into six groups: diabetes mellitus without LIPUS (DM3, DM7, DM14) and diabetes mellitus with LIPUS (DML3, DML7, DML14), 4 each, and punch biopsy wounds were made on the dorsal skin. The DML group received LIPUS therapy in the wound area (frequency 3 MHz, intensity 0.5 W/cm2, duty cycle 20%, duration 3 minutes every day for 3 days (DML3), 7 days (DML7), and 14 days (DML14). The wounded tissue area was stained with toluidine blue to observe mast cell degranulation and immunohistochemical type HSP-47 to observe fibroblast expression. Two-Way ANOVA and Post Hoc LSD tests were used to determine the differences in mast cell degranulation and fibroblast expression. The results showed that mast cell degranulation and fibroblast expression in the DML group were higher than in the DM group (table 1). Pearson test showed a correlation between mast cell degranulation and fibroblast expression (p=0.00; r= 0.839). LIPUS therapy increases mast cell degranulation and fibroblast expression in type 2 diabetes mellitus rat model. The higher the mast cell degranulation, the higher fibroblast expressions.","PeriodicalId":31262,"journal":{"name":"Majalah Kedokteran Gigi Indonesia","volume":"141 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76737356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of 35% sodium ascorbate on calcium and phosphorus loss in dentin bleached by 35% hydrogen peroxide","authors":"Tunjung Nugraheni, N. Nuryono, S. Sunarintyas, Ema Mulyawati","doi":"10.22146/majkedgiind.46946","DOIUrl":"https://doi.org/10.22146/majkedgiind.46946","url":null,"abstract":"Post bleaching procedures often have free radicals trapped in dentin tubule and interprismatic enamel, leading to demineralization and denaturation. Sodium ascorbate is an antioxidant substance known to bind residual free radicals to stop demineralization and denaturation. The purpose of the study was to assess the calcium and phosphorus loss from the dentin surface following bleaching by 35% hydrogen peroxide and reversal by 35% sodium ascorbate andthe surface structure of the dentin. Six sound premolars were divided into their crown and root sections, with the crown subsequently being cut into four equal parts to obtain 24 samples. The calcium and phosphorus contents as well as the surface structure of the dentin were assessed using SEM-EDX. These were then divided into four groups, each containing six samples. Group A (control): the samples were bleached by 35% hydrogen peroxide, immersed in an artificial saliva, stored in an incubator at 37 °C for seven days. Group B: the samples were bleached by 35% hydrogen peroxide followed by the application of 35% sodium ascorbate for 5 minutes (once). Group C: the samples were bleached by 35% hydrogen peroxide followed by the applications of 35% sodium ascorbate (twice). Group D: the samples were bleached by 35% hydrogen peroxide followed by the applications of 35% sodium ascorbate (threetimes). The calcium and phosphorus contents as well as the surface structure of the dentin were re-assessed using SEM-EDX at the same locations. The results of one-way ANOVA indicated a difference in the calcium loss in the four treatment groups (p<0.05), but there was no difference in the phosphorus loss. An LSD test showed that there was a difference in the calcium loss between group A and groups C and D or between group B and groups C and D. The dentin tubules in group A were larger than group B, C and D. The frequency of 35% sodium ascorbate application had an effect on the calcium loss and the surface structure in the dentin bleached by 35% hydrogen peroxide.","PeriodicalId":31262,"journal":{"name":"Majalah Kedokteran Gigi Indonesia","volume":"47 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86011104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Herpes-associated erythema multiforme in a postmenopausal woman","authors":"Hendri Susanto, Nurhilailah Nurhilailah, R. Ganesha, Hening Tuti Hendarti, Priyo Hadi","doi":"10.22146/majkedgiind.43299","DOIUrl":"https://doi.org/10.22146/majkedgiind.43299","url":null,"abstract":"Herpes-associated erythema multiforme (HAEM) is an acute inflammatory mucocutaneous disease which is characterized by ulcerative lesion on oral mucous membrane with or without skin involvements. The etiology of erythema multiforme (EM) is probably hypersensitivity reaction to human herpes simplex virus tipe 1 (HSV-1). Lesions on lips with HAEM can be treated by corticosteroid and acyclovir topically and/or orally. The objective of this study wasto report the case of HAEM with painful ulcers accompanying with crust on lips. A 55 years old woman complained painful ulcers with crust on lips since the last five months. She had visited a primary health care service and received several medications such as antibiotic (ciprofloxacin), anti-inflammatory drug (corticosteroid), analgesic (mefenamic acid) but her complaint was never healed completely because it was always recurring. The lesion on her lips got worse when she ate hot and spicy food and after she went out for outdor activities. She had a history of herpes virus infection seven months before but it was completely healed after treated by acyclovir topically and amoxicilin orally. An extra oral examination found black brown crust on her upper lip vermillion, well-demarcated, irregular margin, rough surface, erythematous surrounding area, accompanied with pain. An intra oral examination identified ulcers, yellowish, 4-5 mm in size, well-demarcated, irregular margin, redness in surronding area, accompanied with pain. Acomplete blood count examination, serology test for HSV-1 (IgM and IgG) were taken and the result showed that only IgG was reactive. The therapies given to the patient were topical medications with a combination of corticosteroid, chloramphenicol and moisturizer, followed by methyl prednisolone and acyclovir orally. After 6-week treatment, the lesions were completely healed.Herpes-associated erythema multiforme (HAEM) caused by hypersensitivity reactionto herpes simplex virus type 1 (HSV-1) may have a characteristic of painful ulcers accompanied with crust on the lips. The combination of both anti-inflammatory and antiviral drugs can be a choice for the therapy.","PeriodicalId":31262,"journal":{"name":"Majalah Kedokteran Gigi Indonesia","volume":"73 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88025696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oral health-related quality of life in type 2 diabetic patients of Yogyakarta General Hospital","authors":"D. Agustina, N. Purwanti, L. Hanindriyo, Fimma Naritasari","doi":"10.22146/majkedgiind.43693","DOIUrl":"https://doi.org/10.22146/majkedgiind.43693","url":null,"abstract":"Yogyakarta is a province in Indonesia with the highest prevalence (2.4%) of Diabetes Mellitus (DM). Around 90% of diabetic patients suffer from type 2 DM. Oral manifestations of DM may disturb oral functions which in turn influence oral health - related quality of life (OHRQo)L. This study aimed to evaluate the OHRQoL of type 2 DM outpatients in Yogyakarta General Hospital. The study subjects comprised 50 male outpatients and 32 female outpatients with type 2 DM (40-81 years old). Geriatric Oral Health Assessment Index (GOHAI) and Xerostomia Inventory were used to assess OHRQoL and xerostomia status, respectively. Intraoral examinations comprising periodontal tissue, oral hygiene (OH), coated tongue, and present teeth were performed. There were 49 (59.76%) subjects with low and 33 (40.24%) subjects with high score of GOHAI; 78 (95.12%) with and 4 (4.88%) without periodontal tissue defect; 79 (96.34%) with poor and 3 (3.66%) good OH; 17 (20.73%) with coated tongue >50% and 65 (79.27%) with coated tongue ≤50%; 34 (41.46%) with present teeth <20 and 48 (58.54%) with present teeth ≥20; and 39 (47.56%) with xerostomia and 43 (52.44%) with normal status. Only ‘present teeth’ had a significant contribution to the proportion of GOHAI status in type 2 DM patients in this study (p=0.032). Type 2 DM patients with ≥20 teeth had a more significant proportion of high GOHAI status compared to those with <20 teeth. The majority of type 2 DM outpatients of Yogyakarta General Hospital had poor OHRQoL as reflection of their oral condition that is partly contributed by patients with present teeth <20.","PeriodicalId":31262,"journal":{"name":"Majalah Kedokteran Gigi Indonesia","volume":"os-43 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87235373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of temperature and passive ultrasonic irrigation of EDTA 17% in smear layer removal","authors":"Fitra Nabiila Alfiona, Rr Mahayu Dewi Ariani, Nadia Hardini, Gloria Fortuna","doi":"10.22146/majkedgiind.64026","DOIUrl":"https://doi.org/10.22146/majkedgiind.64026","url":null,"abstract":"Smear layer removal in root canal treatment is required to aid the diffusion of intracanal medicament and help sealer penetrate into dentinal tubules. The need for irrigants is important to facilitate smear layer removal in the root canal. Various methods have been proposed in some articles, but their application in apical third still challenges many clinicians due to the complexity of the root canal. This study aimed to analyze the effect of temperature and passive ultrasonic irrigation (PUI) activation of EDTA 17% solution in smear layer removal. Twenty-four extracted mandibular premolars were decoronated to standard root length of 14 mm. The preparation of root canals was completed with crown-down technique using ProTaper FHU to file F3 (30/.09). The root canal irrigation was done with NaOCl 5.25% and EDTA 17% solution. The samples were divided into four groups, namely 25 ºC of EDTA 17% solution (group 1), 37 ºC of EDTA 17% solution (group 2), 25 ºC of EDTA 17% solution with PUI activation (group 3), and 37 ºC of EDTA17% solution with PUI activation (group 4). Smear layer removal was observed under scanning electron microscopy (SEM) and scored ordinally from 1-5. Non-parametric Friedman test showed significant results in all the groups (p<0.05). Post hoc Wilcoxon Signed Rank test showed significant results between group 2 and group 3 (p = 0.039), and between group 3 and group 4 (p = 0.038). The combination methods of temperature and PUI activation showed a significant result in smear layer removal.","PeriodicalId":31262,"journal":{"name":"Majalah Kedokteran Gigi Indonesia","volume":"40 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91203945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of panoramic mandibular cortical bone quality indexes in amlodipine users and healthy individuals","authors":"Aga Satria Nurrachman, L. Epsilawati, A. Azhari, Suhardjo Sitam","doi":"10.22146/majkedgiind.48490","DOIUrl":"https://doi.org/10.22146/majkedgiind.48490","url":null,"abstract":"Hypertension and osteoporosis are believed to be linked to to each other. Previous studies have suggested that the imbalance of calcium metabolism in hypertensive condition and the use of calcium channel blockers such as amlodipine may lower the density and quality of bone. Panoramic radiography has been widely used as a reliable tool in assessing bone quality. One indicator of bone quality in panoramic radiograph is the macrostructure evaluation of mandibular cortical bone by using various indexes such as mandibular cortical index (MCI) and antegonial index (AI). This research aimed to compare the bone quality of hypertensive patients with amlodipine and healthy individuals using MCI and AI. In this study we used sixty panoramic radiographs of hypertensive patients with amlodipine and healthy individuals, thirty for each group, with various aspects of demography. The MCI analysis was done by dividing the mandibular cortical shape into three different qualitative categories and the AI analysis was done quantitatively by measuring the width of mandibular cortical bone in antegonial region using ImageJ software. There were statistically significant differences in the results between the two groups in terms of both AI (p = 0.000) and MCI (p = 0.001) in which hypertensive group had lower score. Based on this research, there were differences of mandibular bone quality of hypertensive patients with amlodipine and healthy individuals, particularly in its macrostructure.","PeriodicalId":31262,"journal":{"name":"Majalah Kedokteran Gigi Indonesia","volume":"66 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74120776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Co-Cr alloy recasting on the fracture toughness","authors":"Resti Efrata Eka, R. Dharmastiti, Widjijono Widjijono","doi":"10.22146/majkedgiind.53689","DOIUrl":"https://doi.org/10.22146/majkedgiind.53689","url":null,"abstract":"Frame denture generally uses Co-Cr alloy. However, alloy is expensive, so dental laboratories use residual sprue casting for recasting. The purpose of this study was to determine the effect of Co-Cr alloy recasting on fracture toughness. This was a laboratory experiment, with five sample groups, namely R0: 100% of new alloys; R1: 50% one-time recasting procedure and 50% new alloys, R2: 50% two-time recasting procedure and 50% new alloys, R3: 50% three-time recasting procedure and 50% new alloys, R4: 50% four-time recasting procedure and 50% new alloys. Fracture toughness was tested using a universal testing machine; the data were analyzed by One-Way Anova test and LSD (p>0.05). The results showed that the fracture toughness was 233.103 MPa-m1/2 in R4, and the highest was 242.435 MPa-m1/2 in R0. The results of the analysis by the LSD test on fracture toughness showed that there were no significant differences in R0 with R1 and R2, but there were significant differences between R0 with R3 and R4. There was a decrease after recasting in each group because of the missing elements of the Co-Cr alloy. The percentage of each element decreased due to oxidation and evaporation during heating. There was a change in the composition of the Co-Cr alloy in R3 and R4. There was a decrease in the fracture toughness. Variation in recasting frequency of Co-Cr alloy affected the fracture toughness. In each sample groups, the fracture toughness of Co-Cr alloy decreased after recasting.","PeriodicalId":31262,"journal":{"name":"Majalah Kedokteran Gigi Indonesia","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82960438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reference values for Down’s cephalometric analysis in Papuans","authors":"Shella Indri Novianty, Budi Suhartono","doi":"10.22146/majkedgiind.63529","DOIUrl":"https://doi.org/10.22146/majkedgiind.63529","url":null,"abstract":"The asessment of cranio-facial structures forms a part of orthodontic diagnosis and treatment. One of the most frequently used cephalometric analysis is the Down’s analysis. It consists of 10 parameters of which 5 are skeletal and 5 are dental. Down has based his findings on 20 Caucasians, which have physical characteristic differences with Papuans. Indigenous Papuans are people of Melanesian descent consisting of indigenous tribes in Papua province and/or people who are accepted and recognized as Papuans by indigenous Papuans.The use of cephalometric values in different racial types, may result in the incorrect orthodontic diagnosis and treatment plan. According to those, the objectives of this study are to determine reference values for Down’s cephalometric analysis in papuans, to evaluate the differences exists between Papuan adult male and female, and also to compare the mean difference between persent study and established value of Down’s norms. A study was conducted on 16 lateral cephalograms of Papuans that have been selected based on inclusion criteria. The Down’s method was used for the cephalometric analysis. The data obtained was processed statistically to determine the mean, standart deviation, and minimum-maximum value, and presented in the form of frequency, table, or diagram. The result showed that the normal cephalometric values of papuans different from the normal values used in the Down’s analysis. The values obtained in this research is expected to be a reference in conducting Down’s cepahlometric analysis in Papuans for orthodontic treatment purposes.","PeriodicalId":31262,"journal":{"name":"Majalah Kedokteran Gigi Indonesia","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81303566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The correlation of zinc serum levels and zinc intake with taste disorders in elderly patients at Babatan Public Health Center Bandung","authors":"Rahmatia Djou, D. M. D. Herawati, T. Dewi","doi":"10.22146/majkedgiind.63840","DOIUrl":"https://doi.org/10.22146/majkedgiind.63840","url":null,"abstract":"Taste disorders, which can be caused by various factors, including deficiency of zinc levels in the body and lack of zinc, generally occur in the elderly. The aim of the study was to analyze the correlation between zinc serum levels and zinc intake, as well as the correlation between salivary volume, hypertension, and smoking with taste disorders in the elderly. This was analytical observational research with a cross-sectional method, which was conducted on 100 elderly patients, at Babatan Health Community Center, Bandung, Indonesia. The sampling was conducted through the following: interview about systemic disease history, drugs taken, and smoking habits; examination of oral cavity conditions; nutrition intake interviews; taste tests tests; and zinc serum measurement using the atomic absorption spectrometry. The data were obtained statistically. Among these one hundred elderly patients, 79 had low zinc serum levels and 94 had inadequate zinc intake. The average zinc serum in the elderly patients with taste disorders was 40.1 μg/dl, whereas those without taste disorders was 72.4 μg/dl, with a p value of <0.001. The average zinc intake in the elderly patients with taste disorders was 3.4, whereas in those without taste disorders was 6.0, with a p value of <0.027. Smoking correlated with taste disorders, while salivary volume and hypertension had no a correlation with taste disorders. There was correlation between zinc serum levels and zinc intake on taste disorders in the elderly patients. Smoking had a relationship with taste disorders in the elderly patients, whereas salivary volume and hypertension had no correlation with taste disorders in the elderly patients.","PeriodicalId":31262,"journal":{"name":"Majalah Kedokteran Gigi Indonesia","volume":"64 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90239086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The cariogenic effect of school snack on risk levels with caries assessment tool study in children age 12-15 years old","authors":"Yulita Subandari, B. Priyono, A. Supartinah","doi":"10.22146/majkedgiind.58950","DOIUrl":"https://doi.org/10.22146/majkedgiind.58950","url":null,"abstract":"The teen years, around the age of 12-14 years, is the time for children to experience physical growth spurt, which increases their appetite, so they love snacks and develop snack eating habit at school. This study aims to determine the cariogenic effect of school snacks on caries risk based on the caries assessment tool (CAT) study in children aged 12-15 years. This is an observational quantitative study with cross-sectional research design. The population in this study were all students of class VII, aged 12-15 years in SMP Negeri (SMPN) Kulon Progo, comprised of 2,047 students. This study used a cluster proportional random sampling technique and obtained a sample size of 100 respondents. Data were collected using a questionnaire about school snacks and observation of caries risk assessment was based on CAT, and the data were analyzed using the Chi-Square test. The results showed that the cariogenic school snacks consumed by children aged 12-15 years in SMPN Kulon Progo were in the low category (71%); risk of caries occurrence based on CAT studies in children aged 12-15 years was in the high category of 50%. There was no significant effect on cariogenic school snacks on the level of caries risk based on CAT study in children aged 12-15 years.","PeriodicalId":31262,"journal":{"name":"Majalah Kedokteran Gigi Indonesia","volume":"124 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83580230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}