Smart Molecules最新文献

A novel sulfur‐containing photoinitiator based on benzophenone derivatives for rapid photopolymerization 基于二苯甲酮衍生物的新型含硫光引发剂的快速光聚合

Smart Molecules Pub Date : 2025-03-28 DOI: 10.1002/smo.20240065

Yu Li, Wenzheng Li, Saihe Yang, Lu Li, Shikun Song, Yuting Tang, Han Han, Zhenyue Duan, Yangyang Xin, Jiangli Fan, Pengzhong Chen, Xiaojun Peng

{"title":"A novel sulfur‐containing photoinitiator based on benzophenone derivatives for rapid photopolymerization","authors":"Yu Li, Wenzheng Li, Saihe Yang, Lu Li, Shikun Song, Yuting Tang, Han Han, Zhenyue Duan, Yangyang Xin, Jiangli Fan, Pengzhong Chen, Xiaojun Peng","doi":"10.1002/smo.20240065","DOIUrl":"https://doi.org/10.1002/smo.20240065","url":null,"abstract":"Abstract In this study, a series of benzophenone (BP)‐based photoinitiators (PIs), designated as BP‐Sn, were synthesized by the integration of small molecule hydrogen donors into the BP scaffold. This design aims to minimize reliance on co‐initiators, reduce potential odors and toxicities, and enhance initiation efficiency of PIs under LED irradiation. Additionally, the incorporation of thioether linkages imparts a distinctive dual functionality to PIs, enabling them to exhibit both hydrogen‐abstracting (Type II) and bond‐breaking (Type I) characteristics. The photophysical and photoinitiation properties of BP‐Sn were evaluated using electron paramagnetic resonance, UV‐visible spectrophotometry, and real‐time Fourier‐transform Infrared spectroscopy. The findings demonstrate that BP‐Sn exhibit remarkable efficacy as a single‐component PI for free‐radical polymerization, achieving a final conversion efficiency approaching 95% and a photoinitiation rate exceeding 20% s −1 for the polymerization of tripropylene glycol diacrylate without the need for additional co‐initiators. Furthermore, the polymerization experiment revealed that exposure to 365 nm LED light for just 2 min results in the formation of a colorless and well‐defined patterned texture, with a thickness of 5 mm and a diameter of 7 cm, demonstrating its potential practical applications.","PeriodicalId":312330,"journal":{"name":"Smart Molecules","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/smo.20240065","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147898661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Strategy for pattern recognition‐driven optical chemosensing based on polythiophene 基于聚噻吩的模式识别驱动型光学化学传感战略

Smart Molecules Pub Date : 2024-06-01 DOI: 10.1002/smo.20240001

Binduja Mohan, Yui Sasaki, Tsuyoshi Minami

引用次数: 0

Capture‐SELEX for a short aptamer for label‐free detection of salicylic acid 捕获SELEX短适配体，用于无标签检测水杨酸

Smart Molecules Pub Date : 2023-08-28 DOI: 10.1002/smo.20230007

Lide Gu, Hanxiao Zhang, Yuzhe Ding, Yaoxuan Zhang, Deli Wang, Juewen Liu

{"title":"Capture‐SELEX for a short aptamer for label‐free detection of salicylic acid","authors":"Lide Gu, Hanxiao Zhang, Yuzhe Ding, Yaoxuan Zhang, Deli Wang, Juewen Liu","doi":"10.1002/smo.20230007","DOIUrl":"https://doi.org/10.1002/smo.20230007","url":null,"abstract":"Salicylic acid (SA) is a hydrolysis product and an active form of aspirin, and SA is found in a range of fruits and other food products. For food and drug and analysis there is a strong desire to detect SA. Since SA is a very small molecule, aptamers have advantages over antibodies for its detection. In this work, we used the library‐immobilization capture‐SELEX method to isolate aptamers for SA. After 17 rounds of selection, two main families of aptamers were isolated. The SA1 aptamer from family 1 has a Kd of 5.8 μM from a thioflavin T (ThT) fluorescence assay and 26.7 μM from isothermal titration calorimetry. The binding of other sequences was weaker compared to SA1. Based on mutation studies, the two conserved regions of SA1 were connected by two stems. Using ThT as a stain, a label‐free fluorescent sensor was tested for the detection of SA with a detection limit of 2.2 μM. A few similar molecules were tested including aspirin, and only p‐hydroxybenzoic acid showed a weak binding, indicating the high specificity of the SA1 aptamer. Finally, the SA1 aptamer was also tested in tomato juice and a similar binding performance was achieved.","PeriodicalId":312330,"journal":{"name":"Smart Molecules","volume":"s1-8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127197911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chemical tags and beyond: Live‐cell protein labeling technologies for modern optical imaging 化学标签及其他:现代光学成像的活细胞蛋白标签技术

Smart Molecules Pub Date : 2023-08-28 DOI: 10.1002/smo.20230002

Dilizhatai Saimi, Zhixing Chen

引用次数: 0

Enhancing tetraphenylethene cyclization as photoswitch 增强四苯乙烯环化作为光开关

Smart Molecules Pub Date : 2023-08-06 DOI: 10.1002/smo.20230003

Yue Wu, Yiran Ren, Xiao-xing Zeng, Honglong Hu, Mengqi Li, Junzi Li, Tingchao He, Xin‐Shun Li, Zhen-Qiang Yu, Wei‐Hong Zhu

{"title":"Enhancing tetraphenylethene cyclization as photoswitch","authors":"Yue Wu, Yiran Ren, Xiao-xing Zeng, Honglong Hu, Mengqi Li, Junzi Li, Tingchao He, Xin‐Shun Li, Zhen-Qiang Yu, Wei‐Hong Zhu","doi":"10.1002/smo.20230003","DOIUrl":"https://doi.org/10.1002/smo.20230003","url":null,"abstract":"Tetraphenylethene (TPE), a star building block with promising aggregation‐induced emission, has received much interest. Given that its intramolecular Woodward‐Hoffmann cyclic intermediate instantaneously converts back to the original state within several picoseconds, the essentially photochromic characteristic of TPE is little investigated. Achieving a visible photocyclization of TPE is still an unsolved issue and considered as the bottleneck in the further advancement of applications. We report a strategy of attaching carbonate ester onto the TPE skeleton (TPE‐4C) to enhance TPE photocyclization stability. As demonstrated, the incorporated cholesteryloxycarbonyloxy substituents in TPE‐4C can increase the energy barrier for cycloreversion, thereby exhibiting extremely thermal stability of photocyclic intermediate upon UV irradiation, prolonging its lifetime from 63 picoseconds to 46 s by 7.2 × 1011‐fold. The photoinduced cyclization of TPE‐4C could be monitored with naked eyes, and the photocyclization/cycloreversion is achieved by turning on/off UV light along with a relative fatigue resistance. Encapsulation of TPE‐4C into the liquid crystal can induce a striking phase transformation (achiral↔chiral), which can be applicable to encode optical information. Employing carbonate ester into the TPE unit plays a vital role in enhancing the unprecedented TPE photocyclization stability, providing a toolbox to allow TPE‐based photocyclization to be visually monitored.","PeriodicalId":312330,"journal":{"name":"Smart Molecules","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117295930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Smart molecules: Serve today and make the future 智能分子:服务今天，创造未来

Smart Molecules Pub Date : 2023-06-01 DOI: 10.1002/smo.20230005

Xiaojun Peng

引用次数: 1

Photodynamic and photothermal therapies for bacterial infection treatment 光动力和光热疗法治疗细菌感染

Smart Molecules Pub Date : 2023-05-16 DOI: 10.1002/smo.20220010

Heejeong Kim, You Rim Lee, H. Jeong, J. Lee, Xiaofeng Wu, Haidong Li, Juyoung Yoon

引用次数: 5

An acidic medium‐compatible deep‐near‐infrared dye for in vivo imaging 一种酸性介质兼容的深近红外染料，用于体内成像

Smart Molecules Pub Date : 2023-05-16 DOI: 10.1002/smo.20230001

Yan Dong, Ye Zou, X. Jia, Lei Yin, Weiwei He, Xiao Luo, Xuhong Qian, Youjun Yang