The Medical Journal of Goztepe Training and Research Hospital最新文献

{"title":"Evaluation of thoracic manifestations of breast cancer","authors":"I. Ozmen, T. Törün, G. Ataç, E. Aksoy, G. Horzum, Y. Bolukbasi, H. Çalışır, K. Tahaoğlu","doi":"10.5222/J.GOZTEPETRH.2013.198","DOIUrl":"https://doi.org/10.5222/J.GOZTEPETRH.2013.198","url":null,"abstract":"SUMMARY Objectives: Clinical and radiological features of 36 patients with breast cancer were investigated retrospectively. Materials and methods: Patients with breast cancer who had pulmonary complaints and radiologic abnormalities observed during oncology follow-ups were hospitalized, and investigated in clinics of chest disease. Pulmonary lesions were classified into 2 groups; Group I: malignant lesions due to metastasis of breast cancer, and Group II: nonmalignant lesions. Results: The mean age of the patients was 52.4±14.8 (28-93) years. Thirty-four patients were previously diagnosed with unilateral and 2 patients with bilateral ductal breast carcinoma. Twenty seven percent (n=10) of the patients were smokers (mean 10.7±6.81 pack-years). The mean time between the detection of breast cancer and the manifestations of pulmonary symptoms was 57.02±53.83 (3-180) months). The most common radiological abnormality was pleural effusion (n=23;63.9 %). Twenty-seven (75 %) patients had malignant (Group I), and 9 (25 %) patients had nonmalignant (Group II) pulmonary lesions. Malignant histopathology (n=27) was established by pleural fluid cytology in 13 (48.1 %), fiber optic bronchoscopy in 8 (29.6 %), pleural biopsy in 4 (14.8 %), CT guided transthoracic needle aspiration biopsy in 1 (3.7 %) and thoracotomy in 1 (3.7 %) patient, respectively. Mean time interval between the diagnosis of breast cancer and the detection of malignant pleural effusion was 69.91±64.21 (3-180) months. Nine (25 %) patients had nonmalignant pulmonary lesions including pneumonia in 3 (33.3 %), pulmonary thromboembolism and DVT in 3 (33,3 %), tuberculosis in 2 (22.2 %) and pulmonary fibrosis in 1 (11,1 %) patient. Conclusion: Pulmonary manifestations of breast cancer are most commonly related to metastases and can be observed in long time after the diagnosis of breast cancer. Besides, these nonmalignant reasons should be kept in mind and histopathologic confirmation should me made.","PeriodicalId":312011,"journal":{"name":"The Medical Journal of Goztepe Training and Research Hospital","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123109688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pure tone audiometry and otoacoustic emissions in hypertensive subjects","authors":"D. Korkmaz, M. Habeşoğlu, A. Yılmaz, A. Karaaslan, A. Tosun, Ç. Oysu","doi":"10.5222/J.GOZTEPETRH.2013.194","DOIUrl":"https://doi.org/10.5222/J.GOZTEPETRH.2013.194","url":null,"abstract":"CONTACT Systemic hypertension causes changes in many target organs. The presence of stage-2 retinopathy detected by fundus examination is considered to be target organ damage. This damage occurs due to vascular physiodynamic changes (2). The cochlea is one of the target organs involved by HT due to its contents. Assessment of hearing as well as sounds induced by vibrations of the outer hair cells with OAE provides information about cochlear function. Conflicting results were reported by studies examining the effects of HT on the cochlea. Markov M et al delineated HT to be an important risk factor for the cochlea in the study of 50 patients with HT (8). Esparza et al. showed impairment in hearing thresholds in hypertensive patients with retinal vascular damage (4). However, Torre et al. reported no association between hypertension and sensorineural hearing loss in the DPOAE tests (5). Similarly, Parving et al. detected no relevant link between hypertension and hearing loss (9). In a study performed on 80 Wistar rats by Li S et al. it was shown that there were glycogenesis and an abnormal release of neurotransmitters caused by HT, resulting in aging of the cochlea (10). The result of the electrocochleographic tests was reported to be worse in rats with HT as compared with normotansive rats (11). In the literature, it was shown that glutathione, anti-oxidant enzyme, and Nacetyltransferase are found in the cochlea and these two enzymes are genetically scarce in presbyacusis (12). In this context, HT can lead to oxidative stress in the cochlea, thus, resulting in presbycusis. Our study has revealed that there was a significant increase of the subjective complaint of tinnitus in patients with HT compared to the control group. In pure tone audiological assessment, hearing thresholds were 33.08±13.09 and 40.85±19.83 dB at 4000 and 8000 Hz in the HT group, respectively, while 17.25±11.27 and 21.83±14.46 dB were measured in the control group, respectively. Audiometrically, a significant association appeared between presbycusis and HT in our study. The HT group had a statistically significant decrease in responses to DPOAE as compared with the control group at OAE tests performed especially at 6000 Hz frequencies. The results of our study, despite being different from those by Torre et al. were consistent with the ones by Esparza et al. In order to better understand the effect of HT on the cochlea, it is necessary to see the results of further studies on this issue in the literature. 5. Conclusion Systemic hypertension causes changes in a variety of target organs. Vascular physiodynamic changes have been implicated in HT induced target organ damage (2). The cochlea due to its contents vascular physiodynamic mechanisms is one of the target organs on which HT may have an effect. In studies performed so far, there have been conflicting results gained between HT and cochlear symptoms (4,5). Our results strongly suggest that HT can cause cochleopathologic change","PeriodicalId":312011,"journal":{"name":"The Medical Journal of Goztepe Training and Research Hospital","volume":"55 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124462326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Abdominal wall endometriosis after cesarean section: Case report","authors":"S. Kayataş, E. Cogendez, Sevcan Arzu Arınkan, H. Yavuz, E. Kaygusuz","doi":"10.5222/J.GOZTEPETRH.2013.228","DOIUrl":"https://doi.org/10.5222/J.GOZTEPETRH.2013.228","url":null,"abstract":"","PeriodicalId":312011,"journal":{"name":"The Medical Journal of Goztepe Training and Research Hospital","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123593348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antihypertensive therapy-induced pancreatitis","authors":"A. Atay, E. Yorulmaz, Emel Sağlam Gokmen, B. Gullu, D. Sit","doi":"10.5222/J.GOZTEPETRH.2013.136","DOIUrl":"https://doi.org/10.5222/J.GOZTEPETRH.2013.136","url":null,"abstract":"","PeriodicalId":312011,"journal":{"name":"The Medical Journal of Goztepe Training and Research Hospital","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122003919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of rutine radiographical necessity according to Ottawa rules in patients with ankle trauma","authors":"U. Yavuz, S. Sökücü, B. Demir, Merter Yalçınkaya, E. Çetinkaya, M. Coşkun, Y. Kabukcuoglu","doi":"10.5222/J.GOZTEPETRH.2013.204","DOIUrl":"https://doi.org/10.5222/J.GOZTEPETRH.2013.204","url":null,"abstract":"","PeriodicalId":312011,"journal":{"name":"The Medical Journal of Goztepe Training and Research Hospital","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132247154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A rare foreign body in the stomach: A case report","authors":"Barış Gültürk, A. Bozdağ, B. Kanat, M. Girgin, U. Gulacti","doi":"10.5222/J.GOZTEPETRH.2013.213","DOIUrl":"https://doi.org/10.5222/J.GOZTEPETRH.2013.213","url":null,"abstract":"","PeriodicalId":312011,"journal":{"name":"The Medical Journal of Goztepe Training and Research Hospital","volume":"83 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132801574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bronchogenic cysts: A report of two cases","authors":"Esra Akkütük Öngel, G. H. Ekinci, E. Çelik, Osman Hacıömeroğlu, G. Bektemur, M. Kavas, A. Yilmaz","doi":"10.5222/J.GOZTEPETRH.2013.216","DOIUrl":"https://doi.org/10.5222/J.GOZTEPETRH.2013.216","url":null,"abstract":"","PeriodicalId":312011,"journal":{"name":"The Medical Journal of Goztepe Training and Research Hospital","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114742321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Two tuberculosis cases with mass lesion appearance","authors":"Özlem Abakay, H. Şen, F. Meteroğlu, A. C. Tanrıkulu, A. Abakay","doi":"10.5222/J.GOZTEPETRH.2013.141","DOIUrl":"https://doi.org/10.5222/J.GOZTEPETRH.2013.141","url":null,"abstract":"","PeriodicalId":312011,"journal":{"name":"The Medical Journal of Goztepe Training and Research Hospital","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126459504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Results of intensive care treatment in cases with pregnancy induced hypertension","authors":"H. Koçer, M. Karacaoglu, T. Karacan, Dilek Sağlam, H. Dayan, M. Naki","doi":"10.5222/J.GOZTEPETRH.2013.107","DOIUrl":"https://doi.org/10.5222/J.GOZTEPETRH.2013.107","url":null,"abstract":"","PeriodicalId":312011,"journal":{"name":"The Medical Journal of Goztepe Training and Research Hospital","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124942304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"10.5222/J.GOZTEPETRH.2013.186","authors":"E. Tanrıverdi, H. Hasanoğlu","doi":"10.5222/J.GOZTEPETRH.2013.186","DOIUrl":"https://doi.org/10.5222/J.GOZTEPETRH.2013.186","url":null,"abstract":"","PeriodicalId":312011,"journal":{"name":"The Medical Journal of Goztepe Training and Research Hospital","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122482865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}