Dentino Jurnal Kedokteran Gigi最新文献

{"title":"TOXICITY TEST OF CHANNA MICROPELTES EXTRACT BETWEEN NORMAL WISTAR RATS AND DIABETES MODEL BASED ON CARDIAC HISTOPATHOLOGY","authors":"Annisa Noviany, Amy Nindia Carabelly, Juliyatin Putri Utami","doi":"10.20527/dentino.v8i2.17525","DOIUrl":"https://doi.org/10.20527/dentino.v8i2.17525","url":null,"abstract":"Background: DM is metabolic disease can prolong wound healing phase and cause oxidative stress that can affect cardiac damage such as degeneration, hypertrophy, and necrosis. They can be inhibited by the effect of 16 ml/kg BW CM containing palmitic acid (18.30%), albumin (3.6147g/dl), and amino acids are leucine (1.58%) and valine (0.97%). It's proven to accelerate wound healing in normal Wistar rats and DM. However, CM extract on the cardiac is unknown, so an acute toxicity test was carried out for 14 days. Purpose: To analyze the effect of oral administration of CM extract at an effective dose of 16 ml/kg BW on the histopathological exam of degeneration, hypertrophy, and cardiac necrosis of normal Wistar rats and diabetic models. Method: This study is true experimental study with a post-test only control group design which is divided into 4 groups are 2 groups of Wistar rats normal and diabetic models who were given CM extract at an effective dose of 16 ml/kg BW, 2 groups consisted of normal Wistar rats and diabetic models which were only given BR2 feed. Results: T-Independent test and the Mann-Whitney test showed that there was a significant difference between degeneration and hypertrophy (p<0.05) and necrosis. There was no significant difference (p>0.05). Conclusion: The effective dose of CM extract 16 ml/kg BW had an effect on the cardiac of normal Wistar rats and diabetic models in the form of a decrease in the level of damage to degeneration, hypertrophy, and cardiac necrosis. Keywords: Cardiac, Channa micropeltes, Degeneration, Hypertrophy, Necrosis.Background: DM is metabolic disease can prolong wound healing phase and cause oxidative stress that can affect cardiac damage such as degeneration, hypertrophy, and necrosis. They can be inhibited by the effect of 16 ml/kg BW CM containing palmitic acid (18.30%), albumin (3.6147g/dl), and amino acids are leucine (1.58%) and valine (0.97%). It's proven to accelerate wound healing in normal Wistar rats and DM. However, CM extract on the cardiac is unknown, so an acute toxicity test was carried out for 14 days. Purpose: To analyze the effect of oral administration of CM extract at an effective dose of 16 ml/kg BW on the histopathological exam of degeneration, hypertrophy, and cardiac necrosis of normal Wistar rats and diabetic models. Method: This study is true experimental study with a post-test only control group design which is divided into 4 groups are 2 groups of Wistar rats normal and diabetic models who were given CM extract at an effective dose of 16 ml/kg BW, 2 groups consisted of normal Wistar rats and diabetic models which were only given BR2 feed. Results: T-Independent test and the Mann-Whitney test showed that there was a significant difference between degeneration and hypertrophy (p<0.05) and necrosis. There was no significant difference (p>0.05). Conclusion: The effective dose of CM extract 16 ml/kg BW had an effect on the cardiac of normal Wistar rats and diabetic models in the f","PeriodicalId":31189,"journal":{"name":"Dentino Jurnal Kedokteran Gigi","volume":"88 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134903536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"BACTERIAL INFECTIONS-INDUCED ORAL ERYTHEMA MULTIFORME IN A SEPTIC CHILD: A RARE CASE REPORT","authors":"Amira Shafuria, Riani Setiadhi","doi":"10.20527/dentino.v8i2.17528","DOIUrl":"https://doi.org/10.20527/dentino.v8i2.17528","url":null,"abstract":"Background: Sepsis is a medical emergency condition that triggers an immune response due to an infectious process. Causative organisms in sepsis including viruses, bacteria, fungi, and parasites. Microorganism infection is one of the etiologies of erythema multiforme. Objective: This case report was aimed to describe the bacterial infection as a trigger for oral erythema multiforme in a septic child. Case: A 12-years-old boy was referred to the Oral Medicine Department. Extraoral showed a symmetric face and he was using a nasogastric tube. There were erosive lesions and tend to bleed, hemorrhagic crusts on the upper and lower lips. Laboratory test results revealed increasing in leukocyte (15,880/µL), procalcitonin (24.58 ng/mL), and C-reactive protein (3.67 mg/L). The identified microorganisms in pus specimens including gram-positive coccus and gram-negative rods as well as the isolated bacterial colonies were Enterococcus faecalis, Klebsiella pneumoniae, and Citrobacter koseri. The diagnosis was oral erythema multiforme induced by bacterial infections. Case management: The medications given by the Pediatric Department were cefotaxime vial 1 gram, metronidazole 500 mg/100 ml, and paracetamol 1 gr/100 ml. The Oral Medicine Department gave the instructions for compressing the lips with gauze soaked in 0.9% Sodium Chloride solution four times a day to remove crusts and accelerate wound healing. Oral lesions showed significant improvement after 7 days of therapy. Conclusion: Oral erythema multiforme in a pediatric patient could be induced by sepsis of bacterial infection. The microbial infection causes the release of endotoxins that trigger erythema multiforme. Keywords: Bacterial infection, Oral erythema multiforme, Sepsis.","PeriodicalId":31189,"journal":{"name":"Dentino Jurnal Kedokteran Gigi","volume":"59 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134903696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ANTIFUNGAL ACTIVITY OF RAMANIA LEAF EXTRACT (Bouea Macrophylla Griff) AGAINST Candida albicans","authors":"Reski Nurafia, Isyana Erlita, Yusrinie Wasiaturrahmah","doi":"10.20527/dentino.v8i2.17519","DOIUrl":"https://doi.org/10.20527/dentino.v8i2.17519","url":null,"abstract":"Background: Root canal infection is a polymicrobial infection that causes pulpitis or localized pulp inflammation. Root canal infection occurs due to the presence of pathogenic microorganisms in the root canal. One of the most common pathogenic microorganisms found in root canals is the fungus Candida albicans. Treatment that can be done to treat pulp tissue infection is endodontic treatment. Chlorhexidine gluconate 2% is one of the irrigation materials that can be used in root canal treatment. Ramania leaf extract contains compounds such as triterpenoids, phenols, flavonoids, steroids, saponins, alkaloids, and tannins that can function as antifungals. Purpose: Measuring and analyzing the antifungal activity of ramania leaf extract (Bouea Macrophylla Griff) on the growth of Candida albicans. Method: This study is a true experimental study with a post-test-only design with a control group design consisting of 7 treatment groups and repeated 4 times. The antifungal activity was assessed from the inhibition zone formed on Sabouraud Dextrose Agar media by the diffusion method. Results: Based on the Mann-Whitney test showed that there was only 1 pair of groups that did not have a significant difference, namely 100% concentration of ramania leaf extract with 2% chlorhexidine gluconate while the other groups had significant differences from each other. Conclusion: Ramania leaf extract concentrations of 6.25%, 12.5%, 25%, 50%, and 100% had antifungal activity in inhibiting the growth of the fungus Candida albicans. Keywords: Antifungal Activity, Candida albicans, Chlorhexidine gluconate 2%, Ramania Leaf Extract.","PeriodicalId":31189,"journal":{"name":"Dentino Jurnal Kedokteran Gigi","volume":"327 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134903541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"FOURIER-TRANSFORM INFRARED SPECTROSCOPY ANALYSIS OF MAULI BANANA (MUSA ACUMINATA) EXTRACT AS A POTENTIAL PULP WOUND HEALING","authors":"Dewi Puspitasari, Muhammad Yanuar Ichrom Nahzi, Yosi Kusuma Eriwati, Erni Marlina, Maharani Laillyza Apriasari, Maria Tanumihardja, Juliyatin Putri Utami, Amy Nindia Carabelly","doi":"10.20527/dentino.v8i2.17536","DOIUrl":"https://doi.org/10.20527/dentino.v8i2.17536","url":null,"abstract":"Background: Pulp wound healing is a critical aspect of endodontics, aiming to preserve the vitality and function of dental pulp tissues. Natural compounds have gained attention for their potential therapeutic applications in dentistry. Mauli banana (Musa acuminata) is a tropical fruit in South Kalimantan as one of the natural plants that have the ability as antibacterial, antifungal, anti-inflammatory, antioxidant, and immunomodulatory effects contains various bioactive molecules with potential pulp wound healing properties. Purpose: to identify and evaluate the functional groups present in mauli banana stem extracts. Methods: This study is true experimental research, the samples were mauli banana stem that were extracted with maceration technique and were subjected to Fourier-Transform Infrared Spectroscopy test. Results: Identification of functional groups of organic compounds from mauli banana are as follows: a) Peak 3638.95 cm-1 show O-H (nonbonded hydroxy group, OH stretch primary) component alcohol, b) Peak 3265.82 cm-1is C-H (alkane), c) Peak 2928.09 cm-1 refer to OH (carboxylic acid hydrogen bonds) and aldehydes groups, d) peak 1571.35 cm-1 refers to amide, C=O - asymetric stretching, e) peak 1400.82 cm-1, refers to CO2- symetric stretching and carboxylate (carboxylic acid salt) CH2 scissoring, f) peak 1030.17 cm-1 refers to C=C (alkanes), aliphatic phosphate, g) Peak 520.53 cm-1 refers to inorganic phosphates. Conclusion: FTIR spectra analysis of mauli banana stem extract show the presence of O-H hydroxy groups, aldehydes groups, carbonyl groups, aliphatic groups, carbonyl groups, amides groups and C-O stretching vibrations suggests that the extract contains various bioactive molecules with potential pulp wound healing properties.","PeriodicalId":31189,"journal":{"name":"Dentino Jurnal Kedokteran Gigi","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134903704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"DIFFERENCES OF HERBAL AND NON-HERBAL TOOTHPASTE AGAINST DECREASING PLAQUE INDEX OF ADOLESCENT WOMEN","authors":"Siti Almira Rahma, R. Harry Dharmawan Setyawardhana, Nurdiana Dewi","doi":"10.20527/dentino.v8i2.17523","DOIUrl":"https://doi.org/10.20527/dentino.v8i2.17523","url":null,"abstract":"Background: Women had better dental and oral health than men because women had better fine motor skills and manual dexterity than men. Dental and oral health problems commonly found in adolescents were caused by plaque. Plaque is a soft layer tightly attached to the tooth’s surface. Plaque could be cleaned mechanically and chemically by brushing teeth using toothpaste. Toothpaste was divided into two types, namely herbal and non-herbal toothpaste which had ingredients that were efficacious for dental health. Purpose: Analyzing the differences in the effectiveness of herbal and non-herbal toothpaste against decreasing plaque index in adolescent women around 11-19 years at the Aisyiah Hikmah Zam-Zam Orphanage and Harapan Ibu Orphanage, Banjarmasin. Methods: This study used the true experimental method with a pre-and post-test control group design, using simple random sampling. Result: The Wilcoxon test in the herbal toothpaste group obtained a significant value of 0.001 (<0.05) which meant that there was a significant difference between the plaque index before and after using herbal toothpaste, while in the non-herbal toothpaste group a significant value of 0.124 (>0.05) which meant that there was no significant difference between the plaque index before and after using non-herbal toothpaste. The significance of the Mann-Whitney test in the herbal and non-herbal toothpaste group was 0.037 (<0.05), which meant that there were differences in the effectiveness of herbal and non-herbal toothpaste in adolescent women. Conclusion: Toothpaste with herbal content was more effective in lowering plaque index in adolescent women compared to non-herbal toothpaste. Keywords: Adolescent, Herbal Toothpaste, Nonherbal Toothpaste, Plaque Index","PeriodicalId":31189,"journal":{"name":"Dentino Jurnal Kedokteran Gigi","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134903705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"TREATMENT OF GRANULOMATOUS EPULIS USING LASER","authors":"Novendy Yoyada, Dianty Saptaswari, Hansen Kurniawan, Onge Victoria Hendro","doi":"10.20527/dentino.v8i2.17538","DOIUrl":"https://doi.org/10.20527/dentino.v8i2.17538","url":null,"abstract":"Background: Epulis is an epithelial tumor that is non-osteogenic. Epulis can be found in the oral cavity both on the gingiva and in the alveolar mucosa. Epulis is a benign enlargement of soft tissue. Granulomatous epulis is one type of epulis that is often found. This granulomatous epulis is a granulative tissue reaction with the characteristics of bleeding easily and having a reddish color. This epulis can disturb the patient both psychologically because there is a large mass in the oral cavity, causing it to be unaesthetic if it occurs in the anterior teeth area, disrupting the chewing process and even disrupting the speech process if it is in the posterior teeth. Apart from causing discomfort to the patient, there are several types of epulis that can cause pain. Objective: To find out how to make a diagnosis of granulomatous epulis accompanied by treatment using a laser. Case: A 45 year old female patient came with complaints of enlarged gums since 1 year ago. The patient initially used dentures, but currently the dentures cannot be used and the patient feels uncomfortable because he cannot chew food due to a large lump in the oral cavity. Case Treatment: At the first visit, an etiotropic phase is carried out in the form of elimination of local factors, then the patient is referred for supporting examinations in the form of panoramic radiography and FNA-B examination. This examination functions to determine whether there is malignancy or not. After the results showed no malignancy, we continued with the surgical phase in the form of excision of granulomatous epulis using a laser. Conclusion: Granulomatous epulis therapy using laser accompanied by removal of remaining tooth roots shows satisfactory therapeutic results. Keyword: Epulis, Epulis Granulomatosa, Excision, Laser","PeriodicalId":31189,"journal":{"name":"Dentino Jurnal Kedokteran Gigi","volume":"75 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134903706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A RARE CLINICAL SYPHILIS ORAL MANIFESTATION DUE TO SEXUALLY TRANSMITTED DISEASE AMONG HOMOSEXUAL: CASE REPORT","authors":"Agustin Ninintowe T. Santo, Riani Setiadhi, Fika Faradillah Drakel","doi":"10.20527/dentino.v8i2.17529","DOIUrl":"https://doi.org/10.20527/dentino.v8i2.17529","url":null,"abstract":"Background: Syphilis is a sexually transmitted disease caused by Treponema pallidum, often found in Human Immunodeficiency Virus (HIV) patients and homosexuals. The oral manifestations are chancres, mucous patches, focal epithelial hyperplasia (FEH) and papilloma/condyloma. FEH is a rare oral mucosa disorder that occurs in immunocompromised patient. Objective: To present a rare oral manifestation in syphilis patient due to sexually transmitted infections. Case: A 25-year-old homosexual male came to Oral Medicine Department complaining of sores on the palate for 3 weeks and 2 weeks later a painless lump appeared. He was an HIV patient and had been taking ARVs since 6 months ago. Pain when opening the mouth, itching on his face and genital area. Intraoral revealed a soft, pedunculated, non-bleeding, mobile mass at the palate with a diameter about 2 cm, had the same color as the surrounding tissue. There was a reddish band-like area on the maxillary anterior gingival margin, suspected as Linear Gingival Erythema (LGE). Case management: 0.2% Chlorhexidine gluconate mouthwash was administered to prevent secondary infection and he was referred to Dermatovenereology and Periodontology Department. HBsAg Immunochromatography (negative), VDRL titer (reactive), TPHA titer (reactive) therefore diagnosis of syphilis was made and he was treated with a single dose Benzathine penicillin G 2.4 million units intramuscular. The oral lesions healed after 1 month therapy. Conclusion: FEH is a rare oral mucosa disorder in syphilis patients. Knowledge of the signs and symptoms of the disease is needed to make a diagnosis and a multidisciplinary approach to achieve successful treatment. Keywords: Oral manifestation, Sexual transmission, Syphilis, Treponemal infection","PeriodicalId":31189,"journal":{"name":"Dentino Jurnal Kedokteran Gigi","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134903539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"NECROTIZING ULCERATIVE GINGIVITIS AS A COMPLICATION OF FEBRILE NEUTROPENIA IN ACUTE MYELOID LEUKEMIA PATIENT","authors":"Desi Elvhira Rosa, Riani Setiadhi","doi":"10.20527/dentino.v8i2.17535","DOIUrl":"https://doi.org/10.20527/dentino.v8i2.17535","url":null,"abstract":"Background: Necrotizing ulcerative gingivitis (NUG) is a periodontal disease characterized by gingival pain, interdental gingival necrosis, and bleeding. NUG is closely related to immunosuppression, smoking, poor oral hygiene, malnutrition, and stress. Acute myeloid leukemia (AML) is a bone marrow malignant neoplasm. Chemotherapy as the treatment for AML often causes febrile neutropenia which results in immunosuppression conditions and is a risk factor for NUG. This case report aimed to discuss NUG as a complication of febrile neutropenia. Case: A 22-year-old woman was referred from hemato-oncology with acute myelomonocytic leukemia (AML-M4) and febrile neutropenia due to her oral complaints. She had undergone one cycle of chemotherapy and developed febrile neutropenia. Intra-oral showed ulcers covered with white-grayish plaques on the gingival region 35 to 45 and 15 to 25. There were white plaques that could be removed leaving an erythematous area on the dorsal tongue. Blood laboratory tests showed pancytopenia and severe neutropenia. The diagnoses were necrotizing ulcerative gingivitis and pseudomembranous candidiasis. Case management: Debridement using 1.5% hydrogen peroxide solution, rinsing with 0.2% chlorhexidine gluconate, as well as cleaning teeth and tongue 2 times daily. The internal medicine department gave meropenem. The lesions and gingiva were healed after three weeks of therapy. Conclusion: Febrile neutropenia due to chemotherapy reduces the body's ability to fight infection, oral homeostasis is disturbed therefore bacterial growth increases, neutrophils carry out phagocytosis forming reactive oxygen species which causing necrotic cells and then NUG occurred. Appropriate, adequate, and immediate therapy is needed to avoid further complications. Keywords: Acute myeloid leukemia, Febrile neutropenia, Necrotizing ulcerative gingivitis","PeriodicalId":31189,"journal":{"name":"Dentino Jurnal Kedokteran Gigi","volume":"75 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134903694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cover DENTINO VOL 8, NO 2 (2023)","authors":"Dentino FKG ULM","doi":"10.20527/dentino.v8i2.17542","DOIUrl":"https://doi.org/10.20527/dentino.v8i2.17542","url":null,"abstract":"","PeriodicalId":31189,"journal":{"name":"Dentino Jurnal Kedokteran Gigi","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135488324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ANTIBACTERIAL ACTIVITY TEST OF CALCIUM HYDROXIDE AND MAULI BANANA (Musa acuminata) STEM EXTRACT GEL MIXTURE AGAINST Enterococcus faecalis","authors":"Sukma Ayu Wardani, Dewi Puspitasari, Isyana Erlita","doi":"10.20527/dentino.v8i2.17598","DOIUrl":"https://doi.org/10.20527/dentino.v8i2.17598","url":null,"abstract":"Background: The use of calcium hydroxide as an intracanal medicament has several weaknesses that can cause side effects, including chronic inflammation in the periapical tissue and resistance to several bacteria, one of which is Enterococcus faecalis. The bacteria are the most resistant microorganism to calcium hydroxide due to a high pH tolerance capability. This weakness is the reason for finding alternative materials that can combine with calcium hydroxide. Mauli banana stem has bioactive compounds such as tannins, saponins, alkaloids, and flavonoids which have antibacterial and anti-inflammatory effects. Therefore, combined with calcium hydroxide may exhibit good characteristics as an intracanal medicament. Purpose: To analyze the antibacterial activity of the calcium hydroxide and mauli banana (Musa acuminata) stem extract gel mixture against Enterococcus faecalis. Methods: The research is a pure experimental study with a post-test only with control group design that uses 4 treatment groups, including calcium hydroxide and mauli banana stem extract gel mixture at a concentration of 25%; 37,5%; 50%; and control with each of 9 replications. The parameter measured was the diameter of the inhibition zone that formed on Mueller Hinton Agar. Result: One Way Anova and Bonferroni Post Hoc tests showed significant differences between each treatment group. Conclusion: The mixture of calcium hydroxide and mauli banana stem extract gel had antibacterial activity against Enterococcus faecalis. The mixture of calcium hydroxide and mauli banana stem extract gel at 50% concentration obtained the highest inhibition zone. Keywords: Antibacterial activity, Calcium hydroxide, Enterococcus faecalis, Musa acuminata","PeriodicalId":31189,"journal":{"name":"Dentino Jurnal Kedokteran Gigi","volume":"141 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135488321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}