Egyptian Rheumatology and Rehabilitation最新文献

{"title":"Standards for structured reporting of dual-energy X-ray absorptiometry scans: best practice recommendations by the Pan Arab Osteoporosis Society","authors":"Yasser El Miedany, Maha El Gaafary, Naglaa Gadallah, Riad Sulimani, Nadia S. AlAli, Ziad Alzoubi, Atef Abdel Azim, Nizar Abdulateef, Gemma Adib, Mohamed Elwy, Mustafa Khalid Al Izzi, Abdellah El Maghraoui, Safaa Mahran, Basel K. Masri, Samar Al Emadi, Mohammed Hassan Abu-Zaid, Elias Saba, Waleed Hassan, Manal El Rakaawi, Ali Otom, Walaa Elwakil","doi":"10.1186/s43166-023-00217-6","DOIUrl":"https://doi.org/10.1186/s43166-023-00217-6","url":null,"abstract":"Abstract Background Dual-energy X-ray absorptiometry (DXA) is an important diagnostic test for bone mass status. The aim of this work was to set the standards for structured reporting of DXA measurements in adults within the context of fracture and fall risk assessment. Results Two rounds of Delphi were completed. The first Delphi round had a 68% response rate, while round two had a 100% response rate. After round 2, a total of 28 items were obtained, which were classified into three domains. The percentage of people who agreed with the recommendations (ranks 9–7) ranged from 76.5 to 100%. The wording of all 19 clinical standards determined by the scientific committee was agreed upon (i.e., 75% of respondents strongly agreed or agreed). Conclusion The DXA scan report is an independent document that contains sufficient information to enable optimal osteoporosis management advised by an experienced healthcare professional. Setting up quality standards for DXA scans not only supports healthcare professionals reporting/interpreting bone densitometry but also meets the parameters outlined in national as well as international guidelines or recommendations for the optimal management of osteoporosis and subsequent prevention of low trauma fractures.","PeriodicalId":31002,"journal":{"name":"Egyptian Rheumatology and Rehabilitation","volume":"93 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135695563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of general public awareness, knowledge and attitude about common rheumatic diseases in Egypt: a multicenter study","authors":"Ola Eltabey Mahmoud Elsabae, Hisham Mohammed Habib, Wael Abdelmohsen Abady, Ahmed Roshdy Radwan, Reham Magdy Shaat, Ola Mohammad Gharbia","doi":"10.1186/s43166-023-00216-7","DOIUrl":"https://doi.org/10.1186/s43166-023-00216-7","url":null,"abstract":"Abstract Background Rheumatic diseases are the diseases of the connective tissue and medical disorders of the musculoskeletal system, with pain and/or stiffness as main manifestations, and which may or may not be accompanied by other organ system involvement. Public and patient’s awareness is needed as the number of patients of various forms of arthritis and other musculoskeletal diseases is constantly on rise. Objective The aim of our multicenter study is to evaluate awareness, knowledge, and attitude of general populations regarding common rheumatic diseases in Egypt. Subjects and methods This was a multicenter study included 3000 subjects from 4 Egyptian governorates (750 subjects from each): Lower Egypt: Dakahlia and Damietta and Upper Egypt: Sohag and Qena. Entire cases completed the Awareness, Knowledge, and Attitude of Egyptian people towards four of the common rheumatic diseases (Rheumatoid arthritis, Systemic lupus erythematosus, Crystal-induced arthritis, and Osteoarthritis): AKARSCO questionnaire that included basic information, general knowledge, and attitude about rheumatic diseases. Results The knowledge and awareness of rheumatic diseases are significantly higher among females. Regarding education level, there is a steady increase in the awareness with the rise of education level, with a highly significant correlation. Non-working and married participants had significantly higher knowledge compared to working and non-married ones. The attitude towards rheumatic diseases is significantly satisfactory among females. Regarding education level, there is a steady increase in the attitude with the rise of education level, with a highly significant correlation. Non-working and married participants had significant satisfactory attitude compared to working and non-married ones. The main sources of information about rheumatic diseases are media and Internet. Conclusion The overall awareness, knowledge, and attitude of population towards rheumatic diseases are limited in Egypt. The participants’ total score regarding the general knowledge level of rheumatic diseases, rheumatoid arthritis, SLE, gout, and osteoarthritis is bad. The participants’ overall level regarding the attitude towards rheumatic diseases is unsatisfactory. The level of knowledge and attitude is affected by many factors like sex, work, education, residence, marital status, and family history of rheumatic diseases. The main sources of information about rheumatic diseases are media and Internet.","PeriodicalId":31002,"journal":{"name":"Egyptian Rheumatology and Rehabilitation","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136343535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nailfold capillaroscopy in Egyptian systemic lupus erythematosus (SLE) patients: correlation with demographic features and serum levels of IL 17A and IFNs I","authors":"Mohamed Nasser, Mary Wadie, Alyaa Farid, Azza El Amir","doi":"10.1186/s43166-023-00215-8","DOIUrl":"https://doi.org/10.1186/s43166-023-00215-8","url":null,"abstract":"Abstract Background In SLE patients, cytokines are linked to endothelial cell damage. Nailfold capillaroscopy (NFC) is a simple method for evaluating micro-vascular abnormalities in different connective tissue diseases (CTDs). The study aimed to detect the levels of interleukin 17A (IL 17A), type I interferons (IFNs I) in the serum, and NFC changes in Egyptian SLE patients compared to a control group and to correlate NFC findings with patients’ demographic features and serum levels of IL 17A and IFNs I. Results Serum levels of IL 17A, IFN α, and IFN β were significantly higher in SLE patients than in control group ( P < 0.0001). About thirty nine patients (73.6%) of the 53 SLE patients showed abnormal NFC changes. Egyptian SLE patients had a high prevalence of the NFC non-specific pattern, with 32 (60.4%) patients showing non-specific changes and 7 (13.2%) patients showing scleroderma pattern, including 3 (5.6%) patients with active scleroderma pattern and 4 (7.55%) patients with late scleroderma pattern. Furthermore, Raynaud’s phenomenon (RP) was observed in 8 (15.1%) SLE patients, with 3 (5.6%) having normal NFC pattern and 5 (9.4%) having scleroderma pattern. All controls ( n = 20) showed normal hairpin shape capillaries. Except for SLEDAI ( P = 0.03) and the presence of RP ( P < 0.0001), there were no significant differences in demographic and laboratory parameters between the three NFC patterns (normal, non-specific, and scleroderma); additionally, NFC score correlated significantly with SLEDAI ( P = 0.021). Conclusion As a result of the high disease activity, Egyptian SLE patients had elevated serum levels of IL 17A and IFNs I. The most common NFC pattern in Egyptian SLE patients was a non-specific pattern. NFC abnormalities in Egyptian SLE patients were correlated with disease activity but not with patients’ ages, disease duration, or serum levels of IL 17A and IFNs I. SLE patients with scleroderma NFC pattern and RP should be closely followed for the possibility of appearance of anti-U1 RNP antibodies and MCTDS.","PeriodicalId":31002,"journal":{"name":"Egyptian Rheumatology and Rehabilitation","volume":"106 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135059865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Splinting in carpal tunnel syndrome—should we use it during the daytime?","authors":"Zeynep Kirac Unal, Ebru Umay, Ece Unlu Akyuz","doi":"10.1186/s43166-023-00214-9","DOIUrl":"https://doi.org/10.1186/s43166-023-00214-9","url":null,"abstract":"Abstract Background Splinting is frequently used in the treatment of CTS (carpal tunnel syndrome) and is mostly preferred at night. On the other hand, there are some studies suggesting the use of splint throughout the day. However, there is still no consensus. The aim of this randomized controlled study was to evaluate the effects of day and night splinting in terms of pain, symptom severity, functional status, and quality of life in patients with CTS. Results Seventy wrists of 46 patients with CTS were evaluated. In the day-night splint group, according to without splint group and night-only splint group, a statistically significant improvement was found in terms of pain level assessed by Visual Analogue Scale ( p = 0.001, p = 0.015, respectively), Boston Carpal Tunnel Questionnaire-Functional Severity Scale ( p = 0.004, p = 0.020, respectively), The Nottingham Health Profile-pain ( p = 0.001, p = 0.003, respectively), The Nottingham Health Profile-social isolation ( p = 0.001, p = 0.001, respectively), and The Nottingham Health Profile-total score ( p = 0.001, p = 0.012, respectively). In addition, it was found that even the use of splint only at night resulted in a significant reduction in pain compared to the control group ( p = 0.018). Conclusions Continuation of splinting as much as possible during the daytime in addition to night splinting is beneficial in terms of pain, nocturnal symptoms, functionality, and quality of life.","PeriodicalId":31002,"journal":{"name":"Egyptian Rheumatology and Rehabilitation","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135878151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biomarkers of sarcopenia: an unmet need","authors":"Mona El-Sebaie, Walaa Elwakil","doi":"10.1186/s43166-023-00213-w","DOIUrl":"https://doi.org/10.1186/s43166-023-00213-w","url":null,"abstract":"Abstract Background Sarcopenia is a syndrome characterized by a progressive decline in muscle mass and strength, with subsequent deterioration of functional performance and increased morbidity and mortality. Its emergence may be associated with disorders that are not limited to the elderly. The multifactorial nature of sarcopenia is a major barrier to diagnosis. Several risk factors contribute to the development of sarcopenia, including age, gender, and amount of physical activity. Additionally, the pathophysiology of sarcopenia involves inflammatory conditions, endocrinal dysfunction, and metabolic alterations. Several studies have proposed numerous molecules that may be linked to the pathogenesis of sarcopenia and could be useful in the future; however, there is an unmet need to discover a sensitive, reliable, and cost-effective biomarker of muscle aging. Main text The objective of this research is to highlight different biomarkers of sarcopenia that reflect its multifactorial pathophysiology. A narrative review was carried out through a series of literature searches in the database MEDLINE/PubMed focusing on sarcopenia biomarkers. The following search terms were used: “sarcopenia,” “osteosarcopenia,” “muscle ageing,” “muscle failure,” “sarcopenic obesity,” “weakness,” “biomarkers,” “frailty,” “comorbidity,” “functional disability,” and “inflamm-aging.” The studies were observational and peer-reviewed. They were all carried out at a referral center, hospital, or in the community. The articles chosen all contained information about sarcopenia. Case reports and articles that did not assess people's muscle aging and sarcopenia were not considered. Conclusion Despite the availability of numerous functional, imaging, and biological sarcopenia markers, the inherent limitations of the assessment tools make it difficult to objectively measure the various sarcopenia domains. A valid and reliable biomarker of sarcopenia has yet to be identified. The identification of “gold standard” evaluation techniques that should be systematically used is also impacted by the variability of the populations to be assessed. In this context, the establishment of an international consensus adopting a multi-biomarker approach may be of utmost importance to tackle the different aspects of this multifactorial health-related problem.","PeriodicalId":31002,"journal":{"name":"Egyptian Rheumatology and Rehabilitation","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135979424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fragmented QRS complex, highly sensitive CRP, and fibrinogen in early detection of asymptomatic cardiac involvement in systemic lupus erythematosus","authors":"Doaa E. Kamal, Dalia S. Fahmi, Noha A. Abdelsalam, Doaa M. Elsayed, Eman H. Seddik, Lobna I. Kotb","doi":"10.1186/s43166-023-00212-x","DOIUrl":"https://doi.org/10.1186/s43166-023-00212-x","url":null,"abstract":"","PeriodicalId":31002,"journal":{"name":"Egyptian Rheumatology and Rehabilitation","volume":" ","pages":""},"PeriodicalIF":0.8,"publicationDate":"2023-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46117812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Falls and fear of falling: an underestimated sequelae in Behçet’s disease","authors":"Doaa E. Kamal, Rofaida A. Hassan, Amany M. AbdAllah, Dalia I. Mostafa","doi":"10.1186/s43166-023-00211-y","DOIUrl":"https://doi.org/10.1186/s43166-023-00211-y","url":null,"abstract":"","PeriodicalId":31002,"journal":{"name":"Egyptian Rheumatology and Rehabilitation","volume":" ","pages":""},"PeriodicalIF":0.8,"publicationDate":"2023-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44779498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cultural adaptation and validation of the scleroderma health assessment questionnaire into Arabic language","authors":"Samah Mahmoud Alian, Enass Abdel-kader Eliwa, Sohair Atia Ahmed, Manar Ibrahim Abd El-Fattah Ibrahim","doi":"10.1186/s43166-023-00209-6","DOIUrl":"https://doi.org/10.1186/s43166-023-00209-6","url":null,"abstract":"Abstract Background Systemic sclerosis is an autoimmune multisystem disorder which affects the patients’ physical and psychological functioning. Scleroderma health assessment questionnaire used to measure physical disability in systemic sclerosis patients. It consists of Health Assessment Questionnaire Disability Index plus five visual analogue scores related to systemic sclerosis symptoms. There is no Arabic questionnaire specifically measuring physical disability in Arabic systemic sclerosis patients; therefore, this study aimed to translate the scleroderma health assessment questionnaire, culturally adapt it, and test its reliability and validity. Method The scleroderma health assessment questionnaire was translated into Arabic according to translation and cross-cultural adaptation guidelines. Convergent validity is measured by correlation of scleroderma health assessment questionnaire scores for 56 patients with short-form health survey scores, while discriminate validity is tested by stratifying clinical manifestations of patients and disease subtypes. Reliability measured by the intraclass correlation coefficient by interviewing patients twice 14 days apart. Results There was a strong correlation between the short-form health survey scores: physical component score and Health Assessment Questionnaire Disability Index and scleroderma health assessment questionnaire global scores ( r = − 0.659**, − 0.727**), while a moderate correlation between the short-form health survey scores physical component score, and scleroderma health assessment questionnaire, visual analogue scores, and all scleroderma health assessment questionnaire visual analogue score subtypes except for Raynaud’s and digital ulcer, was found ( r = − 0.495**, − 0.458*, − 0.495**, − 0.403*). The mental component score of the short-form health survey scores was moderately correlated with Health Assessment Questionnaire Disability Index and scleroderma health assessment questionnaire global scores ( r = − 0.507**, − 0.51**), while it was mildly correlated with scleroderma health assessment questionnaire visual analogue score and only its subtype overall severity score ( r = − 0.398*, − 0.375*). Also, statistically significant association is between diffuse disease type and digestive visual analogue score ( p = 0.001). The Arabic edition of scleroderma health assessment questionnaire has a Cronbach’s alpha of 0.845. Conclusion The translated Arabic version is a valid and reliable questionnaire to assess Egyptian systemic sclerosis patients’ functional disability.","PeriodicalId":31002,"journal":{"name":"Egyptian Rheumatology and Rehabilitation","volume":"66 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136279886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of chronic and neuropathic pain—journey mapping in Egypt","authors":"S. Khaled, N. Nasef, S. Arifeen, Mina Youssef, Sameh Nessim, M. Yazicioglu","doi":"10.1186/s43166-023-00200-1","DOIUrl":"https://doi.org/10.1186/s43166-023-00200-1","url":null,"abstract":"","PeriodicalId":31002,"journal":{"name":"Egyptian Rheumatology and Rehabilitation","volume":" ","pages":""},"PeriodicalIF":0.8,"publicationDate":"2023-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48401140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Consensus evidence-based recommendations for transition of care for adolescents with juvenile idiopathic arthritis: meeting patients’, parents’, and rheumatologists’ perspectives","authors":"Y. Miedany, M. H. Abu-Zaid, M. Eissa, W. Hassan, M. Mortada, S. Tabra, S. Mohamed, S. Maher, M. Gaafary, B. Medhat, D. M. Mosa, N. Fouad, Y. Amer, S. Nasef, Radwa H. Shalaby, Y. Adel, Reham Abd Elkhalek, M. Mahgoub, H. Lotfy","doi":"10.1186/s43166-023-00195-9","DOIUrl":"https://doi.org/10.1186/s43166-023-00195-9","url":null,"abstract":"","PeriodicalId":31002,"journal":{"name":"Egyptian Rheumatology and Rehabilitation","volume":" ","pages":""},"PeriodicalIF":0.8,"publicationDate":"2023-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45389020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}