Nida NotesPub Date : 1900-01-01DOI: 10.1151/V18I2ACMDMNTCC
S. Farrer
{"title":"Alternative Cigarettes May Deliver More Nicotine Than Conventional Cigarettes","authors":"S. Farrer","doi":"10.1151/V18I2ACMDMNTCC","DOIUrl":"https://doi.org/10.1151/V18I2ACMDMNTCC","url":null,"abstract":"","PeriodicalId":309693,"journal":{"name":"Nida Notes","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134465964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nida NotesPub Date : 1900-01-01DOI: 10.1151/V18I4TSLEMUIRAD
P. Zickler
{"title":"Twins Study Links Early Marijuana Use to Increased Risk of Abuse or Dependence","authors":"P. Zickler","doi":"10.1151/V18I4TSLEMUIRAD","DOIUrl":"https://doi.org/10.1151/V18I4TSLEMUIRAD","url":null,"abstract":"","PeriodicalId":309693,"journal":{"name":"Nida Notes","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130357810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nida NotesPub Date : 1900-01-01DOI: 10.1151/V17I6NMEBRSDA
P. Zickler
{"title":"Nicotine's Multiple Effects on the Brian's Reward System Drive Addiction","authors":"P. Zickler","doi":"10.1151/V17I6NMEBRSDA","DOIUrl":"https://doi.org/10.1151/V17I6NMEBRSDA","url":null,"abstract":"puzzle of what makes nicotine so addictive. Dr. Daniel McGehee and colleagues at the University of Chicago have shown that along with directly stimulating the brain’s reward system, nicotine also stimulates it indirectly by altering the balance of inputs from two types of neuron that help regulate its activity level. This additional stimulation intensifies the pleasure from smoking and makes it last longer. Scientists have long known that nicotine, like other addictive drugs, attaches to the core neurons of the brain’s reward system, where beneficial behaviors (such as drinking water when thirsty) are rewarded and reinforced. Situated in a region of the brain called the ventral tegmental area (VTA), these reward-system neurons, called dopaminergic neurons, trigger release of the neurotransmitter dopamine (DA) in a nearby brain region called the nucleus accumbens (NAc). When nicotine attaches to these neurons they increase their activity, flooding the NAc with dopamine, which produces pleasure and a disposition to repeat the behaviors that","PeriodicalId":309693,"journal":{"name":"Nida Notes","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121226317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nida NotesPub Date : 1900-01-01DOI: 10.1151/V18I3GVMINCSR
P. Zickler
{"title":"Genetic Variation May Increase Nicotine Craving and Smoking Relapse","authors":"P. Zickler","doi":"10.1151/V18I3GVMINCSR","DOIUrl":"https://doi.org/10.1151/V18I3GVMINCSR","url":null,"abstract":"help with a variety of treatments, including counseling, nicotine replacement therapy (patches, gum, lozenges, or inhalers), and medications. Some smokers use these treatments and succeed; for many, however, the discomfort of withdrawal and craving for nicotine lead to relapse. Recent NIDAfunded research suggests that our genes may partly explain this variable success. The research evaluated the effect of an enzyme, designated CYP2B6, on craving and relapse. This enzyme breaks down nicotine in the brain. Some people’s genes produce a more active form of the enzyme, while others have a less active form. Dr. Caryn Lerman at the NIDAand NCIsupported Transdisciplinary Tobacco Use Research Center (TTURC) at the University of Pennsylvania found that","PeriodicalId":309693,"journal":{"name":"Nida Notes","volume":"312 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115603424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nida NotesPub Date : 1900-01-01DOI: 10.1151/V18I1SAASEGDPD
Kimberly J. Martin
{"title":"Substance-Abusing Adolescents Show Ethnic and Gender Differences in Psychiatric Disorders","authors":"Kimberly J. Martin","doi":"10.1151/V18I1SAASEGDPD","DOIUrl":"https://doi.org/10.1151/V18I1SAASEGDPD","url":null,"abstract":"","PeriodicalId":309693,"journal":{"name":"Nida Notes","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122901947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nida NotesPub Date : 1900-01-01DOI: 10.1151/V17I4WSSFAAWPMCAKQ
Jill Williams
{"title":"Women and Smoking: Sensory Factors, Attitudes About Weight, Phase of Menstrual Cycle All Key To Quitting","authors":"Jill Williams","doi":"10.1151/V17I4WSSFAAWPMCAKQ","DOIUrl":"https://doi.org/10.1151/V17I4WSSFAAWPMCAKQ","url":null,"abstract":"","PeriodicalId":309693,"journal":{"name":"Nida Notes","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132049239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nida NotesPub Date : 1900-01-01DOI: 10.1151/V17I2HSIMFHIMWWID
R. Mathias
{"title":"High-Risk Sex Is Main Factor in HIV Infection for Men and Women Who Inject Drugs","authors":"R. Mathias","doi":"10.1151/V17I2HSIMFHIMWWID","DOIUrl":"https://doi.org/10.1151/V17I2HSIMFHIMWWID","url":null,"abstract":"","PeriodicalId":309693,"journal":{"name":"Nida Notes","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121678903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}