Bhavya Poojary, Merlin Maria Wilson, Riya Jose, Sona P Sam, Ann Elizabeth George, Mallikarjuna V Jeeragi
{"title":"Identifying Factors Associated With Cognitive Impairment in Thyroid Disorders and Prediction of Risk Using Machine Learning Approach: A Comprehensive Study","authors":"Bhavya Poojary, Merlin Maria Wilson, Riya Jose, Sona P Sam, Ann Elizabeth George, Mallikarjuna V Jeeragi","doi":"10.5505/amj.2023.89990","DOIUrl":"https://doi.org/10.5505/amj.2023.89990","url":null,"abstract":"Objectives: Thyroid disorders are a significant health concern in India and globally, being the second most common disease. Cognitive impairment associated with thyroid disorders is often neglected by healthcare providers, necessitating improved awareness and screening to identify neurocognitive changes in affected individuals. This study aimed to determine the prevalence of cognitive impairment in thyroid disorders and identify the associated risk factors. This study also predicted the risk of the development of cognitive impairment using a machine learning algorithm and was conducted in a tertiary hospital in South India. Materials and Methods: A prospective observational study was conducted among 202 patients with thyroid disorders over six months. In order to achieve primary and secondary goals, tools such as the M-ACE questionnaire and XGBoost algorithm were used. Data were collected using a validated form and analyzed using standard statistical methods. Results: Among the studied population, 29.21% were cognitively impaired, with an average M-ACE Score of 22.56± 2.62. Age, duration of illness, BMI, comorbidities, and tobacco chewing were sign ificant contributors when factors were analyzed for their association with cognitive impairment. A similar number of people with hypothyroidism and hyperthyroidism had a >75% risk of developing cognitive impairment in the near future. Conclusion: This study revealed that thyroid disorders have significant effects on the cognitive status of individuals and were also successful in predicting future risk.","PeriodicalId":30639,"journal":{"name":"Ankara Medical Journal","volume":"160 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135841631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Confronting the Dual Challenge: The Impact of the Covid-19 Pandemic on the Management of Acute Coronary Syndromes in a Leading Tertiary Hospital in Turkey","authors":"Esma Cetinkaya, H. Kundi, A. Aslan, M. Akçay","doi":"10.5505/amj.2023.25665","DOIUrl":"https://doi.org/10.5505/amj.2023.25665","url":null,"abstract":"","PeriodicalId":30639,"journal":{"name":"Ankara Medical Journal","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77118249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"From Trauma to Post-Traumatic Stress Disorder: Identification of the Risk Factors","authors":"Esra Kabadayi Sahin, F. Sevil","doi":"10.5505/amj.2023.90699","DOIUrl":"https://doi.org/10.5505/amj.2023.90699","url":null,"abstract":"","PeriodicalId":30639,"journal":{"name":"Ankara Medical Journal","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89297928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Are Pituitary Functions Different in Obese Patients According to Body Mass Index Classes?","authors":"N. Seyrek","doi":"10.5505/amj.2023.26096","DOIUrl":"https://doi.org/10.5505/amj.2023.26096","url":null,"abstract":"","PeriodicalId":30639,"journal":{"name":"Ankara Medical Journal","volume":"480 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77772174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Effects of VDR Gene Polymorphisms and Lifestyle Features on Vitamin D Levels of Post Menopausal Women","authors":"Meryem Çakır, Esra Meltem Koç, Mustafa Soyöz, Hatice İlayhan Karahan Çöven, Serpil Aydogmus, Kaan Sozmen","doi":"10.5505/amj.2023.03604","DOIUrl":"https://doi.org/10.5505/amj.2023.03604","url":null,"abstract":"Objectives: Vitamin D deficiency is a common situation for women who are in menopause due to various reasons. This study aims to investigate the effect of VDR gene polymorphisms and lifestyle on vitamin D levels of women in menopause. Materials and Methods: The study was planned in a cross-sectional descriptive design. Data was collected with a sociodemographic and lifestyle habits question form, and patients' blood samples were obtained for vitamin D levels and genetic tests. The data was evaluated by using SPSS 16.0 software. The logistic regression analysis model was created using the Backward elimination method, and the P-value below 0.05 was considered statistically significant. Results: The study was carried out on 303 menopausal women. The frequency of vitamin D deficiency in patients was 71.95%. Receiving vitamin D and Omega-3 supplements and having prolonged sleep duration were found to be protective factors from vitamin D deficiency. Of the VDR gene polymorphisms, the Bsml bb genotype was found to protect from vitamin D insufficiency, while the ApaI bb genotype increased the risk of vitamin D insufficiency. Conclusion: Vitamin D levels may be low in people who do not have sufficient sleep time. Our study found that the APA I aa genotype increased the risk of vitamin D deficiency, while the BsmI bb genotype protected from vitamin D deficiency. More studies are needed on the effects of lifestyle habits and genetic factors on serum vitamin D levels.","PeriodicalId":30639,"journal":{"name":"Ankara Medical Journal","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135840527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Do Healthcare Reforms Affect Health Status? Türkiye Practice","authors":"Hasan Bağcı","doi":"10.5505/amj.2023.45077","DOIUrl":"https://doi.org/10.5505/amj.2023.45077","url":null,"abstract":"Objectives: The aim of this study is to determine the impact of per capita health expenditure, the number of physicians, and the Health Transformation Program (HTP) implemented in Türkiye since 2003 on infant mortality. Materials and Methods: In this study, while the infant mortality rate per 1,000 live births (IM) was used as the dependent variable, the per capita health expenditure in US dollars according to purchasing power parity (HEX), the number of physicians per 1,000 population (PHY), and the HTP were used as independent variables. The Autoregressive Distributed Lag (ARDL) bounds testing approach was used in this study. Data covering the years of Türkiye from 1975 to 2018 were obtained from the OECD health statistics database for HEX and PHY, and from the World Bank database for IM. Results: According to the short and long term results of ARDL limit test, it was observed that the independent variables HEX, PHY and HTP reduced IM in the short term. However, it was found that the short-term results of independent variables HEX (p=0.157), PHY (p=0.390), and HTP (p=0.420) on IM were not statistically significant. According to the ARDL bounds test, the independent variables HEX, PHY, and HTP reduce IM in the long run. The long-term results of independent variables HEX (p=0.007), PHY (p=0.004) and HTP (p=0.012) on IM are statistically significant. Conclusion: The independent variables HEX, PHY and HTP were shown to reduce IM in the long term (p<0.05). It is recommended to monitor these identified effects and to develop public health policies accordingly.","PeriodicalId":30639,"journal":{"name":"Ankara Medical Journal","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135840526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association of reactive hypoglycemia with body mass index, homeostatic model assessment of insulin resistance and comorbidity","authors":"A. Mert, Ömer Faruk Tekin","doi":"10.5505/amj.2023.22844","DOIUrl":"https://doi.org/10.5505/amj.2023.22844","url":null,"abstract":"","PeriodicalId":30639,"journal":{"name":"Ankara Medical Journal","volume":"31 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72446072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Case Report of Acute Appendicitis Presenting with Diarrhea","authors":"Seyma Handan Akyon, R. Kipel, İ. Şencan","doi":"10.5505/amj.2023.77853","DOIUrl":"https://doi.org/10.5505/amj.2023.77853","url":null,"abstract":"","PeriodicalId":30639,"journal":{"name":"Ankara Medical Journal","volume":"146 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77633419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of medication adherence of individuals with chronic diseases during Ramadan","authors":"Tuğba Yılmaz","doi":"10.5505/amj.2023.70842","DOIUrl":"https://doi.org/10.5505/amj.2023.70842","url":null,"abstract":"","PeriodicalId":30639,"journal":{"name":"Ankara Medical Journal","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135840529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}