Biosaintifika Journal of Biology Biology Education最新文献_第7页

Carbon Stocks in the Conservation Area of PT. Pertamina (Persero) Fuel Terminal Boyolali 波约拉利Pertamina (Persero)燃料终端保护区碳储量

Biosaintifika Journal of Biology Biology Education Pub Date : 2022-07-28 DOI: 10.15294/biosaintifika.v14i2.35074

S. Sunarno, R. Rahadian, S. W. Suedy, Bayu Pradika, Bima Adistya

{"title":"Carbon Stocks in the Conservation Area of PT. Pertamina (Persero) Fuel Terminal Boyolali","authors":"S. Sunarno, R. Rahadian, S. W. Suedy, Bayu Pradika, Bima Adistya","doi":"10.15294/biosaintifika.v14i2.35074","DOIUrl":"https://doi.org/10.15294/biosaintifika.v14i2.35074","url":null,"abstract":"Flora biodiversity has been known to have a vital function in reducing carbon emissions in the air and contributing oxygen in significant levels to the environment. PT. Pertamina (Persero) Fuel Terminal Boyolali (FTB) has an important role in the conservation programs, protection of flora biodiversity, and environmental management. This study aims to analyze carbon stocks found in trees, plants cover soil, litter, necromas, and carbon in the soil and evaluate conservation of flora. This study uses a purposive random sampling method of carbon sources followed by the determination of carbon stocks in three conservation areas managed by PT. FTB, namely in the Wonopotro Forest, in the Pepe River watershed, and Pertamina's operational area. The samples from carbon sources include trees, litter, ground cover plants, necromas, and soil. The trees and necromas carbon sources sampling at each location was carried out at 2 stations with a size of 10 x 50 m2. Meanwhile, the sampling of litter, ground cover plants, and soil was carried out at 2 stations, each consisting of 3 plots. The results showed that the total carbon stock in the conservation areas was 1,688,0791 tons. The Pepe River watershed has the highest total carbon stock, which was 1,466,0928 tons/ha. The FTB and Wonopotro Forest, respectively, have about 180.7569 and 41.2294 tons/ha. The novelty of this research is the method of calculating carbon stocks in a conservation area that can be used as a database for assessing environmental management performance to the preservation of biological resources.","PeriodicalId":30622,"journal":{"name":"Biosaintifika Journal of Biology Biology Education","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86932609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Application Of Unmanned Aerial Vehicle (UAV) Remote Sensing Technology for Estimation of Tree Height in Heterogeneous Forest 无人机遥感技术在异质森林树高估算中的应用

Biosaintifika Journal of Biology Biology Education Pub Date : 2022-07-26 DOI: 10.15294/biosaintifika.v14i2.35637

Francine Hematang, Agustinus Murdjoko, H. Hendri, M. Tokede

{"title":"Application Of Unmanned Aerial Vehicle (UAV) Remote Sensing Technology for Estimation of Tree Height in Heterogeneous Forest","authors":"Francine Hematang, Agustinus Murdjoko, H. Hendri, M. Tokede","doi":"10.15294/biosaintifika.v14i2.35637","DOIUrl":"https://doi.org/10.15294/biosaintifika.v14i2.35637","url":null,"abstract":"Tree height is an important piece of information in forest management. Cost, time, and effort are some of the limiting factors in extracting tree height values on a large scale. The canopy height model approach through aerial photography using UAV can be used to quickly estimate the height of large-scale trees combined with field measurements. CHM analysis was carried out using spatial statistics to get the maximum tree height value based on the tree canopy. Evaluation of accuracy in the form of statistical tests is used to assess the level of accuracy of the estimation. Photogrammetry results show that the obtained CHM has a resolution of 11.8 cm/pixel with the results of the evaluation of tree height accuracy having an RMSE of 2.4 m, MAE 2.0 m, SDE 3.8 m. The chi-square statistical test shows that the results of the tree height estimation accept H0 and there is a strong relationship between the observed tree height and the estimation through linear regression with an R2 value of 0.67. The broad estimation of height shows that Mansinam Island has a tree height in the range of 7 – 66 m. The dominant tree height is in the 19-30 m class with the number of individuals reaching 1,877 trees. This study shows that CHM obtained from aerial photography using low-cost UAVs is still able to estimate tree height well. For future studies, it is necessary to use a ground control point (GCP) to increase the accuracy of the elevation model and orthophoto.","PeriodicalId":30622,"journal":{"name":"Biosaintifika Journal of Biology Biology Education","volume":"63 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90632791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Electroencephalogram Detection for Insomnia Patients: A Preliminary Study 失眠症患者脑电图检测的初步研究

Biosaintifika Journal of Biology Biology Education Pub Date : 2022-07-26 DOI: 10.15294/biosaintifika.v14i2.36255

Inosensia Lionetta Pricillia, Ahmad Azhari

{"title":"Electroencephalogram Detection for Insomnia Patients: A Preliminary Study","authors":"Inosensia Lionetta Pricillia, Ahmad Azhari","doi":"10.15294/biosaintifika.v14i2.36255","DOIUrl":"https://doi.org/10.15294/biosaintifika.v14i2.36255","url":null,"abstract":"Measurement of insomnia is currently generally carried out by medical practitioners by looking at the patient's condition accompanied by symptoms that refer to insomnia. In contrast, minimal quantitative measurements were found. This study proposes an alternative measurement with the acquisition of brainwave activity through electroencephalogram (EEG) in identifying sleep disorders. Insomnia is a common sleep disorder that can make it difficult to fall asleep difficult to stay asleep, or cause waking up too early and not being able to go back to sleep. Insomnia not only weakens energy levels and moods, but also a person's health, performance, and quality of life. This sleep disorder appears due to several factors, such as anxiety, stress, depression, bipolar disorder, or trauma. Photic stimulation is given as an attempt to find a person's body's response to light. Late adolescents with insomnia symptoms with an age range of 17-25 years were included as respondents, had previously been given a simulation test related to the treatment of sleep disorders, and identified severe, moderate, and mild insomnia. Acquisition using Narosky Mindwave Mobile 2 with the electrode in forehead position, Fp1. This study compares several types of insomnia data acquisition from previous studies and obtains patterns of insomniacs based on photic stimulation.","PeriodicalId":30622,"journal":{"name":"Biosaintifika Journal of Biology Biology Education","volume":"57 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89241912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Water Management Practices and Environmental Attitudes of Riparian Communities in Sapangdaku River, Cebu Island, Philippines 菲律宾宿务岛Sapangdaku河沿岸社区的水管理实践和环境态度

Biosaintifika Journal of Biology Biology Education Pub Date : 2022-07-26 DOI: 10.15294/biosaintifika.v14i2.36185

Joje Mar Perino Sanchez, Reginald Raymund A. Caturza, M. Picardal, Judelynn M. Librinca, Ruby L. Armada, Hedeliza Pineda, Marnan T. Libres, M. Paloma, Sherry P. Ramayla, J. Picardal

{"title":"Water Management Practices and Environmental Attitudes of Riparian Communities in Sapangdaku River, Cebu Island, Philippines","authors":"Joje Mar Perino Sanchez, Reginald Raymund A. Caturza, M. Picardal, Judelynn M. Librinca, Ruby L. Armada, Hedeliza Pineda, Marnan T. Libres, M. Paloma, Sherry P. Ramayla, J. Picardal","doi":"10.15294/biosaintifika.v14i2.36185","DOIUrl":"https://doi.org/10.15294/biosaintifika.v14i2.36185","url":null,"abstract":"Understanding the social-ecological dynamics of freshwater ecosystem is critical for effective planning and sustainable use of the resource. The study aimed to determine the socio-demographic profile, anthropogenic activities, water utilization of the residents, and waste disposal practices along the Sapangdaku River. Here, we examined water utilization, waste disposal practices and their corresponding impact to health, and environmental attitudes of riverside dwellers (n=120) in Sapangdaku River by using a standardized social health and environmental attitudes survey, respectively. Results show that while river water is still largely used for bathing and backyard farming, its known function as (a) disposal area of human and animal waste, (b) quarry site for pebbles and sand and (c) laundry area significantly decreased in recent years. Responses revealed that occurrence of very common ailments such as cough, gastroenteric problems and skin problems are partly associated to poor river water quality. In terms of people’s environmental attitude, ecocentrism is both positively correlated to environmental movement activism (r=0.445, p=0.000) and human utilization of nature (r=-0.275, p=0.006), putting prime value on the sustainable use of river water that provides benefit to the community. Similarly, environmental movement activism and human utilization of nature (r=-0.327, p=0.001) indicates willingness to participate in environmental activities, hence supported by their decision not to use their environment unfavorably. These findings suggest that community’s concern for the river water resulted to increased participation in various strategies to better maximize the use of the river for various purposes. However, efficient management and restoration of river quality require a holistic view of the problem.","PeriodicalId":30622,"journal":{"name":"Biosaintifika Journal of Biology Biology Education","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78034104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Liver Histopathology of Rats Induced by High-Fat Feed After Giving Neem Leaf Ethanol Extract 印楝叶乙醇提取物对高脂饲料大鼠肝脏组织病理学的影响

Biosaintifika Journal of Biology Biology Education Pub Date : 2022-07-26 DOI: 10.15294/biosaintifika.v14i2.34383

S. Isdadiyanto, Anggih Retno Pratiwi, S. M. Mardiati

{"title":"Liver Histopathology of Rats Induced by High-Fat Feed After Giving Neem Leaf Ethanol Extract","authors":"S. Isdadiyanto, Anggih Retno Pratiwi, S. M. Mardiati","doi":"10.15294/biosaintifika.v14i2.34383","DOIUrl":"https://doi.org/10.15294/biosaintifika.v14i2.34383","url":null,"abstract":"Foods that contain high levels of fat can cause hyperlipidemia, which is one of the triggering factors for non-alcoholic fatty liver disease. Neem leaves contain flavonoids, alkaloids and tannins which have the ability to act as hepatoprotectors. This study aimed to determine the Liver Histopathology of Rats Induced by High-Fat Feed After Giving Neem Leaf Ethanol Extract. Twenty-four the male white rats (Rattus norvegicus L.) were divided into 6 treatment groups, namely: normal control (P0); negative control (P1: given high-fat diet); P2 treatment (P1+ 8 mg/200gBW simvastatin); and P1+ the dose of neem leaf ethanolic extract of 75; 100; and 125 mg/200gBW (P3; P4; and P5). Fixation process with 10% Neutral Formalin Buffer (NFB) solution. Liver histopathological preparations were made by paraffin method and Hematoxylin-Eosin staining, histopathological observations with a 400x magnification microscope. Liver histopathology was analyzed descriptively, homogeneous and normally distributed data of liver weight and hepatocyte diameter were analyzed statistically using ANOVA followed by Duncan's test with a significance level of 5% using SPSS 16.0 software. The results showed that the administration of ethanolic extract of neem leaves could improve the liver histology structure. From this study it was concluded that the ethanolic extract of neem leaves can be used as an alternative hepatoprotector.","PeriodicalId":30622,"journal":{"name":"Biosaintifika Journal of Biology Biology Education","volume":"46 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83749748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Species Distribution and Antifungal Susceptibility of Candida spp. responsible for Pulmonary Candidiasis 肺念珠菌病念珠菌的种类分布及抗真菌敏感性

Biosaintifika Journal of Biology Biology Education Pub Date : 2021-12-10 DOI: 10.15294/biosaintifika.v13i3.31265

S. Suhartono, Wilda Mahdani, Rajuliana Rajuliana

{"title":"Species Distribution and Antifungal Susceptibility of Candida spp. responsible for Pulmonary Candidiasis","authors":"S. Suhartono, Wilda Mahdani, Rajuliana Rajuliana","doi":"10.15294/biosaintifika.v13i3.31265","DOIUrl":"https://doi.org/10.15294/biosaintifika.v13i3.31265","url":null,"abstract":"Fungal infection can occur in almost all parts of the human body, including the respiratory system. One group of fungi causing opportunistic infections in the lungs also known as pulmonary candidiasis is Candida spp. This study aimed to determine species diversity and antifungal sensitivity of Candida sp. causing pulmonary candidiasis from sputum specimen isolates in the Zainoel Abidin Hospital (ZAH). The sputum specimens were from inpatients and outpatients during a period of January 2019 to January 2021. Identification of Candida spp. and the antifungal sensitivity were carried out using culture and Gram Staining as well as the VITEK® 2 Compact. The results of this study indicated that there were six species of Candida sp. obtained from the study period. Of total 73 isolates, the highest percentage of species was Candida albicans (56.16%). The percentage of pulmonary candidiasis based on age was dominated by the early-late age category 46-65 years (50.68%) and based on sex was dominated by men (71.23%). Antifungal susceptibility assays revealed that the Candida species remained highly susceptible to the antifungals (amphotericin B, caspofungin, flucytosine, fluconazole, micafungin, and voriconazole), i.e., greater than 91 percent. Overall, the results of this study indicated that pulmonary candidiasis were predominantly related to C. albicans and C. tropicalis infections in ZAH and the sensitivity of antifungal drugs remained empirically and definitively effective. This research might be important as a part of infection prevention and control strategies, as well as the administration of empirical antifungals to combat Candida-mediated lung infections.","PeriodicalId":30622,"journal":{"name":"Biosaintifika Journal of Biology Biology Education","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75385880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diversity of Pathogenic Fungi and Disease on Vegetable Crops at Polyculture Systems 杂交种下蔬菜作物病原菌和病害的多样性

Biosaintifika Journal of Biology Biology Education Pub Date : 2021-08-27 DOI: 10.15294/biosaintifika.v13i2.26987

Eddy Tri Sucianto, Muachiroh Abbas

{"title":"Diversity of Pathogenic Fungi and Disease on Vegetable Crops at Polyculture Systems","authors":"Eddy Tri Sucianto, Muachiroh Abbas","doi":"10.15294/biosaintifika.v13i2.26987","DOIUrl":"https://doi.org/10.15294/biosaintifika.v13i2.26987","url":null,"abstract":"Vegetables polyculture system is potentially increasing pathogenic fungi diversity because various plant hosts are available. There is no data about patogenic fungi diversity at polyculture vegetable farming in Serang village, District of Karangreja, Purbalingga Regency. This study aimed to determine patogenic fungal diversity and disease percentage caused by the fungi at polyculture vegetable farming in Serang village, District of Karangreja, Purbalingga Regency. This research used purposive random sampling. Infected plants were collected at ten polyculture farming locations and fungal identification was performed at the laboratory. Fungi were identified morphologically based on the signs, symptoms, as well as macroscopic and microscopic characters. The fungi's pathogenity was determined by applying Koch's postulate test. The data were analyzed descriptively through literature comparison. The results showed that seven fungal species were found at polyculture farms in Serang Village. The obtained fungi were Colletotrichum sp., Fusarium sp., Alternaria sp., Septoria sp., Cercospora sp., Botryodiplodia sp., and Nigrospora sp. The lowest damage was 18.24% on tomato fruit infected by Fusarium sp. and the highest was on chili plants which was caused by Colletotrichum sp. The data is the first report for polycuture system. The obtained data has important implication for the management of vegetables farming in Serang Village.","PeriodicalId":30622,"journal":{"name":"Biosaintifika Journal of Biology Biology Education","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45523850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Conservation Status of Agarwood-Producing Species (Gyrinops versteegii) in Indonesia 印尼琼脂生产种（Gyrinops versteegii）的保护现状

Biosaintifika Journal of Biology Biology Education Pub Date : 2021-08-27 DOI: 10.15294/biosaintifika.v13i2.27809

S. Sutomo, R. Iryadi, I. Sumerta

{"title":"Conservation Status of Agarwood-Producing Species (Gyrinops versteegii) in Indonesia","authors":"S. Sutomo, R. Iryadi, I. Sumerta","doi":"10.15294/biosaintifika.v13i2.27809","DOIUrl":"https://doi.org/10.15294/biosaintifika.v13i2.27809","url":null,"abstract":"Aquilaria malaccensis and Gyrinops versteegii are agarwood producing plant species that is widely used because of its fragrance. Gyrinops versteegii has not been much cultivated and along with the decreasing population of G. versteegii in its natural habitat. This study aimed to assess scarcity status of Gyrinops versteegii based on distribution records from both herbarium and field exploration to assist the formulation of its conservation policy. Distribution data were obtained from online database and also from field exploration in Lombok, Sumbawa, and Flores Islands to obtain the population information. Area of Occupancy (AOO) and Extent of Occurrence (EOO) were calculated using GeoCAT (Geospatial Conservation Assessment Tool) and IUCN status recommendation was discussed. The estimated EOO was 868,422,919 km2, exceeding the value required for the threatened category. Based on EOO, it is included in the Least Concern (LC) category, but the EOO covers a large area of the ocean so the AOO was 116 km2 as meets criterion B (AOO<500 km2). It can be categorized into endangered (EN). Population data and conservation status of G verstegii are very important to provide recommendations on the quota wild-harvesting of agarwood by stakeholders.","PeriodicalId":30622,"journal":{"name":"Biosaintifika Journal of Biology Biology Education","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44184548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of Light Environments on Leaf Traits and Phenotypic Plasticity of Canna indica 光环境对美人蕉叶片性状及表型可塑性的影响

Biosaintifika Journal of Biology Biology Education Pub Date : 2021-08-27 DOI: 10.15294/biosaintifika.v13i2.30175

Y. Sasaerila, S. Sakinah, N. Noriko, R. S. Wijihastuti

{"title":"Effects of Light Environments on Leaf Traits and Phenotypic Plasticity of Canna indica","authors":"Y. Sasaerila, S. Sakinah, N. Noriko, R. S. Wijihastuti","doi":"10.15294/biosaintifika.v13i2.30175","DOIUrl":"https://doi.org/10.15294/biosaintifika.v13i2.30175","url":null,"abstract":"Canna indica L (African arrowroot), is a beneficial, multi-use tropical perennial with a worldwide distribution, but relatively unexplored. This plant has the potential to be developed as a food crop in an intercropping system, utilizing idle land under commercial plantations such as rubber or teak. This study aimed to determine the best light-growing conditions for C. indica. A completely randomized design was used with growth light as the treatment consisting of 25%, 50%, and 100% of natural light, respectively. Leaf traits, growth characteristics, and phenotypic plasticity were used to measure C. indica’s response to different treatments. The results of this study showed that C. indica grown in low light has the best growth with increased height, leaf area, root and shoot dry weights, but decreased leaf thickness, which caused the increase in specific leaf area, leaf area ratio, and leaf weight ratio, but decreased root to shoot ratio. Based on leaf traits and biomass allocation, the phenotypic plasticity index was 0.23, a typical number for shade tolerant species. These findings were the first time to be reported for C. indica. For agroforestry practices, it can be recommended that C. indica be used as an intercropping plant under tree canopies.","PeriodicalId":30622,"journal":{"name":"Biosaintifika Journal of Biology Biology Education","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44439084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

The Histomorphometry of Liver and Kidney of Hyperglycemic Albino Rats after Treatment with Tithonia diversifolia Leaf Extract 山楂叶提取物对高血糖白化大鼠肝、肾组织形态学的影响

Biosaintifika Journal of Biology Biology Education Pub Date : 2021-08-25 DOI: 10.15294/biosaintifika.v13i2.29459

R. F. Yuneldi, T. R. Saraswati, E. Y. W. Yuniwarti

{"title":"The Histomorphometry of Liver and Kidney of Hyperglycemic Albino Rats after Treatment with Tithonia diversifolia Leaf Extract","authors":"R. F. Yuneldi, T. R. Saraswati, E. Y. W. Yuniwarti","doi":"10.15294/biosaintifika.v13i2.29459","DOIUrl":"https://doi.org/10.15294/biosaintifika.v13i2.29459","url":null,"abstract":"Tithonia diversifolia can be used as an antidiabetic, so it is necessary to study the safety of its use, especially the side effects on the liver and kidneys. This study aimed to determine the effect of using T. diversifolia leaf extract through histomorphometry observations of the liver and kidneys of hyperglycemic albino rats. The study design used a completely randomized design (CRD). This study used 20 male albino rats which were divided into five treatment groups, there were T0 (rat normal/control), T1 (hyperglycemic rat without T. diversifolia leaf extract), T2 (hyperglycemic rat administered with Glibenclamide 10 mg/kg BW), T3 (hyperglycemic rat administered with T. diversifolia leaf extract 150 mg/kg BW), T4 (hyperglycemic rat administered with T. diversifolia leaf extract 300 mg/kg BW). Every treatment was repeated four times. The damage of hepatocyte and the glomerular cell was observed through histological structure observation by histomorphometry method using a photomicrography microscope (Olympus BX51). The results indicate that there were significant differences (P < 0.05) in the variable of hepatocytes diameter and there was no significant different (P > 0.05) result on glomerular diameter, as well as kidney and liver weight. It was concluded that T. diversifolia leaf extract of 150 mg/kg BW and 300 mg/kg BW are safe to be used as antidiabetic. It does not cause any side effects on the liver and kidneys of hyperglycemic albino rats. Thereby T. diversifolia leaf extract can be further tested as preparation of biopharmaca which can be used as herbal medicines for diabetics.","PeriodicalId":30622,"journal":{"name":"Biosaintifika Journal of Biology Biology Education","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46566565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2