Saude Tecnologia最新文献

{"title":"Estudo de caso de malformação congénita, com quantificação do êmbolo em 4 sistemas de suspensão para próteses endosqueléticas transtibiais com encaixe TSB","authors":"J. Matos, Mário Briôa, Gilda Cunha, Margarida Eiras, Margarida Ribeiro","doi":"10.25758/SET.1184","DOIUrl":"https://doi.org/10.25758/SET.1184","url":null,"abstract":"Introduction – The piston effect is one of the main problems regarding the effectiveness of prosthesis. A decrease of the piston effect can lead to a more natural gait by increasing proprioceptivity. Objectives – Check if there is a difference in piston effect values among various suspension systems for transtibial prosthesis with the use of Liners, and test the application of imaging tests in the analysis of the better prosthetic solution for a particular individual. Methods – Radiography of the prosthesis, in charge, in the orthostatic position, keeping the weight of the amputee equally distributed on bothfeet. Then was held another x-ray in the saggittal plane with the knee flexed at 30° with a weight of 5kg applied at the distal end of the prosthesis during 30sec. After these two exams the measurements for each type of suspension system was taken. Results – Of the four studied systems only three have piston values since one of the systems did not create enough suspension to withstand the weight placed on the distal end of the prosthesis. Through the radiology exams performed, measurements of the three systems could find piston effect variations ranging from 47.91mm to 72.55mm. Conclusion – By performing the imaging study there were differences at the level of the piston effect in the various suspension systems, proving that this is a viable tool in the evaluation of the piston effect. Also through the analysis of the results was notorious that the suspension system Vacuum Assisted Suspention System (VASS) is what presents less piston effect.","PeriodicalId":30555,"journal":{"name":"Saude Tecnologia","volume":"1 1","pages":"27-33"},"PeriodicalIF":0.0,"publicationDate":"2015-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69245868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Ressonância Magnética em Portugal","authors":"M. M. Ribeiro, Luís Freire","doi":"10.25758/SET.1004","DOIUrl":"https://doi.org/10.25758/SET.1004","url":null,"abstract":"A utilizacao generalizada da Imagem por Ressonância Magnetica (RM) em ambiente clinico comecou a partir da 2a metade dos anos 80 e, em relacao aos metodos de imagem, nomeadamente os que utilizam Radiacao X (Rx), ofereceu uma notavel combinacao entre seguranca, devido a ausencia de radiacoes ionizantes, resolucao espacial e de contraste e uma multifacetada sensibilidade e especificidade.","PeriodicalId":30555,"journal":{"name":"Saude Tecnologia","volume":"1 1","pages":"3"},"PeriodicalIF":0.0,"publicationDate":"2015-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69246128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"VI Encontro Nacional das Ciências e Tecnologias da Saúde","authors":"E. Lisboa","doi":"10.25758/SET.694","DOIUrl":"https://doi.org/10.25758/SET.694","url":null,"abstract":"Este numero especial da Saude & Tecnologia e dedicado ao VI Encontro Nacional de Ciencias e Tecnologias da Saude, realizado entre 20 e 23 de Outubro de 2011, na Escola Superior de Tecnologia da Saude de Lisboa. Trata-se de um Encontro de indiscutivel valor cientifico e muito participado, a avaliar pelas cinco edicoes anteriores, realizadas desde 1993, que tem contado sempre com a presenca de cientistas prestigiados e de um numero elevado de participantes. O contexto actual que atravessa o campo da saude desafia-nos a reelaboracao das reflexoes e a redefinicao das agendas cientificas e de intervencao profissional, acompanhando as dinâmicas emergentes que envolvem este sector. E neste quadro que se insere o programa do Encontro, estruturado em torno dos cinco eixos – Investigacao, Inovacao, Praticas, Cidadania e Internacionalizacao – presentes nas comunicacoes e nos debates previstos para as diferentes conferencias, paineis, sessoes tematicas simultâneas, cursos, workshops e simposios. A revista Saude & Tecnologia nao podia, pois, deixar de se associar a este evento de referencia impar no campo das ciencias e tecnologias da saude, atraves da publicacao do programa e dos resumos das comunicacoes livres e dos posters.","PeriodicalId":30555,"journal":{"name":"Saude Tecnologia","volume":"1 1","pages":"1-86"},"PeriodicalIF":0.0,"publicationDate":"2015-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69250003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sondas moleculares para a deteção de placas β-amilóide na doença de Alzheimer","authors":"L. Quental, Goreti Ribeiro Morais, I. Santos, Antônio Paulo","doi":"10.25758/SET.634","DOIUrl":"https://doi.org/10.25758/SET.634","url":null,"abstract":"The formation of amyloid structures is a neuropathological feature that characterizes several neurodegenerative disorders, such as Alzheimer´s and Parkinson´s disease. Up to now, the definitive diagnosis of these diseases can only be accomplished by immunostaining of post mortem brain tissues with dyes such Thioflavin T and congo red. Aiming at early in vivo diagnosis of Alzheimer´s disease (AD), several amyloid-avid radioprobes have been developed for b-amyloid imaging by positron emission tomography (PET) and single-photon emission computed tomography (SPECT). The aim of this paper is to present a perspective of the available amyloid imaging agents, special those that have been selected for clinical trials and are at the different stages of the US Food and Drugs Administration (FDA) approval.","PeriodicalId":30555,"journal":{"name":"Saude Tecnologia","volume":"1 1","pages":"5-9"},"PeriodicalIF":0.0,"publicationDate":"2015-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69250044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Estudo comparativo de procedimentos experimentais e computacionais para cálculo da lipofilia molecular","authors":"G. Clemente","doi":"10.25758/SET.344","DOIUrl":"https://doi.org/10.25758/SET.344","url":null,"abstract":"Comparative study of experimental and computational procedures for the calculation of molecular lipophilicity RESUMO: Introducao – A lipofilia e uma das propriedades fisico-quimicas que mais influencia a capacidade de uma molecula se movimentar atraves de compartimentos biologicos. O coeficiente de particao octanol/agua (log P ) permite, assim, obter uma estimativa da absorcao dos farmacos no organismo. A existencia de metodos indirectos para um calculo rapido do log P pode revelar-se de grande importância na analise de listas de compostos com potencial accao farmacologica, reduzindo-as aqueles que se preveem ter um melhor comportamento biologico. Objectivos – O proposito deste estudo e dar a conhecer um metodo cromatografico de RP-HPLC desenvolvido para a determinacao indirecta da lipofilia molecular e avaliar a performance de varios programas de calculo computacional desse mesmo parâmetro. Metodologias – Seleccionaram-se 25 compostos quimicos, avaliou-se o log P de cada um deles por RP-HPLC e confrontaram-se os resultados obtidos com os de sete programas computacionais. Resultados – O metodo RP-HPLC testado demonstrou ser vantajoso em comparacao com o convencional shake flask. O programa de calculo indirecto que proporcionou resultados mais proximos dos experimentais foi o ALOGPS© 2.1. Conclusoes – A escolha ideal para a determinacao da lipofilia de compostos cujo log P estimado esteja entre 0 e 6 e, sobretudo no que diz respeito a rapidez e simplicidade do processo, o metodo experimental indirecto RP-HPLC. Quanto aos metodos computacionais concluiu-se que nenhum dos programas, incluindo o ALOGPS© 2.1, demonstrou ser eficaz na avaliacao de isomeros pelo que, para estes compostos, sera sempre necessario recorrer ao metodo shake flask ou RP-HPLC. Palavras-chave: lipofilia, log P, RP-HPLC, calculo computacional","PeriodicalId":30555,"journal":{"name":"Saude Tecnologia","volume":"1 1","pages":"29-34"},"PeriodicalIF":0.0,"publicationDate":"2015-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69247667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Análise da acuidade visual no implante de LIO fáquica em miopias elevadas","authors":"V. Santos, I. Poças, Carina Silva, N. Alves, A. Cardoso","doi":"10.25758/SET.1224","DOIUrl":"https://doi.org/10.25758/SET.1224","url":null,"abstract":"Introduction – Intraocular phakic lens implantation surgery has been progressively preferred to laser surgery in the treatment of high myopia. Visual acuity (AV) pre and post refractive implant surgery has been compared, showing that this method is more effective in the improvement of the vision in high myopia. Methods – Seventy eyes belonging to 41 patients with high myopia were analyzed retrospectively. The age of the patients ranged from 20 to 50 years and they all had refractive implant surgery between 2009 and 2012. Results – One day post surgery, 42.86% of the sample had an improvement in visual acuity, 34.29% remained unchanged and 22.85% worsened. A generalized increase in the quality of vision was observed after 30 days. 64.29% scored 10/10 in visual acuity, 24.29% scored between 7/10 and 9/10, and 11.42% between 4/10 and 6/10. Conclusion – The effectiveness of this surgical technique was proved, showing an improvement in visual acuity in 52.86% of the sample","PeriodicalId":30555,"journal":{"name":"Saude Tecnologia","volume":"1 1","pages":"11-15"},"PeriodicalIF":0.0,"publicationDate":"2015-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69246200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A farmacogenética e a medicina personalizada","authors":"M. Brito","doi":"10.25758/SET.1214","DOIUrl":"https://doi.org/10.25758/SET.1214","url":null,"abstract":"Pharmacogenetics aims to identify genetic differences between individuals that may influence the response to drug therapy, improving their effectiveness and safety. Associated with the pharmacogenetics emerges ‘personalized medicine’. In opposition to the existence of a drug that can treat all patients, the individualized treatment seems the most promising as it reduces the risk of side effects for toxicity (safety), reduces losses due to excess or deficit (dose), avoiding the testing methodology in the choice of the correct drug (effectiveness). Pharmacogenetics is relevant to the individual response to the drug in two ways: the pharmacokinetics and pharmacodynamics. The genetic variability can affect the way a drug can be absorbed, metabolized, excreted or activated, and can drive to a difference in the patient response. Among the endless number of possible examples, in this review we present examples related to cytochrome P450 genes, NAT2 gene and the Cholinesterase gene. Genetic differences between individuals can still affect the response to the drug by its pharmacodynamics, drug target-specific response to a particular drug. Among the multitude of existing drug targets, it will be presented examples of the G6PD gene, and the VKORC1 gene. Despite some evidence given for the benefit of the patient, we are still far from Pharmacogenetics to be part of routine clinical practice, perhaps because the cost-benefit have not yet been correctly assessed.","PeriodicalId":30555,"journal":{"name":"Saude Tecnologia","volume":"1 1","pages":"5-10"},"PeriodicalIF":0.0,"publicationDate":"2015-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69246612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influência da experiência profissional e da função visual do operador no processamento semiautomático da cintigrafia de perfusão do miocárdio: variabilidade intra e interoperador na determinação dos parâmetros quantitativos","authors":"Ana Sofia Reimão, Joana Pereira, Matina Nobre, Fábio Nascimento, E. Carolino, I. Poças, L. Vieira","doi":"10.25758/SET.1234","DOIUrl":"https://doi.org/10.25758/SET.1234","url":null,"abstract":"Introduction – Myocardial perfusion scan (MPS) has an important role in the diagnosis, evaluation and follow-up of patients with coronary artery disease being the semiautomatic processing widely used for routine clinical practice. Since the nuclear medicine technologists (NMT) performance might be affected by individual and environmental factors, different professionals that process the same data will provide different estimations of quantitative parameters (QP). Aim – Evaluate the influence of NMT professional experience and visual function on the MPS semiautomatic processing. Analysis of the intra and inter variability considering the function and perfusion QP measured. Methodology – Twenty subjects were selected and categorized in two groups according to their experience on the Quantitative Gated SPECTTM software: Group A (GA) – NMT ≥600h and Group B (GB) – NMT without experience. All NMT underwent an orthoptic evaluation and processed 21 MPS five times in a non-consecutive mode. It was assumed to be an altered vision when at least one visual function parameter was found abnormal. Coefficient of variation, %, was calculated to evaluate repeatability and reproducibility. Friedman’s and Wilcoxon tests were applied to compare QP between operators and to analyze GA and GB performance, respectively, considering the processing of the same MPS. To compare the NMT with normal and altered vision it was used the Mann-Whitney Test, and to evaluate the visual function influence in each QP was performed the ETA association coefficient. It was assumed statistically significant differences at a significance level of 5%. Results and Discussion – Low intra (<6.59%) and inter (<5.07%) operator variability was achieved. A greater discrepancy in GB was noted, being merely the septal wall (SW) statistical different (zw=-2.051, p=0.040), when compared with GA. Regarding the influence of visual function it was observed significant statistical differences only in left ventricle ejection fraction (LVEF) (U=11.5, p=0.012) between NMT with normal and altered vision, contributing the vision 33.99% for its variation. It was denoted more differences between NMT that have a greater incidence of ocular symptomology and a diminished Binocular Vision. LVEF was the most consistent QP (1.86%) between operators. Conclusion – MPS is presented as a repeatable and reproducible technique, operator independent. It was verified professional experience and visual function influence, on MPS semiautomatic processing, in the SW and LVEF QP, respectively","PeriodicalId":30555,"journal":{"name":"Saude Tecnologia","volume":"1 1","pages":"16-25"},"PeriodicalIF":0.0,"publicationDate":"2015-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69246247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treino de músculos inspiratórios em indivíduos saudáveis: estudo randomizado controlado","authors":"Fábio Esteves, Inês Santos, João Valeriano, M. Tomás","doi":"10.25758/SET.1331","DOIUrl":"https://doi.org/10.25758/SET.1331","url":null,"abstract":"Introduction – The inspiratory muscle training (IMT) emerges as an important intervention in people with COPD, but above all with a growing interest in the healthy population. However, there are not enough studies to prove if the inspiratory muscle training is also reflected in the improvement of the aerobic capacity objectified in oxygen consumption (VO 2 ). Therefore more investigation is relevant to understand the real relationship between IMT and its results on healthy people. Thus, it was considered appropriate to carry out a research study on healthy population that would allow assessing to what extent an inspiratory muscle training program induces changes in inspiratory muscular strength and aerobic capacity. Methods and analysis – The sample was based on healthy individuals ( n =19) between 18 and 21 years old who perform regular physical exercise (≥ 3 times a week or ≥ 4 hours per week). The aerobic capacity was estimated by the Ebbeling Test and inspiratory muscle strength was measured by the maximum inspiratory pressure (MIP) obtained by a specific dynamometer (MicroRPM ® ) at two different times (pre and post-workout). The above mentioned sample was randomly divided into two groups ( n =9 in the experimental group and n =10 in the control group). The experimental group (EG) was subjected to a high intensity IMT (≥50% Pi, max) while the control group (CG) didn´t go through any intervention. The IMT was performed by PowerBreathe Classic ® Level 1 and Level 2 that provides a consistent and specific pressure for inspiratory muscle strength regardless of the individual's inspiratory flow. Conclusions – After the training, there was a 37% increase in EG PIM while the CG showed an improvement of 7%. In intergroup comparison, both groups increased significantly both as MIP and VO 2 ( p <0.05). However, comparing both groups, the differences were significant for the PIM ( p =0.000), but not to VO 2 . Further studies are required to assess in which conditions IMT produces changes in aerobic capacity.","PeriodicalId":30555,"journal":{"name":"Saude Tecnologia","volume":"1 1","pages":"5-11"},"PeriodicalIF":0.0,"publicationDate":"2015-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69246493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Novos rumos na educação e promoção da saúde a partir de uma reflexão sobre a intervenção com crianças e adolescentes no trabalho do Aventura Social","authors":"M. Matos","doi":"10.25758/SET.1094","DOIUrl":"https://doi.org/10.25758/SET.1094","url":null,"abstract":"Na ultima decada, a investigacao na area da saude deixou de se centrar apenas na compreensao das doencas e condicoes lesivas da saude para passar a interessar‑se pelos fatores determinantes destas condicoes de modo a passar a uma acao preventiva (antes de deixar que os problemas se instalem). Passou depois a interessar‑se nao so pelos problemas e seus determinantes, mas tambem pelos fatores e processos associados a promocao da propria saude, enquanto estado dinâmico de bem‑estar global.","PeriodicalId":30555,"journal":{"name":"Saude Tecnologia","volume":"1 1","pages":"5-7"},"PeriodicalIF":0.0,"publicationDate":"2014-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69246029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}