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TP8. TP008 OMICS STUDIES IN OBSTRUCTIVE AIRWAYS DISEASE最新文献

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Whole-Genome Sequencing Based Meta-Analysis of Asthma Exacerbations from the Asthma Translational Genomic Collaborative (ATGC) of the Trans-Omics for Precision Medicine (TOPMed) Program 来自反式精准医学组学(TOPMed)项目哮喘转化基因组协作(ATGC)的基于全基因组测序的哮喘加重meta分析
TP8. TP008 OMICS STUDIES IN OBSTRUCTIVE AIRWAYS DISEASE Pub Date : 1900-01-01 DOI: 10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1382
H. Gui, D. Hu, P. Sleiman, S. Xiao, M. Yang, S. Hochstadt, D. Dynkowski, D. Lanfear, A. Mak, F. Gilliland, W. Gauderman, R. Kumar, F. Martinez, D. Erle, H. Hakonarson, E. Burchard, L. Williams
{"title":"Whole-Genome Sequencing Based Meta-Analysis of Asthma Exacerbations from the Asthma Translational Genomic Collaborative (ATGC) of the Trans-Omics for Precision Medicine (TOPMed) Program","authors":"H. Gui, D. Hu, P. Sleiman, S. Xiao, M. Yang, S. Hochstadt, D. Dynkowski, D. Lanfear, A. Mak, F. Gilliland, W. Gauderman, R. Kumar, F. Martinez, D. Erle, H. Hakonarson, E. Burchard, L. Williams","doi":"10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1382","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1382","url":null,"abstract":"","PeriodicalId":304163,"journal":{"name":"TP8. TP008 OMICS STUDIES IN OBSTRUCTIVE AIRWAYS DISEASE","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131237793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sex-Specific Gene Expression in the Sputum of Patients with Asthma 哮喘患者痰液性别特异性基因表达的研究
TP8. TP008 OMICS STUDIES IN OBSTRUCTIVE AIRWAYS DISEASE Pub Date : 1900-01-01 DOI: 10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1383
S. Kay, G. Chupp, J. L. Gómez
{"title":"Sex-Specific Gene Expression in the Sputum of Patients with Asthma","authors":"S. Kay, G. Chupp, J. L. Gómez","doi":"10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1383","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1383","url":null,"abstract":"","PeriodicalId":304163,"journal":{"name":"TP8. TP008 OMICS STUDIES IN OBSTRUCTIVE AIRWAYS DISEASE","volume":"60 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134439959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Type-2 Endotypes in Severe Asthma Are Stable Over Time and Demonstrate Markedly Different Transcriptomic Responses to Corticosteroids 重度哮喘患者的2型内型随着时间的推移是稳定的，并且对皮质类固醇表现出明显不同的转录组反应
TP8. TP008 OMICS STUDIES IN OBSTRUCTIVE AIRWAYS DISEASE Pub Date : 1900-01-01 DOI: 10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1390
P. DeFord, J. Fahy, M. Castro, S. Erzurum, S. Comhair, A. Hastie, W. Moore, E. Bleecker, M. Johansson, L. Denlinger, B. Levy, E. Israel, D. Mauger, B. Phillips, S. Wenzel, M. Seibold, M. Peters, H.R.P. National Heart Lung and Blood Institute Severe Ast
{"title":"Type-2 Endotypes in Severe Asthma Are Stable Over Time and Demonstrate Markedly Different Transcriptomic Responses to Corticosteroids","authors":"P. DeFord, J. Fahy, M. Castro, S. Erzurum, S. Comhair, A. Hastie, W. Moore, E. Bleecker, M. Johansson, L. Denlinger, B. Levy, E. Israel, D. Mauger, B. Phillips, S. Wenzel, M. Seibold, M. Peters, H.R.P. National Heart Lung and Blood Institute Severe Ast","doi":"10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1390","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1390","url":null,"abstract":"","PeriodicalId":304163,"journal":{"name":"TP8. TP008 OMICS STUDIES IN OBSTRUCTIVE AIRWAYS DISEASE","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117304533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bronchial Allergen Challenge Induces IL-17A and Associated Gene Expression Changes Related to fMRI Activation in the Amygdala and Insula 支气管过敏原刺激诱导杏仁核和脑岛中与fMRI激活相关的IL-17A及其相关基因表达变化
TP8. TP008 OMICS STUDIES IN OBSTRUCTIVE AIRWAYS DISEASE Pub Date : 1900-01-01 DOI: 10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1389
M. Rosenkranz, K. Dill-McFarland, S. Esnault, N. Jarjour, W. Busse, M. Altman
{"title":"Bronchial Allergen Challenge Induces IL-17A and Associated Gene Expression Changes Related to fMRI Activation in the Amygdala and Insula","authors":"M. Rosenkranz, K. Dill-McFarland, S. Esnault, N. Jarjour, W. Busse, M. Altman","doi":"10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1389","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1389","url":null,"abstract":"","PeriodicalId":304163,"journal":{"name":"TP8. TP008 OMICS STUDIES IN OBSTRUCTIVE AIRWAYS DISEASE","volume":"101 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117251778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Metabolomic Analysis of Asthma Phenotypes across Multiple Cohorts 多队列哮喘表型的代谢组学分析
TP8. TP008 OMICS STUDIES IN OBSTRUCTIVE AIRWAYS DISEASE Pub Date : 1900-01-01 DOI: 10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1381
K. Mendez, M. Coté, M. Huang, R. Kelly, P. Kachroo, S. Chu, D. Soeteman, S. Reinke, C. Wheelock, J. Celedón, C. Clish, S. Weiss, J. Lasky-Su
{"title":"Metabolomic Analysis of Asthma Phenotypes across Multiple Cohorts","authors":"K. Mendez, M. Coté, M. Huang, R. Kelly, P. Kachroo, S. Chu, D. Soeteman, S. Reinke, C. Wheelock, J. Celedón, C. Clish, S. Weiss, J. Lasky-Su","doi":"10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1381","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1381","url":null,"abstract":"","PeriodicalId":304163,"journal":{"name":"TP8. TP008 OMICS STUDIES IN OBSTRUCTIVE AIRWAYS DISEASE","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125503119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Circular RNA Is Altered in COPD and Cigarette Smoking 环状RNA在COPD和吸烟中发生改变
TP8. TP008 OMICS STUDIES IN OBSTRUCTIVE AIRWAYS DISEASE Pub Date : 1900-01-01 DOI: 10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1392
A. Saferali, J. Yun, Z. Xu, S. Lee, R. Chase, P. Castaldi, C. Hersh
{"title":"Circular RNA Is Altered in COPD and Cigarette Smoking","authors":"A. Saferali, J. Yun, Z. Xu, S. Lee, R. Chase, P. Castaldi, C. Hersh","doi":"10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1392","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1392","url":null,"abstract":"","PeriodicalId":304163,"journal":{"name":"TP8. TP008 OMICS STUDIES IN OBSTRUCTIVE AIRWAYS DISEASE","volume":"47 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131838179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lower Airway Microbial Signatures in Early COPD 早期COPD的下气道微生物特征
TP8. TP008 OMICS STUDIES IN OBSTRUCTIVE AIRWAYS DISEASE Pub Date : 1900-01-01 DOI: 10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1391
M. Holub, Jun-Chieh J. Tsay, B. Wu, I. Sulaiman, R. Schluger, Y. Li, J. Carpenito, Sergei B Koralov, J. Clemente, L. Segal
{"title":"Lower Airway Microbial Signatures in Early COPD","authors":"M. Holub, Jun-Chieh J. Tsay, B. Wu, I. Sulaiman, R. Schluger, Y. Li, J. Carpenito, Sergei B Koralov, J. Clemente, L. Segal","doi":"10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1391","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1391","url":null,"abstract":"","PeriodicalId":304163,"journal":{"name":"TP8. TP008 OMICS STUDIES IN OBSTRUCTIVE AIRWAYS DISEASE","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122987762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Temporal Fluctuation of Systemic Markers in Urine During a Nasal Rhinovirus Challenge in Healthy and Asthmatic Subjects 健康和哮喘受试者鼻鼻病毒感染期间尿液系统标志物的时间波动
TP8. TP008 OMICS STUDIES IN OBSTRUCTIVE AIRWAYS DISEASE Pub Date : 1900-01-01 DOI: 10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1385
A. Sinha, C. Wheelock, X. Binbin, U. Frey, P. Sterk, R. Lutter, R. Chaleckis
{"title":"Temporal Fluctuation of Systemic Markers in Urine During a Nasal Rhinovirus Challenge in Healthy and Asthmatic Subjects","authors":"A. Sinha, C. Wheelock, X. Binbin, U. Frey, P. Sterk, R. Lutter, R. Chaleckis","doi":"10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1385","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1385","url":null,"abstract":"","PeriodicalId":304163,"journal":{"name":"TP8. TP008 OMICS STUDIES IN OBSTRUCTIVE AIRWAYS DISEASE","volume":"57 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128711921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Large-Scale Genome-Wide Association Analysis of Lung Function in Chinese and European Populations Identifies Novel Loci and Highlights Shared Genetic Etiology with Obesity 中国和欧洲人群肺功能的大规模全基因组关联分析发现了新的基因座，并强调了肥胖的共同遗传病因
TP8. TP008 OMICS STUDIES IN OBSTRUCTIVE AIRWAYS DISEASE Pub Date : 1900-01-01 DOI: 10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1394
Z. Zhu, J. Li, J. Si, H. Shi, J. Lv, W. Cao, Y. Guo, I. Millwood, R. Walters, K. Lin, L. Yang, Y. Chen, H. Du, B. Yu, K. Hasegawa, C. Camargo, M. Moffatt, W. Cookson, J. Chen, Z. Chen, L. Li, C. Yu, L. Liang
{"title":"A Large-Scale Genome-Wide Association Analysis of Lung Function in Chinese and European Populations Identifies Novel Loci and Highlights Shared Genetic Etiology with Obesity","authors":"Z. Zhu, J. Li, J. Si, H. Shi, J. Lv, W. Cao, Y. Guo, I. Millwood, R. Walters, K. Lin, L. Yang, Y. Chen, H. Du, B. Yu, K. Hasegawa, C. Camargo, M. Moffatt, W. Cookson, J. Chen, Z. Chen, L. Li, C. Yu, L. Liang","doi":"10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1394","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1394","url":null,"abstract":"","PeriodicalId":304163,"journal":{"name":"TP8. TP008 OMICS STUDIES IN OBSTRUCTIVE AIRWAYS DISEASE","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127247675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Integrated Analysis of the Lung Microbiome and Metabolome Reveals Bacterial and Metabolite Features Co-Associated with Clinical Outcomes in COPD 肺部微生物组和代谢组的综合分析揭示了与COPD临床结果相关的细菌和代谢物特征
TP8. TP008 OMICS STUDIES IN OBSTRUCTIVE AIRWAYS DISEASE Pub Date : 1900-01-01 DOI: 10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1393
Y.J. Huang, S. Madapoosi, C. Cruickshank-Quinn, K. Opron, J. Erb-Downward, L. Begley, V. Ortega, P. Woodruff, W.W. Labaki, J. Curtis, G. Huffnagle, K. Stringer, R. Bowler, C.R. Esther, N. Reisdorph, for SPIROMICS investigators
{"title":"Integrated Analysis of the Lung Microbiome and Metabolome Reveals Bacterial and Metabolite Features Co-Associated with Clinical Outcomes in COPD","authors":"Y.J. Huang, S. Madapoosi, C. Cruickshank-Quinn, K. Opron, J. Erb-Downward, L. Begley, V. Ortega, P. Woodruff, W.W. Labaki, J. Curtis, G. Huffnagle, K. Stringer, R. Bowler, C.R. Esther, N. Reisdorph, for SPIROMICS investigators","doi":"10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1393","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1393","url":null,"abstract":"","PeriodicalId":304163,"journal":{"name":"TP8. TP008 OMICS STUDIES IN OBSTRUCTIVE AIRWAYS DISEASE","volume":"56 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124646989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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