Nigerian Journal of Surgery最新文献

{"title":"Micronuclei in Exfoliated Cells: A Biomarker of Genotoxicity in Tobacco Users.","authors":"Meenakshi Upadhyay,&nbsp;Parul Verma,&nbsp;Robin Sabharwal,&nbsp;Santosh Kumar Subudhi,&nbsp;Suruchi Jatol-Tekade,&nbsp;Vihang Naphade,&nbsp;Basanta Kumar Choudhury,&nbsp;Pravudeva Devidutta Sahoo","doi":"10.4103/njs.NJS_10_18","DOIUrl":"https://doi.org/10.4103/njs.NJS_10_18","url":null,"abstract":"<p><strong>Aims: </strong>The aim of this study was to analyze the tobacco-related genotoxic effects in individual with habit of smoking and chewing tobacco.</p><p><strong>Materials and methods: </strong>The present study sample consisted of 120 individuals attending the outpatient department of D. J. College of Dental Sciences and Research, Modinagar, Uttar Pradesh (UP). The sample was divided into four groups as follows: Group I (individuals with habit of smoking tobacco), Group II (individuals with habit of chewing tobacco), Group III (individuals with habit of smoking and chewing tobacco), and Group IV control group (nontobacco-exposed individuals). Patients were asked to rinse their mouth gently with water. The exfoliated cells were obtained by scraping the buccal mucosa of individuals with a wooden spatula. The scraped cells were placed on the precleaned slides. The smears were then stained with RAPID-PAP™ and analyzed under the microscope. Data were analyzed using SPSS statistical software.</p><p><strong>Results: </strong>In the present study, an arbitrary unit was obtained using frequency/day multiplied by the duration of years (risk multiplication factor [RMF], a positive and significant correlation were observed between the RMF and the mean percentage of micronucleated cell count in smokers, chewers, and in individuals with both smoking and chewing habit, respectively. A weak positive and nonsignificant correlation were observed between age and mean percentage of micronucleated cells in smokers and smokers + chewers, respectively, while it was weak negative and nonsignificant in chewers. In control group, correlation between age and percentage of micronucleated cells was weak positive and nonsignificant at 5% level of significance.</p><p><strong>Conclusion: </strong>The micronuclei in exfoliated mucosal cells from buccal mucosa can be used as a biomarker of genotoxicity in predicting the effects of carcinogens.</p>","PeriodicalId":30399,"journal":{"name":"Nigerian Journal of Surgery","volume":"25 1","pages":"52-59"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c7/92/NJS-25-52.PMC6452766.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37173242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Radiographic Evaluation of Anterior Loop of Inferior Alveolar Nerve: A Cone-Beam Computer Tomography Study.","authors":"Om Prakash,&nbsp;Pankaj Kumar Srivastava,&nbsp;Bhuvan Jyoti,&nbsp;Rafiya Mushtaq,&nbsp;Tarun Vyas,&nbsp;Purumandla Usha","doi":"10.4103/njs.NJS_1_18","DOIUrl":"https://doi.org/10.4103/njs.NJS_1_18","url":null,"abstract":"<p><strong>Background: </strong>A well awareness of the variation of inferior alveolar canal is mandatory to avoid iatrogenic complication. This study was conducted among 90 patients to determine variation in inferior alveolar nerve (IAN) loop through cone-beam computed tomography (CBCT) images.</p><p><strong>Materials and methods: </strong>CBCT images of 90 patients were involved in this study. All images were studied by the expert radiologist to see Type I, Type II, and Type III pattern of IAN canal (IANC). Results were subjected to statistical analysis for correct inferences.</p><p><strong>Results: </strong>Forty males and 50 females were included in the study. The difference was statistically nonsignificant (<i>P</i> = 0.5). Type I pattern was seen in 26 patients, Type II in 19, and Type III in 45 patients. The difference was statistically significant (<i>P</i> < 0.05). The most prevalent pattern was Type III (males - 15 and females - 30), followed by Type I (males - 14 and females - 12) and Type II (males - 11 and females - 8). There was statistical significance difference between males and females in Type II (<i>P</i> < 0.05).</p><p><strong>Conclusion: </strong>The anterior loop of IAC is quite common and IANC may show variation in structure. The most common pattern recorded was Type III. CBCT is very useful in the detection of IANC.</p>","PeriodicalId":30399,"journal":{"name":"Nigerian Journal of Surgery","volume":"24 2","pages":"90-94"},"PeriodicalIF":0.0,"publicationDate":"2018-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e8/9a/NJS-24-90.PMC6158995.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36554041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Crash Characteristics and Pattern of Motorcycle Related Facial Bone Fractures in a Sub-Urban Nigerian Teaching Hospital.","authors":"Obitade S Obimakinde,&nbsp;Oyebanji A Olajuyin,&nbsp;Taopheeq B Rabiu,&nbsp;Olusoji J Olanrewaju","doi":"10.4103/njs.NJS_39_17","DOIUrl":"https://doi.org/10.4103/njs.NJS_39_17","url":null,"abstract":"<p><strong>Context: </strong>Recent studies indicated that significant proportion of facial fractures attributed to road traffic mishaps in the middle- and low-income countries are caused by motorcycle (MC) crashes. However, there is limited information on crash characteristics of such injuries. This study was designed to examine the crash characteristics, pattern of fracture, and sociodemographics of patients with facial bone fractures due to MC crashes in our institution.</p><p><strong>Subjects and methods: </strong>Data on patients' sociodemographics, pattern of presentation, type(s) of fracture, patient status, crash characteristics, level of consciousness, and treatment offered were collected and analyzed.</p><p><strong>Results: </strong>A total of 151 patients, aged 7-59 years were reviewed during the study period. A male preponderance was observed (M:F = 4:1) and the patients were predominantly motorcyclists (64.8%, <i>n</i> = 98). The most common mechanism of crash was collision with another MC (51.6%, <i>n</i> = 78). A total of 194 fractures were reviewed and the mandible (58.8%, <i>n</i> = 114) was more commonly affected than the midface (41.2%, <i>n</i> = 80). The predominant site on the mandible was the body (31.6%) while zygoma (32.5%) was the most affected part of the midface. Patient status was found to have a statistically significant relationship with loss of consciousness (<i>P</i> = 0.02). Eighty-two fracture sites (42.3%) were managed with open reduction and internal fixation.</p><p><strong>Conclusions: </strong>Facial bone fractures occur in a significant proportion of MC crashes and riders are predominantly affected. In addition, a larger proportion of commuters rarely wear crash helmet which could have offered protection. Continual advocacy on preventive measures and enforcement of road safety regulations is hereby advised.</p>","PeriodicalId":30399,"journal":{"name":"Nigerian Journal of Surgery","volume":"24 2","pages":"71-75"},"PeriodicalIF":0.0,"publicationDate":"2018-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e7/79/NJS-24-71.PMC6158988.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36597358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Postcraniectomy Cranioplasty Using Autologous Split Calvarial Graft.","authors":"Saurabh Arya,&nbsp;Lalit Janjani","doi":"10.4103/njs.NJS_9_18","DOIUrl":"https://doi.org/10.4103/njs.NJS_9_18","url":null,"abstract":"Skull defects and craniofacial defects following head injuries may cause crippling and debilitating psychosocial ramifications on the life of a patient in terms of lost cosmesis, neurocognitive functions, and verbal expressions.[1,2] The reconstruction of large defects postcraniectomy has always been a challenge in the repertoire of maxillofacial surgeon. The maxillofacial surgeon plays an important role in decision‐making as regards to the timing of cranioplasty and counseling of the patient regarding the same. This 35‐year‐old patient who presented to us with “sinking skin flap syndrome” [Figure 1] postdecompressive craniectomy for evacuation of extradural hematoma was managed with a autogenous split‐calvarial bone graft [Figures 2 and 3] harvested from right parietal bone using the same incision [Figure 4]. An overall improvement in Letter to the Editor","PeriodicalId":30399,"journal":{"name":"Nigerian Journal of Surgery","volume":"24 2","pages":"142-143"},"PeriodicalIF":0.0,"publicationDate":"2018-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/dd/8d/NJS-24-142.PMC6158985.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36553956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tumor Necrosis Factor-Alpha and Interleukin-1 Alpha as Predictors of Survival in Peritonitis: A Pilot Study.","authors":"Oludolapo Ola Afuwape,&nbsp;Omobolaji O Ayandipo,&nbsp;Modupe Kuti,&nbsp;T A Adigun,&nbsp;O K Idowu","doi":"10.4103/njs.NJS_40_17","DOIUrl":"https://doi.org/10.4103/njs.NJS_40_17","url":null,"abstract":"<p><strong>Context: </strong>Peritonitis induces an inflammatory response characterized by the elevation of various cytokine levels. Included in this cascade of cytokines are tumor necrosis factor-alpha (TNF-α) and interleukin-1 alpha (IL-1α). The outcome of patient care may be associated with the pattern of elaboration of these cytokines.</p><p><strong>Aim: </strong>The aim of this study was to describe the pattern of cytokine response (TNF-α and IL-1α) in the course of peritonitis and evaluate them as predictors of mortality in peritonitis.</p><p><strong>Setting and design: </strong>This was a prospective study conducted in the Division of Gastrointestinal Surgery, University College Hospital, Ibadan.</p><p><strong>Methods: </strong>Consenting patients with clinical diagnosis of generalized peritonitis over a 6-month period (July to December 2015) were recruited. The serum samples of these patients were obtained at presentation, immediately after surgery, and 24 h and 48 h after surgery with a follow-up period of 30 days.</p><p><strong>Results: </strong>Twenty-six samples out of thirty could be analyzed. Serum TNF-α and IL-1α levels were both elevated at presentation in all patients. However, the patterns of change after intervention varied between the survivors and nonsurvivors.</p><p><strong>Conclusion: </strong>Peritonitis triggers a simultaneous increase in serum levels of TNFα and IL-1α. Lower serum level of TNF-α is associated with survival, while on the contrary, higher level of IL-1α is associated with survival.</p>","PeriodicalId":30399,"journal":{"name":"Nigerian Journal of Surgery","volume":"24 2","pages":"107-110"},"PeriodicalIF":0.0,"publicationDate":"2018-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/aa/cc/NJS-24-107.PMC6158982.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36554043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Clinical Study on Comparative Evaluation of the Effectiveness of Carbamazepine and Combination of Carbamazepine with Baclofen or Capsaicin in the Management of Trigeminal Neuralgia.","authors":"Nidhi Puri,&nbsp;Akshay Rathore,&nbsp;G Dharmdeep,&nbsp;Swapnil Vairagare,&nbsp;B Rajendra Prasad,&nbsp;R Priyadarshini,&nbsp;Harkanwal Preet Singh","doi":"10.4103/njs.NJS_8_18","DOIUrl":"https://doi.org/10.4103/njs.NJS_8_18","url":null,"abstract":"<p><strong>Background: </strong>Trigeminal neuralgia (TN) is characterized by recurrent attacks of lancinating pain in the trigeminal nerve distribution. Various medicinal and surgical procedures have been utilized for the treatment of TN. Over the time, several drugs other than carbamazepine have been used but none of them have shown satisfying results.</p><p><strong>Objective: </strong>The objective of the study is to evaluate the effectiveness of carbamazepine and combination of carbamazepine with baclofen or capsaicin in the management of TN.</p><p><strong>Materials and methods: </strong>A total of 45 patients diagnosed with TN were randomly divided into three groups. The patients were prescribed carbamazepine in Group 1, carbamazepine and baclofen in Group 2, and carbamazepine and capsaicin in Group 3. All the patients were followed on the 7^th day, 15^th day, and 1-month period to evaluate the response to the drugs. Data were subjected to statistics.</p><p><strong>Results: </strong>The results are composed of a total of 45 patients (15 in each group). The mean visual analogue scale scores were calculated for each group at day 0, 7^th day, 15^th day, and 30 days, and it was found that there was statistically significant reduction of pain (<i>P</i> < 0.001) in all the three groups at different intervals. At day 7, comparative percentage reduction of pain in both groups was not statistically significant. At 15-days and 30 days, percentage change in pain reduction in Group 1 was 42.3% and 48.0% respectively and in Group 2 it was found to be 60.3% and 83.4%, respectively. The reduction in pain percentage was found to be statistically significant. Similarly, Group 1 was compared to Group 3, significant reduction of pain was found for carbamazepine-capsaicin combination at 30-day interval but the comparative reduction of pain at 7^th day and 15^th day was not statistically significant.</p><p><strong>Conclusion: </strong>Carbamazepine in combination with baclofen is more efficient and effective in reducing pain in TN patients, followed by carbamazepine-capsaicin combination compared to carbamazepine alone.</p>","PeriodicalId":30399,"journal":{"name":"Nigerian Journal of Surgery","volume":"24 2","pages":"95-99"},"PeriodicalIF":0.0,"publicationDate":"2018-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/9f/29/NJS-24-95.PMC6158993.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36554045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Secretory Carcinoma of the Breast in a 20-year-old Male: Case Report and Review of Literature.","authors":"Abdurrahman Abba Sheshe,&nbsp;Mohammed Ibrahim Imam","doi":"10.4103/njs.NJS_42_17","DOIUrl":"https://doi.org/10.4103/njs.NJS_42_17","url":null,"abstract":"<p><p>Secretory breast carcinoma (SBC) is a very rare low-grade subtype of breast carcinoma. It was initially termed \"juvenile breast cancer,\" but it is now known to occur in adults of both sexes, and only few male cases have been reported in the literature. SBC is of importance because of its unique morphology and excellent prognosis. We report here a case in a 20-year-old male presenting with right pedunculated and ulcerated breast mass with associated contact bleeding. Histopathology was performed and it revealed a secretory carcinoma. This tumor is morphologically characterized by the presence of abundant eosinophilic secretions in intracellular vacuoles and intercellular spaces. The objective of this article is to review the epidemiological and clinical aspect of secretory carcinoma from a case report and literature review.</p>","PeriodicalId":30399,"journal":{"name":"Nigerian Journal of Surgery","volume":"24 2","pages":"135-137"},"PeriodicalIF":0.0,"publicationDate":"2018-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/84/8c/NJS-24-135.PMC6158987.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36553953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of Hunger Hormone \"Ghrelin\" in Long-Term Weight Loss Following Laparoscopic Sleeve Gastrectomy.","authors":"Pulkit Sethi,&nbsp;Manoj Thillai,&nbsp;Prabhdeep Singh Nain,&nbsp;Ashish Ahuja,&nbsp;Navpreet Aulakh,&nbsp;Preetika Khurana","doi":"10.4103/njs.NJS_24_17","DOIUrl":"https://doi.org/10.4103/njs.NJS_24_17","url":null,"abstract":"<p><strong>Introduction: </strong>Laparoscopic sleeve gastrectomy (LSG) has become a popular weight loss technique in morbidly obese patients. The aim of our study was to evaluate the changes in plasma ghrelin levels in relation to weight loss following LSG and to study the efficacy of LSG in terms of long-term glycemic control and resolution of diabetes.</p><p><strong>Methodology: </strong>The study was conducted on 70 morbidly obese patients (body mass index [BMI] >40 kg/m²) or severely obese patients (BMI >35 kg/m²) with comorbidities who underwent LSG in Dayanand Medical College and Hospital, Ludhiana, India. Ghrelin levels were measured preoperatively and postoperatively at 1 week, 3 months, and 6 months along with measurements of various weight loss parameters and glycosylated hemoglobin.</p><p><strong>Results: </strong>A significant decrease in plasma ghrelin levels was observed in relation to the mean weight and percentage excess weight loss at 3 months postoperatively. However, at 6 months, fall in ghrelin reached a plateau phase while weight loss was still sustained and significant. There was a significant fall in glycosylated hemoglobin levels with patients achieving good control/resolution of diabetes Type II.</p><p><strong>Conclusion: </strong>LSG is an effective weight loss surgery and brings about excellent weight loss in morbidly obese individuals in addition to achievement of good glycemic control in diabetic individuals. Serum levels of ghrelin fall significantly after sleeve gastrectomy. However, long term implications of ghrelin induced weight loss cannot be elucidated.</p>","PeriodicalId":30399,"journal":{"name":"Nigerian Journal of Surgery","volume":"24 2","pages":"121-124"},"PeriodicalIF":0.0,"publicationDate":"2018-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/45/ed/NJS-24-121.PMC6158981.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36553955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maxillectomy and Quality of Life: Experience from a Nigerian Tertiary Institution.","authors":"V I Akinmoladun,&nbsp;C A Akinyamoju,&nbsp;F O Olaniran,&nbsp;O I Olaopa","doi":"10.4103/njs.NJS_6_18","DOIUrl":"https://doi.org/10.4103/njs.NJS_6_18","url":null,"abstract":"<p><strong>Introduction: </strong>Maxillectomy is a surgical procedure for managing tumors affecting the maxilla; the goal of maxillectomy however should not be limited to tumor extirpation but should include restoration of oronasal function and facial contours, as failure to do these may give rise to psychosocial and functional challenges. This study aimed to appraise the pattern of maxillectomies, challenges of management, and quality of life (QOL) of a proportion of the study population.</p><p><strong>Materials and methods: </strong>This was a cross-sectional study carried out at the Department of Oral and Maxillofacial Surgery, University College Hospital, Ibadan. Patients' case files from year 2000 to 2016 were retrieved and reviewed. Data extracted for analysis included age, gender, site of lesion, and histologic diagnosis; lesions were grouped as benign or malignant. Contacts were made with patients or their next of kin for a clinic review appointment where QOL was assessed with the University of Washington Quality of Life version 4 Questionnaire. Data were analyzed and result presented as means and frequencies.</p><p><strong>Results: </strong>Out of the 78 cases of maxillectomy recorded in the department within the study period, records were available and adequate in 67 cases. There were 37 (55.2%) females with a mean age of 35.88 ± 14.9 years. Swelling was the most common reason for presentation (63, 94%). The mean period between onset of disease and presentation for treatment was 3.66 ± 3.35 years. Distribution of lesions was benign 35 (52.2%) and malignant 32 (47.8%). Hemi-maxillectomy was the commonest surgical procedure (23, 34.8%). While majority had some prosthetic rehabilitation, 31 participants (48.5%) obtained no prosthesis. Eight participants gave scores of ≥75% when comparing their present health-related QOL (HR-QOL) with a month before surgery; the overall QOL was ≥60%. However, HR-QOL and overall QOL in the last 7 days before assessment were rated as good in 55.6% and 66.7%, respectively. Chewing was the most important domain to participants.</p><p><strong>Conclusion: </strong>The pattern of presentation and indications for maxillectomy in this series are similar to that from previous studies. The uptake of prosthetic rehabilitation was low and overall QOL was rated as fair. QOL should be considered as part of treatment outcome measure for maxillectomy.</p>","PeriodicalId":30399,"journal":{"name":"Nigerian Journal of Surgery","volume":"24 2","pages":"125-130"},"PeriodicalIF":0.0,"publicationDate":"2018-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/cd/25/NJS-24-125.PMC6158980.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36554046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Histological Characteristics of Breast Lesions in Uyo, Nigeria.","authors":"Chukwuemeka Charles Nwafor,&nbsp;Isaac Assam Udo","doi":"10.4103/njs.NJS_29_17","DOIUrl":"https://doi.org/10.4103/njs.NJS_29_17","url":null,"abstract":"<p><strong>Background: </strong>The breast is a common site for pathologies which predominantly involves the female breast. While benign diseases are more common, malignancies are of utmost concern for the patient, clinician, and the pathologist.</p><p><strong>Aim: </strong>The aim of this study is to audit the clinical and pathological features of patients with breast lumps in a tertiary center in Nigeria.</p><p><strong>Materials and methods: </strong>This is a retrospective observational study of histologically diagnosed breast lumps over a period of 8 years.</p><p><strong>Results: </strong>Lumps were common in the 20-39 years age group (>50%), with a mean age of 34.95 years. Females accounted for 759 (98.1%) of cases. In 467 (60.4%) cases, the lumps measured >5 cm and only 175 (22.6%) cases presented to the surgeon within 12 weeks of noticing a breast lump. Ninety-one (11.8%) cases also presented with axillary lymph nodes, breast pain 79 (10.2%), peau d' orange 56 (7.2%), and ulceration 47 (6.1%). Benign breast disease (BBD) occurred in 401 (51.8%) cases and malignant breast diseases (MBD) occurred in 344 (44.3%) of cases.</p><p><strong>Conclusion: </strong>BBD and MBD are common among the young in Uyo. Lumps are the primary complaint and late presentation is the norm.</p>","PeriodicalId":30399,"journal":{"name":"Nigerian Journal of Surgery","volume":"24 2","pages":"76-81"},"PeriodicalIF":0.0,"publicationDate":"2018-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/37/94/NJS-24-76.PMC6158984.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36597359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}