Case Reports in Radiology最新文献

{"title":"Pulmonary Involvement in Proteus Syndrome: Clinical and Imaging Correlates in a Rare Case.","authors":"Cody Reid Johnson, Syed Muhammad Awais Bukhari, Amit Gupta","doi":"10.1155/crra/9944074","DOIUrl":"10.1155/crra/9944074","url":null,"abstract":"<p><p>Proteus syndrome is an uncommon, sporadic disorder characterized by progressive and heterogeneous overgrowth of tissues, resulting in distorted and asymmetric development. In most individuals, Proteus syndrome has minimal to no manifestations at birth but progresses during childhood and adolescence. Clinical manifestations of the disease include isolated asymmetric hemihyperplasia, isolated asymmetric macrodactyly, subcutaneous masses, plantar and palmar cerebriform fibrous overgrowth, exostoses, epidermal nevi, and scoliosis. Cardiothoracic structures are less commonly involved, and the manifestations include cystic lung changes, pulmonary thromboembolism and varicosities, and pulmonary nodules. Patients with Proteus syndrome have an increased risk of early death due to deep venous thrombosis and pulmonary embolism. We report a case of an adult female who was diagnosed with Proteus syndrome at the age of 5 years who had multiple pulmonary manifestations of the disease.</p>","PeriodicalId":30326,"journal":{"name":"Case Reports in Radiology","volume":"2026 ","pages":"9944074"},"PeriodicalIF":0.0,"publicationDate":"2026-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12782245/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145953266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"To Kill the Calyces: A Rare Case of Xanthogranulomatous Pyelonephritis Complicated by Emphysematous Pyelonephritis.","authors":"Brandon Simons, Aaron Geril, Amir Hedayati","doi":"10.1155/crra/7650184","DOIUrl":"10.1155/crra/7650184","url":null,"abstract":"<p><p>Xanthogranulomatous pyelonephritis (XPN) is a rare chronic renal infection associated with obstructive nephrolithiasis and recurrent urinary tract infections. Emphysematous pyelonephritis (EPN) is an even rarer necrotizing infection characterized by intrarenal gas, most commonly seen in patients with uncontrolled diabetes mellitus. Concurrent presentation of XPN and EPN is exceedingly uncommon, with only a few cases reported. We present a case of a 61-year-old female with no history of diabetes who presented with left flank pain, systemic symptoms, and laboratory evidence of infection and microcytic anemia. Abdominal CT revealed imaging features consistent with XPN-including hydronephrosis, a staghorn calculus, and the classic \"bear paw\" sign-alongside intrarenal gas, consistent with EPN. Urine culture grew <i>Proteus mirabilis</i>. The patient underwent nephrectomy and recovered uneventfully with antimicrobial therapy. This case is notable for the rare co-occurrence of XPN and EPN in a euglycemic patient, supporting the hypothesis that chronic obstruction and infection may be sufficient to induce gas-forming infections, even in the absence of hyperglycemia. Awareness of atypical presentations is essential, as early recognition and surgical management are critical to reducing morbidity in these severe renal infections.</p>","PeriodicalId":30326,"journal":{"name":"Case Reports in Radiology","volume":"2025 ","pages":"7650184"},"PeriodicalIF":0.0,"publicationDate":"2025-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12662668/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145649186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metastatic Merkel Cell Carcinoma Incidentally Detected on PSMA PET/CT in a Patient With Metastatic Prostate Cancer.","authors":"William Y Raynor, Manas Ranpariya, Jeffrey S Kempf, Biren Saraiya, Sarah A Weiss","doi":"10.1155/crra/1751973","DOIUrl":"10.1155/crra/1751973","url":null,"abstract":"<p><p>Positron emission tomography (PET) radiotracers targeting prostate-specific membrane antigen (PSMA) are now widely used in the evaluation of prostate cancer. However, PSMA activity has also been described in several nonprostatic malignancies, where PSMA is primarily expressed in tumor neovasculature. Here, we describe to the best of our knowledge the first case of a PSMA-avid Merkel cell carcinoma (MCC) inguinal lymph node metastasis, detected incidentally in an 80-year-old man with advanced metastatic prostate adenocarcinoma. Clinical history and disease distribution prompted the need for a diagnostic biopsy, confirming PSMA-avid metastatic MCC. This case highlights the importance of recognizing nonprostatic causes of PSMA uptake, as synchronous malignancies can alter diagnostic interpretation and treatment planning.</p>","PeriodicalId":30326,"journal":{"name":"Case Reports in Radiology","volume":"2025 ","pages":"1751973"},"PeriodicalIF":0.0,"publicationDate":"2025-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12595225/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145483196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PSMA PET/CT Incidental Detection of Tumor Thrombus From Unsuspected Renal Cell Carcinoma and Comparison with FDG PET/CT.","authors":"William Y Raynor, Stephen J Sozio, Anthony Yudd, Tina Mayer, Jeffrey S Kempf","doi":"10.1155/crra/8358399","DOIUrl":"10.1155/crra/8358399","url":null,"abstract":"<p><p>Clear cell renal cell carcinoma (ccRCC) is typically prostate-specific membrane antigen (PSMA)-avid, likely related to PSMA expression in the tumor neovasculature, suggesting a potential role for evaluation by PSMA PET/CT. We describe a 77-year-old patient with prostate cancer who was incidentally found to have ccRCC on imaging with PSMA PET/CT, with subsequent staging by FDG PET/CT. He was diagnosed with prostate cancer 17 years prior and treated with radical prostatectomy and radiation therapy within a year of diagnosis. Biochemical recurrence with PSA of 1.0 ng/mL prompted imaging with PSMA PET/CT, which showed an unexpected finding of abnormal uptake within the right renal vein and inferior vena cava (IVC), suggesting possible tumor thrombus (SUVmax 8.8), with mild uptake corresponding to a suspected right renal mass. In addition, there was a PSMA-avid right paratracheal nodal metastasis measuring 3.3 cm (SUVmax 8.4). Subsequent FDG PET/CT again showed the renal mass, tumor thrombus (SUVmax 3.6), and only low-level uptake in the right paratracheal mass (SUVmax 2.3). Right nephrectomy was performed, confirming the presence of ccRCC in the right kidney with tumor thrombus extending to the right renal vein and IVC. FDG PET/CT restaging showed no recurrence in the nephrectomy bed and a stable FDG-avid right paratracheal mass. After stereotactic body radiation therapy (SBRT) directed to the right paratracheal mass, follow-up PSMA PET/CT showed decreased uptake (SUVmax 4.8), suggesting its usefulness for detecting and monitoring ccRCC.</p>","PeriodicalId":30326,"journal":{"name":"Case Reports in Radiology","volume":"2025 ","pages":"8358399"},"PeriodicalIF":0.0,"publicationDate":"2025-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12588747/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145459704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Late-Onset Nonhereditary Cherubism: First Reported Case in Ghana With Review of Diagnostic and Management Challenges.","authors":"Seth Kwadjo Angmorterh, Mariella Mawunyo Amoussou-Gohoungo, Adam Inusah, Bridgette Palm, Kafui Kossi Kekessie, Riaan van de Venter, Sonia Aboagye, Cosmos Yarfi, John Nsor-Atindana, Portia Mamle Angmorterh, Klenam Dzefi-Tettey","doi":"10.1155/crra/5333205","DOIUrl":"10.1155/crra/5333205","url":null,"abstract":"<p><strong>Background: </strong>Cherubism is a rare genetic disorder characterised by multilocular cystic lesions in the mandible and/or maxilla, which result in the typical cherub-like face. Two forms of cherubism exist-hereditary (familial) and nonhereditary (nonfamilial)-and it usually occurs amongst children aged 2-7 years. The disorder is caused by a mutation in the SH3BP2 gene on Chromosome 4p16.3, essential for jaw development. The prognosis of cherubism shows that lesions increase in size and plateau at puberty, after which the lesions begin to regress and become undetectable. We present the first case of cherubism to be reported from Ghana.</p><p><strong>Case presentation: </strong>Our case is a nonhereditary (nonfamilial) cherubism in a 21-year-old Ghanaian woman. The patient presented with bilateral asymmetrical facial swelling, jaw pain, trismus, toothache, tooth mobility and tooth loss. Also, the patient had facial disfigurement, weight loss, cough, headache, seizures and dizziness. Her family history was noncontributory. The results of a head computed tomography (CT) scan indicated chronic left sphenoid sinusitis and an enlargement of the entire mandible, with multilocular expansile lytic (soap bubble) appearance. The mandibles had ground glass matrix areas associated with subtle cortical destruction and dental deformities suggestive of Grade III cherubism.</p><p><strong>Discussion and conclusion: </strong>Our patient had the onset of the disorder at age 12 but presented to the hospital at the age of 21. The reason why our patient did not seek medical help beforehand could be attributed to sociocultural beliefs, financial constraints and/or limited access to healthcare amenities. Treatment protocols for cherubism may include observation, surgery and medical therapy. Our patient resorted to the use of traditional medicine and spiritual/religious consultations for treatment. Our patient experienced discrimination due to the disease and had lost job, friendship and romantic relationship opportunities because of cultural beliefs, stereotypes and stigmatisation. Her facial disfigurement and the deformities are associated with bad omens and negative spirits in Ghana. When diagnosed, patients suffering from cherubism must be encouraged to seek information, education and appropriate individualised evidence-based management from hospitals. Treatment of the disease should be supported with psychological counselling and community sensitisation wherever possible.</p>","PeriodicalId":30326,"journal":{"name":"Case Reports in Radiology","volume":"2025 ","pages":"5333205"},"PeriodicalIF":0.0,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12527603/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145309371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Visualization of Intrapulmonary Lymphadenopathy on Vessel-Suppressed Computed Tomography in a Patient With Sarcoidosis.","authors":"Seitaro Ishikawa, Atsushi Takamatsu, Kotaro Yoshida, Miho Okuda, Satoshi Kobayashi","doi":"10.1155/crra/3546986","DOIUrl":"10.1155/crra/3546986","url":null,"abstract":"<p><p>We report a case of a 55-year-old woman diagnosed with sarcoidosis involving multiple intrapulmonary lymph nodes that were clearly visualized on vessel-suppressed CT imaging. Intrapulmonary lymph node involvement in patients with sarcoidosis has been reported less frequently and has not been well discussed. This may be attributed to the fact that intrapulmonary lymph nodes present as small nodular lesions located along pulmonary vessels, making them difficult to detect on conventional imaging. Vessel-suppressed CT enhances visualization of pulmonary lesions by selectively suppressing vascular structures. This case highlights the clinical utility of vessel-suppressed CT for improved detection of intrapulmonary lymph node lesions in the diagnosis of sarcoidosis.</p>","PeriodicalId":30326,"journal":{"name":"Case Reports in Radiology","volume":"2025 ","pages":"3546986"},"PeriodicalIF":0.0,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12457050/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145138354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Radiographic Identification of Foreign Bodies in the Maxillofacial Region: A Case Report and Review for Aesthetic Surgery Planning.","authors":"Sekina Alimova, Yehya Tlaiss, Suzanne Youness, Ahmad Tleis, Basin Evgeny, Victor Truten, Tatiana Guseva","doi":"10.1155/crra/8870515","DOIUrl":"10.1155/crra/8870515","url":null,"abstract":"<p><p>Aesthetic facial and neck procedures increasingly rely on radiographic imaging for surgical planning and complication management. Cone-beam computed tomography (CBCT) offers high-resolution, three-dimensional imaging, but foreign materials such as cosmetic fillers and metallic implants can mimic pathology, generate artifacts, and complicate surgery. This case report with an integrated literature review highlights the radiographic identification of such materials and their implications for aesthetic procedures, illustrated by a patient case where CBCT revealed high-density inclusions in the submental region, correlating with intraoperative fibrosis and extended surgical time. CBCT proved superior in visualizing foreign bodies with lower radiation exposure than conventional CT, emphasizing the need for standardized imaging protocols and AI-driven artifact reduction to enhance diagnostic accuracy and optimize surgical outcomes.</p>","PeriodicalId":30326,"journal":{"name":"Case Reports in Radiology","volume":"2025 ","pages":"8870515"},"PeriodicalIF":0.0,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12422837/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145041562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Benign Enchondroma in a 40-Year-Old Female: Emphasizing the Importance of Early 18F-FES PET/CT Utilization.","authors":"Tamer M Dawud, Abdullah T Dawud","doi":"10.1155/crra/9992200","DOIUrl":"10.1155/crra/9992200","url":null,"abstract":"<p><p>A 40-year-old female with estrogen receptor-positive breast cancer underwent an initial staging using a technetium-99m methylene diphosphonate (Tc-99m MDP) bone scan, which revealed abnormal uptake in the femur without a patient history of prior trauma or associated symptoms. Subsequently, an MRI confirmed the presence of a well-defined lesion in the upper left femur. To rule out metastatic disease, an 18F-fluoroestradiol (FES) PET/CT was performed, demonstrating no ER expression. Following the PET/CT, a biopsy confirmed the presence of an enchondroma. This case underscores the importance of early utilization of 18F-FES PET/CT in breast cancer staging to minimize unnecessary additional procedures/imaging.</p>","PeriodicalId":30326,"journal":{"name":"Case Reports in Radiology","volume":"2025 ","pages":"9992200"},"PeriodicalIF":0.0,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12339146/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144822755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cerebral and Portal Venous Air Embolism: A Complication of PICC Line Placement.","authors":"Gizem Reyhanoglu, Dominika Moscicka, George Guirguis, Mina S Mousa","doi":"10.1155/crra/5236025","DOIUrl":"10.1155/crra/5236025","url":null,"abstract":"<p><p>Cerebral air embolism is a rare and potentially fatal medical condition that requires prompt recognition and management. Iatrogenic causes such as laparoscopic procedures, hysteroscopy, or central venous catheter (CVC) manipulation are well-documented etiologies. This article presents a case of an 80-year-old female who developed iatrogenic air emboli from CVC manipulation leading to left middle cerebral artery (MCA) syndrome due to suspected right-to-left shunt from pulmonary arteriovenous malformation (pulmonary AVM) or patent foramen ovale (PFO). Preexisting neurological deficits, elevated lactate levels, and sepsis with evidence of systemic hypoperfusion on admission hindered the early detection and treatment of air emboli. This case highlights the need for heightened awareness of CVC-related iatrogenic air embolism, particularly in patients with predisposing conditions such as pulmonary AVM and PFO. Comprehensive treatment strategies, including hyperbaric oxygen therapy, remain critical for achieving better outcomes.</p>","PeriodicalId":30326,"journal":{"name":"Case Reports in Radiology","volume":"2025 ","pages":"5236025"},"PeriodicalIF":0.0,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12297144/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144733653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perforated Gastric Ulcer With GI Bleeding Secondary to Cystic Artery Pseudoaneurysm.","authors":"Akhil Tanwar, Surbhi Singh, Jennifer Hubert, Dhrumil Patel","doi":"10.1155/crra/2255883","DOIUrl":"10.1155/crra/2255883","url":null,"abstract":"<p><p>This case study presents an 87-year-old female patient with a history of chronic abdominal pain and NSAID use who was admitted with symptoms of hematemesis and melena, indicative of upper gastrointestinal bleeding. Upon examination, she was found to be hemodynamically stable but exhibited signs of moderate protein-calorie malnutrition. Imaging studies, including a multiphasic CT angiogram, revealed a contained rupture in the distal stomach, and a cystic artery pseudoaneurysm measuring 4.2 mm. Despite the presence of a perforated ulcer, there was no significant pneumoperitoneum or hemoperitoneum, leading to a diagnosis of contained perforation. The management plan included conservative treatment with IV antibiotics, proton pump inhibitors, and monitoring of hemodynamic status. On the third day of admission, the decision was made to embolize the cystic artery, as the risk of gallbladder ischemia was deemed low. This case underscores the critical need for prompt diagnosis and intervention in patients presenting with upper GI bleeding, particularly in the elderly, where the mortality rate can be significantly high. The findings emphasize the importance of imaging in localizing the source of bleeding and guiding appropriate management strategies.</p>","PeriodicalId":30326,"journal":{"name":"Case Reports in Radiology","volume":"2025 ","pages":"2255883"},"PeriodicalIF":0.0,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12245491/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144609690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}