Romanian Neurosurgery最新文献_第5页

Therapeutic advances in treatment of patients with neurofibromatosis type 1 and type 2 1型和2型神经纤维瘤病的治疗进展

Romanian Neurosurgery Pub Date : 2023-01-05 DOI: 10.33962/roneuro-2022-071

G. Popescu, Francesca Paslaru, M.C. Zaharia, M. Popescu, R.M. Gorgan

{"title":"Therapeutic advances in treatment of patients with neurofibromatosis type 1 and type 2","authors":"G. Popescu, Francesca Paslaru, M.C. Zaharia, M. Popescu, R.M. Gorgan","doi":"10.33962/roneuro-2022-071","DOIUrl":"https://doi.org/10.33962/roneuro-2022-071","url":null,"abstract":"Background: Neurofibromatosis type 1 (NF1) and neurofibromatosis type 2 (NF2) are rare tumoral suppressor syndromes, triggered by an abnormal mutation in a tumour suppressor gene (TSG) (1). Each of these syndromes represents an orphan disease (by itself), but the tumours encountered in these patients are the most frequent lesions of the nervous system. Between the two of these diseases, NF1 presents a greater risk of malignancy, hence the importance of an accurate diagnosis and distinction between the two pathological entities. The purpose of this paper is to describe our department's practice protocol with neurofibromatosis and review the current literature regarding clinical diagnosis and management of these complex diseases. Methods: Our paper is a retrospective study that comprehends 25 patients with neurofibromatosis treated in our clinic between 2011 and 2018. Results: Our study included 16 female patients (64%) and 9 male patients (36%). The mean age at presentation was 48,7 (range 14-72 years). There were 7 cases (28%) of NF1 and 18 cases (72%) of NF2. Seven cases (28%) had a positive family history and 18 patients did not (72%). The most common symptoms at presentation were hearing loss, vertigo, and headache. Conclusions: Neurofibromatosis is a very complex disease in which the tumours may have an unforeseeable growth pattern. New tumours can grow over the years and the symptoms are unpredictable. Surgical treatment is best to be reserved for symptomatic tumours. Non-surgical procedures are also an important step of the treatment, but further studies are required to decide their effectiveness.","PeriodicalId":30188,"journal":{"name":"Romanian Neurosurgery","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135405113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Steps towards neuro-excellence 迈向卓越的神经系统

Romanian Neurosurgery Pub Date : 2023-01-05 DOI: 10.33962/roneuro-2022-070

Alexandru Vlad Ciurea, Andrei Adrian Popa

引用次数: 0

PICA ischemic stroke 异食癖缺血性中风

Romanian Neurosurgery Pub Date : 2023-01-05 DOI: 10.33962/roneuro-2022-076

Razvan Adrian Covache-Busuioc, Horia Petre Costin, Vicentiu Mircea Saceleanu

引用次数: 0

Brain abscess – a still high mortality medical condition 脑脓肿——一种死亡率仍然很高的疾病

Romanian Neurosurgery Pub Date : 2023-01-05 DOI: 10.33962/roneuro-2022-073

George Popescu, Marius C. Zaharia, Ana-Maria Georghiu, Bogdan-Ionuț David, Ana-Maria Ioniță, Cezar Vijlanescu, Radu M. Gorgan

{"title":"Brain abscess – a still high mortality medical condition","authors":"George Popescu, Marius C. Zaharia, Ana-Maria Georghiu, Bogdan-Ionuț David, Ana-Maria Ioniță, Cezar Vijlanescu, Radu M. Gorgan","doi":"10.33962/roneuro-2022-073","DOIUrl":"https://doi.org/10.33962/roneuro-2022-073","url":null,"abstract":"Background. Even in the 21st century, infections of the central nervous system and their secondary damage still represents a high mortality condition. Furthermore, brain abscesses (BA) are huge public health issues due to their high mortality and morbidity with high financial implications for the health care system. Material and methods. In this article, we want to present our clinic`s experience in the management of brain abscesses between 2012 and 2021. A 10 years retrospective study was performed in the 4th Neurosurgery Department of “Bagdasar-Arseni” Clinical Emergency Hospital in Bucharest Results. In the last 10 years, our clinic admitted 46 patients, 10 women and 36 men. The mean age was 47 years old. The most common symptom was headache (42 cases). In 39 cases, patients had solitary abscesses while seven patients presented multiple abscesses. The therapeutic approach was classic surgery in 37 cases. In four cases abscess drainage was performed and in five cases conservative treatment was used. At discharge, 31 patients were healed and seven patients died. Discussions. In BA management, antimicrobial therapy is crucial. Thus, identifying the pathogen is crucial for accurate antimicrobial treatment. Unfortunately, in too many cases, the agent remains unknown and empiric treatment is required. Aspiration of the abscesses proved to be safe and with similar results compared to classic surgery. Conclusions. Brain abscesses remain a high challenge to manage even in the 21st century. Broad-spectrum antibiotic treatment should be applied as soon as possible until the pathogen is identified and specific treatment will be used.","PeriodicalId":30188,"journal":{"name":"Romanian Neurosurgery","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135405115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intracranial aneurysms - a battle against time 颅内动脉瘤——一场与时间的战斗

Romanian Neurosurgery Pub Date : 2023-01-05 DOI: 10.33962/roneuro-2022-074

Corneliu Toader, Andrei Alexandru Marinescu, Andrei Adrian Popa, Bogdan Gabriel Bratu, Alexandru Vlad Ciurea

引用次数: 0

Giant, primary, hydatid cyst of the gluteal region 臀区巨大的原发性包虫病

Romanian Neurosurgery Pub Date : 2021-12-21 DOI: 10.33962/roneuro-2021-071

G. Iacob, R. Roşiu, M. Luchian, G. Simion

{"title":"Giant, primary, hydatid cyst of the gluteal region","authors":"G. Iacob, R. Roşiu, M. Luchian, G. Simion","doi":"10.33962/roneuro-2021-071","DOIUrl":"https://doi.org/10.33962/roneuro-2021-071","url":null,"abstract":"Background: Primary hydatid disease in the muscle is extremely rare, resulting in either the spread of cysts spontaneously or after operations for hydatidosis in distant regions. \u0000Methods: Report of an unusual case of primary hydatid cyst in the gluteus muscle, behaving as enlarging soft-tissue tumour, with a review of the literature. \u0000Results: Magnetic resonance imaging revealed an intramuscular cyst in the gluteus muscle; and no cyst existed in any other location. The cyst was excised totally, and the diagnosis of muscular cystic hydatidosis was confirmed by histopathologic examination. In follow-up of two years after the operation, there has been no recurrence in either patient. \u0000Conclusion: The involvement of the gluteus maximus muscle without the evidence of hepatic or pulmonary disease is rare, characterized by slow development, but a major local extension must be considered in the differential diagnosis of a cystic mass with well-defined margins in the extremities of individuals from endemic regions. Physical examination, serology results and radiological findings should be interpreted with care, especially in hydatid cyst endemic countries. Surgery is still the treatment of choice, with total cyst excision.","PeriodicalId":30188,"journal":{"name":"Romanian Neurosurgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46586293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unpublished data on the founder of Romanian Neurosurgery – Professor Dumitru Bagdasar 罗马尼亚神经外科创始人Dumitru Bagdasar教授的未发表数据

Romanian Neurosurgery Pub Date : 2021-12-21 DOI: 10.33962/roneuro-2021-067

H. Berceanu, S. Groppa, H. Pleș

{"title":"Unpublished data on the founder of Romanian Neurosurgery – Professor Dumitru Bagdasar","authors":"H. Berceanu, S. Groppa, H. Pleș","doi":"10.33962/roneuro-2021-067","DOIUrl":"https://doi.org/10.33962/roneuro-2021-067","url":null,"abstract":"Dumitru Bagdasar, who is indisputably considered as the founder of neurosurgery on the Romanian territory during the interwar period, was born in Ro?ie?ti, the former F?lciu County, in 1893. In 1913, after having completed his primary and secondary education, he enrolled at the Faculty of Medicine of Bucharest and, in the summer of 1916, at the end of his third university year, he transferred to the Medical Military Institute. From 1916 to 1918, D. Bagdasar dealt with the whole array of illnesses arising from the world conflict, including firearm-related injuries to the nervous system. After the war, he was transferred to the Neurology Clinic of the Colentina Hospital where, under the supervision of Professor Gheorghe Marinescu, he elaborated and completed his doctoral dissertation entitled: Contribu?iuni la studiul Sindromului Parkinsonian-postencefalitic (Contributions to the Study of Postencephalitic Parkinsonism), which he defended in 1922. From 1922 to 1926, at the Military Hospital of Bucharest, he completed his neurology internship under the guidance of the eminent neurologist Dumitru Noica and his initiation to surgery under Professor Mihail Butoianu. In 1927, after giving up his military contract, he was transferred to the Jimbolia Hospital by the Ministry of Health to work as an attending neuropsychiatrist. At the end of the same year, with a recommendation from Professor Nicolae Paulescu, he earned a neurosurgery specialisation scholarship under Professor Harvey Cushing in Boston. There, under the guidance of Professor Cushing and Doctor Bailey, he wrote two papers: Le traitement Chirurgical des gommes cérébrales and Intracranial Chordoblastoma, which were published in prestigious medical journals. In 1929, he returned to the Jimbolia Hospital where, in 1930, he performed his first neurosurgical procedures. At the end of 1931, he transferred to the Cern?u?i Hospital, again as a neuropsychiatrist, and in the following two years he performed a number of 149 operations on the central nervous system, which are described in the surgical reports written by Doctor Bagdasar himself. In 1934, he transferred to Bucharest, where he performed neurosurgical procedures in two hospitals (Emergency Hospital and Central Hospital) and, at the end of the same year, he was tenured as an attending neurosurgeon at the Central Hospital, following a contest organised by the Ministry of Health. From 1935, he worked primarily in the aforementioned hospital but he also performed operations in other hospitals (Emergency, Col?ea, Military etc.). Alongside his surgical activity, he was also interested in the histopathology of the operated tumours, he wrote scientific papers based on his own case reports, participated in medical congresses (Bucharest, Bern, Chisinau etc.) and became interested in the social-political issues of the time..., joining the Communist Party in 1943. In 1940, just before the outburst of World War II, he wrote Acute craniocerebral trauma and","PeriodicalId":30188,"journal":{"name":"Romanian Neurosurgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42939962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinicopathological features, imaging characteristics and surgical management in a novel tumour entity - aggressive meningiomas 新型肿瘤侵袭性脑膜瘤的临床病理特征、影像学特征及手术治疗

Romanian Neurosurgery Pub Date : 2021-12-21 DOI: 10.33962/roneuro-2021-069

G. Popescu, F. Paslaru, A. Paslaru, M. Apostol, M. Zaharia, T. Corneliu, M. Mitrica, M. Popescu, R. M. Gorgan

{"title":"Clinicopathological features, imaging characteristics and surgical management in a novel tumour entity - aggressive meningiomas","authors":"G. Popescu, F. Paslaru, A. Paslaru, M. Apostol, M. Zaharia, T. Corneliu, M. Mitrica, M. Popescu, R. M. Gorgan","doi":"10.33962/roneuro-2021-069","DOIUrl":"https://doi.org/10.33962/roneuro-2021-069","url":null,"abstract":"Meningiomas are common neoplasms of the central nervous system, comprising between 24 and 30% of primary intracranial tumours, most commonly affecting females in their middle age or later adult life [1] [2]. \u0000Meningiomas are classified as benign, atypical or anaplastic meningiomas depending mostly on histopathological criteria known to be associated with worse prognosis in terms of tumour progression, recurrence risk after surgery and overall survival. The 2016 edition of the World Health Organization (WHO) classification of Central Nervous System (CNS) tumours recognizes brain invasion as an independent criterion for diagnosing an atypical grade II meningioma [3]. Meningioma grading based on the WHO classification of CNS tumours thoroughly impacts therapeutic management and tumour prognosis. \u0000Aggressive meningiomas, a different phenotype of tumours, characterized by rapid growth and involvement of adjacent brain tissue, blood vessels and bone, was not previously listed as an independent entity in the WHO classification of meningothelial-cell tumours. \u0000Regarding the increasing importance of tumour grading in meningioma treatment strategies, the authors here provide an overview of clinicopathological and radiographic features, surgical management and long-term prognosis of this novel meningothelial tumour entity, the aggressive meningioma. In particular, we aimed to describe pre-, intra- and postoperative methods for recognizing aggressive meningiomas and explore the implications of this diagnosis on both surgical strategies and adjuvant therapy.","PeriodicalId":30188,"journal":{"name":"Romanian Neurosurgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42836872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Schwannoma of the digital nerve 指神经神经鞘瘤

Romanian Neurosurgery Pub Date : 2021-12-21 DOI: 10.33962/roneuro-2021-083

V. Aleksić, Jovan Prelić, Matija Radojević, R. Ćulafić

引用次数: 2

Important controversies in lumbar spine surgery: which patients benefit from lumbar spinal fusion and who should be fused? 腰椎手术中的重要争议：哪些患者从腰椎融合术中受益，谁应该进行融合术？

Romanian Neurosurgery Pub Date : 2021-12-21 DOI: 10.33962/roneuro-2021-072

F. Urian, G. Iacob, A. V. Ciurea

{"title":"Important controversies in lumbar spine surgery: which patients benefit from lumbar spinal fusion and who should be fused?","authors":"F. Urian, G. Iacob, A. V. Ciurea","doi":"10.33962/roneuro-2021-072","DOIUrl":"https://doi.org/10.33962/roneuro-2021-072","url":null,"abstract":"Considering the rising tendency in the application of lumbar spine devices, a rigorous selection of candidates for lumbar spinal fusion must follow the benefit of the patient in terms of a better outcome than classical techniques or conservatory treatment. We pulled essential information from scientific sources regarding the clinical results of patients who underwent fusion surgery to sift patients who do better from fusion. \u0000We found out that imagistic proof of instability such as spondylolisthesis associated with lumbar spinal stenosis and refractory pain takes the most from spinal fusion procedures. Oswestry disability index improvement along with restoring the function and reduction of pain remained the postoperative desires of a successful fusion. Clinical amelioration with bracing test prior to intervention was a predictor of better results after fusion. Exclusion criteria like psychiatric disorders and prior lumbar spine surgery were highlighted since studies demonstrated that they are bad predictors of outcome in spinal fusion surgery. \u0000Laminectomy was nowhere implemented in the literature as to be urgently fused since only about 20% of patients manifest instability after this classical procedure. Iatrogenic segmental instability after laminectomy, radiologically proven should be a candidate for spinal fusion. These procedures have high costs and high rates of complications putting the patient’s functional status and quality of life at uncertainty since there is still a lot of debate in this area of spinal neurosurgery.","PeriodicalId":30188,"journal":{"name":"Romanian Neurosurgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41788084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0