International Journal of Pregnancy & Child Birth最新文献

{"title":"Good pasture’s syndrome diagnosed in postpartum period: acute kidney injury severe enough to warrant renal transplant","authors":"S. Veeramalla, Aashima Arora, Geetika Thakur, R. Ramachandran, S. Soni","doi":"10.15406/ipcb.2021.07.00235","DOIUrl":"https://doi.org/10.15406/ipcb.2021.07.00235","url":null,"abstract":"Objective: Goodpasture's syndrome (GPS) is the association of pulmonary haemorrhage with acute kidney injury (AKI) resulting from injury by auto-antibodies. Its de novo occurrence in pregnancy is extremely rare with only few cases reported. High risk of mortality and lack of consensus in treatment warrants its reporting. Case report: A 24 year old primigravida, with no history suggestive of renal disease, presented to us in her third trimester with anuria. She was initially managed as sepsis or preeclampsia related AKI. However, even after delivery there was no improvement in kidney function with hemodialysis and she developed hemoptysis. Renal biopsy made a diagnosis of Anti-Glomerular Basement Membrane disease. With careful multi-disciplinary treatment, she delivered a live born baby and was discharged under stable condition on hemodialysis, currently awaiting a kidney transplant. Conclusion: This case highlights that the current management for GPS should be revised to improve the outcome of AKI. Also, it determines how important it is for obstetricians to consider whether a pregnancy should be terminated to improve the outcome of AKI in pregnant patients with GPS","PeriodicalId":300833,"journal":{"name":"International Journal of Pregnancy & Child Birth","volume":"339 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134049259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Drug usage pattern and potential teratogenesity risk among pregnant women attending maternal and child health clinic of Mettu Karl Referral Hospital, South Western, Ethiopia: a cross sectional study, 2021","authors":"Gudisa Bereda, Gemechis Bereda","doi":"10.15406/ipcb.2021.07.00234","DOIUrl":"https://doi.org/10.15406/ipcb.2021.07.00234","url":null,"abstract":"Introduction: Physiological alterations during pregnancy as well as the bio- conversion of compounds can significantly influence the teratogenic effects of drugs and chemicals by affecting absorption, body distribution, the active form(s), and excretion of the compound. Certain medications may cause harm to the foetus due to their potential teratogenic effects and the physiological adjustments occurring in the mother during pregnancy. Prescription of drug used by pregnant women should be viewed as one of a public health issue. This study aware health care workers on harmful drugs prescription to pregnant women and helps in understanding the type of medication used during pregnancy and safety of drugs used during pregnancy, thereupon this study was ascertain drug usage pattern and potential teratogenicity risk among pregnant women attending maternal and child health clinic of Mettu Karl Referral Hospital. Methods: A hospital-based cross-sectional study design was carried out from April 13/2021 to June 15/2021. Data was collected through employing semi-structured questioner, and then the collected data was cleared, coded and analyzed by statistical packages for social sciences 25.0 version statistical software. Descriptive statistics were used to describe the data. P value <0.05 was considered as a cut point for statistical significance in the final model. Results: A total of 156 participants were interviewed of whom, 81(51.9%) pregnant women were age between 20-35 years old and a majority 113(72.4%) of them were married. Among medical condition majority 40(25.6%) of the participants had peptic ulcer disease and 26(16.7%) urinary tract infections followed by 20(12.8%) acute illness and 12(7.7%) hyperemesis. Among the total drug prescribed for pregnant women 30(19.2%) FDA category C was the common followed by 29 (186%) FDA category B and 26(16.7%) FDA category D. Only 10(6.4%) of prescribed drug were FDA category X. Pregnant women whose age >35 years (AOR=4.05, 95%CI:1.274-1.903; p=0.001), urban residents (AOR=2.72, 95%CI:2.524-3.927; p=0.035), and pregnant women during second trimester (AOR=1.79, 95%CI:3.926-9.406; p=0.013) were significantly associated with MCH follow up. Conclusion and recommendation: From the drug prescribed, majority of pregnant women were taken antibiotics followed by 18(11.5%) NSAID, iron sulfate, and proton pump inhibitors. Among the dosage form, above half of the participants were taken the tablet dosage form followed by capsule and gels dosage form. Health care workers should have to brought good care for pregnant women, since they perhaps vulnerable to drug teratogenesity","PeriodicalId":300833,"journal":{"name":"International Journal of Pregnancy & Child Birth","volume":"70 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123587878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Unique case report of successful pregnancy and delivery after being treated with pioglitazone and glimepiride (in first three months)","authors":"Nirmalya Roy, S. Sarkar, Ankan Pathak, Nikhil Sonthalia","doi":"10.15406/ipcb.2021.07.00233","DOIUrl":"https://doi.org/10.15406/ipcb.2021.07.00233","url":null,"abstract":"A planned pregnancy (with IVF) in a patient with type 2 diabetes was treated with insulin along with glimepiride and pioglitazone (treated in first three months) from pre-conception stages until the postpartum is reported. She delivered a single viable male child at 33 weeks of gestation due to pregnancy induced hypertension and type 2 diabetes mellitus with no abnormalities. The newborn was healthy without any congenital and other abnormalities. To our belief, this is the first case reporting the use of pioglitazone as well as glimepiride in early pregnancy. It should be noted that both of the drugs are not recommended to be used in pregnancy but we may come across situations where the patient is already exposed to these drugs and not willing to abort pregnancy and this case adds value to the existing body of medical literature in such cases","PeriodicalId":300833,"journal":{"name":"International Journal of Pregnancy & Child Birth","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115383338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"SneakPeek snap: a painless microneedle-based pushbutton device for early fetal sex determination","authors":"Nina Hoang, Haley Milot, C. Jacob","doi":"10.15406/ipcb.2021.07.00232","DOIUrl":"https://doi.org/10.15406/ipcb.2021.07.00232","url":null,"abstract":"The advancement of prenatal DNA technology and growing demand for early fetal sex determination have created a need for a simple and easy-to-use blood collection device that eliminates the pain and difficulty individuals encounter when utilizing traditional methods of blood collection such as venipuncture or lancet fingerstick. In this study, Gateway Genomics, the leading provider of fetal sex testing, introduces “SneakPeek Snap”, a novel microneedle-based, self-administered blood collection device that simplifies at-home blood collection for fetal sex testing. Our data confirms that, compared to lancet finger sticks, the SneakPeek Snap device provides users several advantages including significant reduction in perceived pain, greater ease of use, a shorter sample collection time, and a dramatic reduction in risk of sample contamination. Notably, blood samples collected using the Snap device were shown to be highly accurate for fetal sex determination — with an accuracy greater than 99%","PeriodicalId":300833,"journal":{"name":"International Journal of Pregnancy & Child Birth","volume":"58 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116816953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Readiness for implementation of preconception care in Uganda; a review on the current policy, health system barriers, opportunities and way forward","authors":"I. Nathan, A. Nyabigambo, Agnes Kayego, P. Waiswa, Kele Moley, Salimah R. Walani","doi":"10.15406/ipcb.2021.07.00231","DOIUrl":"https://doi.org/10.15406/ipcb.2021.07.00231","url":null,"abstract":"Background: Uganda like other low-income countries, preconception health has received no attention. Communications in this article are derived from preliminary findings of an ongoing preconception baseline pilot in Luuka-a rural eastern district of Uganda. This is a phased study, including a desk review of literature and a short baseline pilot. Methods: The review followed the methodology of systematic reviews. Key electronic databases were searched including PUBMED/MEDLINE and google scholar. Also, reports from ministries/academic institution libraries and views from experts were done. English articles published post 2000, covering preconception care, barriers, facilitators and policies were included in the review. Out of 110 shortlisted abstracts, 28 were included. Studies were extracted onto structured formats and analysed using the narrative synthesis approach. Results: There exist unstructured preconception health and service guidelines in Uganda. Barriers to preconception service integration into the district’s health system include; lack of a clear policy, careworn health system and care seeker related factors. Opportunities for preconception service integration include; poor maternal and neonatal health indicators, positive change in health seeking behaviour, existence of a gap in the care continuum, functional VHT system to link the community to services, anticipated roll out of key family care practises by Ministry of Health Uganda, and improved access to radio & mobile phones. Conclusion: Formulation of clear preconception guidelines, testing health system integration approaches, stakeholders’ engagement, awareness creation and strengthening the supply side is recommended as a way forward","PeriodicalId":300833,"journal":{"name":"International Journal of Pregnancy & Child Birth","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116481934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of traditional birth attendants in providing pre and postnatal care to mothers in refugee camps: a case of Ifo Camp Dadaab Kenya","authors":"Teresa Mwoma, J. Gitome, Newton Kahumbi, Priscila Ndegwa, Muthoni Maina, J. Bagelman","doi":"10.15406/IPCB.2021.07.00229","DOIUrl":"https://doi.org/10.15406/IPCB.2021.07.00229","url":null,"abstract":"Access to skilled birth attendance is critical in improving maternal and newborn health. However, in low resource settings, rural and refugee camps, professionally trained staff are often in short supply hence women tend to rely on traditional birth attendants (TBAs) for delivery. Despite knowledge that a health care facility delivery is safer, many women from low resource environments continue to seek for the care of TBAs. In order to understand the care provided to refugee women during pregnancy and after birth, in a refugee camp, a study was conducted in Ifo Dadaab refugee camp in Kenya. The aim of this article therefore, is to document findings on participants’ perspectives on pre and post-natal care provided to women in refugee camps during pregnancy and after birth. This was a qualitative study conducted in Ifo refugee camp in Dadaab Kenya. Nine participants were purposively selected for the study to give their perspectives on the role of TBAs in providing caregiving support to refugee women during pregnancy and after birth. The participants included two married men, three traditional birth attendants, two Somali pregnant women and two refugee safe mothers. Data was collected through focus group discussions and interviews. The data was beefed up with feedback from dissemination of preliminary findings to stakeholders’ validation conference held at Kenyatta University. Findings revealed that TBAs play a critical role in supporting women during pregnancy and after birth. However, they are not able to attend to complications associated to delivery. Among the caring support cited include, guiding and counselling pregnant women, educating them on the importance of attending antenatal clinics, massaging women during labour, praying for the baby after birth, and escorting women to the health facilities to take their babies for immunization. It was also apparent that TBAs advise pregnant women on the herbs they should have in stock while pregnant. In addition, they advise women to breast feed their babies immediately after birth. While TBAs are able to assist un complicated births at home, it was apparent that it becomes challenging for them to provide support for women with complication during the birth process. In view of this, it will be more helpful for TBAs to be encouraged to guide and advise pregnant women to deliver in the health care facility, where they can escort them to get professional attention during birth","PeriodicalId":300833,"journal":{"name":"International Journal of Pregnancy & Child Birth","volume":"326 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132982273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Single vs. extended antibiotic for prevention of surgical infection in emergent cesarean delivery","authors":"David Nitrushwa, R. Ghebre, M. A. Unyuzimana, U. Magriples, M. Small, S. Rulisa","doi":"10.15406/IPCB.2021.07.00228","DOIUrl":"https://doi.org/10.15406/IPCB.2021.07.00228","url":null,"abstract":"Objective: Emergency Cesarean Section (ECS) improves maternal and neonatal outcomes but can be associated with complications including Surgical Site Infections (SSI). Prophylactic antibiotics reduce SSIs but inappropriate use increases antibiotic resistance. The study aim was to assess single versus multiple-dose antibiotic prophylaxis for SSI prevention in a limited-resource setting. Methods: All patients undergoing ECS in a rural district hospital were assessed for eligibility from 2015 to 2016. Participants were randomized, Group A received one dose of 2 g Ampicillin 15 to 60 minutes before skin incision and Group B received 2 g prior to skin incision with additional 1g every 8 hours over 72 hours. Participants were followed for 30 days, Demographic and clinical data were collected by chart review and patient phone interviews were performed on Days 3, 7, 15 and 30. Results: Three hundred and one participants were analyzed (147 in Group A; 154 in Group B). There were 8 surgical site infections in Group A and 4 in Group B (p=0.089). The overall prevalence of surgical site infections was lower than expected (4.00%). Most of SSIs cases were diagnosed on day 7 (66.6% of all cases of SSI) and only 22.2% of cases were diagnosed at discharge (day 3). Only 1 additional case was diagnosed at day 15. Conclusion: Compliance to infection control measures can reduce the rate of SSIs. There was no significant difference between the use of a single vs multiple doses of prophylactic antibiotics in our study but the SSI rate was low.","PeriodicalId":300833,"journal":{"name":"International Journal of Pregnancy & Child Birth","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133857539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Universal screening for sars-cov-2 in pregnant entered in an obstetrics hospitalization unit","authors":"María Pola Guillén, Elías Ortiz Molina, Fiamma García Sánchez, Valentin Rodrigo Alvaro, Elizabeth Gonzalez Prieto, Ana Pascual Pedreño","doi":"10.15406/IPCB.2021.07.00227","DOIUrl":"https://doi.org/10.15406/IPCB.2021.07.00227","url":null,"abstract":"Objective: Determine the strengths and weakness of asymptomatic screening for COVID-19 in pregnant women. Analyze the results an percentage of positives in asyntomatic pregnant women. Design: Descriptive retrospective observational study. Setting: Mancha-Centro Hospital (Spain). Population: Asymptomatic pregnant women that get in to the hospital. Methods: Between the 12th of April and 1th of June 2020, all the asymptomatic pregnancies were screened with diagnostic test for SARS-CoV-2. Data collection was done by reviewing the medical records. Main outcomes measures: Clinical characteristics, management, treatment, and obstetric and neonatal outcomes. Results: A total of 117 patients were routinely screened using serological tests in maternal blood and PCR in nasopharyngeal exudate to detect COVID-19 patients. Of the 117 patients screened, 24 (20.5%) were positive in at least one of the two tests used for screening, of which 19 (79%) were asymptomatic and 5 (21%) symptomatic. Conclusions: We recommend universal screening of all pregnant woman for COVID-19 during the pandemic because of the limits of the symptomatic screening seen in the actual literature and the importance of transmission between asymptomatics patients.","PeriodicalId":300833,"journal":{"name":"International Journal of Pregnancy & Child Birth","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134578925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Postnatal diagnosis of harlequin ichthyosis a case report","authors":"M. Ahmed, M. Mohamed, S. Abbas, Athar Mohammed, Nosiba Ibrahim Hammed Alyamani","doi":"10.15406/IPCB.2021.07.00224","DOIUrl":"https://doi.org/10.15406/IPCB.2021.07.00224","url":null,"abstract":"Objective: Ichthyoses are cornification disorders in which irregular epidermal separation and desquamation result in a faulty epidermal membrane. Harlequin ichthyosis (HI) was a rare and extreme type that led to neonatal death. It was caused by mutations in the ABCA12 gene, and the inheritance pattern is autosomal recessive. Case report: We present a case of HI that was diagnosed postnatally by clinical review. Extreme ectropion, eclabium, flattened nose, and primitive ears were discovered in the fetus. As a result of HI complications, the fetus died. Conclusion: The presence of HI was linked to a poor prognosis and a high mortality rate. Prenatal ultrasound and genetic analysis were critical for prenatal diagnosis of HI, but genetic modalities were not available and were prohibitively costly, despite their utility in providing appropriate prenatal therapy to families with HI babies. This case was recorded because of its rarity, as well as to draw attention to the connection between.","PeriodicalId":300833,"journal":{"name":"International Journal of Pregnancy & Child Birth","volume":"58 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126834824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nutrition status of pregnant women in selected internally displaced persons camp in Delta state, Nigeria","authors":"Enifome Akpotu, Faith C. Diorgu","doi":"10.15406/IPCB.2021.07.00223","DOIUrl":"https://doi.org/10.15406/IPCB.2021.07.00223","url":null,"abstract":"Introduction: The recent flood situation in Nigeria has contributed to the upsurge in the percentage of Internally Displace Persons particularly in the Delta State. Children and pregnant women are more venerable. Poor Nutritional status internally displaced person is a major occurrence. This has a serious implication for pregnant women in Nigeria. Assessing nutritional status of pregnant women will help in prioritizing need and intervention problems for internally displaced person, therefore this study will assess a Nutritional status of pregnant women in Selected internally displaced persons camps in Delta state Methods: A cross sectional study was conducted among pregnant women in four selected internally displaced person camps in Delta State, November 2019. A total of 99 pregnant women were randomly selected from each camp. A structured questionnaire was used to collect socio-demographic data from respondents, Body mass index and mid upper arm circumference with assessed result were compared with standard criteria for nutritional status. Data was clean and entered into SPSS Version 22. Descriptive statistics was used and inferential statistic, chi square and logistic regression was use for predicting variables after adjusting for confounders. Result: The mean body mass index of respondent was 23.5 (±3.9) which indicate a good nutritional health status, however 9.3% had poor nutritional status with BMI (>18.5). Also the mean distribution of MUAC was 27.5(±3.6) cm indicating good nutritional status of (<23cm), although 27.8% had poor nutritional status with (MUAC ≥23cm). chi square test, economic status (X2=9.794, (P=0.020<0.05), antenatal visit of at least twice in present ( X2=5.946, P=0.015) and pregnancy and present trimester (X2=12.939, P=0.002<0.05) were significantly associated with nutritional status of pregnant women. On regression analysis only ANC visit (OR= 3.134, Cl=1.226-8.013, p-value=0.17) and present trimester of pregnant women (OR=0.75,Cl=0.016-0.352, p-value=0.01) were significant Conclusion and recommendation: Poor nutritional status among pregnant women in this study is high, there is need to develop programs that focuses on educating mothers on the need of good nutrition in Nigeria.","PeriodicalId":300833,"journal":{"name":"International Journal of Pregnancy & Child Birth","volume":"93 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125686804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}