ACS Materials Au最新文献

{"title":"An Orthogonal Supramolecular Approach toward Protein Binding and Protein Sensing Using Dendrimers as Scaffolds for the Noncovalent Assembly of Binding and Sensing Groups","authors":"Azrah Aziz,&nbsp;Lance J. Twyman*,&nbsp;Amal Al Ageel,&nbsp;Ibrahim O. Althobaiti and Abdullah N. Alotaibi,&nbsp;","doi":"10.1021/acsmaterialsau.5c00049","DOIUrl":"https://doi.org/10.1021/acsmaterialsau.5c00049","url":null,"abstract":"<p >Inhibiting unwanted protein–protein interactions (PPIs) by targeting extensive protein binding surfaces presents a significant challenge. Macro-ligands offer a promising approach, but traditional covalent functionalization strategies often suffer from synthetic complexity, particularly in controlling the spatial arrangement of binding moieties. This study introduces a new method for macro-ligand design based on the noncovalent, modular self-assembly of functional units within an inert dendrimer scaffold. Although these units are embedded within the dendrimer in a random arrangement, they are mobile and free to move. As such, when a target protein is introduced, these binding units can undergo a self-organization process to optimize their spatial distribution and maximize cooperative interactions with the protein’s binding surface. This dynamic process is controlled by the protein, as it guides and controls the formation of its own optimized macromolecular ligand. When sensor units are combined and included in the assembly process, real-time monitoring and quantification of binding can be detected and quantified. This study details the synthetic methodology employed for the preparation of the component parts and their self-assembly into dendrimer complexes. Subsequent binding assays using cytochrome-c as the target protein, and associated dendrimer complexes, exhibited binding affinities in the nanomolar (nM) range.</p>","PeriodicalId":29798,"journal":{"name":"ACS Materials Au","volume":"5 5","pages":"849–857"},"PeriodicalIF":6.5,"publicationDate":"2025-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/pdf/10.1021/acsmaterialsau.5c00049","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145018386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improving Polymeric Structures with Hirshfeld Atom Refinement: A Study on MOFs and COFs","authors":"Magdalena Woińska*,&nbsp;Anna Makal,&nbsp;Paweł Grzymski-Ostręga,&nbsp;Michal L. Chodkiewicz and Krzysztof Wozniak*,&nbsp;","doi":"10.1021/acsmaterialsau.5c00076","DOIUrl":"https://doi.org/10.1021/acsmaterialsau.5c00076","url":null,"abstract":"<p >Many metal–organic frameworks (MOFs) and covalent organic frameworks (COFs) can form crystals amenable to single-crystal X-ray diffraction analysis. It makes them suitable for Hirshfeld atom refinement (HAR) which has a well-established advantage over the Independent Atom Model in terms of the determination of hydrogen atom positions in the case of molecular crystals. However, up until now, the application of HAR to crystals of polymeric compounds such as MOFs and COFs has not been thoroughly investigated. This study of X-ray data sets collected for 20 MOFs, COFs and other coordination polymers is designed to provide an extensive assessment of two different implementations of HAR with respect to hydrogen positions and refinement statistics, given varying data quality.</p>","PeriodicalId":29798,"journal":{"name":"ACS Materials Au","volume":"5 5","pages":"767–771"},"PeriodicalIF":6.5,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/pdf/10.1021/acsmaterialsau.5c00076","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145018312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Controlled Synthesis of Core–Shell–Shell Structured Sulvanite-Based Nanocomposites with Luminescent Property","authors":"Ha Na,&nbsp;Samuel Oyon,&nbsp;Linisha Biswal,&nbsp;Sahil Gasso,&nbsp;Daniela Radu and Cheng-Yu Lai*,&nbsp;","doi":"10.1021/acsmaterialsau.5c00079","DOIUrl":"https://doi.org/10.1021/acsmaterialsau.5c00079","url":null,"abstract":"<p >Despite growing interest in multifunctional nanomaterials for biomedical and sensing applications, there remains a notable scarcity of hybrid nanoparticles that integrate semiconducting, fluorescent, and biocompatible components into a single, tunable platform. The sulvanite Cu₃VS₄, a ternary chalcogenide with demonstrated near-infrared absorption and photothermal conversion properties, has been relatively underexplored compared to more conventional binary chalcogenides in such hybrid constructs. In this work, core–shell–shell structured Cu₃VS₄@SiO₂@Tb/GMP nanoparticles exhibiting green luminescence have been designed and fabricated. The multistep synthesis process involved Cu₃VS₄ synthesis and pretreatment followed by the addition of the silica shell, and last by simultaneous terbium (Tb) coordination and surface modification with guanosine monophosphate. The morphology, structure, and optical properties of the nanoparticles were systematically characterized using transmission electron microscopy, X-ray diffraction, Raman spectroscopy, Fourier transform infrared spectroscopy, and photoluminescence spectroscopy. Structural analysis confirmed the formation of well-defined spherical nanostructures with homogeneous dual-shell architecture and an average particle diameter of 50 nm. Upon excitation at 295 nm, the nanoparticles demonstrated intense green emission attributed to the characteristic electronic transitions of the Tb³⁺ ions. Furthermore, the incorporation of GMP enhanced the fluorescence stability of the nanoparticles, making them promising candidates for applications in bioimaging, optoelectronics, or sensing. These findings suggest that the developed nanoparticles hold significant potential for diverse applications, including bioimaging, optoelectronic devices, and fluorescence-based sensing platforms.</p>","PeriodicalId":29798,"journal":{"name":"ACS Materials Au","volume":"5 5","pages":"870–877"},"PeriodicalIF":6.5,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/pdf/10.1021/acsmaterialsau.5c00079","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145018309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lipid-Inspired Low Melting Ionic Liquids via Synergistic Cyclopropanation and Branching of Terpenoids","authors":"Muhammadiqboli Musozoda,&nbsp;Richard A. O’Brien,&nbsp;Zachary J. Metott,&nbsp;Raychell A. Jerdo,&nbsp;Christopher M. Butch,&nbsp;Matthias Zeller,&nbsp;Gregory R. Boyce*,&nbsp;Patrick C. Hillesheim* and Arsalan Mirjafari*,&nbsp;","doi":"10.1021/acsmaterialsau.5c00089","DOIUrl":"https://doi.org/10.1021/acsmaterialsau.5c00089","url":null,"abstract":"<p >Bacteria employ cyclopropane motifs as bioisosteres for unsaturations to modulate lipid bilayer fluidity and protect cellular membranes under environmental stress. Drawing inspiration from this biological strategy, we investigated how cyclopropanation impacts the thermophysical properties of lipid-inspired ionic liquids. We synthesized a series of imidazolium-based ionic liquids incorporating cyclopropanated derivatives of three renewable terpenoids: phytol, farnesol, and geraniol. Through an integrated approach combining property-driven design, thermophysical analysis, X-ray crystallography, and computational modeling, we systematically examined how these structural modifications influence quantitative structure–property relationships. Our findings demonstrate that ionic liquids with long alkyl appendages respond to side-chain modifications─particularly the synergistic combination of cyclopropanation and branching─in a manner that mimics homeoviscous adaptation in living organisms. The strategic incorporation of cyclopropyl moieties combined with chiral methyl branching produced dramatic melting point depressions, with phytol-derived ionic liquids achieving the lowest melting points reported to date for these bioinspired materials. This effectiveness results from positioning these structural elements within the symmetry-breaking region of alkyl chains, where they maximally disrupt molecular packing and enhance fluidity. X-ray crystallographic analysis of a cyclopropanated citronellyl-based ionic liquid revealed that the cyclopropyl ring induces significant conformational distortions that prevent efficient molecular organization. The use of terpenoids from the chiral pool as starting materials imparts inherent sustainability to these ILs. Enantiopure ILs can be synthesized from renewable feedstocks like phytol and citronellol while exploiting bioinspired structural design principles. This work provides new insights into IL structure–property relationships that both complement and extend previous discoveries, establishing a framework for the rational design of lipidic ionic liquid systems with enhanced fluidity and chemical stability from renewable resources.</p>","PeriodicalId":29798,"journal":{"name":"ACS Materials Au","volume":"5 5","pages":"878–885"},"PeriodicalIF":6.5,"publicationDate":"2025-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/pdf/10.1021/acsmaterialsau.5c00089","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145018308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multilayered Fabrication Containing Wind Turbine Blade Solid Wastes for High-Performance Composite Fibers","authors":"Varunkumar Thippanna,&nbsp;Arunachalam Ramanathan,&nbsp;Dhanush Patil,&nbsp;M. Taylor Sobczak,&nbsp;Taylor G. Theobald,&nbsp;Sri Vaishnavi Thummalapalli,&nbsp;Xiao Sun,&nbsp;Churan Yu,&nbsp;Ian Doran,&nbsp;Chao Sui,&nbsp;Joshua Were,&nbsp;Xianqiao Wang,&nbsp;Sui Yang,&nbsp;Xin Xu,&nbsp;Arunachala Nadar Mada Kannan,&nbsp;Amir Asadi,&nbsp;Ayman Nafady,&nbsp;Abdullah M. Al-Enizi,&nbsp;Mohammad K. Hassan and Kenan Song*,&nbsp;","doi":"10.1021/acsmaterialsau.5c00041","DOIUrl":"https://doi.org/10.1021/acsmaterialsau.5c00041","url":null,"abstract":"<p >The disposal of wind turbine blade (WTB) waste poses a significant environmental challenge due to its high volume and complex composition. This study introduces an innovative approach to address this issue by repurposing WTB-derived glass fibers (GF) into high-performance polyacrylonitrile (PAN)-GF composite fibers through a scalable dry-jet wet spinning and forced assembly process. By integrating alternating layers of PAN and PAN-GF, layer thickness was precisely controlled to the micrometer scale, ensuring enhanced GF dispersion and improved orientation through shear stress at layer interfaces. The individual layer thickness in the multilayered PAN-GF fibers decreased progressively with an increasing number of layers, with 32-layered fibers exhibiting comparatively thicker layers, while 256-layered fibers demonstrated significantly thinner layers. The effects of WTB-GF incorporation on the thermal and mechanical properties of PAN fibers were examined using tensile testing and thermogravimetric analysis (TGA). Using GF loadings of 1–4 wt %, the 256-layered composite fibers demonstrated remarkable mechanical improvements, with stiffness (modulus) increasing by 54.7% from 15.10 to 23.37 GPa and tensile strength rising by 27.2% from 521.71 to 663.66 MPa compared to pure PAN fibers. TGA results indicate that increasing the GF content leads to higher residual weight at 900 °C, reflecting enhanced thermal stability and greater char yield. The 256-layered 10PAN-4GF fibers showed the highest residual mass (41.23 wt %), highlighting the significant contribution of GF reinforcement to thermal stabilization. Heat treatment further transformed these precursor fibers into carbonized fibers (CF) with exceptional thermal stability and performance under extreme conditions. This process highlights a sustainable pathway for reusing WTB waste and producing advanced composite fibers, making them ideal candidates for demanding applications such as aerospace and space exploration.</p>","PeriodicalId":29798,"journal":{"name":"ACS Materials Au","volume":"5 5","pages":"809–822"},"PeriodicalIF":6.5,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/pdf/10.1021/acsmaterialsau.5c00041","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145018389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Introducing the Tutorial Manuscript Type at the ACS Au Community Journals","authors":"Squire J. Booker,&nbsp;Stephanie L. Brock,&nbsp;Xiangdong Li,&nbsp;Géraldine Masson,&nbsp;Sébastien Perrier,&nbsp;Vivek V. Ranade,&nbsp;Raymond E. Schaak,&nbsp;Gemma C. Solomon and Shelley D. Minteer*,&nbsp;","doi":"10.1021/acsmaterialsau.5c00088","DOIUrl":"https://doi.org/10.1021/acsmaterialsau.5c00088","url":null,"abstract":"","PeriodicalId":29798,"journal":{"name":"ACS Materials Au","volume":"5 5","pages":"743–744"},"PeriodicalIF":6.5,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/pdf/10.1021/acsmaterialsau.5c00088","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145018388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":29798,"journal":{"name":"ACS Materials Au","volume":"5 4","pages":"12260–12268 XXX-XXX"},"PeriodicalIF":5.7,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/pdf/10.1021/mgv005i004_1956312","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144579082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"","authors":"Jefferson Honorio Franco,&nbsp;João Victor Bonaldo,&nbsp;Shelley D. Minteer and Adalgisa R. De Andrade*,&nbsp;","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":29798,"journal":{"name":"ACS Materials Au","volume":"5 4","pages":"12260–12268 XXX-XXX"},"PeriodicalIF":5.7,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/pdf/10.1021/acsmaterialsau.5c00039","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144579080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"","authors":"Carlotta Seno,&nbsp;Christopher B. Whitehead,&nbsp;David E. Salazar Marcano,&nbsp;Ian Chaon and Jonathan De Roo*,&nbsp;","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":29798,"journal":{"name":"ACS Materials Au","volume":"5 4","pages":"12260–12268 XXX-XXX"},"PeriodicalIF":5.7,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/pdf/10.1021/acsmaterialsau.5c00032","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144579079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"","authors":"Jaya Baranwal,&nbsp; and ,&nbsp;Danila Merino*,&nbsp;","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":29798,"journal":{"name":"ACS Materials Au","volume":"5 4","pages":"12260–12268 XXX-XXX"},"PeriodicalIF":5.7,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/pdf/10.1021/acsmaterialsau.5c00023","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144579083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}