{"title":"Muscle Ultrasound in Clinical Neurology: Diagnostic Uses and Guidance of Botulinum Toxin Injection","authors":"U. Walter","doi":"10.31728/jnn.2023.00133","DOIUrl":"https://doi.org/10.31728/jnn.2023.00133","url":null,"abstract":"Muscle ultrasound (MUS) is increasingly used by neurologists, neuropediatricians, neurosurgeons, specialized radiologists and anaesthesiologists for the imaging-supported diagnosis of neuromuscular disorders. Especially, MUS is highly sensitive in detecting fasciculations in motor neuron diseases, and in revealing intensive care unit acquired weakness. Hereditary and inflammatory myopathies are associated with distinct patters of echo-intensity changes of affected muscles. Moreover, MUS can be used for guiding needle biopsy of muscle lesions, and for targeting intramuscular botulinum neurotoxin (BoNT) injection in neurological disorders with muscle hyperactivity. MUS-guidance of BoNT injection is especially recommendable in complex cervical dystonia, in task-related hand dystonia (writer’s cramp, musician dystonia), and in children and adolescents with cerebral palsy. Modern ultrasound technologies such as sono-elastography, tissue Doppler, and high-definition microvasculature imaging allow for novel diagnostic and therapeutic uses. Recently, an international expert group reported consensus guidelines for neuromuscular ultrasound training. The present review provides a concise overview of well-established diagnostic and therapeutic applications of MUS in clinical neurology, with specific focus at MUS for targeting intramuscular BoNT injections.","PeriodicalId":294068,"journal":{"name":"Journal of Neurosonology and Neuroimaging","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129153298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cerebral Venous Thrombosis Combined with Spontaneous Intracranial Hypotension: A Case Report and Review of the Literature","authors":"Jinyoung Oh, S. Han, S. Chung","doi":"10.31728/jnn.2023.00135","DOIUrl":"https://doi.org/10.31728/jnn.2023.00135","url":null,"abstract":"Several cases of cerebral venous thrombosis (CVT) due to spontaneous intracranial hypotension (SIH) have been reported, with an estimated occurrence rate of 1–2% among patients with decreased intracranial pressure. However, the causal relationship between SIH and CVT as a potential risk factor is not well understood. According to the Monro-Kellie principle, this is thought to be caused by compensatory expansion of the cerebral venous system, damage to the intravenous wall due to changes in cerebral buoyancy, or increased venous blood viscosity. Although anticoagulation therapy is typically the first choice of treatment for patients diagnosed with CVT, considering the potential risk of intracerebral hemorrhage in patients with CVT secondary to SIH is important. We report the case of a patient who developed CVT as a complication of SIH and discuss its mechanisms and treatment options. Early identification and appropriate treatment can lead to successful outcomes and the prevention of potential complications.","PeriodicalId":294068,"journal":{"name":"Journal of Neurosonology and Neuroimaging","volume":"66 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127120939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Y. Yoon, Doyeon Kook, Hye-Sun Choi, Jiyun Lee, Y. Jung
{"title":"Hemorrhagic Stroke and Blindness after Hyaluronic Acid/Polylactic Acid Filler Injection","authors":"Y. Yoon, Doyeon Kook, Hye-Sun Choi, Jiyun Lee, Y. Jung","doi":"10.31728/jnn.2023.00139","DOIUrl":"https://doi.org/10.31728/jnn.2023.00139","url":null,"abstract":"The number of people receiving facial filler injections is increasing as it is relatively safe than the other cosmetic procedures. However, complications of facial filler injection range from mild redness and inflammation to cerebral infarction. We report the case of a patient who was diagnosed with cerebral infarction and intracranial hemorrhage after facial filler injection. A 61-year-old male presented to the emergency department with ocular pain and visual loss in the left eye after filler injection into the glabella. Neurological examination revealed monocular blindness. Initial brain magnetic resonance imaging (MRI) revealed small, acute multifocal infarctions in the left frontal, parietal, and temporal lobes. Follow-up MRI revealed subarachnoid hemorrhages in the left frontal and parietal lobe. Follow-up brain computed tomography showed small intracerebral hemorrhage in the left frontal lobe. Clinicians must be aware that not only cerebral infarction, but intracranial hemorrhage could also be a potential adverse effect of the cosmetic filler injection in the face.","PeriodicalId":294068,"journal":{"name":"Journal of Neurosonology and Neuroimaging","volume":"72 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127113926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Diagnosis and Management of Two Cases of Diabetic Muscle Ischemia","authors":"Seolah Lee, S. Yeom, SengMuk Kang, Chan-Doo Jeong, Boyeon Yang, Hyung-Min Kwon","doi":"10.31728/jnn.2023.00136","DOIUrl":"https://doi.org/10.31728/jnn.2023.00136","url":null,"abstract":"Diabetic muscle ischemia (DMI) is a rare complication of diabetes mellitus that presents as excruciating leg pain. Owing to its rare occurrence, DMI is seldom recognized. Here, we present two cases of DMI with a view to promote prompt diagnosis, thereby avoiding the need for patients to undergo unnecessary examinations.","PeriodicalId":294068,"journal":{"name":"Journal of Neurosonology and Neuroimaging","volume":"71 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132954968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Transcranial Doppler Ultrasound Role for Patients with Traumatic Brain Injury","authors":"A. Razumovsky","doi":"10.31728/jnn.2023.00132","DOIUrl":"https://doi.org/10.31728/jnn.2023.00132","url":null,"abstract":"Neurologists, neurosurgeons, and neurointensivists, including military, have a large armamentarium of diagnostic and monitoring devices available to detect primary and secondary brain injury and guide therapy in patients with acute traumatic brain injury (TBI) to avoid cerebral ischemia due to the posttraumatic vasospasm (PTV) and intracranial hypertension (ICH). This review summarizes the advantages and the specific roles of transcranial Doppler (TCD) ultrasonography for patients with acute and longterm effects of TBI. In critical care setting numerous publications showed that TCD is predictive of angiographic PTV and onset of ICH. The post TBI status of cerebrovascular reactivity and cerebral hemodynamics also has important implications with regard to the treatment of long-term effects of mild TBI (mTBI). Today it is abundant evidence that TCD is an important tool for monitoring the natural course of acute moderate and severe TBI, for evaluating the effect of medical treatment or intervention, for forecasting, and for identifying high-risk patients for onset of cerebral ischemia after TBI. TCD makes good clinical and economic sense as it is a reliable, quantitative, non-invasive and non-expensive “biomarker” to the acute clinical manifestations of TBI. TCD clinical utilization holds promise for better detection, characterization, and monitoring of objective cerebral hemodynamics changes in symptomatic patients with TBI not readily apparent by standard CT or conventional MRI techniques. TCD utilization will improve the sensitivity of neuroimaging to subtle brain perturbations and combining these objective measures with careful clinical characterization of patients may facilitate better understanding of the neural bases and treatment of the signs and symptoms of TBI. This review summarizes the advantages and the specific roles of TCD ultrasonography for patients with acute and long-term effects of TBI.","PeriodicalId":294068,"journal":{"name":"Journal of Neurosonology and Neuroimaging","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116754395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Youngjoo Kim, Seondeuk Kim, Seung-Beom Kim, Hyung-Min Kwon
{"title":"Impact of Severe Cervical Foraminal Stenosis on Contralateral C7 Nerve Transfer Outcomes","authors":"Youngjoo Kim, Seondeuk Kim, Seung-Beom Kim, Hyung-Min Kwon","doi":"10.31728/jnn.2023.00137","DOIUrl":"https://doi.org/10.31728/jnn.2023.00137","url":null,"abstract":"This report presents the case of a 67-year-old male patient with severe bilateral C6/7 foraminal stenoses who underwent contralateral seventh cervical nerve (C7) transfer as a treatment for left spastic hemiparesis resulting from a right middle cerebral artery infarction. The initial postoperative results showed improved spasticity and motor function, but these gains plateaued and even receded, unlike other studies that noted progress at 10–18 months post-surgery. We hypothesized that the presence of C7 radiculopathy due to severe cervical foraminal stenosis may affect long-term outcomes after contralateral C7 transfer and serve as a contraindication for this surgery. These findings emphasize the importance of thoroughly assessing patients with cervical foraminal stenosis and the associated risk of radiculopathy before considering a contralateral C7 transfer. Further research is needed to assess the prevalence of cervical foraminal stenosis in patients undergoing contralateral C7 transfer and explore alternative surgical approaches or adjunctive treatments to optimize postoperative outcomes.","PeriodicalId":294068,"journal":{"name":"Journal of Neurosonology and Neuroimaging","volume":"94 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124895870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Psychogios, O. Kargiotis, A. Safouris, G. Magoufis, L. Palaiodimou, M. Papadopoulou, S. Spiliopoulos, G. Velonakis, Michail Mantatzis, T. Karapanayiotides, P. Mitsias, G. Tsivgoulis
{"title":"Advanced Imaging in the Current Era of Acute Reperfusion Therapies","authors":"K. Psychogios, O. Kargiotis, A. Safouris, G. Magoufis, L. Palaiodimou, M. Papadopoulou, S. Spiliopoulos, G. Velonakis, Michail Mantatzis, T. Karapanayiotides, P. Mitsias, G. Tsivgoulis","doi":"10.31728/jnn.2023.00134","DOIUrl":"https://doi.org/10.31728/jnn.2023.00134","url":null,"abstract":"Reperfusion of the ischemic brain parenchyma with intravenous thrombolysis and/or mechanical thrombectomy is the cornerstone of acute ischemic stroke treatment. A paradigm shift from “time is brain” to a more precision medicine approach now called “imaging is brain”, has taken place during the last decade. This transformation has been fueled by the progress in neuroimaging. Advanced Neuroimaging incorporates perfusion imaging in order to depict real-time cerebral perfusion disturbances and provide maps of the penumbra and ischemic core that will inform individualized clinical decisions. Advance neuroimaging has now a fundamental role in triaging patients that will receive reperfusion treatments beyond the conventional time windows of 4.5 hours for intravenous thrombolysis and 6 hours for mechanical thrombectomy. We provide a narrative review of all the pivotal observational studies and randomized-controlled clinical trials that supported the use of advance neuroimaging, as well as technical issues and pitfalls that may be useful for its implementation in routine clinical practice.","PeriodicalId":294068,"journal":{"name":"Journal of Neurosonology and Neuroimaging","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114505644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yeonggeun Choi, Ju-Hun Lee, Hong-Ki Song, J. Bae, Yerim Kim
{"title":"Pheochromocytoma-related Headache and Symptoms that Should Not be Overlooked: A Case Report","authors":"Yeonggeun Choi, Ju-Hun Lee, Hong-Ki Song, J. Bae, Yerim Kim","doi":"10.31728/jnn.2022.00124","DOIUrl":"https://doi.org/10.31728/jnn.2022.00124","url":null,"abstract":"When a patient complaining of headache comes to the hospital, the focus is usually on checking for neurological disorders. After these are excluded, functional headaches are usually thought of, and it is easy to overlook other causes. In the case presented here, a patient was hospitalized with a severe headache. There were no specific findings in either brain imaging or cerebrospinal fluid. The severe headache persisted, accompanied by excessive sweating. As the cause was unclear, chest and abdomen computed tomography was taken, where an adrenal gland mass was confirmed. With a diagnosis of pheochromocytoma, the patient improved with treatment. This triad of symptoms (headache, sweating, and palpitations) should raise suspicion of pheochromocytoma; however, most patients do not present with all three symptoms. Because of this, if headaches persist without other neurological symptoms, further evaluation should be performed to determine other possible causes such as pheochromocytoma.","PeriodicalId":294068,"journal":{"name":"Journal of Neurosonology and Neuroimaging","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124577062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"False Normalization of Ankle Brachial Index: A Case of Lower Extremity Peripheral Arterial Disease with Normal Ankle-Brachial Index","authors":"Minsoo Sung, Y. Jung, Kyung-Yul Lee","doi":"10.31728/jnn.2023.00138","DOIUrl":"https://doi.org/10.31728/jnn.2023.00138","url":null,"abstract":"Screening for lower extremity peripheral arterial disease (PAD) is essential in assessing a patient’s risk of cerebrovascular disorders. The ankle-brachial index (ABI) is widely used as a screening tool for PAD, but it can produce falsely normalized results due to factors like artery calcification and collateral vessels. We report a patient with normal ABI but confirmed lower extremity PAD through ultrasound and computed tomography (CT). This case shows the limitation of ABI for PAD diagnosis. Additional tests, such as CT or ultrasound, should be considered when PAD is suspected, even if the ABI is normal.","PeriodicalId":294068,"journal":{"name":"Journal of Neurosonology and Neuroimaging","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127818759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Baeseoup Song, H. Yoon, Sangil Park, S. Heo, D. Chang, H. Woo
{"title":"Mobile Thrombus with an Ulcerative Plaque Diagnosed Using Ultrasonography in a Patient with Nonstenotic Carotid Artery Disease","authors":"Baeseoup Song, H. Yoon, Sangil Park, S. Heo, D. Chang, H. Woo","doi":"10.31728/jnn.2022.00128","DOIUrl":"https://doi.org/10.31728/jnn.2022.00128","url":null,"abstract":"More than 50% relevant artery stenosis is regarded as significant and may be responsible for an ischemic lesion in the corresponding brain area. However, a lesion with less than 50% stenosis with carotid plaque is classified as an embolic stroke of an undetermined source and might be underestimated as a potential source of stroke. A 53-year-old woman with motor weakness of the left limb showed multiple scattered small infarct lesions in the right middle cerebral artery territory with less than 50% stenosis of the right carotid artery on magnetic resonance angiography. No embolic source was detected from cardiac assessments. Carotid duplex sonography showed a mobile thrombus and an ulcerative plaque in the right carotid artery, and these were confirmed by digital subtraction angiography. Our case report suggests that carotid duplex sonography can be useful in patients who have ischemic stroke with an embolic pattern without significant arterial stenosis.","PeriodicalId":294068,"journal":{"name":"Journal of Neurosonology and Neuroimaging","volume":"150 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123209457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}