{"title":"Front Matter: Volume 11900","authors":"","doi":"10.1117/12.2619377","DOIUrl":"https://doi.org/10.1117/12.2619377","url":null,"abstract":"","PeriodicalId":292524,"journal":{"name":"Optics in Health Care and Biomedical Optics XI","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124661752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Recent development of optical wavefront shaping towards robust and optimum optical focusing and stimulation at depths in biological tissue","authors":"Qi Zhao, Puxiang Lai","doi":"10.1117/12.2601990","DOIUrl":"https://doi.org/10.1117/12.2601990","url":null,"abstract":"","PeriodicalId":292524,"journal":{"name":"Optics in Health Care and Biomedical Optics XI","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125253986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Label-free multiphoton imaging to rapidly classify the early and late-stage tumor necrosis in invasive breast cancer","authors":"Yung-Hsiang Yi, Zhen Li, Yulan Liu, Zhijun Li, Zhong-hua Han, D. Kang, Gangqin Xi, Jiajia He, Lianhuang Li, Liqin Zheng, Jianxin Chen, Jianhua Chen","doi":"10.1117/12.2602584","DOIUrl":"https://doi.org/10.1117/12.2602584","url":null,"abstract":"Necrosis is a form of cell death which is histologically characterized by homogeneous clusters and sheets of dead cells. Although several studies have indicated that the presence of tumor necrosis in pathological specimens may provide adverse prognostic information in solid tumor, the mechanism of necrosis is still unclear. Based on two-photon excited fluorescence (TPEF) and second-harmonic generation (SHG), multiphoton microscopy (MPM) is commonly used to monitor the morphological changes of biological tissues. In this study, we performed MPM imaging of the breast tissue and found that MPM can be used to rapidly classify the early and late-stage tumor necrosis in invasive breast cancer according to the changes of intracellular proteins. It demonstrated that MPM may provide a new assistant tool for pathologists to quickly and effectively classify the early and late-stage tumor necrosis.","PeriodicalId":292524,"journal":{"name":"Optics in Health Care and Biomedical Optics XI","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128029720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Optical vortex microrheology of turbid viscoelastic tissue","authors":"Jiaxing Gong, Qi Li, Hui Zhang, Jing Wang","doi":"10.1117/12.2602200","DOIUrl":"https://doi.org/10.1117/12.2602200","url":null,"abstract":"","PeriodicalId":292524,"journal":{"name":"Optics in Health Care and Biomedical Optics XI","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114984127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Molecule delivery by photoporation mediated by gold nanoparticles","authors":"C. Yao","doi":"10.1117/12.2602420","DOIUrl":"https://doi.org/10.1117/12.2602420","url":null,"abstract":"","PeriodicalId":292524,"journal":{"name":"Optics in Health Care and Biomedical Optics XI","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128095144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Research on evaluation optical parameters of bone thermal injury during microwave ablation","authors":"Yangyang Liu, Lingcui Meng, Weitao Li","doi":"10.1117/12.2602595","DOIUrl":"https://doi.org/10.1117/12.2602595","url":null,"abstract":"Microwave hyperthermic tumor ablation has played an important role in the treatment of bone tumors because of its obvious curative effect, less side effects and fewer complications. However, the real-time thermal injury evaluation model of bone and related soft tissue during microwave ablation is still in exploration. In this paper, it proposes to study thermal injury evaluation optical parameters of bone tissue during microwave ablation. In the microwave ablation experiment, it studied the changes of tissue near-infrared spectrum and optical parameters (reduced scattering coefficient, slope factor, area factor) during specific microwave ablation conditions. It was found that some factors (slope(524-532) and slope(565-570)) changed significantly, correlated with microwave ablation time, which could be used as evaluation parameters of bone thermal injury. The chosen slope factors can well describe the features of bone during microwave ablation, and have the potential to be used in microwave ablation computer-aided design. The results lay a foundation for establishment of a real-time evaluation system of bone tissue during microwave ablation.","PeriodicalId":292524,"journal":{"name":"Optics in Health Care and Biomedical Optics XI","volume":"176 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123505148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Assessing blood coagulation dynamics using a portable optical device","authors":"Hui Zhang, Jiaxing Gong, Qi Li, Wenjian Lu, Yaowen Zhang, Jing Wang","doi":"10.1117/12.2602594","DOIUrl":"https://doi.org/10.1117/12.2602594","url":null,"abstract":"","PeriodicalId":292524,"journal":{"name":"Optics in Health Care and Biomedical Optics XI","volume":"126 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122982361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"In vivo monitoring the disfunction of blood brain barrier and microglia in diabetic mice","authors":"Shaojun Liu, Dong-yu Li, Tingting Yu, D. Zhu","doi":"10.1117/12.2600780","DOIUrl":"https://doi.org/10.1117/12.2600780","url":null,"abstract":"","PeriodicalId":292524,"journal":{"name":"Optics in Health Care and Biomedical Optics XI","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121324461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}