Research on evaluation optical parameters of bone thermal injury during microwave ablation

Microwave hyperthermic tumor ablation has played an important role in the treatment of bone tumors because of its obvious curative effect, less side effects and fewer complications. However, the real-time thermal injury evaluation model of bone and related soft tissue during microwave ablation is still in exploration. In this paper, it proposes to study thermal injury evaluation optical parameters of bone tissue during microwave ablation. In the microwave ablation experiment, it studied the changes of tissue near-infrared spectrum and optical parameters (reduced scattering coefficient, slope factor, area factor) during specific microwave ablation conditions. It was found that some factors (slope(524-532) and slope(565-570)) changed significantly, correlated with microwave ablation time, which could be used as evaluation parameters of bone thermal injury. The chosen slope factors can well describe the features of bone during microwave ablation, and have the potential to be used in microwave ablation computer-aided design. The results lay a foundation for establishment of a real-time evaluation system of bone tissue during microwave ablation.