02.01 - Acute critical care最新文献

COVID-19 pneumonia hospitalizations in different phases of the pandemic in the United States: patient characteristics and clinical outcomes 美国疫情不同阶段COVID-19肺炎住院情况:患者特征和临床结果

02.01 - Acute critical care Pub Date : 2023-03-09 DOI: 10.1183/23120541.lsc-2023.39

E. Mozaffari, A. Kalil, A. Chandak, H. Jiang, R. Gottlieb, E. Lee, C. Der-Torossian, S. Hollemeersch, M. Thrun, C. Chima-Melton

引用次数: 0

C3a and C5b-9 levels differentially predict COVID-19 severity and mortality. C3a和C5b-9水平预测COVID-19严重程度和死亡率存在差异。

02.01 - Acute critical care Pub Date : 2022-09-04 DOI: 10.1183/13993003.congress-2022.2093

M. Detsika, E. Diamanti, K. Ampelakiotou, E. Jahaj, S. Tsipilis, N. Athanasiou, A. Zacharis, I. Dimopoulou, S. Orfanos, A. Tsirogianni, A. Kotanidou

引用次数: 0

Improved atelectasis and lung homogeneity with diaphragm neurostimulation during mechanical ventilation in pigs with ARDS 机械通气期间膈神经刺激改善ARDS猪肺不张和肺均匀性

02.01 - Acute critical care Pub Date : 2022-09-04 DOI: 10.1183/13993003.congress-2022.1023

E. Rohrs, T. Bassi, K. Fernandez, J. Wittmann, M. Nicholas, M. Ornowska, M. Gani, S. Reynolds

引用次数: 0

STUMBL score for emergency department safe discharge of patients with minor blunt thoracic trauma STUMBL评分对轻度钝性胸外伤患者急诊室安全出院的影响

02.01 - Acute critical care Pub Date : 2022-09-04 DOI: 10.1183/13993003.congress-2022.1628

J. Giamello, G. Martini, D. Prato, M. Santoro, Y. Arese, L. Bertolaccini, R. Melchio, C. Battle, T. Driscoll, A. Bono, A. Poggi, A. Bruno, A. Falcetta, A. Sciolla, C. Fulcheri, D. Caruso, G. Lauria

引用次数: 1

A pilot trial for ozanimod therapy in hospitalized COVID-19 patients ozanimod治疗住院COVID-19患者的试点试验

02.01 - Acute critical care Pub Date : 2022-09-04 DOI: 10.1183/13993003.congress-2022.520

D. Marsolais, N. Châteauvert, P. Blais-Lecours, P. Rola, T. Nguyen, F. Lellouche

{"title":"A pilot trial for ozanimod therapy in hospitalized COVID-19 patients","authors":"D. Marsolais, N. Châteauvert, P. Blais-Lecours, P. Rola, T. Nguyen, F. Lellouche","doi":"10.1183/13993003.congress-2022.520","DOIUrl":"https://doi.org/10.1183/13993003.congress-2022.520","url":null,"abstract":"Background: Sphingosine-1-phosphate (S1P) receptor ligands reduce lung damage and endothelial activation in models of virus-induced pneumonia. Feasibility of initiating S1P receptor ligand therapy during pneumonia needs confirmation. Objective(s): Evaluate safety/efficacy outcomes of ozanimod therapy in COVID-19 patients. Method(s): In a prospective multicentric open-label pilot trial, adults with COVID-19 requiring O were recruited (3 Canadian centres, starting Sept. 2020). Patients were randomized to standard of care (SOC) or SOC + ozanimod (per os). Modified WHO-adapted 6-points ordinal scale for clinical improvement was computed daily and adverse events were recorded. Result(s): As of Jan. 2022, 41 patients (out of 48) were enrolled and 18 received ozanimod. Stratification at randomization balanced groups for risk factors of poor outcome and initial O2 requirement. No serious drug reaction was reported. Asymptomatic bradycardia occurred with ozanimod. So far, 36 patients completed the study-ending phone call (day 90). Ordinal scale-related outcomes are shown in Table 1. Since enrollment is ongoing, data is shown for the whole cohort. Conclusion(s): This small scale trial provides the very first evidence supporting the possibility of initiating S1P receptor ligand therapy during active COVID-19 pneumonia.","PeriodicalId":289883,"journal":{"name":"02.01 - Acute critical care","volume":"75 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117000473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Awake Prone Positioning in Acute Hypoxemic Respiratory Failure from COVID-19: A Randomized Clinical Trial 醒着俯卧位治疗COVID-19急性低氧性呼吸衰竭:一项随机临床试验

02.01 - Acute critical care Pub Date : 2022-09-04 DOI: 10.1183/13993003.congress-2022.3107

W. Alhazzani, K. Parhar, J. Weatherald, Z. Al Duhailib, M. Alshahrani, A. Al-Fares, S. Buabbas, S. Cherian, L. Munshi, E. Fan, F. Al-Hameed, J. Chalabi, A. Rahmatullah, E. Duan, J. Tsang, K. Lewis, F. Lauzier, J. Centofanti, B. Rochwerg, S. Culgin, K. Nelson, S. Abdukahil, K. Fiest, H. Stelfox, H. Tlayjeh, M. Meade, D. Perri, K. Solverson, D. Niven, R. Lim, M. Møller, E. Belley-Côté, L. Thabane, H. Tamim, D. Cook, Y. Arabi

引用次数: 0

To assess the diagnostic and prognostic ability of CXRs in COVID-19 pneumonitis 评价cxr对COVID-19肺炎的诊断和预后能力

02.01 - Acute critical care Pub Date : 2022-09-04 DOI: 10.1183/13993003.congress-2022.4254

H. Ahmad, S. Soman, R. Varghese, K. Dewan, R. Chapman, J. Tong, R. Kumari, U. Ekeowa, R. Ragatha, P. Russell, S. Kuckreja, M. Long, M. Anwar

引用次数: 0

Impact of combined non-invasive support strategies use during acute respiratory failure due to COVID-19. COVID-19急性呼吸衰竭期间联合使用无创支持策略的影响

02.01 - Acute critical care Pub Date : 2022-09-04 DOI: 10.1183/13993003.congress-2022.4043

J. Marín Corral, F. Parrilla, M. Restrepo, S. Pascual-Guardia, A. Rodríguez, J. C. Ballesteros, S. Sancho, L. Socias, E. Diaz, A. Albaya-Moreno, J. Masclans

{"title":"Impact of combined non-invasive support strategies use during acute respiratory failure due to COVID-19.","authors":"J. Marín Corral, F. Parrilla, M. Restrepo, S. Pascual-Guardia, A. Rodríguez, J. C. Ballesteros, S. Sancho, L. Socias, E. Diaz, A. Albaya-Moreno, J. Masclans","doi":"10.1183/13993003.congress-2022.4043","DOIUrl":"https://doi.org/10.1183/13993003.congress-2022.4043","url":null,"abstract":"Objectives: To evaluate the impact of combined non-invasive support strategies in critically ill COVID-19 patients [high-flow nasal cannula (HFNC), non-invasive ventilation (NIV) or both]. Method(s): Prospective observational multicenter study in 73 Spanish ICU with data obtained from the SEMICYUC registry. All confirmed COVID-19 patients admitted due to respiratory failure were included. They were classified according to the ventilatory strategy used on admission and subsequently according to success, failure, or strategy change. Demographic data, comorbidities, severity at admission, respiratory, biomarkers, failure, length of stay and mortality were evaluated. Result(s): We analyzed 3,889 patients, 33% receiving HFNC, and 11% NIV at ICU admission. NIV group compared to HFNC were more severely ill with more shock on admission. When NIV was received as a first-choice higher failure rates and mortality were shown vs HFNC (68% vs 61%, p=0.016 and 27% vs 20%, p=0.003). Among patients who initially received HFNC, 57% failed and 7.4% switched to NIV, with no change in mortality. Among patients who were switched to NIV, 66% failed presenting a higher mortality trend than the intubated patients after the HFNC starting (40% vs 30%, p=0.098). Among patients who initially received NIV, 60% failed and 20% switched to HFNC. Patients in whom NIV was switched to HFNC, had lower mortality than patients who initially failed (18% vs 40%, p<0.001). Among patients who were switched to HFNC, 43% failed, presenting the same mortality as the intubated patients after the NIV starting (38% vs 38%, p=0.934). Conclusion(s): Patients receiving NIV at admission have worse outcomes than those receiving HFNC. Changing the strategy in patients who received HFNC as a first choice without success can worsen the prognosis.","PeriodicalId":289883,"journal":{"name":"02.01 - Acute critical care","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128062644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ventilator alarms that received no intervention:an analysis of ventilator alarm relationship in intensive care unit 未干预的呼吸机报警:重症监护病房呼吸机报警关系分析

02.01 - Acute critical care Pub Date : 2022-09-04 DOI: 10.1183/13993003.congress-2022.1240

C. Yujen, C. Shuhua, H. Yaochuan

引用次数: 0

Higher Crystalloids Volumes Predict Adverse Outcomes in Emergency Department Patients with Blunt Thoracic Trauma 更高的晶体体积预测急诊科钝性胸部创伤患者的不良结局

02.01 - Acute critical care Pub Date : 2022-09-04 DOI: 10.1183/13993003.congress-2022.1634

G. Martini, J. Giamello, P. Crida, Y. Arese, L. Bertolaccini, S. Abram, E. Basile, E. Bernardi, F. Morra, F. Corsini, F. Tosello, G. Sobrero, G. Greco, L. Barutta, M. Bironzo, G. Lauria

引用次数: 0