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B62. ASTHMA MECHANISMS最新文献

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Development of an Epithelial-Derived Airflow Obstruction Gene Expression Signature Using Systems Approaches 利用系统方法开发上皮来源的气流阻塞基因表达特征
B62. ASTHMA MECHANISMS Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3794
S. Roberts, M. Richardson, T. Hinks, P. Howarth, P. Bradding, S. Wenzel, S. Siddiqui
{"title":"Development of an Epithelial-Derived Airflow Obstruction Gene Expression Signature Using Systems Approaches","authors":"S. Roberts, M. Richardson, T. Hinks, P. Howarth, P. Bradding, S. Wenzel, S. Siddiqui","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3794","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3794","url":null,"abstract":"","PeriodicalId":287855,"journal":{"name":"B62. ASTHMA MECHANISMS","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125161179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Up-Regulation of Paraoxonase 2 in Human Bronchial Epithelial Cells 对氧磷酶2在人支气管上皮细胞中的上调
B62. ASTHMA MECHANISMS Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3829
D. Winnica, Sunita Sharma, L. Que, S. Ye, V. Smith, M. Cruse, N. Perez, F. Holguin
{"title":"Up-Regulation of Paraoxonase 2 in Human Bronchial Epithelial Cells","authors":"D. Winnica, Sunita Sharma, L. Que, S. Ye, V. Smith, M. Cruse, N. Perez, F. Holguin","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3829","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3829","url":null,"abstract":"","PeriodicalId":287855,"journal":{"name":"B62. ASTHMA MECHANISMS","volume":"118 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116448354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sex-Dependent Effect of TRPM8 rs10166942 Polymorphism on Cold-Induced Airway Hyperresponsiveness in Asthma TRPM8 rs10166942多态性对哮喘患者冷致气道高反应性的性别依赖性影响
B62. ASTHMA MECHANISMS Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3823
Denis Naumov, O. Kotova, D. Gassan, A. Prikhodko, V. Kolosov
{"title":"Sex-Dependent Effect of TRPM8 rs10166942 Polymorphism on Cold-Induced Airway Hyperresponsiveness in Asthma","authors":"Denis Naumov, O. Kotova, D. Gassan, A. Prikhodko, V. Kolosov","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3823","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3823","url":null,"abstract":"","PeriodicalId":287855,"journal":{"name":"B62. ASTHMA MECHANISMS","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129610691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Associations Between Arginine Metabolism Related Metabolites and Clinical Outcomes-A Longitudinal Metabolomic Study 精氨酸代谢相关代谢物与临床结果的关系——一项纵向代谢组学研究
B62. ASTHMA MECHANISMS Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3793
S. Liao, A. Linderholm, Megan Showalter, L. Franzi, O. Fiehn, A. Zeki, N. Kenyon
{"title":"Associations Between Arginine Metabolism Related Metabolites and Clinical Outcomes-A Longitudinal Metabolomic Study","authors":"S. Liao, A. Linderholm, Megan Showalter, L. Franzi, O. Fiehn, A. Zeki, N. Kenyon","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3793","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3793","url":null,"abstract":"","PeriodicalId":287855,"journal":{"name":"B62. ASTHMA MECHANISMS","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129251795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Decrease of Mitochondrial Biogenesis Contributes Airway Epithelial Barrier Dysfunction in Asthma 哮喘患者气道上皮屏障功能障碍与线粒体生物发生减少有关
B62. ASTHMA MECHANISMS Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3803
T. Saito, T. Ichikawa, N. Fujino, T. Numakura, Y. Sasaki, K. Itakura, M. Yamada, H. Sugiura, M. Ichinose
{"title":"The Decrease of Mitochondrial Biogenesis Contributes Airway Epithelial Barrier Dysfunction in Asthma","authors":"T. Saito, T. Ichikawa, N. Fujino, T. Numakura, Y. Sasaki, K. Itakura, M. Yamada, H. Sugiura, M. Ichinose","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3803","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3803","url":null,"abstract":"","PeriodicalId":287855,"journal":{"name":"B62. ASTHMA MECHANISMS","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121596548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
sST2/IL-33 Balance Regulates Neutrophil-Related Cytokine Release in the Human Airways sST2/IL-33平衡调节人气道中性粒细胞相关细胞因子释放
B62. ASTHMA MECHANISMS Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3807
Masato Watanabe, Mitsuru Sada, Keitaro Nakamoto, Toshiya Inui, Yukari Ogawa, Masaki Tamura, T. Yokoyama, K. Honda, T. Saraya, D. Kurai, H. Ishii, H. Takizawa
{"title":"sST2/IL-33 Balance Regulates Neutrophil-Related Cytokine Release in the Human Airways","authors":"Masato Watanabe, Mitsuru Sada, Keitaro Nakamoto, Toshiya Inui, Yukari Ogawa, Masaki Tamura, T. Yokoyama, K. Honda, T. Saraya, D. Kurai, H. Ishii, H. Takizawa","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3807","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3807","url":null,"abstract":"","PeriodicalId":287855,"journal":{"name":"B62. ASTHMA MECHANISMS","volume":"188 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115105111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Functional Translation of IL33 Locus Polymorphisms Into Altered Epithelial Cell Function Underlying Asthma IL33基因座多态性对哮喘上皮细胞功能改变的功能翻译
B62. ASTHMA MECHANISMS Pub Date : 2019-05-01 DOI: 10.1164/AJRCCM-CONFERENCE.2019.199.1_MEETINGABSTRACTS.A3800
M. Ketelaar, M. Portelli, F. N. Dijk, A. Faiz, N. Shrine, J. Hankinson, S. Bhaker, A. Henry, C. Billington, D. Shaw, S. Johnson, A. Benest, Z. Pogson, A. Fogarty, T. McKeever, A. Singapuri, L. Heaney, A. Mansur, R. Gaudhuri, N. Thomson, J. Holloway, G. Lockett, P. Howarth, R. Niven, A. Simpson, M. Tobin, D. Postma, I. Hall, L. Wain, C. Brightling, M. Obeidat, D. Sin, M. Berge, G. Koppelman, I. Sayers, M. Nawijn
{"title":"Functional Translation of IL33 Locus Polymorphisms Into Altered Epithelial Cell Function Underlying Asthma","authors":"M. Ketelaar, M. Portelli, F. N. Dijk, A. Faiz, N. Shrine, J. Hankinson, S. Bhaker, A. Henry, C. Billington, D. Shaw, S. Johnson, A. Benest, Z. Pogson, A. Fogarty, T. McKeever, A. Singapuri, L. Heaney, A. Mansur, R. Gaudhuri, N. Thomson, J. Holloway, G. Lockett, P. Howarth, R. Niven, A. Simpson, M. Tobin, D. Postma, I. Hall, L. Wain, C. Brightling, M. Obeidat, D. Sin, M. Berge, G. Koppelman, I. Sayers, M. Nawijn","doi":"10.1164/AJRCCM-CONFERENCE.2019.199.1_MEETINGABSTRACTS.A3800","DOIUrl":"https://doi.org/10.1164/AJRCCM-CONFERENCE.2019.199.1_MEETINGABSTRACTS.A3800","url":null,"abstract":"","PeriodicalId":287855,"journal":{"name":"B62. ASTHMA MECHANISMS","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129932794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of the Mechanism of Exercise Induced Bronchoconstriction in Murine Model 运动致小鼠支气管收缩的机制分析
B62. ASTHMA MECHANISMS Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3830
H. Ueno, T. Koya, K. Tsukioka, H. Takeuchi, Masahito Hayashi, T. Hasegawa, E. Suzuki, T. Kikuchi
{"title":"Analysis of the Mechanism of Exercise Induced Bronchoconstriction in Murine Model","authors":"H. Ueno, T. Koya, K. Tsukioka, H. Takeuchi, Masahito Hayashi, T. Hasegawa, E. Suzuki, T. Kikuchi","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3830","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3830","url":null,"abstract":"","PeriodicalId":287855,"journal":{"name":"B62. ASTHMA MECHANISMS","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129207099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Free Fatty Acid Receptor 1 (FFAR1) Agonist GW9508 Attenuates Excitation-Contraction Coupling in Human Airway Smooth Muscle (HASM) Cells 游离脂肪酸受体1 (FFAR1)激动剂GW9508减弱人气道平滑肌(HASM)细胞的兴奋-收缩偶联
B62. ASTHMA MECHANISMS Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3804
J. Jude, S. Xu, A. Schwab, N. Karmacharya, G. Cao, W. Jester, R. Panettieri
{"title":"Free Fatty Acid Receptor 1 (FFAR1) Agonist GW9508 Attenuates Excitation-Contraction Coupling in Human Airway Smooth Muscle (HASM) Cells","authors":"J. Jude, S. Xu, A. Schwab, N. Karmacharya, G. Cao, W. Jester, R. Panettieri","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3804","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3804","url":null,"abstract":"","PeriodicalId":287855,"journal":{"name":"B62. ASTHMA MECHANISMS","volume":"38 10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130086653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Identification of Sub-Sets of Viral Bronchiolitis Based on Clinical Phenotyping, Quantitative Lung Imaging, Respiratory Outcomes and Airway Immune Responses 基于临床表型、定量肺成像、呼吸结局和气道免疫反应的病毒性细支气管炎亚群鉴定
B62. ASTHMA MECHANISMS Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3799
M. Morr, K. Salka, Geovanny F. Perez, C. Rodríguez‐Martínez, J. A. Castro-Rodriguez, G. Nino
{"title":"Identification of Sub-Sets of Viral Bronchiolitis Based on Clinical Phenotyping, Quantitative Lung Imaging, Respiratory Outcomes and Airway Immune Responses","authors":"M. Morr, K. Salka, Geovanny F. Perez, C. Rodríguez‐Martínez, J. A. Castro-Rodriguez, G. Nino","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3799","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3799","url":null,"abstract":"","PeriodicalId":287855,"journal":{"name":"B62. ASTHMA MECHANISMS","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122271993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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