The Journal of ECTPub Date : 2017-09-01DOI: 10.1097/YCT.0000000000000396
E. Shao, Rachael L Moore, J. Linnane
{"title":"Rivaroxaban for Treatment of Pulmonary Embolism While Receiving Electroconvulsive Therapy.","authors":"E. Shao, Rachael L Moore, J. Linnane","doi":"10.1097/YCT.0000000000000396","DOIUrl":"https://doi.org/10.1097/YCT.0000000000000396","url":null,"abstract":"","PeriodicalId":287576,"journal":{"name":"The Journal of ECT","volume":"33 3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129529085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The Journal of ECTPub Date : 2017-09-01DOI: 10.1097/YCT.0000000000000393
Puneet Narang, F. Ianovich, S. Sarai, S. Lippmann
{"title":"Benefits of Dexmedetomidine in Management of Post-ECT Agitation","authors":"Puneet Narang, F. Ianovich, S. Sarai, S. Lippmann","doi":"10.1097/YCT.0000000000000393","DOIUrl":"https://doi.org/10.1097/YCT.0000000000000393","url":null,"abstract":"Abstract Electroconvulsive therapy (ECT) is an intervention for patients with a variety of psychiatric conditions. Occasionally, people exhibit dangerous degrees of agitation after this treatment, and some do not respond well to conventional pharmacotherapies. Dexmedetomidine is a central &agr;-2 agonist that can induce significantly calmative effects in persons with post-ECT agitation. The indication for it is in calming individuals with acute and/or recurrent posttreatment agitation. Dexmedetomidine is safe and effective when infused just before, or postictally, at ECT sessions.","PeriodicalId":287576,"journal":{"name":"The Journal of ECT","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132119832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The Journal of ECTPub Date : 2017-09-01DOI: 10.1097/YCT.0000000000000391
A. O’Neill-Kerr, Anhar Yassin, S. Rogers, J. Cornish
{"title":"Switching From Age-Based Stimulus Dosing to Dose Titration Protocols in Electroconvulsive Therapy: Empirical Evidence for Better Patient Outcomes With Lower Peak and Cumulative Energy Doses","authors":"A. O’Neill-Kerr, Anhar Yassin, S. Rogers, J. Cornish","doi":"10.1097/YCT.0000000000000391","DOIUrl":"https://doi.org/10.1097/YCT.0000000000000391","url":null,"abstract":"Objective The aim of this study was to test the proposition that adoption of a dose titration protocol may be associated with better patient outcomes, at lower treatment dose, and with comparable cumulative dose to that in patients treated using an age-based stimulus dosing protocol. Methods This was an analysis of data assembled from archived records and based on cohorts of patients treated respectively on an age-based stimulus dosing protocol and on a dose titration protocol in the National Health Service in England. Results We demonstrated a significantly better response in the patient cohort treated with dose titration than with age-based stimulus dosing. Peak doses were less and the total cumulative dose was less in the dose titration group than in the age-based stimulus dosing group. Conclusions Our findings are consistent with superior outcomes in patients treated using a dose titration protocol when compared with age-based stimulus dosing in a similar cohort of patients.","PeriodicalId":287576,"journal":{"name":"The Journal of ECT","volume":"61 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131126165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The Journal of ECTPub Date : 2017-09-01DOI: 10.1097/YCT.0000000000000387
C. Theleritis, P. Sakkas, T. Paparrigopoulos, S. Vitoratou, C. Tzavara, S. Bonaccorso, A. Politis, C. Soldatos, Costantin Psarros
{"title":"Two Versus One High-Frequency Repetitive Transcranial Magnetic Stimulation Session per Day for Treatment-Resistant Depression: A Randomized Sham-Controlled Trial","authors":"C. Theleritis, P. Sakkas, T. Paparrigopoulos, S. Vitoratou, C. Tzavara, S. Bonaccorso, A. Politis, C. Soldatos, Costantin Psarros","doi":"10.1097/YCT.0000000000000387","DOIUrl":"https://doi.org/10.1097/YCT.0000000000000387","url":null,"abstract":"Objectives High-frequency repetitive transcranial magnetic stimulation (HF-rTMS) has proven antidepressant effects, but the optimal frequency of sessions remains unclear. Methods We conducted a 3-week, sham-controlled trial to assess the antidepressant efficacy of 1 active HF-rTMS session per day (A1 group) compared with 2 per day (A2 group) and equivalent sham sessions (once a day, S1 group; twice a day, S2 group) in patients with treatment-resistant major depression with a subsequent 2-week follow-up period. One hundred seventy-seven patients were screened, of whom 105 met eligibility criteria and 98 consented and were randomized. The HF-rTMS (20 Hz) was targeted to the left prefrontal cortex in sessions of approximately 40 trains (2 seconds each) at 100% resting motor threshold with an intertrain interval of 1 minute. Treatment response was defined as a 50% or greater decrease in the Hamilton Depression Rating Scale (HDRS) score and/or Clinician Global Impressions-Severity of Illness (CGI-S) score of 3 or less. Remission was defined as HDRS score less than 8 and/or CGI-S score of 2 or less. Results Practically none of the subjects in either sham groups achieved remission. Increased odds of remission were present for CGI-S by stimulating twice rather than once per day (odds ratio [OR] = 1.5, P = 0.018), whereas there was a marginal result for HDRS (OR = 3.9, P = 0.066). Patients who had lower baseline HDRS (OR = 0.75, P = 0.014) and CGI-S scores (OR = 0.18, P = 0.001) were more likely to achieve remission. Conclusions Twice per day active HF-rTMS might be more effective than once per day active HF-rTMS or sham stimulation.","PeriodicalId":287576,"journal":{"name":"The Journal of ECT","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122130575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The Journal of ECTPub Date : 2017-09-01DOI: 10.1097/YCT.0000000000000374
Nicky Buley, E. Copland, Sophie Hodge, R. Chaplin
{"title":"A Further Decrease in the Rates of Administration of Electroconvulsive Therapy in England","authors":"Nicky Buley, E. Copland, Sophie Hodge, R. Chaplin","doi":"10.1097/YCT.0000000000000374","DOIUrl":"https://doi.org/10.1097/YCT.0000000000000374","url":null,"abstract":"Objectives Electroconvulsive therapy (ECT) is an effective treatment of major depression, and there have been consistent improvements in the administration of ECT in the past decade. However, studies have reported a steady decline in the rates of use of ECT in the United Kingdom and Ireland. Despite this, there has been no consistent record of how much ECT is being given or to whom it is given, for more than 20 years. The purpose of this study is to estimate the change in frequency of ECT use, the length of courses, patient demographics, and clinical outcomes between 2006 and 2 periods of 2012/2013 and 2014/2015. Methods In 2012/2013, clinics were asked to complete an online survey giving details of every patient who started a course of ECT between April 1, 2012, and March 31, 2013. This was repeated for the same period in 2014/2015. Results There continues to be a striking decline in the number of courses of ECT prescribed. Course length has increased. Women are twice as likely to be prescribed ECT as men. Modal age is 60 to 80 years, and the most common diagnosis is depression. Most courses were rated as clinically effective, especially for people with severe illnesses. Maintenance ECT is used at half the clinics surveyed. Conclusions The use of ECT in England continues to decline. The reasons for this are unclear and need investigation.","PeriodicalId":287576,"journal":{"name":"The Journal of ECT","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123331475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The Journal of ECTPub Date : 2017-06-01DOI: 10.1097/YCT.0000000000000373
Timothy E. Lau, Prakash Kishor Babani, L. McMurray
{"title":"The Treatment of Disruptive Vocalization in Dementia (Behavioral and Psychological Symptoms of Dementia) With Electroconvulsive Therapy: A Case Series","authors":"Timothy E. Lau, Prakash Kishor Babani, L. McMurray","doi":"10.1097/YCT.0000000000000373","DOIUrl":"https://doi.org/10.1097/YCT.0000000000000373","url":null,"abstract":"Objective There is emerging evidence that electroconvulsive therapy (ECT) can help with the behavioral and psychological symptoms of dementia. One of the most distressing behavioral symptoms of dementia is disruptive vocalization. Previous small case series have suggested that antidepressants and ECT can be beneficial for this distressing condition. The aim of this study was to describe the successful use of ECT in treating 5 patients with disruptive vocalization. Methods A retrospective chart review of 5 patients with dementia of mixed etiologies was conducted comparing pretreatment and posttreatment scores on the Cohen-Mansfield Agitation Inventory. All 5 patients had unsuccessful treatments with nonpharmacological methods and pharmacotherapy including antidepressants. Results After completion of a series of ECT, the mean verbal agitation score decreased from 6.8 (95% confidence interval, 6.3–7.3) to 2.3 (95% confidence interval, 1.3–3.3), with both clinical and statistical significance (P < 0.001). Conclusions Although further research is needed, these findings support considering the use of ECT for disruptive vocalization in dementia.","PeriodicalId":287576,"journal":{"name":"The Journal of ECT","volume":"74 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122421875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The Journal of ECTPub Date : 2017-06-01DOI: 10.1097/YCT.0000000000000358
Chun-Jen Huang, Yu-hui Huang, Ching-Hua Lin
{"title":"Factors Related to the Changes in Quality of Life for Patients With Depression After an Acute Course of Electroconvulsive Therapy","authors":"Chun-Jen Huang, Yu-hui Huang, Ching-Hua Lin","doi":"10.1097/YCT.0000000000000358","DOIUrl":"https://doi.org/10.1097/YCT.0000000000000358","url":null,"abstract":"Objective The aim of this study was to examine the effect of electroconvulsive therapy (ECT) on quality of life (QOL), depressive symptoms, and functioning for patients with depression, and to explore the variables related to QOL changes. Methods Ninety-five inpatients with depression receiving at least 6 ECT sessions and completed all measures were included. Quality of life, symptom severity, and functioning were assessed using Short Form 36 (SF-36), the 17-item Hamilton Rating Scale for Depression (HAMD-17), and the Modified Work and Social Adjustment Scale (MWSAS), before and after ECT. The SF-36 includes 8 subscales, physical component summary (PCS), and mental component summary (MCS). Adverse effects after ECT, including headache, muscle pain, and nausea/vomiting, were also recorded. Results All 8 SF-36 subscales, PCS, MCS, HAMD-17, and MWSAS improved significantly after treatment. Using multiple linear regression analysis, MWSAS changes predicted PCS changes significantly after adjusting for baseline PCS. Similarly, using multiple linear regression analysis, MWSAS changes were significant variables associated with MCS changes after adjusting for ECT frequency, HAMD-17 changes, and baseline MCS. The ECT improved QOL, depressive symptoms, and functioning. Conclusions Whether strategies to enhance functioning during an acute course of ECT could improve QOL is needed to be examined in a further study.","PeriodicalId":287576,"journal":{"name":"The Journal of ECT","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127689346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The Journal of ECTPub Date : 2017-06-01DOI: 10.1097/YCT.0000000000000364
M. Fisher, J. Morrison, P. Jones
{"title":"Electroconvulsive Therapy Practice in New Zealand","authors":"M. Fisher, J. Morrison, P. Jones","doi":"10.1097/YCT.0000000000000364","DOIUrl":"https://doi.org/10.1097/YCT.0000000000000364","url":null,"abstract":"Objectives The aim of this study was to describe the contemporary practice of electroconvulsive therapy (ECT) in New Zealand. Methods A 53-item questionnaire was sent to all services providing ECT as of December 2015. Results Electroconvulsive therapy was provided by 16 services covering 15 district health boards funded by the New Zealand government. No private facilities provided ECT. All services providing ECT responded to an online survey questionnaire. Rates of ECT utilization were low relative to similar countries. Survey results indicated ECT was practiced to an overall good standard. Several resource and logistical issues potentially contributing to low ECT utilization were identified. Conclusions Electroconvulsive therapy in New Zealand is provided using modern equipment and practices. However, overall rates of utilization remain low, perhaps as a result of controversy surrounding ECT and some resourcing issues.","PeriodicalId":287576,"journal":{"name":"The Journal of ECT","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131930947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The Journal of ECTPub Date : 2017-06-01DOI: 10.1097/YCT.0000000000000371
Billy Tran, S. E. O'Donnell, Agnes Balla, David Adams, L. Grondin, Mitchell H. Tsai
{"title":"Electroconvulsive Therapy Considerations for Transgendered Patients.","authors":"Billy Tran, S. E. O'Donnell, Agnes Balla, David Adams, L. Grondin, Mitchell H. Tsai","doi":"10.1097/YCT.0000000000000371","DOIUrl":"https://doi.org/10.1097/YCT.0000000000000371","url":null,"abstract":"As the transgender patient population continues to grow, health care providers will need to become aware of elements unique to the transgender community in order to provide the highest quality of care. Neuromuscular blockade with succinylcholine is routinely administered to patients undergoing electroconvulsive therapy (ECT). Decreased amounts or activity of pseudocholinesterase in serum can lead to prolonged duration of muscle paralysis. Causes of reduced action by pseudocholinesterase include genetically abnormal enzymes, reduced hepatic production, pregnancy, and various drug interactions. Estrogen supplementation taken by transitioning patients may affect the duration of neuromuscular blockade.This is a case of a 32-year-old male-to-female transgender patient with prolonged apnea following ECT treatment for severe, refractory depression. Further investigation revealed the patient was on estrogen therapy as a part of her transition and laboratory testing demonstrated reduced serum pseudocholinesterase activity. Further laboratory testing demonstrated reduced serum pseudocholinesterase activity. Succinylcholine dosing was titrated to an appropriate level to avoid prolonged apnea in subsequent ECT treatments. Physicians and other health care providers are faced with a unique population in the transgender community and must be aware of distinctive circumstances when providing care to this group. Of specific interest, many transitioning and transitioned patients can be on chronic estrogen supplementation. Neuromuscular blockade in those patients require attention from the anesthesiology care team as estrogen compounds may decrease pseudocholinesterase levels and lead to prolonged muscle paralysis from succinylcholine.","PeriodicalId":287576,"journal":{"name":"The Journal of ECT","volume":"89 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114293185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The Journal of ECTPub Date : 2017-06-01DOI: 10.1097/YCT.0000000000000382
R. Katz, Mesut Toprak, R. Ostroff
{"title":"A Successful Course of Electroconvulsive Therapy in a Patient With Epilepsy and a Posterior Fossa Titanium Plate.","authors":"R. Katz, Mesut Toprak, R. Ostroff","doi":"10.1097/YCT.0000000000000382","DOIUrl":"https://doi.org/10.1097/YCT.0000000000000382","url":null,"abstract":"","PeriodicalId":287576,"journal":{"name":"The Journal of ECT","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134327946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}