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Convulsión febril 热性惊厥
Revista Hospital Clínico Universidad de Chile Pub Date : 2023-11-22 DOI: 10.5354/2735-7996.2014.72806
Mario Matamala C., Miguel Guzmán N., Javiera Aguirre E.
{"title":"Convulsión febril","authors":"Mario Matamala C., Miguel Guzmán N., Javiera Aguirre E.","doi":"10.5354/2735-7996.2014.72806","DOIUrl":"https://doi.org/10.5354/2735-7996.2014.72806","url":null,"abstract":"Febrile seizures are the most common seizure disorder in the pediatric population and represent a frequent cause of consultation in emergency departments, confirming its importance. We present an updated and practical review regarding this pathology, along with an operative definition that supports the application of a flowchart that integrates concepts and procedures that can be easily applied at any location nationwide. This review is designed to provide an analytic framework regarding pediatric febrile seizures, as well as present a guideline based on our experience in the emergency department by summarizing the main benzodiazepines in actual use that have been proved to be both safe and effective in treating this disorder, such as lorazepam and midazolam","PeriodicalId":287456,"journal":{"name":"Revista Hospital Clínico Universidad de Chile","volume":"66 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139248361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nuevas estrategias farmacológicas en la enfermedad de Alzheimer: la hiperactividad y la neuroinflamación como nuevos blancos potenciales 阿尔茨海默病的新药理学策略:多动症和神经炎症作为潜在的新靶点
Revista Hospital Clínico Universidad de Chile Pub Date : 2023-08-03 DOI: 10.5354/2735-7996.2023.71414
Pedro Lobos Z., Jamileth More C., Bárbara Bruna J., Antonello Penna S.
{"title":"Nuevas estrategias farmacológicas en la enfermedad de Alzheimer: la hiperactividad y la neuroinflamación como nuevos blancos potenciales","authors":"Pedro Lobos Z., Jamileth More C., Bárbara Bruna J., Antonello Penna S.","doi":"10.5354/2735-7996.2023.71414","DOIUrl":"https://doi.org/10.5354/2735-7996.2023.71414","url":null,"abstract":"Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by the progressive deterioration of cognitive functions such as memory, language, executive function, and visuospatial function, starting from the late ages of life (> 65 years). The etiology of AD is multifactorial involving the interaction of genetic, environmental, and systemic factors. Histopathologically characterized by the progressive accumulation of peptide Aβ and TAU protein. Markers of damage that begin to accumulate decades before symptoms can be detected. However, during the early stages of the disease, systemic inflammation and cortical/hippocampal hyperactivity have been revealed present in patients. In the following review, we present a perspective on how neuroinflammatory processes and pathological cortical hyperexcitability contribute to the onset and development of the early stages of AD. We present a current summary of the basic and clinical evidence that allows us to understand the complexity and heterogeneity of this pathology. Finally, we briefly collect and analyze the main therapeutic strategies that have been studied to reduce the phenotype of neuronal hyperactivity directly or indirectly.","PeriodicalId":287456,"journal":{"name":"Revista Hospital Clínico Universidad de Chile","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134478947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Un extraño caso de trombosis venosa 静脉血栓形成的罕见病例
Revista Hospital Clínico Universidad de Chile Pub Date : 2023-08-03 DOI: 10.5354/2735-7996.2023.71406
María Gabriela Caballero Q., Guillermo Conte L.
{"title":"Un extraño caso de trombosis venosa","authors":"María Gabriela Caballero Q., Guillermo Conte L.","doi":"10.5354/2735-7996.2023.71406","DOIUrl":"https://doi.org/10.5354/2735-7996.2023.71406","url":null,"abstract":"Ovarian vein thrombosis is a rare condition that is usually due to prothrombotic states. The clinical presentation is nonspecific, commonly with abdominal pain. Anticoagulation is fundamental to prevent complications and reduce morbidity and mortality. Enoxaparin and warfarin have traditionally been the anticoagulants of choice. Direct-acting anticoagulants are an alternative under study. This publication presents a case of a 60-year-old patient without predisposing factors for ovarian thrombosis, with low back pain, where the diagnosis was only achieved with Computed Tomography. Anticoagulation with rivaroxaban was started for a period of 3 months, obtaining resolution of symptoms and thrombosis.","PeriodicalId":287456,"journal":{"name":"Revista Hospital Clínico Universidad de Chile","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133624800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reconstrucción nasal secundaria con injerto costal: caso clínico y revisión de la literatura 肋移植继发性鼻重建:临床病例及文献综述
Revista Hospital Clínico Universidad de Chile Pub Date : 2023-08-03 DOI: 10.5354/2735-7996.2023.71407
T. González A., Sally Costa C., Nicolás Espinoza C., C. Erazo C.
{"title":"Reconstrucción nasal secundaria con injerto costal: caso clínico y revisión de la literatura","authors":"T. González A., Sally Costa C., Nicolás Espinoza C., C. Erazo C.","doi":"10.5354/2735-7996.2023.71407","DOIUrl":"https://doi.org/10.5354/2735-7996.2023.71407","url":null,"abstract":"Introduction: Secondary rhinoplasty, or reintervention, is a surgery on a previously operated nose, which represents a greater surgical challenge compared to primary rhinoplasty. The ideal is the use of autologous cartilage graft since it meets biocompatibility characteristics and resembles an ideal graft. The costal cartilage is a good alternative since it has characteristics similar to septal cartilage, with the advantage of offering a larger amount of material to work with and it does not deform over time. Clinical case: male, 31 years old, admitted due to a hit to the face with a blunt object. It evidenced complex facial fracture, with Le Fort I components on the right and Le Fort III components on the left, as well as a left naso-orbital-ethmoid fracture. It performs reduction and intermaxillary fixation. It performs nasal reconstruction with a double nasal cartilage graft and bone graft for the back, and septal cartilage graft to construct the columella stem. It plans secondary rhinoplasty with a seventh rib graft correct the saddle nose defect. Outpatient follow-up at 14 and 30 days with favorable cosmetic results. Discussion: This procedure generally gives good results with a low complication rate. In the latest systematic reviews with an average follow-up of 14.4 months (6-96 months) they concluded that in the donor area the most frequent complication was the development of scars in the surgical site with 2.08% (0. 31-4.83%) and pneumothorax was close to 0% (0-0.46%). In the recipient area, the most frequent were graft retraction with 3.05% (1.35-5.19%) and 1.45% (0.34-3.06%) of infection of the recipient area. Conclusion: With the presentation of this clinical case, you can observed that the use of costal cartilage in secondary rhinoplasty is an achievable option, with good results in the short and medium term, in addition to having a low rate of complications, but a team of experienced plastic surgery must perform it. \u0000Fecha recepción: noviembre 2022 | Fecha aceptación: febrero","PeriodicalId":287456,"journal":{"name":"Revista Hospital Clínico Universidad de Chile","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132016533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigación, innovación y desarrollo tecnológico en el Hospital Clínico Universidad de Chile 智利大学临床医院的研究、创新和技术发展
Revista Hospital Clínico Universidad de Chile Pub Date : 2023-08-03 DOI: 10.5354/2735-7996.2023.71243
P. Délano R.
{"title":"Investigación, innovación y desarrollo tecnológico en el Hospital Clínico Universidad de Chile","authors":"P. Délano R.","doi":"10.5354/2735-7996.2023.71243","DOIUrl":"https://doi.org/10.5354/2735-7996.2023.71243","url":null,"abstract":"No abstract available","PeriodicalId":287456,"journal":{"name":"Revista Hospital Clínico Universidad de Chile","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134448200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstracts Jornadas de Calidad 2017 2017年质量会议摘要
Revista Hospital Clínico Universidad de Chile Pub Date : 2023-05-12 DOI: 10.5354/2735-7996.2017.70647
Revista Hospital Clínico Universidad de Chile
{"title":"Abstracts Jornadas de Calidad 2017","authors":"Revista Hospital Clínico Universidad de Chile","doi":"10.5354/2735-7996.2017.70647","DOIUrl":"https://doi.org/10.5354/2735-7996.2017.70647","url":null,"abstract":"Desde hace unos años, el Hospital Clínico Universidad de Chile a través de su Dirección de Calidad ha esta- \u0000blecido un espacio de desarrollo y enriquecimiento institucional de sus prácticas y está enfocado en contribuir \u0000a la formación de una cultura de calidad y seguridad de los pacientes que permita posicionar y alinear la \u0000calidad en todos los niveles del quehacer de su Institución. Es por esto que desde hace unos años organiza las \u0000Jornadas de Calidad HCUCH en las cuales se presentan trabajos realizados localmente que tuvieron como \u0000objetivo la obtención de mejores resultados en la atención de los pacientes. A continuación compartimos los \u0000trabajos presentados en su versión 2017.","PeriodicalId":287456,"journal":{"name":"Revista Hospital Clínico Universidad de Chile","volume":"59 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128189708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Serie guías clínicas: manejo de la hipertensión crónica en el embarazo 临床指南系列:妊娠期慢性高血压的管理
Revista Hospital Clínico Universidad de Chile Pub Date : 2023-05-09 DOI: 10.5354/2735-7996.2017.70606
Álvaro Sepúlveda-Martínez, E. Segovia R, Mauro Parra-Cordero
{"title":"Serie guías clínicas: manejo de la hipertensión crónica en el embarazo","authors":"Álvaro Sepúlveda-Martínez, E. Segovia R, Mauro Parra-Cordero","doi":"10.5354/2735-7996.2017.70606","DOIUrl":"https://doi.org/10.5354/2735-7996.2017.70606","url":null,"abstract":"1. Conocer la morbilidad materna asociada a la hipertensión durante el embarazo. \u00002. Conocer la morbilidad fetal y perinatal asociada a la hipertensión durante el embarazo. \u00003. Aplicar las estrategias de prevención de preeclampsia en pacientes hipertensas. \u00004. Conocer la terapia farmacológica validada para el manejo de la hipertensión durante el \u0000embarazo. \u00005. Determinar cifras tensionales para inicio de terapia farmacológica antihipertensiva oral. \u00006. Determinar cifras tensionales para inicio de terapia antihipertensiva endovenosa. \u00007. Aplicar metas tensionales para el manejo farmacológico antihipertensivo. \u00008. Establecer la edad gestacional de interrupción de pacientes portadoras de hipertensión \u0000arterial crónica. \u00009. Aplicar terapias antihipertensivas recomendadas durante la lactancia.","PeriodicalId":287456,"journal":{"name":"Revista Hospital Clínico Universidad de Chile","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114077235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Calprotectina fecal: utilidad en el diagnóstico diferencial de enfermedad inflamatoria intestinal y síndrome intestino irritable en adultos 粪便钙保护素:用于鉴别诊断成人炎症性肠病和肠易激综合征
Revista Hospital Clínico Universidad de Chile Pub Date : 2023-04-18 DOI: 10.5354/2735-7996.2018.70354
Natalia Covarrubias R., A. Madrid S., René Rojas B., M. Gompertz G.
{"title":"Calprotectina fecal: utilidad en el diagnóstico diferencial de enfermedad inflamatoria intestinal y síndrome intestino irritable en adultos","authors":"Natalia Covarrubias R., A. Madrid S., René Rojas B., M. Gompertz G.","doi":"10.5354/2735-7996.2018.70354","DOIUrl":"https://doi.org/10.5354/2735-7996.2018.70354","url":null,"abstract":"Differentiation between inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS) can be complex as their symptoms are often similar and unspecific. Fecal biomarkers could be useful to select patients with suspected organic diseases for colonoscopy, with the aim to improve early diagnosis and to avoid unnecessary invasive studies. Fecal calprotectin (FC) is a protein found mainly in neutrophils that is released into the feces as a result of cell disruption and apoptosis. Currently, FC is a simple and non-invasive biomarker of intestinal inflammation. Inflammatory gastrointestinal disorders are associated with high levels of FC, as occurs in IBD. This review focuses on FC as a useful tool for differential diagnosis between IBS and IBD in adults.","PeriodicalId":287456,"journal":{"name":"Revista Hospital Clínico Universidad de Chile","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117238586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstracts Jornadas Calidad 2018 2018年质量会议摘要
Revista Hospital Clínico Universidad de Chile Pub Date : 2023-04-18 DOI: 10.5354/2735-7996.2018.70356
Revista Hospital Clínico Universidad de Chile
{"title":"Abstracts Jornadas Calidad 2018","authors":"Revista Hospital Clínico Universidad de Chile","doi":"10.5354/2735-7996.2018.70356","DOIUrl":"https://doi.org/10.5354/2735-7996.2018.70356","url":null,"abstract":"Desde hace unos añ os, el Hospital Clínico Universidad de Chile a través de su Dirección de Calidad ha esta- \u0000blecido un espacio de desarrollo y enriquecimiento institucional de sus prácticas, enfocado en contribuir a la \u0000formación de una cultura de calidad y seguridad de los pacientes que permita alinear éstas en todos los niveles \u0000del quehacer de su Institución. \u0000Es por esto que se ha establecido como una de las estrategias de difusión, ampliación y profundización de los \u0000temas de seguridad y calidad institucional, la realización de las Jornadas de Calidad HCUCH. En ellas se \u0000presentan trabajos que corresponden a iniciativas locales que tuvieron como objetivo la obtención de mejores \u0000resultados en la atención de los pacientes. A continuación compartimos una selección de los trabajos presenta- \u0000dos en su versión 2018.","PeriodicalId":287456,"journal":{"name":"Revista Hospital Clínico Universidad de Chile","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129480467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Resúmenes IV Jornadas de Investigación 2022: "Salud e ingeniería: soluciones innovadoras en HCUCH" 四、2022年研究会议摘要:“健康与工程:HCUCH的创新解决方案”
Revista Hospital Clínico Universidad de Chile Pub Date : 2023-04-18 DOI: 10.5354/2735-7996.2023.70355
Revista Hospital Clínico Universidad de Chile
{"title":"Resúmenes IV Jornadas de Investigación 2022: \"Salud e ingeniería: soluciones innovadoras en HCUCH\"","authors":"Revista Hospital Clínico Universidad de Chile","doi":"10.5354/2735-7996.2023.70355","DOIUrl":"https://doi.org/10.5354/2735-7996.2023.70355","url":null,"abstract":"No abstract available","PeriodicalId":287456,"journal":{"name":"Revista Hospital Clínico Universidad de Chile","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122189981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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