EMJ Cardiology最新文献

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Profiling the Discordant Visceral Adipose Tissue–Ectopic Liver Fat Phenotype: Results from the Dallas Heart Study 剖析不一致内脏脂肪组织-异位肝脏脂肪表型:来自达拉斯心脏研究的结果
EMJ Cardiology Pub Date : 2020-08-31 DOI: 10.33590/emjcardiol/2008313
{"title":"Profiling the Discordant Visceral Adipose Tissue–Ectopic Liver Fat Phenotype: Results from the Dallas Heart Study","authors":"","doi":"10.33590/emjcardiol/2008313","DOIUrl":"https://doi.org/10.33590/emjcardiol/2008313","url":null,"abstract":"The accumulation of visceral adipose tissue (VAT) and ectopic liver fat (ELF) generally parallel each other, but a proportion of individuals have discordant fat deposition. The cardiometabolic profile of individuals with a discordant phenotype is unknown.","PeriodicalId":284912,"journal":{"name":"EMJ Cardiology","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125090883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
High Prevalence of Metabolic Factors in Both Young and Old Patients with Acute Coronary Syndrome - Interim Results of Metabolic Risk Factors in First ACS Study (Merifacs) 代谢因素在青年和老年急性冠脉综合征患者中的高发——ACS首次研究中代谢危险因素的中期结果
EMJ Cardiology Pub Date : 2020-08-31 DOI: 10.33590/emjcardiol/2008311
H. Rao, S. Ramaraju, Namagiri, Srinivas R. Chejarla
{"title":"High Prevalence of Metabolic Factors in Both Young and Old Patients with Acute Coronary Syndrome - Interim Results of Metabolic Risk Factors in First ACS Study (Merifacs)","authors":"H. Rao, S. Ramaraju, Namagiri, Srinivas R. Chejarla","doi":"10.33590/emjcardiol/2008311","DOIUrl":"https://doi.org/10.33590/emjcardiol/2008311","url":null,"abstract":"The study recruited consecutive consenting patients >18 years with the diagnosis of first ACS. Patients were treated as per standard of care. Data on demographic profile, socioeconomic status, risk factors, and in-hospital treatment were captured. CRF were active smoking, hypertension, diabetes, and high low-density lipoprotein levels. MRF were above normal values of BMI, waist–hip ratio, HbA1c, S-triglycerides, and low high-density lipoprotein levels. Statistical analysis was performed using SPSS software.","PeriodicalId":284912,"journal":{"name":"EMJ Cardiology","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127869808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Progression of Valvular Calcification is Associated with 10-Year Change in Left Ventricular Structure and Incident Heart Failure: MESA 瓣膜钙化进展与10年左心室结构变化和心力衰竭事件有关
EMJ Cardiology Pub Date : 2020-08-31 DOI: 10.33590/emjcardiol/2008312
{"title":"Progression of Valvular Calcification is Associated with 10-Year Change in Left Ventricular Structure and Incident Heart Failure: MESA","authors":"","doi":"10.33590/emjcardiol/2008312","DOIUrl":"https://doi.org/10.33590/emjcardiol/2008312","url":null,"abstract":"Heart failure (HF) is a leading cause of morbidity.1 It results from impairment in ventricular filling or relaxation and can be broadly classified as heart failure with preserved ejection fraction (HFpEF) or with reduced ejection fraction (HFrEF).2 Strategies for preventing HF are paramount. Prevalent coronary artery calcium and extracoronary calcification are associated with future coronary heart disease3-7 and HF8 events. Less is known about the impact of progression of valvular calcification (VC) (mitral annular [MAC] and aortic valve calcification [AVC]) on HF risk.","PeriodicalId":284912,"journal":{"name":"EMJ Cardiology","volume":"75 1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123216338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Case Report: Inhaled Nitroglycerine as an Alternative to Inhaled Nitric Oxide in the Acute Treatment of Pulmonary Hypertension and Impending Acute Right Ventricular Failure in the Intensive Care Unit 病例报告:吸入硝酸甘油替代吸入一氧化氮治疗重症监护室肺动脉高压和危重急性右心衰
EMJ Cardiology Pub Date : 2020-06-01 DOI: 10.33590/emj/19-00194
K. Sorour, Christopher Lawson, Omar Sorour, Garrison Davis
{"title":"Case Report: Inhaled Nitroglycerine as an Alternative to Inhaled Nitric Oxide in the Acute Treatment of Pulmonary Hypertension and Impending Acute Right Ventricular Failure in the Intensive Care Unit","authors":"K. Sorour, Christopher Lawson, Omar Sorour, Garrison Davis","doi":"10.33590/emj/19-00194","DOIUrl":"https://doi.org/10.33590/emj/19-00194","url":null,"abstract":"In this review, two cases of severe pulmonary hypertension of different classes that have been successfully treated using inhaled nitroglycerine are presented. In a community hospital setting and in cases of life-threatening right heart failure and shock not responding to simple traditional treatments, thought should be given to the use of inhaled nitroglycerine. Inhaled nitroglycerine is practical, cheap, and readily available in any hospital without reconstitution. This approach may allow for the treatment, or at least temporary stabilisation, of these patients until transferred to a tertiary care facility.","PeriodicalId":284912,"journal":{"name":"EMJ Cardiology","volume":"131 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127372504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Impact of Routine Cardiology Consultation on Critically Ill Patients with Elevated Troponin Levels 心内科常规会诊对肌钙蛋白水平升高危重患者的影响
EMJ Cardiology Pub Date : 2020-03-01 DOI: 10.1016/s0735-1097(20)30823-8
O. Kousa, A. Essa, M. Ahsan, Venkata S. Pajjuru, Abedelrahman Anani, Mohammed Saleh, Aiza Ahmad, Janani Baskaran, Yaman Alali, R. Walters, T. Haddad, A. Smer
{"title":"The Impact of Routine Cardiology Consultation on Critically Ill Patients with Elevated Troponin Levels","authors":"O. Kousa, A. Essa, M. Ahsan, Venkata S. Pajjuru, Abedelrahman Anani, Mohammed Saleh, Aiza Ahmad, Janani Baskaran, Yaman Alali, R. Walters, T. Haddad, A. Smer","doi":"10.1016/s0735-1097(20)30823-8","DOIUrl":"https://doi.org/10.1016/s0735-1097(20)30823-8","url":null,"abstract":"","PeriodicalId":284912,"journal":{"name":"EMJ Cardiology","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125942190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Edge-to-Edge Repair After Prior Left-Sided Pneumonectomy 先前左侧全肺切除术后的边缘到边缘修复
EMJ Cardiology Pub Date : 2019-11-22 DOI: 10.33590/emjcardiol/19-00068
Mohammed Nasser Abdel-Hadi, P. Staszewicz, M. Bayer, M. Moscoso-Ludueña, B. Abt, D. Fischer, H. Nef, A. Rastan
{"title":"Edge-to-Edge Repair After Prior Left-Sided Pneumonectomy","authors":"Mohammed Nasser Abdel-Hadi, P. Staszewicz, M. Bayer, M. Moscoso-Ludueña, B. Abt, D. Fischer, H. Nef, A. Rastan","doi":"10.33590/emjcardiol/19-00068","DOIUrl":"https://doi.org/10.33590/emjcardiol/19-00068","url":null,"abstract":"Cardiac surgery procedures for patients following previous pneumonectomy are challenging because of anaesthetic and cardio-surgical technical difficulties. Here, the case of a patient who had received a left-sided pneumectomy 13 years prior as a result of nonsmall cell lung cancer is presented. A mitral edge-to-edge clipping was applied with excellent success in treating severe mitral regurgitation attributable to flail of the posterior mitral valve leaflet (fibroelastic deficiency). Because the heart was severely left-displaced, the use of transoesophageal echo during the preinterventional screening was challenging but feasible, and imaging quality was good. The absence of left pulmonary veins demanded a guide catheter and clip delivery system to be introduced during the procedure through the use of a spiral, preshaped, stiff guidewire. The procedure was performed under general anaesthesia with the patient extubated on a table. No complications arose during the periprocedural period and hospital stay, and after 3 months’ follow-up the patient showed significant functional improvement.","PeriodicalId":284912,"journal":{"name":"EMJ Cardiology","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124689125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Raiders of the Lost Wire 《夺宝奇兵
EMJ Cardiology Pub Date : 2019-11-15 DOI: 10.33590/emjcardiol/18-00120
C. Salazar, G. Tirado, Angela Mclnerney, L. Nombela‐Franco, I. Núñez-Gil
{"title":"Raiders of the Lost Wire","authors":"C. Salazar, G. Tirado, Angela Mclnerney, L. Nombela‐Franco, I. Núñez-Gil","doi":"10.33590/emjcardiol/18-00120","DOIUrl":"https://doi.org/10.33590/emjcardiol/18-00120","url":null,"abstract":"Introduction: An angiographic guidewire is a basic, yet essential piece of equipment in the interventional cardiologist’s armamentarium. Complications associated with angiographic guidewires can be catastrophic to the safe completion of a coronary procedure. In this article, the authors report a case of angiography guidewire fracture and explore the options for management of this rare but serious complication.\u0000\u0000Case presentation: A 77-year-old man with multiple cardiovascular risk factors was admitted with an anterior ST segment elevation myocardial infarction. Diagnostic angiography was performed via right radial access and revealed a subocclusive stenosis of the mid and distal left anterior descending artery (LAD) with thrombolysis in myocardial infarction 1 flow and a 70% stenosis of the proximal diagonal branch. Primary percutaneous coronary intervention was attempted and a HI-TORQUE Balance Middle Weight Universal II guidewire (Abbott Vascular Inc., Santa Clara, California, USA) was chosen. Guidewire manipulation was difficult because of significant calcification and tortuosity of the LAD. Consequently, the guidewire fractured and became trapped in the mid-LAD. The complication was ultimately resolved by stenting across the fractured guidewire and the patient was not afflicted by any adverse sequelae.\u0000\u0000Discussion: This case highlights a rare but potentially serious complication of coronary intervention. Proposed management varies from leaving the fractured wire in situ and stenting across it, to varying techniques for removing the fractured wire. However, no consensus exists as to the best strategy. The authors have therefore performed a review of the current literature and propose an algorithm for the management of this rare complication.","PeriodicalId":284912,"journal":{"name":"EMJ Cardiology","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123590884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Lipoprotein(a) and Calcific Aortic Valve Stenosis 脂蛋白(a)与钙化性主动脉瓣狭窄
EMJ Cardiology Pub Date : 2019-10-17 DOI: 10.33590/emjcardiol/10310024
C. E. Kosmas, D. Silverio, A. Sourlas, F. Campos, Peter D. Montan, Eliscer Guzman
{"title":"Lipoprotein(a) and Calcific Aortic Valve Stenosis","authors":"C. E. Kosmas, D. Silverio, A. Sourlas, F. Campos, Peter D. Montan, Eliscer Guzman","doi":"10.33590/emjcardiol/10310024","DOIUrl":"https://doi.org/10.33590/emjcardiol/10310024","url":null,"abstract":"Calcific aortic valve stenosis is the most common valve disease in the elderly population and is associated with significant morbidity and mortality. This condition is characterised by gradual fibrosis, thickening, and calcification of the affected leaflets, leading to decreased leaflet mobility and increased obstruction of the blood flow from the left ventricle. Lipoprotein(a) [Lp(a)] is a complex polymorphic lipoprotein with proatherogenic, proinflammatory, and prothrombotic properties. Several epidemiologic and clinical studies have described elevated Lp(a) levels as an independent causative risk factor for cardiovascular disease, including coronary artery disease, stroke, peripheral artery disease, heart failure, and venous thromboembolism. On the other hand, several studies have also described Lp(a) as a strong genetic causative risk factor for aortic valve calcification and aortic valve stenosis. In this review, the authors present and discuss the scientific and clinical evidence pertaining to the role of Lp(a) in calcific aortic valve stenosis.\u0000\u0000INTRODUCTIO","PeriodicalId":284912,"journal":{"name":"EMJ Cardiology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129682286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
European Society of Cardiology Chronic Coronary Syndromes Guidelines Review 欧洲心脏病学会慢性冠状动脉综合征指南综述
EMJ Cardiology Pub Date : 2019-10-17 DOI: 10.33590/emjcardiol/10313179
Samantha Stanbury
{"title":"European Society of Cardiology Chronic Coronary Syndromes Guidelines Review","authors":"Samantha Stanbury","doi":"10.33590/emjcardiol/10313179","DOIUrl":"https://doi.org/10.33590/emjcardiol/10313179","url":null,"abstract":"New guidelines for the diagnosis and management of chronic coronary syndromes (CCS)1were released during the 2019 European Society of Cardiology (ESC) Congress. The new guidelines were discussed in multiple sessions with different formats across the congress; this review summarises some of the discussion among experts at the congress around what the new guidelines mean for the way they manage their patients with respect to antithrombotic treatment.\u0000\u0000A significant change in the new guidelines versus previous guidelines published in 20132is an update in nomenclature from ‘stable’ coronary artery disease (CAD) to chronic coronary syndromes, to reflect the fact that patients with CCS are at continuous risk of heart attacks, strokes, and death. This highlights the need for effective preventive therapy to protect against these thrombotic events and maintain a state of relative stability in patients with CCS. To this end, a new recommendation in the 2019 guidelines is to consider intensification of antithrombotic therapy, using aspirin plus another antithrombotic agent, to provide enhanced long-term protection for patients with CCS at high risk of ischaemic events. This review places the new guideline recommendations in clinical perspective, including thorough presentations of case studies to illustrate how patients at greatest risk of ischaemic events can be identified, and treatment stratified accordingly. These case studies highlight the role of dual pathway inhibition (DPI) in managing CCS patients with the greatest need for cardiovascular protection, who are likely to derive the greatest benefit from this treatment strategy.","PeriodicalId":284912,"journal":{"name":"EMJ Cardiology","volume":"75 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130210325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Why the Diagnosis of ATTR-Cardiomyopathy May Be a Challenge for Physicians 为什么atr -心肌病的诊断对医生来说可能是一个挑战
EMJ Cardiology Pub Date : 2019-10-17 DOI: 10.33590/emjcardiol/10310030
Nick Lamb
{"title":"Why the Diagnosis of ATTR-Cardiomyopathy May Be a Challenge for Physicians","authors":"Nick Lamb","doi":"10.33590/emjcardiol/10310030","DOIUrl":"https://doi.org/10.33590/emjcardiol/10310030","url":null,"abstract":"Cardiac amyloidosis is a rare but life-threatening group of disorders caused by the extracellular deposition of misfolded amyloid fibrils in cardiac tissue. Amyloid accumulation leads to cardiomyocyte toxicity, extracellular volume expansion, and ventricular pseudohypertrophy. Two types of amyloid protein are thought to be responsible for most disorders: immunoglobulin light chain, which causes light chain amyloidosis (AL); and transthyretin (TTR), which causes transthyretin amyloidosis (ATTR), of which there are two types: hereditary (hATTR) or wild-type (ATTRwt). Despite increasing clinical recognition of the disease, cardiac amyloidosis remains underdiagnosed. This article explores the epidemiology of AL and ATTR and the noninvasive techniques that help to improve diagnosis of the disorder. Cardiac amyloidosis is associated with mixed phenotype symptoms of polyneuropathy and cardiomyopathy which can lead to multiple misdiagnoses. As a result, patients can wait between 2 and 4 years for a correct diagnosis. Early diagnosis may be aided by recognising red flag symptom clusters. These include family history; neuropathy and sensory involvement; bilateral carpal tunnel syndrome; early autonomic dysfunction and gastrointestinal complaints; heart failure (HF) with preserved ejection fraction (HFpEF; without hypertension); cardiac hypertrophy, arrhythmias, ventricular blocks, right-sided or biventricular HF, or cardiomyopathy; renal abnormalities; and vitreous opacities. Noninvasive imaging techniques have increasingly been used as an alternative to biopsy to diagnose cardiac amyloidosis with the hope of allowing physicians to provide targeted therapy for these patients. Techniques include speckle tracking echocardiography, cardiac MRI, and nuclear scintigraphy, together with biomarkers such as N-terminal pro-brain natriuretic peptide and hepatocyte growth factor (HGF). It is hoped that greater understanding of patients with ATTR may lead to increased awareness of the disorder and improve patient outcomes.","PeriodicalId":284912,"journal":{"name":"EMJ Cardiology","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133406232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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