Przemysław Zygmunciak, Justyna Iskrzak, Joanna Góra-Tybor, Ewa Lech-Marańda, B. Puła
{"title":"Ruxolitinib as a primary treatment for multiple myeloma in a patient with primary myelofibrosis? A case report and the review of the literature","authors":"Przemysław Zygmunciak, Justyna Iskrzak, Joanna Góra-Tybor, Ewa Lech-Marańda, B. Puła","doi":"10.5603/hicp.95649","DOIUrl":"https://doi.org/10.5603/hicp.95649","url":null,"abstract":"An 80-year-old female with a history of primary myelofibrosis was admitted to the hospital due to worsening symptoms of the primary disease. A secondary tumor — multiple myeloma (MM) — was revealed during the diagnostic process. Monotherapy with a JAK inhibitor (ruxolitinib) was administered, and the severity of both malignancies was alleviated. This article includes a short review of secondary malignancies correlated with PMF and the state of knowledge on using JAK inhibitors, mainly ruxol-itinib, in treating MM","PeriodicalId":284891,"journal":{"name":"Hematology in Clinical Practice","volume":"115 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139341161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marika Kasahara, Kajetan Karaszewski, Maria Król, M. Ziarkiewicz, W. W. Jędrzejczak
{"title":"Incidence of lymphoid malignancies in patients with lymphocytosis identified by general practitioners","authors":"Marika Kasahara, Kajetan Karaszewski, Maria Król, M. Ziarkiewicz, W. W. Jędrzejczak","doi":"10.5603/hicp.91605","DOIUrl":"https://doi.org/10.5603/hicp.91605","url":null,"abstract":"","PeriodicalId":284891,"journal":{"name":"Hematology in Clinical Practice","volume":"98 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139341185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Samet Yaman, Yağmur Kınacı Gümüşçubuk, Oğuzcan Gümüşçubuk, Berkan Karabuğa, S. Akıncı, I. Dilek
{"title":"Oral iron absorption test: myth or reality?","authors":"Samet Yaman, Yağmur Kınacı Gümüşçubuk, Oğuzcan Gümüşçubuk, Berkan Karabuğa, S. Akıncı, I. Dilek","doi":"10.5603/hicp.93373","DOIUrl":"https://doi.org/10.5603/hicp.93373","url":null,"abstract":"common etiology is iron deficiency anemia (IDA). The oral iron absorption test (OIAT) is a method that has been used for a long time to demonstrate the level of iron absorption in patients, but it has not reached widespread use in clinical practice. The study aims to analyze predictive factors of iron absorption in patients with IDA. Material and methods: A total of 108 patients between the ages of 18–65 who were diagnosed with IDA were included and patients with concomitant inflammatory bowel disease, celiac disease, history of gastrointestinal surgery, malignancy, using iron therapy, and patients with unavailable data were excluded from the study. OIAT applied to 108 patients. Results: Female patients form the majority of the cohort (n = 100, 92.6%). OIAT was administered to 54 patients in tablet form and 54 patients in capsule form. The following study compared 88 patients with adequate oral iron absorption and 20 patients with insufficient oral iron absorption. Less iron absorption was found in male patients (p = 0.04) with increasing age, and it was statistically significant (p = 0.02). Conclusion: The result of the current study demonstrated that male gender and older age have a significant impact on iron absorption. OIAT is recommended at the time of diagnosis in elderly patients and male patients so that the underlying cause can be identified without delay in the insufficient iron absorption group. Additionally, patients with oral iron absorption disorders can be diagnosed at an early stage by applying the OIAT.","PeriodicalId":284891,"journal":{"name":"Hematology in Clinical Practice","volume":"124 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139341087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sara Maria Soto, Carlos Andres Portilla, H. García-Perdomo
{"title":"Clinical and demographic characteristics of sickle cell disease in colombian children","authors":"Sara Maria Soto, Carlos Andres Portilla, H. García-Perdomo","doi":"10.5603/hicp.92422","DOIUrl":"https://doi.org/10.5603/hicp.92422","url":null,"abstract":"","PeriodicalId":284891,"journal":{"name":"Hematology in Clinical Practice","volume":"65 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139341106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Magdalena Ostojska, Katarzyna Karska, Monika Lejman, Joanna Zawitkowska
{"title":"Effective treatment of severe forms of RSV and Pneumocystis jirovecii infections in a child with Down syndrome and acute lymphoblastic leukemia treated with chemotherapy","authors":"Magdalena Ostojska, Katarzyna Karska, Monika Lejman, Joanna Zawitkowska","doi":"10.5603/hcp.2023.0001","DOIUrl":"https://doi.org/10.5603/hcp.2023.0001","url":null,"abstract":"","PeriodicalId":284891,"journal":{"name":"Hematology in Clinical Practice","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126724173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Bobrowicz, Magdalena Góralska, Aleksandra Kusowska, Anna Skowrońska-Szcześniak, T. Bednarczuk
{"title":"Endocrine-related adverse events associated with targeted treatment and immune checkpoint blockage in hematological malignancies","authors":"M. Bobrowicz, Magdalena Góralska, Aleksandra Kusowska, Anna Skowrońska-Szcześniak, T. Bednarczuk","doi":"10.5603/hcp.2023.0003","DOIUrl":"https://doi.org/10.5603/hcp.2023.0003","url":null,"abstract":"","PeriodicalId":284891,"journal":{"name":"Hematology in Clinical Practice","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121408385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Korzeniowska, A. Cieślewicz, Katarzyna Grabańska-Martyńska, Anna Flotyńska, A. Jabłecka
{"title":"Pulmonary embolism after anti-SARS-CoV-2 vaccines in two female patients","authors":"K. Korzeniowska, A. Cieślewicz, Katarzyna Grabańska-Martyńska, Anna Flotyńska, A. Jabłecka","doi":"10.5603/hcp.2023.0004","DOIUrl":"https://doi.org/10.5603/hcp.2023.0004","url":null,"abstract":"","PeriodicalId":284891,"journal":{"name":"Hematology in Clinical Practice","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130907692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Parvaneh Tavakoli Afshar, Zohreh Taherian, N. Nouri, E. Zaker, S. Asadi, Farzaneh Rami, Roya Bakhtiari, M. Hosseinzadeh, Mansoor Salehi
{"title":"Study of type and frequency of Alfa-thalassemia mutations in a cohort of 3,823 patients from Isfahan Province, Iran","authors":"Parvaneh Tavakoli Afshar, Zohreh Taherian, N. Nouri, E. Zaker, S. Asadi, Farzaneh Rami, Roya Bakhtiari, M. Hosseinzadeh, Mansoor Salehi","doi":"10.5603/hcp.2023.0005","DOIUrl":"https://doi.org/10.5603/hcp.2023.0005","url":null,"abstract":"","PeriodicalId":284891,"journal":{"name":"Hematology in Clinical Practice","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132031077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"How do I manage the myelotoxicity of venetoclax and azacitidine in patients with newly diagnosed acute myeloid leukemia?","authors":"Aleksander Salomon-Perzyński, B. Budziszewska","doi":"10.5603/hcp.2023.0002","DOIUrl":"https://doi.org/10.5603/hcp.2023.0002","url":null,"abstract":"","PeriodicalId":284891,"journal":{"name":"Hematology in Clinical Practice","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134104442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Szczepaniak, L. Gil, S. Giebel, G. Helbig, T. Wróbel, J. Zaucha, B. Budziszewska, A. Wierzbowska
{"title":"Practical aspects of the use of ventoclax in combination with azacitidine for the treatment of newly diagnosed acute myeloid leukaemia in patients ineligible for intensive chemotherapy","authors":"A. Szczepaniak, L. Gil, S. Giebel, G. Helbig, T. Wróbel, J. Zaucha, B. Budziszewska, A. Wierzbowska","doi":"10.5603/hcp.a2022.0018","DOIUrl":"https://doi.org/10.5603/hcp.a2022.0018","url":null,"abstract":"","PeriodicalId":284891,"journal":{"name":"Hematology in Clinical Practice","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122721622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}