Prime Archives in Nutrition最新文献

{"title":"The Intake of Extremely Low Minerals and Bacteria Consumable Saccharides Secured Safety and Persistent of 7-14 Days Prolonged Total Dietary Deprivation Regimen","authors":"Xiaoxue Wang, Yancong Zhao, Yaying Yu, Yi Chen, Chenguang Niu, Q. Wei, Hongxia Xu, Xinxin Liu, Chenlu Zhang, Xiaolong Zheng, Cheng-gang Zhang, Garrick D. Lee","doi":"10.37247/PAN.1.2021.13","DOIUrl":"https://doi.org/10.37247/PAN.1.2021.13","url":null,"abstract":"ALT The Intake of Extremely Low Minerals and Bacteria Consumable Saccharides Secured Safety and Persistent of 7-14 Days Prolonged Total Dietary Deprivation Regimen. In: Abstract Objectives: The aim of this study was to evaluate a total fasting regimen assisted by a novel prebiotic, Flexible Abrosia (FA), in more than 7 days of continual dietary deprivation (7D-CDD). Our analysis included basic physical examinations, bioelectrical impedance analysis, and clinical lab and ELISA analysis in normal volunteers. Methods : Eight healthy subjects with normal body weight participated in 7D-CDD with the assistance of a specially designed probiotic. Individuals were assigned to take FA (113.4 KJ/10g/dose) at each mealtime to avoid possible injuries to intestinal flora and smooth the hunger sensation. During 7D-CDD, the subjects were advised to avoid any food intake, especially carbohydrates, except for drinking plentiful amounts of water. The examination samples were collected before CDD as self-control, at 7-d fasting, and after 7~14 d of refeeding. Four subjects were also tested after 6-m refeeding. Results: The FA-CDD regimen significantly decreased suffering from starvation, with tolerable hunger sensations during the treatment. With the addition of daily mineral electrolytes, the subjects not only passed through the entire 7D-CDD regimen but also succeed in up to 14D total fasting in three subjects. There was a significant reduction in blood glucose, insulin, and high-density lipoprotein levels during fasting, and the blood concentrations of uric acid (UA), alanine aminotransferase (ALT), and creatine kinase (CK) were increased. However, after more than 2 months of refeeding, the disease markers ALT, GOT, and CK either remained stable or were slightly downregulated compared to their initial 0 D control level. Conclusion: Our experiment has supplied the first positive evidence that, with the assistance of a daily nutritional supply around 100 kcal total calories to their intestinal flora, human subjects were able to tolerate hunger sensations. We have found that, although 7D-CDD induced increases in UA, CK, and transferases during fasting, refeeding led the markers to become either down-regulated or unchanged compared to their initial levels. This phenomenon was further confirmed in longer-term (6 m) recovery. Our results failed to support the hypothesis that fasting induced liver damage, since ALT, GOT, and CK remained low after longer-term refeeding. Our findings indicate that our 7D-CDD regimen which target of Intestinal flora saturation might be practical and that it might be valuable to design larger clinical fasting trials for improvement of health strategy-targeting in metabolic disorders.","PeriodicalId":284374,"journal":{"name":"Prime Archives in Nutrition","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117183096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Concept, Etiology and Current Diagnostic and Treatment Approaches of Histamine Intolerance: A Review","authors":"Oriol Comas-Basté, Sònia Sánchez-Pérez, M. T. Veciana-Nogués, M. Latorre-Moratalla, María del Carmen Vidal-Carou","doi":"10.37247/PAN.1.2021.10","DOIUrl":"https://doi.org/10.37247/PAN.1.2021.10","url":null,"abstract":"Histamine intolerance, also referred to as enteral histaminosis or sensitivity to dietary histamine, is a disorder associated with an impaired ability to metabolize ingested histamine that was described at the beginning of the 21st century. Although interest in histamine intolerance has considerably grown in recent years, more scientific evidence is still required to help define, diagnose and clinically manage this condition. This book chapter will provide an updated review on histamine intolerance, mainly focusing on its etiology and the existing diagnostic and treatment strategies. In this work, a glance on histamine intoxication will also be provided, as well as the analysis of certain uncertainties historically associated to histamine intoxication outbreaks that may be better explained by the existence of interindividual susceptibility to ingested histamine.","PeriodicalId":284374,"journal":{"name":"Prime Archives in Nutrition","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128055942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Household Food Insecurity as a Predictor of Stunted Children and Overweight/ Obese Mothers (SCOWT) in Urban Indonesia","authors":"Trias Mahmudiono, Triska Susila Nindya, Dini Ririn Andrias, H. Megatsari, R. Rosenkranz","doi":"10.37247/pan.1.2020.7","DOIUrl":"https://doi.org/10.37247/pan.1.2020.7","url":null,"abstract":"","PeriodicalId":284374,"journal":{"name":"Prime Archives in Nutrition","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128741747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}