Spinal Surgery最新文献_第9页

Chiari I型奇形に伴う脊髄空洞症における難治性感覚障害例の形態学的・電気生理学的検討 Chiari I型畸形导致脊髓空洞症的难治性感觉障碍实例的形态学和电生理学探讨

Spinal Surgery Pub Date : 2004-03-31 DOI: 10.2531/SPINALSURG.18.9

靖人野田, 俊昭阿部, 晃磯島, 芳士奥田, 泰弘長島

{"title":"Chiari I型奇形に伴う脊髄空洞症における難治性感覚障害例の形態学的・電気生理学的検討","authors":"靖人野田, 俊昭阿部, 晃磯島, 芳士奥田, 泰弘長島","doi":"10.2531/SPINALSURG.18.9","DOIUrl":"https://doi.org/10.2531/SPINALSURG.18.9","url":null,"abstract":"Morphological and electrophysiological analysis was conducted to elucidate the pathophysiology which causes the discrepancy between radiological and clinical findings in post-operative syringomyelic patients with Chiari type I malformation. MRI analysis were performed on 28 cases of syringomyelia treated in our institute from 1988 to 1995 diagnosed with Chiari type I malformation with hemi-lateral symptoms in which the syrinx postoperatively collapsed or shrank. The expansion of syrinx in the direction of posterior gray horn was measured at the C6 level from the pre-operative MRI findings and compared with the outcome. A significant difference in the expansion of syrinx in the direction of posterior gray horn was found between improved and non-improved group. Median nerve somatosensory evoked potential (SEP) was carried out bilaterally on 13 patients and lower cervical N13 (lcN13), which is presumed to display the post-synaptic potential of posterior gray horn, was monitored. The diminishing rate of the lcN13 amplitude of the symptomatic side was measured in relation to the contralateral side. In all of the 13 patients, the amplitude of lcN13 was minimized in the symptomatic side. A significant difference in the diminishing rate of lcN13 was found between the improved and non-improved groups. The expansion of the pre-operative syrinx is related to the diminishing rate of lcN13. There seems to be a common marginal limit between the expansion of syrinx and the reduction of the potential of posterior gray horn in the transition of the outcome. The results from this study suggest that irreversible damage of posterior gray horn is the cause of discrepancy between radiological and clinical findings.","PeriodicalId":283326,"journal":{"name":"Spinal Surgery","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134124787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

An Osteoblast Differentiation Promoting Compound, TAK-778, combined with β-Tricalcium Phosphate used for Packing Interbody Fusion Cages 一种促进成骨细胞分化的化合物TAK-778与β-磷酸三钙联合用于填充椎间融合笼

Spinal Surgery Pub Date : 2003-11-30 DOI: 10.2531/SPINALSURG.17.183_2

T. Ohyama, Y. Kubo, H. Iwata, W. Taki

{"title":"An Osteoblast Differentiation Promoting Compound, TAK-778, combined with β-Tricalcium Phosphate used for Packing Interbody Fusion Cages","authors":"T. Ohyama, Y. Kubo, H. Iwata, W. Taki","doi":"10.2531/SPINALSURG.17.183_2","DOIUrl":"https://doi.org/10.2531/SPINALSURG.17.183_2","url":null,"abstract":"A synthetic 3-benzothiepin derivative, TAK-778, promotes osteoblast differentiation. If a mixture of TAK-778 and fi -tricalcium phosphate ( 6 -TCP) can be a substitute for autografts used for packing interbody fusion cages, donor-site related complications should be avoided. The lumbar vertebrae from Ll to L5 were exposed in 8 dogs using a posterolateral approach, and discectomy and interbody cage fusion were perfbrrned in three disc spaces. In group A, the cage was fiILed with autograft bone, in group B with fi -TCP, and in group C with fi -TCP and TAK-778. The Lumbar spine was excised at 16 weeks post-surgery, and mechanical, microradiographical and histological evaluations were made. The microradiographical and histological examinations revealed four fusions in eight operations in group A (50.0%), three in group B (37.5%), and five in group C (62.5%). The mean percentage of trabecular bone area in the cages was 53.4% in group A, 45.6% in group B and 64.4% in group C. Although the effect was not significant, addition of TAK-778 to 6 -TCP had some beneficial influence and there was a trend toward an improved fusion status in cages filled with fi -TCP and TAK-778. 6-TCP combined with TAK-778 could be used as a substitute for autografts in clinical spine surgery, especially for those patients who are anticipated to have a poor graft bone status, Key word: TAK-778, Tricalcium Phosphate, Cervical lnterbody Fusion Cage Spinal Surgery 17 (3):183N194, 2003, Autograft, Osteoinduction","PeriodicalId":283326,"journal":{"name":"Spinal Surgery","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2003-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130920907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

肘部管症候群 32 例の臨床的検討 : 特にその手術方法について 32例肘部管综合征的临床研究:特别是手术方法。

Spinal Surgery Pub Date : 2003-11-30 DOI: 10.2531/SPINALSURG.17.233

昌浩川西, 巌西浦, 聡森元, 肇半田

引用次数: 0

繰り返す頭痛にて発症した馬尾部 myxopapillary ependymoma の 1 例马尾myxopapillary ependymoma的一例反复头痛

Spinal Surgery Pub Date : 2003-11-30 DOI: 10.2531/SPINALSURG.17.245

Tomohiko Numoto, Hideki Arakawa, T. Terao, Hiromichi Nakazaki, S. Sawauchi, Toshiaki Abe

引用次数: 0

多椎間頚椎 OPLL に対するβ-tricalcium phosphate を応用した前側方部分椎体削開術の短期成績应用β-tricalcium phosphate治疗多椎间颈椎OPLL的前侧部分椎体削开术的短期成绩

Spinal Surgery Pub Date : 2003-11-30 DOI: 10.2531/SPINALSURG.17.203

文行門間, 照夫中沢